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Phase 1b study of a small molecule antagonist of human chemokine (C-C motif) receptor 2 (PF-04136309) in combination with nab-paclitaxel/gemcitabine in first-line treatment of metastatic pancreatic ductal adenocarcinoma.
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- Investigational New Drugs, 2020, v. 38, n. 3, p. 800, doi. 10.1007/s10637-019-00830-3
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- Article
Longer Occupancy of Opioid Receptors by Nalmefene Compared to Naloxone as Measured In Vivo by a Dual-Detector System.
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- Journal of Nuclear Medicine, 1997, v. 38, n. 11, p. 1726
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- Article
The effects of single‐ and multiple‐dose administration of bococizumab (RN316/PF‐04950615), a humanized IgG2Δa monoclonal antibody binding proprotein convertase subtilisin/kexin type 9, in hypercholesterolemic subjects treated with and without atorvastatin: Results from four phase I studies
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- Cardiovascular Therapeutics, 2018, v. 36, n. 1, p. 1, doi. 10.1111/1755-5922.12309
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- Article
Effects of 12 weeks of treatment with intravenously administered bococizumab, a humanized monoclonal antibody blocking proprotein convertase subtilisin/kexin type 9, in hypercholesterolemic subjects on high‐dose statin.
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- Cardiovascular Therapeutics, 2018, v. 36, n. 1, p. 1, doi. 10.1111/1755-5922.12308
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- Article
Single and multiple ascending-dose study of glucagon-receptor antagonist RN909 in type 2 diabetes: a phase 1, randomized, double-blind, placebo-controlled trial.
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- Endocrine (1355008X), 2018, v. 62, n. 2, p. 371, doi. 10.1007/s12020-018-1597-1
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- Article
Model-Based Characterization of the Pharmacokinetics, Target Engagement Biomarkers, and Immunomodulatory Activity of PF-06342674, a Humanized mAb Against IL-7 Receptor-α, in Adults with Type 1 Diabetes.
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- AAPS Journal, 2020, v. 22, n. 2, p. 1, doi. 10.1208/s12248-019-0401-3
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- Article
Molecular Characterization of Familial Hypercholesterolemia in a North American Cohort.
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- Journal of the Endocrine Society, 2020, v. 4, n. 1, p. N.PAG, doi. 10.1210/jendso/bvz015
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- Article
A Mechanism-Based Pharmacokinetic/Pharmacodynamic Model for Bococizumab, a Humanized Monoclonal Antibody Against Proprotein Convertase Subtilisin/Kexin Type 9, and Its Application in Early Clinical Development.
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- Journal of Clinical Pharmacology, 2017, v. 57, n. 7, p. 855, doi. 10.1002/jcph.867
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- Article