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Atypical Scrapie Prions from Sheep and Lack of Disease in Transgenic Mice Overexpressing Human Prion Protein.
Published in:
Emerging Infectious Diseases, 2013, v. 19, n. 11, p. 1731, doi. 10.3201/eid1911.121341
By:
- Wadsworth, Jonathan D. F.;
- Joiner, Susan;
- Linehan, Jacqueline M.;
- Balkema-Buschmann, Anne;
- Spiropoulos, John;
- Simmons, Marion M.;
- Griffiths, Peter C.;
- Groschup, Martin H.;
- Hope, James;
- Brandner, Sebastian;
- Asante, Emmanuel A.;
- Collinge, John
Publication type:
Article
2.7 Å cryo-EM structure of ex vivo RML prion fibrils.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-30457-7
By:
- Manka, Szymon W.;
- Zhang, Wenjuan;
- Wenborn, Adam;
- Betts, Jemma;
- Joiner, Susan;
- Saibil, Helen R.;
- Collinge, John;
- Wadsworth, Jonathan D. F.
Publication type:
Article
BSE prions propagate as either variant CJD-like or sporadic CJD-like prion strains in transgenic mice expressing human prion protein.
Published in:
EMBO Journal, 2002, v. 21, n. 23, p. 6358, doi. 10.1093/emboj/cdf653
By:
- Asante, Emmanuel A.;
- Linehan, Jacqueline M.;
- Desbruslais, Melanie;
- Joiner, Susan;
- Gowland, Ian;
- Wood, Andrew L.;
- Welch, Julie;
- Hill, Andrew F.;
- Lloyd, Sarah E.;
- Wadsworth, Jonathan D. F.;
- Collinge, John
Publication type:
Article
Effect of fixation on brain and lymphoreticular vCJD prions and bioassay of key positive specimens from a retrospective vCJD prevalence study.
Published in:
Journal of Pathology, 2011, v. 223, n. 4, p. 511, doi. 10.1002/path.2821
By:
- Wadsworth, Jonathan DF;
- Dalmau-Mena, Inmaculada;
- Joiner, Susan;
- Linehan, Jacqueline M;
- O'Malley, Catherine;
- Powell, Caroline;
- Brandner, Sebastian;
- Asante, Emmanuel A;
- Ironside, James W;
- Hilton, David A;
- Collinge, John
Publication type:
Article
Isolation of Proteinase K-Sensitive Prions Using Pronase E and Phosphotungstic Acid.
Published in:
PLoS ONE, 2010, v. 5, n. 12, p. 1, doi. 10.1371/journal.pone.0015679
By:
- D'Castro, Laura;
- Wenborn, Adam;
- Gros, Nathalie;
- Joiner, Susan;
- Cronier, Sabrina;
- Collinge, John;
- Wadsworth, Jonathan D. F.
Publication type:
Article
Strain-specific prion-protein conformation determined by metal ions.
Published in:
Nature Cell Biology, 1999, v. 1, n. 1, p. 55, doi. 10.1038/9030
By:
- Wadsworth, Jonathan D.F.;
- Hill, Andrew F.;
- Joiner, Susan;
- Jackson, Graham S.;
- Clarke, Anthony R.;
- Collinge, John
Publication type:
Article
Inherited prion disease with 4-octapeptide repeat insertion: disease requires the interaction of multiple genetic risk factors.
Published in:
Brain: A Journal of Neurology, 2011, v. 134, n. 6, p. 1829, doi. 10.1093/brain/awr079
By:
- Kaski, Diego N.;
- Pennington, Catherine;
- Beck, Jon;
- Poulter, Mark;
- Uphill, James;
- Bishop, Matthew T.;
- Linehan, Jaqueline M.;
- O’Malley, Catherine;
- Wadsworth, Jonathan D. F.;
- Joiner, Susan;
- Knight, Richard S. G.;
- Ironside, James W.;
- Brandner, Sebastian;
- Collinge, John;
- Mead, Simon
Publication type:
Article
Inherited prion disease with six octapeptide repeat insertional mutation--molecular analysis of phenotypic heterogeneity.
Published in:
2006
By:
- Mead S;
- Poulter M;
- Beck J;
- Webb TE;
- Campbell TA;
- Linehan JM;
- Desbruslais M;
- Joiner S;
- Wadsworth JD;
- King A;
- Lantos P;
- Collinge J;
- Mead, Simon;
- Poulter, Mark;
- Beck, Jon;
- Webb, Thomas E F;
- Campbell, Tracy A;
- Linehan, Jacqueline M;
- Desbruslais, Melanie;
- Joiner, Susan
Publication type:
journal article
Inherited prion disease with six octapeptide repeat insertional mutation—molecular analysis of phenotypic heterogeneity.
Published in:
Brain: A Journal of Neurology, 2006, v. 129, n. 9, p. 2297, doi. 10.1093/brain/awl226
By:
- Simon Mead;
- Mark Poulter;
- Jon Beck;
- Thomas E. F. Webb;
- Tracy A. Campbell;
- Jacqueline M. Linehan;
- Melanie Desbruslais;
- Susan Joiner;
- Jonathan D. F. Wadsworth;
- Andrew King;
- Peter Lantos;
- John Collinge
Publication type:
Article
Phenotypic heterogeneity in inherited prion disease (P102L) is associated with differential propagation of protease-resistant wild-type and mutant prion protein.
Published in:
2006
By:
- Wadsworth JD;
- Joiner S;
- Linehan JM;
- Cooper S;
- Powell C;
- Mallinson G;
- Buckell J;
- Gowland I;
- Asante EA;
- Budka H;
- Brandner S;
- Collinge J;
- Wadsworth, Jonathan D F;
- Joiner, Susan;
- Linehan, Jacqueline M;
- Cooper, Sharon;
- Powell, Caroline;
- Mallinson, Gary;
- Buckell, Jennifer;
- Gowland, Ian
Publication type:
journal article
Phenotypic heterogeneity in inherited prion disease (P102L) is associated with differential propagation of protease-resistant wild-type and mutant prion protein.
Published in:
Brain: A Journal of Neurology, 2006, v. 129, n. 6, p. 1557
By:
- Jonathan D. F. Wadsworth;
- Susan Joiner;
- Jacqueline M. Linehan;
- Sharon Cooper;
- Caroline Powell;
- Gary Mallinson;
- Jennifer Buckell;
- Ian Gowland;
- Emmanuel A. Asante;
- Herbert Budka;
- Sebastian Brandner;
- John Collinge
Publication type:
Article
Transmission Properties of Human PrP 102L Prions Challenge the Relevance of Mouse Models of GSS.
Published in:
PLoS Pathogens, 2015, v. 11, n. 7, p. 1, doi. 10.1371/journal.ppat.1004953
By:
- Asante, Emmanuel A.;
- Grimshaw, Andrew;
- Smidak, Michelle;
- Jakubcova, Tatiana;
- Tomlinson, Andrew;
- Jeelani, Asif;
- Hamdan, Shyma;
- Powell, Caroline;
- Joiner, Susan;
- Linehan, Jacqueline M.;
- Brandner, Sebastian;
- Wadsworth, Jonathan D. F.;
- Collinge, John
Publication type:
Article
A novel and rapid method for obtaining high titre intact prion strains from mammalian brain.
Published in:
Scientific Reports, 2015, p. 10062, doi. 10.1038/srep10062
By:
- Wenborn, Adam;
- Terry, Cassandra;
- Gros, Nathalie;
- Joiner, Susan;
- D'Castro, Laura;
- Sells, Jessica;
- Cronier, Sabrina;
- Linehan, Jacqueline M.;
- Brandner, Sebastian;
- Collinge, John;
- Wadsworth, Jonathan D. F.;
- Panico, Silvia;
- Saibil, Helen R.
Publication type:
Article
Structural features distinguishing infectious ex vivo mammalian prions from non-infectious fibrillar assemblies generated in vitro.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-018-36700-w
By:
- Terry, Cassandra;
- Harniman, Robert L.;
- Sells, Jessica;
- Wenborn, Adam;
- Joiner, Susan;
- Saibil, Helen R.;
- Miles, Mervyn J.;
- Collinge, John;
- Wadsworth, Jonathan D. F.
Publication type:
Article
Humanized Transgenic Mice Are Resistant to Chronic Wasting Disease Prions From Norwegian Reindeer and Moose.
Published in:
2022
By:
- Wadsworth, Jonathan D F;
- Joiner, Susan;
- Linehan, Jacqueline M;
- Jack, Kezia;
- Al-Doujaily, Huda;
- Costa, Helena;
- Ingold, Thea;
- Taema, Maged;
- Zhang, Fuquan;
- Sandberg, Malin K;
- Brandner, Sebastian;
- Tran, Linh;
- Vikøren, Turid;
- Våge, Jørn;
- Madslien, Knut;
- Ytrehus, Bjørnar;
- Benestad, Sylvie L;
- Asante, Emmanuel A;
- Collinge, John
Publication type:
journal article

Found: 15