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Enhancing CRISPR prime editing by reducing misfolded pegRNA interactions.
- Published in:
- eLife, 2024, p. 1, doi. 10.7554eLife.90948
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- Publication type:
- Article
Functional analysis of Collagen 17a1: A genetic modifier of junctional epidermolysis bullosa in mice.
- Published in:
- PLoS ONE, 2023, v. 18, n. 10, p. 1, doi. 10.1371/journal.pone.0292456
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- Publication type:
- Article
Engineered CRISPR prime editors with compact, untethered reverse transcriptases.
- Published in:
- Nature Biotechnology, 2023, v. 41, n. 3, p. 337, doi. 10.1038/s41587-022-01473-1
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- Publication type:
- Article
CRISPR prime editing with ribonucleoprotein complexes in zebrafish and primary human cells.
- Published in:
- Nature Biotechnology, 2022, v. 40, n. 2, p. 189, doi. 10.1038/s41587-021-00901-y
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- Publication type:
- Article
Author Correction: CRISPR prime editing with ribonucleoprotein complexes in zebrafish and primary human cells.
- Published in:
- 2022
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- Publication type:
- Correction Notice
Defining genome-wide CRISPR–Cas genome-editing nuclease activity with GUIDE-seq.
- Published in:
- Nature Protocols, 2021, v. 16, n. 12, p. 5592, doi. 10.1038/s41596-021-00626-x
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- Publication type:
- Article
Scalable characterization of the PAM requirements of CRISPR–Cas enzymes using HT-PAMDA.
- Published in:
- Nature Protocols, 2021, v. 16, n. 3, p. 1511, doi. 10.1038/s41596-020-00465-2
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- Publication type:
- Article
PrimeDesign software for rapid and simplified design of prime editing guide RNAs.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-21337-7
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- Publication type:
- Article
CRISPR C-to-G base editors for inducing targeted DNA transversions in human cells.
- Published in:
- Nature Biotechnology, 2021, v. 39, n. 1, p. 41, doi. 10.1038/s41587-020-0609-x
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- Publication type:
- Article
Optimization of AsCas12a for combinatorial genetic screens in human cells.
- Published in:
- Nature Biotechnology, 2021, v. 39, n. 1, p. 94, doi. 10.1038/s41587-020-0600-6
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- Publication type:
- Article
A dual-deaminase CRISPR base editor enables concurrent adenine and cytosine editing.
- Published in:
- Nature Biotechnology, 2020, v. 38, n. 7, p. 861, doi. 10.1038/s41587-020-0535-y
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- Publication type:
- Article
Publisher Correction: Engineered CRISPR–Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing.
- Published in:
- 2020
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- Publication type:
- Correction Notice
Zebrafish dscamll Deficiency Impairs Retinal Patterning and Oculomotor Function.
- Published in:
- Journal of Neuroscience, 2020, v. 40, n. 1, p. 143, doi. 10.1523/jneurosci.1783-19.2019
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- Publication type:
- Article
High levels of AAV vector integration into CRISPR-induced DNA breaks.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-12449-2
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- Publication type:
- Article
CRISPR DNA base editors with reduced RNA off-target and self-editing activities.
- Published in:
- Nature Biotechnology, 2019, v. 37, n. 9, p. 1041, doi. 10.1038/s41587-019-0236-6
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- Publication type:
- Article
CRISPResso2 provides accurate and rapid genome editing sequence analysis.
- Published in:
- Nature Biotechnology, 2019, v. 37, n. 3, p. 224, doi. 10.1038/s41587-019-0032-3
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- Publication type:
- Article
Engineered CRISPR-Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing.
- Published in:
- Nature Biotechnology, 2019, v. 37, n. 3, p. 276, doi. 10.1038/s41587-018-0011-0
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- Publication type:
- Article
Activities and specificities of CRISPR/Cas9 and Cas12a nucleases for targeted mutagenesis in maize.
- Published in:
- Plant Biotechnology Journal, 2019, v. 17, n. 2, p. 362, doi. 10.1111/pbi.12982
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- Publication type:
- Article
Defining CRISPR-Cas9 genome-wide nuclease activities with CIRCLE-seq.
- Published in:
- Nature Protocols, 2018, v. 13, n. 11, p. 2615, doi. 10.1038/s41596-018-0055-0
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- Publication type:
- Article
An APOBEC3A-Cas9 base editor with minimized bystander and off-target activities.
- Published in:
- Nature Biotechnology, 2018, v. 36, n. 10, p. 977, doi. 10.1038/nbt.4199
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- Publication type:
- Article
Nodal patterning without Lefty inhibitory feedback is functional but fragile.
- Published in:
- eLife, 2017, p. 1, doi. 10.7554/eLife.28785.001
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- Publication type:
- Article
Genome-wide specificities of CRISPR-Cas Cpf1 nucleases in human cells.
- Published in:
- Nature Biotechnology, 2016, v. 34, n. 8, p. 869, doi. 10.1038/nbt.3620
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- Publication type:
- Article
Open-source guideseq software for analysis of GUIDE-seq data.
- Published in:
- Nature Biotechnology, 2016, v. 34, n. 5, p. 483, doi. 10.1038/nbt.3534
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- Publication type:
- Article
Broadening the targeting range of Staphylococcus aureus CRISPR-Cas9 by modifying PAM recognition.
- Published in:
- Nature Biotechnology, 2015, v. 33, n. 12, p. 1293, doi. 10.1038/nbt.3404
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- Publication type:
- Article
Accelerating research through reagent repositories: the genome editing example.
- Published in:
- Genome Biology, 2015, v. 16, p. 1, doi. 10.1186/s13059-015-0830-y
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- Publication type:
- Article
CAUSEL: an epigenome- and genome-editing pipeline for establishing function of noncoding GWAS variants.
- Published in:
- Nature Medicine, 2015, v. 21, n. 11, p. 1357, doi. 10.1038/nm.3975
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- Publication type:
- Article
Continuous directed evolution of DNA-binding proteins to improve TALEN specificity.
- Published in:
- Nature Methods, 2015, v. 12, n. 10, p. 939, doi. 10.1038/nmeth.3515
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- Publication type:
- Article
Engineered CRISPR-Cas9 nucleases with altered PAM specificities.
- Published in:
- Nature, 2015, v. 523, n. 7561, p. 481, doi. 10.1038/nature14592
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- Publication type:
- Article
Unwanted mutations: Standards needed for gene-editing errors.
- Published in:
- 2015
- By:
- Publication type:
- Letter to the Editor
Context influences on TALE-DNA binding revealed by quantitative profiling.
- Published in:
- Nature Communications, 2015, v. 6, n. 6, p. 7440, doi. 10.1038/ncomms8440
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- Publication type:
- Article
Genome Editing Technologies: Defining a Path to Clinic.
- Published in:
- Molecular Therapy, 2015, v. 23, n. 5, p. 796, doi. 10.1038/mt.2015.54
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- Publication type:
- Article
Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells.
- Published in:
- Nature Genetics, 2015, v. 47, n. 5, p. 469, doi. 10.1038/ng.3258
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- Publication type:
- Article
Rescue of DNA-PK Signaling and T-Cell Differentiation by Targeted Genome Editing in a prkdc Deficient iPSC Disease Model.
- Published in:
- PLoS Genetics, 2015, v. 11, n. 5, p. 1, doi. 10.1371/journal.pgen.1005239
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- Publication type:
- Article
Chromatin regulation at the frontier of synthetic biology.
- Published in:
- Nature Reviews Genetics, 2015, v. 16, n. 3, p. 159, doi. 10.1038/nrg3900
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- Publication type:
- Article
GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases.
- Published in:
- Nature Biotechnology, 2015, v. 33, n. 2, p. 187, doi. 10.1038/nbt.3117
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- Publication type:
- Article
Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo.
- Published in:
- Nature Biotechnology, 2015, v. 33, n. 1, p. 73, doi. 10.1038/nbt.3081
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- Publication type:
- Article
Genome Editing: A Tool For Research and Therapy: Towards a functional understanding of variants for molecular diagnostics using genome editing.
- Published in:
- Nature Medicine, 2014, v. 20, n. 10, p. 1103, doi. 10.1038/nm.3722
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- Publication type:
- Article
Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing.
- Published in:
- Nature Biotechnology, 2014, v. 32, n. 6, p. 569, doi. 10.1038/nbt.2908
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- Publication type:
- Article
An improved predictive recognition model for Cys2-His2 zinc finger proteins.
- Published in:
- Nucleic Acids Research, 2014, v. 42, n. 8, p. 4800, doi. 10.1093/nar/gku132
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- Publication type:
- Article
CRISPR-Cas systems for editing, regulating and targeting genomes.
- Published in:
- Nature Biotechnology, 2014, v. 32, n. 4, p. 347, doi. 10.1038/nbt.2842
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- Publication type:
- Article
Broad specificity profiling of TALENs results in engineered nucleases with improved DNA-cleavage specificity.
- Published in:
- Nature Methods, 2014, v. 11, n. 4, p. 429, doi. 10.1038/nmeth.2845
- By:
- Publication type:
- Article
Improving CRISPR-Cas nuclease specificity using truncated guide RNAs.
- Published in:
- Nature Biotechnology, 2014, v. 32, n. 3, p. 279, doi. 10.1038/nbt.2808
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- Publication type:
- Article
Locus-specific editing of histone modifications at endogenous enhancers.
- Published in:
- Nature Biotechnology, 2013, v. 31, n. 12, p. 1133, doi. 10.1038/nbt.2701
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- Publication type:
- Article
Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins.
- Published in:
- Nature Biotechnology, 2013, v. 31, n. 12, p. 1137, doi. 10.1038/nbt.2726
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- Publication type:
- Article
CRISPR RNA-guided activation of endogenous human genes.
- Published in:
- Nature Methods, 2013, v. 10, n. 10, p. 977, doi. 10.1038/nmeth.2598
- By:
- Publication type:
- Article
In silico abstraction of zinc finger nuclease cleavage profiles reveals an expanded landscape of off-target sites.
- Published in:
- Nucleic Acids Research, 2013, v. 41, n. 19, p. e181, doi. 10.1093/nar/gkt716
- By:
- Publication type:
- Article
High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells.
- Published in:
- Nature Biotechnology, 2013, v. 31, n. 9, p. 822, doi. 10.1038/nbt.2623
- By:
- Publication type:
- Article
Heritable and Precise Zebrafish Genome Editing Using a CRISPR-Cas System.
- Published in:
- PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0068708
- By:
- Publication type:
- Article
TALEN-based Gene Correction for Epidermolysis Bullosa.
- Published in:
- Molecular Therapy, 2013, v. 21, n. 6, p. 1151, doi. 10.1038/mt.2013.56
- By:
- Publication type:
- Article
Identification of promoter targets of enhancers by epigenetic knockdown using TAL DNA binding proteins.
- Published in:
- 2013
- By:
- Publication type:
- Conference Paper