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Structural basis of p53 inactivation by cavity-creating cancer mutations and its implications for the development of mutant p53 reactivators.
- Published in:
- Cell Death & Disease, 2024, v. 15, n. 6, p. 1, doi. 10.1038/s41419-024-06739-x
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- Article
Evolutionary history of the p53 family DNA-binding domain: insights from an Alvinella pompejana homolog.
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- Cell Death & Disease, 2022, v. 13, n. 3, p. 1, doi. 10.1038/s41419-022-04653-8
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- Article
Stabilising the DNA-binding domain of p53 by rational design of its hydrophobic core.
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- PEDS: Protein Engineering, Design & Selection, 2009, v. 22, n. 7, p. 421, doi. 10.1093/protein/gzp018
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- Article
Genotoxicity and Epigenotoxicity of Carbazole-Derived Molecules on MCF-7 Breast Cancer Cells.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 7, p. 3410, doi. 10.3390/ijms22073410
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- Article
Conservation of DNA-binding specificity and oligomerisationproperties within the p53 family.
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- BMC Genomics, 2009, v. 10, p. 628, doi. 10.1186/1471-2164-10-628
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- Article
Stabilization of mutant p53 via alkylation of cysteines and effects on DNA binding.
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- Protein Science: A Publication of the Protein Society, 2010, v. 19, n. 12, p. 2267, doi. 10.1002/pro.507
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- Article
The structure of the FYR domain of transforming growth factor beta regulator 1.
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- Protein Science: A Publication of the Protein Society, 2010, v. 19, n. 7, p. 1432, doi. 10.1002/pro.404
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- Article
Protein Evolution via Amino Acid and Codon Elimination.
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- PLoS ONE, 2010, v. 5, n. 4, p. 1, doi. 10.1371/journal.pone.0010104
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- Article
Small molecule induced reactivation of mutant p53 in cancer cells.
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- Nucleic Acids Research, 2013, v. 41, n. 12, p. 6034, doi. 10.1093/nar/gkt305
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- Article
Characterization of a dual BET/HDAC inhibitor for treatment of pancreatic ductal adenocarcinoma.
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- International Journal of Cancer, 2020, v. 147, n. 10, p. 2847, doi. 10.1002/ijc.33137
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- Article