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RNA binding protein SYNCRIP maintains proteostasis and self-renewal of hematopoietic stem and progenitor cells.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38001-x
By:
- Herrejon Chavez, Florisela;
- Luo, Hanzhi;
- Cifani, Paolo;
- Pine, Alli;
- Chu, Karen L.;
- Joshi, Suhasini;
- Barin, Ersilia;
- Schurer, Alexandra;
- Chan, Mandy;
- Chang, Kathryn;
- Han, Grace Y. Q.;
- Pierson, Aspen J.;
- Xiao, Michael;
- Yang, Xuejing;
- Kuehm, Lindsey M.;
- Hong, Yuning;
- Nguyen, Diu T. T.;
- Chiosis, Gabriela;
- Kentsis, Alex;
- Leslie, Christina
Publication type:
Article
Genetically engineered mucin mouse models for inflammation and cancer.
Published in:
Cancer & Metastasis Reviews, 2015, v. 34, n. 4, p. 593, doi. 10.1007/s10555-015-9549-1
By:
- Joshi, Suhasini;
- Kumar, Sushil;
- Bafna, Sangeeta;
- Rachagani, Satyanarayana;
- Wagner, Kay-Uwe;
- Jain, Maneesh;
- Batra, Surinder
Publication type:
Article
Pharmacologically controlling protein-protein interactions through epichaperomes for therapeutic vulnerability in cancer.
Published in:
Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02842-3
By:
- Joshi, Suhasini;
- Gomes, Erica DaGama;
- Wang, Tai;
- Corben, Adriana;
- Taldone, Tony;
- Gandu, Srinivasa;
- Xu, Chao;
- Sharma, Sahil;
- Buddaseth, Salma;
- Yan, Pengrong;
- Chan, Lon Yin L.;
- Gokce, Askan;
- Rajasekhar, Vinagolu K.;
- Shrestha, Lisa;
- Panchal, Palak;
- Almodovar, Justina;
- Digwal, Chander S.;
- Rodina, Anna;
- Merugu, Swathi;
- Pillarsetty, NagaVaraKishore
Publication type:
Article
Chemical tools for epichaperome-mediated interactome dysfunctions of the central nervous system.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24821-2
By:
- Bolaender, Alexander;
- Zatorska, Danuta;
- He, Huazhong;
- Joshi, Suhasini;
- Sharma, Sahil;
- Digwal, Chander S.;
- Patel, Hardik J.;
- Sun, Weilin;
- Imber, Brandon S.;
- Ochiana, Stefan O.;
- Patel, Maulik R.;
- Shrestha, Liza;
- Shah, Smit. K.;
- Wang, Shuo;
- Karimov, Rashad;
- Tao, Hui;
- Patel, Pallav D.;
- Martin, Ananda Rodilla;
- Yan, Pengrong;
- Panchal, Palak
Publication type:
Article
Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39241-7
By:
- Rodina, Anna;
- Xu, Chao;
- Digwal, Chander S.;
- Joshi, Suhasini;
- Patel, Yogita;
- Santhaseela, Anand R.;
- Bay, Sadik;
- Merugu, Swathi;
- Alam, Aftab;
- Yan, Pengrong;
- Yang, Chenghua;
- Roychowdhury, Tanaya;
- Panchal, Palak;
- Shrestha, Liza;
- Kang, Yanlong;
- Sharma, Sahil;
- Almodovar, Justina;
- Corben, Adriana;
- Alpaugh, Mary L.;
- Modi, Shanu
Publication type:
Article
Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39241-7
By:
- Rodina, Anna;
- Xu, Chao;
- Digwal, Chander S.;
- Joshi, Suhasini;
- Patel, Yogita;
- Santhaseela, Anand R.;
- Bay, Sadik;
- Merugu, Swathi;
- Alam, Aftab;
- Yan, Pengrong;
- Yang, Chenghua;
- Roychowdhury, Tanaya;
- Panchal, Palak;
- Shrestha, Liza;
- Kang, Yanlong;
- Sharma, Sahil;
- Almodovar, Justina;
- Corben, Adriana;
- Alpaugh, Mary L.;
- Modi, Shanu
Publication type:
Article
The penalty of stress ‐ Epichaperomes negatively reshaping the brain in neurodegenerative disorders.
Published in:
Journal of Neurochemistry, 2021, v. 159, n. 6, p. 958, doi. 10.1111/jnc.15525
By:
- Ginsberg, Stephen D.;
- Joshi, Suhasini;
- Sharma, Sahil;
- Guzman, Gianny;
- Wang, Tai;
- Arancio, Ottavio;
- Chiosis, Gabriela
Publication type:
Article
HSP90-incorporating chaperome networks as biosensor for disease-related pathways in patient-specific midbrain dopamine neurons.
Published in:
Nature Communications, 2018, v. 9, p. 1, doi. 10.1038/s41467-018-06486-6
By:
- Kishinevsky, Sarah;
- Tai Wang;
- Rodina, Anna;
- Sun Young Chung;
- Chao Xu;
- Philip, John;
- Taldone, Tony;
- Joshi, Suhasini;
- Alpaugh, Mary L.;
- Bolaender, Alexander;
- Gutbier, Simon;
- Sandhu, Davinder;
- Fattahi, Faranak;
- Zimmer, Bastian;
- Shah, Smit K.;
- Chang, Elizabeth;
- Inda, Carmen;
- Koren 3rd, John;
- Saurat, Nathalie G.;
- Leist, Marcel
Publication type:
Article
Genetic variants of mucins: unexplored conundrum.
Published in:
Carcinogenesis, 2017, v. 38, n. 7, p. 671, doi. 10.1093/carcin/bgw120
By:
- Kumar, Sushil;
- Cruz, Eric;
- Joshi, Suhasini;
- Patel, Asish;
- Jahan, Rahat;
- Batra, Surinder K.;
- Jain, Maneesh
Publication type:
Article
Unraveling the Mechanism of Epichaperome Modulation by Zelavespib: Biochemical Insights on Target Occupancy and Extended Residence Time at the Site of Action.
Published in:
Biomedicines, 2023, v. 11, n. 10, p. 2599, doi. 10.3390/biomedicines11102599
By:
- Sharma, Sahil;
- Joshi, Suhasini;
- Kalidindi, Teja;
- Digwal, Chander S.;
- Panchal, Palak;
- Lee, Sang-Gyu;
- Zanzonico, Pat;
- Pillarsetty, Nagavarakishore;
- Chiosis, Gabriela
Publication type:
Article
Structurally symmetric near-infrared fluorophore IRDye78-protein complex enables multimodal cancer imaging.
Published in:
Theranostics, 2021, v. 11, n. 6, p. 2534, doi. 10.7150/thno.54928
By:
- Jiang Yang;
- Chunhua Zhao;
- Jacky Lim;
- Lina Zhao;
- Le Tourneau, Ryan;
- Qize Zhang;
- Dobson, Damien;
- Joshi, Suhasini;
- Jiadong Pang;
- Xiaodong Zhang;
- Pal, Suchetan;
- Andreou, Chrysafis;
- Hanwen Zhang;
- Kircher, Moritz F.;
- Schmitthenner, Hans
Publication type:
Article
Phosphorylation-driven epichaperome assembly is a regulator of cellular adaptability and proliferation.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-53178-5
By:
- Roychowdhury, Tanaya;
- McNutt, Seth W.;
- Pasala, Chiranjeevi;
- Nguyen, Hieu T.;
- Thornton, Daniel T.;
- Sharma, Sahil;
- Botticelli, Luke;
- Digwal, Chander S.;
- Joshi, Suhasini;
- Yang, Nan;
- Panchal, Palak;
- Chakrabarty, Souparna;
- Bay, Sadik;
- Markov, Vladimir;
- Kwong, Charlene;
- Lisanti, Jeanine;
- Chung, Sun Young;
- Ginsberg, Stephen D.;
- Yan, Pengrong;
- De Stanchina, Elisa
Publication type:
Article
Phosphorylation-driven epichaperome assembly is a regulator of cellular adaptability and proliferation.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-53178-5
By:
- Roychowdhury, Tanaya;
- McNutt, Seth W.;
- Pasala, Chiranjeevi;
- Nguyen, Hieu T.;
- Thornton, Daniel T.;
- Sharma, Sahil;
- Botticelli, Luke;
- Digwal, Chander S.;
- Joshi, Suhasini;
- Yang, Nan;
- Panchal, Palak;
- Chakrabarty, Souparna;
- Bay, Sadik;
- Markov, Vladimir;
- Kwong, Charlene;
- Lisanti, Jeanine;
- Chung, Sun Young;
- Ginsberg, Stephen D.;
- Yan, Pengrong;
- De Stanchina, Elisa
Publication type:
Article
The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-019-14082-5
By:
- Inda, Maria Carmen;
- Joshi, Suhasini;
- Wang, Tai;
- Bolaender, Alexander;
- Gandu, Srinivasa;
- Koren III, John;
- Che, Alicia Yue;
- Taldone, Tony;
- Yan, Pengrong;
- Sun, Weilin;
- Uddin, Mohammad;
- Panchal, Palak;
- Riolo, Matthew;
- Shah, Smit;
- Barlas, Afsar;
- Xu, Ke;
- Chan, Lon Yin L.;
- Gruzinova, Alexandra;
- Kishinevsky, Sarah;
- Studer, Lorenz
Publication type:
Article
Bile acids-mediated overexpression of MUC4 via FAK-dependent c-Jun activation in pancreatic cancer.
Published in:
Molecular Oncology, 2016, v. 10, n. 7, p. 1063, doi. 10.1016/j.molonc.2016.04.007
By:
- Joshi, Suhasini;
- Cruz, Eric;
- Rachagani, Satyanarayana;
- Guha, Sushovan;
- Brand, Randall E.;
- Ponnusamy, Moorthy P.;
- Kumar, Sushil;
- Batra, Surinder K.
Publication type:
Article

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