Works by Jończyk, Jakub

Results: 21

New cyclopentaquinoline and 3,5-dichlorobenzoic acid hybrids with neuroprotection against oxidative stress for the treatment of Alzheimer's disease.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2023, v. 38, n. 1, p. 1, doi. 10.1080/14756366.2022.2158822

By:

Czarnecka, Kamila;
Girek, Małgorzata;
Kręcisz, Paweł;
Skibiński, Robert;
Łątka, Kamil;
Jończyk, Jakub;
Bajda, Marek;
Szymczyk, Piotr;
Galita, Grzegorz;
Kabziński, Jacek;
Majsterek, Ireneusz;
Espargaró, Alba;
Sabate, Raimon;
Szymański, Paweł

Publication type:

Article

Multidirectional in vitro and in cellulo studies as a tool for identification of multi-target-directed ligands aiming at symptoms and causes of Alzheimer's disease.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2020, v. 35, n. 1, p. 1944, doi. 10.1080/14756366.2020.1835882

By:

Szałaj, Natalia;
Godyń, Justyna;
Jończyk, Jakub;
Pasieka, Anna;
Panek, Dawid;
Wichur, Tomasz;
Więckowski, Krzysztof;
Zaręba, Paula;
Bajda, Marek;
Pislar, Anja;
Malawska, Barbara;
Sabate, Raimon;
Więckowska, Anna

Publication type:

Article

New cyclopentaquinoline hybrids with multifunctional capacities for the treatment of Alzheimer’s disease.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2018, v. 33, n. 1, p. 158, doi. 10.1080/14756366.2017.1406485

By:

Czarnecka, Kamila;
Girek, Małgorzata;
Maciejewska, Karolina;
Skibiński, Robert;
Jończyk, Jakub;
Bajda, Marek;
Kabziński, Jacek;
Sołowiej, Przemysław;
Majsterek, Ireneusz;
Szymański, Paweł

Publication type:

Article

Discovery of butyrylcholinesterase inhibitors among derivatives of azaphenothiazines.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2015, v. 30, n. 1, p. 98, doi. 10.3109/14756366.2014.889127

By:

Lodarski, Krzysztof;
Jończyk, Jakub;
Guzior, Natalia;
Bajda, Marek;
Gładysz, Joanna;
Walczyk, Joanna;
Jeleń, Małgorzata;
Morak-Młodawska, Beata;
Pluta, Krystian;
Malawska, Barbara

Publication type:

Article

Risk assessment of accidental exposure of surgeons to blood during orthopedic surgery. Are we safe in surgical gloves?

Published in:

Annals of Agricultural & Environmental Medicine, 2014, v. 21, n. 1, p. 212

By:

Timler, Dariusz;
Bończak, Oktawiusz;
Jończyk, Jakub;
Iltchev, Petre;
Śliwczyński, Andrzej;
Marczak, Michał

Publication type:

Article

Synthesis, In Vitro, and Computational Studies of PTP1B Phosphatase Inhibitors Based on Oxovanadium(IV) and Dioxovanadium(V) Complexes.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 13, p. 7034, doi. 10.3390/ijms23137034

By:

Kostrzewa, Tomasz;
Jończyk, Jakub;
Drzeżdżon, Joanna;
Jacewicz, Dagmara;
Górska-Ponikowska, Magdalena;
Kołaczkowski, Marcin;
Kuban-Jankowska, Alicja

Publication type:

Article

New Tetrahydroacridine Hybrids with Dichlorobenzoic Acid Moiety Demonstrating Multifunctional Potential for the Treatment of Alzheimer's Disease.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 11, p. 3765, doi. 10.3390/ijms21113765

By:

Czarnecka, Kamila;
Girek, Małgorzata;
Wójtowicz, Przemysław;
Kręcisz, Paweł;
Skibiński, Robert;
Jończyk, Jakub;
Łątka, Kamil;
Bajda, Marek;
Walczak, Anna;
Galita, Grzegorz;
Kabziński, Jacek;
Majsterek, Ireneusz;
Szymczyk, Piotr;
Szymański, Paweł

Publication type:

Article

Discovery of New Cyclopentaquinoline Analogues as Multifunctional Agents for the Treatment of Alzheimer's Disease.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 3, p. 498, doi. 10.3390/ijms20030498

By:

Czarnecka, Kamila;
Girek, Małgorzata;
Kręcisz, Paweł;
Skibiński, Robert;
Łątka, Kamil;
Jończyk, Jakub;
Bajda, Marek;
Kabziński, Jacek;
Majsterek, Ireneusz;
Szymczyk, Piotr;
Szymański, Paweł

Publication type:

Article

Application of Computational Methods for the Design of BACE-1 Inhibitors: Validation of in Silico Modelling.

Published in:

International Journal of Molecular Sciences, 2014, v. 15, n. 3, p. 5128, doi. 10.3390/ijms15035128

By:

Bajda, Marek;
Jończyk, Jakub;
Malawska, Barbara;
Filipek, Sławomir

Publication type:

Article

Hybrid approach to structure modeling of the histamine H3 receptor: Multi-level assessment as a tool for model verification.

Published in:

PLoS ONE, 2017, v. 12, n. 10, p. 1, doi. 10.1371/journal.pone.0186108

By:

Jończyk, Jakub;
Malawska, Barbara;
Bajda, Marek

Publication type:

Article

Multifunctional, Fluorene‐Based Modulator of Cholinergic and GABAergic Neurotransmission as a Novel Drug Candidate for Palliative Treatment of Alzheimer's Disease.

Published in:

Angewandte Chemie, 2025, v. 137, n. 6, p. 1, doi. 10.1002/ange.202420510

By:

Panek, Dawid;
Pasieka, Anna;
Jończyk, Jakub;
Gawlińska, Milena;
Zaręba, Paula;
Siwek, Agata;
Wolak, Małgorzata;
Mordyl, Barbara;
Głuch‐Lutwin, Monika;
Latacz, Gniewomir;
Brazzolotto, Xavier;
Chantegreil, Fabien;
Nachon, Florian;
Zdarova Karasova, Jana;
Pejchal, Jaroslav;
Mzik, Martin;
Sestak, Vit;
Prchal, Lukas;
Odvarkova, Jitka;
Soukup, Ondrej

Publication type:

Article

Inhibitors of SARS-CoV-2 Main Protease (Mpro) as Anti-Coronavirus Agents.

Published in:

Biomolecules (2218-273X), 2024, v. 14, n. 7, p. 797, doi. 10.3390/biom14070797

By:

Zagórska, Agnieszka;
Czopek, Anna;
Fryc, Monika;
Jończyk, Jakub

Publication type:

Article

Molecular Modeling Studies on the Multistep Reactivation Process of Organophosphate-Inhibited Acetylcholinesterase and Butyrylcholinesterase.

Published in:

Biomolecules (2218-273X), 2021, v. 11, n. 2, p. 169, doi. 10.3390/biom11020169

By:

Jończyk, Jakub;
Kukułowicz, Jędrzej;
Łątka, Kamil;
Malawska, Barbara;
Jung, Young-Sik;
Musilek, Kamil;
Bajda, Marek

Publication type:

Article

New Tacrine Analogs as Acetylcholinesterase Inhibitors -Theoretical Study with Chemometric Analysis.

Published in:

Molecules, 2013, v. 18, n. 3, p. 2878, doi. 10.3390/molecules18032878

By:

Szymański, Paweł;
Skibiński, Robert;
Inglot, Tadeusz;
Bajda, Marek;
Jończyk, Jakub;
Malawska, Barbara;
Mikiciuk-Olasik, Elżbieta

Publication type:

Article

Pathological Subtrochanteric Femoral Fracture Due to Extensive Arterio-venous Malformation. A Case Study.

Published in:

Orthopaedics, Traumatology, Rehabilitation / Ortopedia, Traumatologia, Rehabilitacja, 2015, v. 17, n. 3, p. 297, doi. 10.5604/15093492.1162429

By:

Jończyk, Jakub;
Szubert, Wojciech;
Panasiuk, Michał

Publication type:

Article

MOLECULAR MODELING IN SEARCH OF NEW, MULTI-TARGET LIGANDS AGAINST ALZHEIMER'S DISEASE. EXPLORING THE BIOCHEMICAL MULTIVERSE.

Published in:

Military Medical Science Letters / Vojenské zdravotnické Listy, 2018, v. 87, p. 75

By:

Jończyk, Jakub;
Panek, Dawid;
Więckowska, Anna;
Godyń, Justyna;
Bajda, Marek;
Wichur, Tomasz;
Pasieka, Anna;
Knez, Damijan;
Pišlar, Anja;
Korabecny, Jan;
Soukup, Ondrej;
Sepsova, Vendula;
Sabaté, Raimon;
Kos, Janko;
Gobec, Stanislav;
Malawska, Barbara

Publication type:

Article

Dual-Acting Diether Derivatives of Piperidine and Homopiperidine with Histamine H<sub>3</sub> Receptor Antagonistic and Anticholinesterase Activity.

Published in:

Archiv der Pharmazie, 2012, v. 345, n. 8, p. 591, doi. 10.1002/ardp.201200018

By:

Bajda, Marek;
Kuder, Kamil J.;
Łażewska, Dorota;
Kieć-Kononowicz, Katarzyna;
Więckowska, Anna;
Ignasik, Michalina;
Guzior, Natalia;
Jończyk, Jakub;
Malawska, Barbara

Publication type:

Article

Virtual Screening Approaches to Identify Promising Multitarget-Directed Ligands for the Treatment of Autism Spectrum Disorder.

Published in:

Molecules, 2024, v. 29, n. 22, p. 5271, doi. 10.3390/molecules29225271

By:

Jończyk, Jakub;
Przybylska, Klaudia;
Staszewski, Marek;
Godyń, Justyna;
Werner, Tobias;
Stefaniak-Napieralska, Monika;
Stark, Holger;
Walczyński, Krzysztof;
Bajda, Marek

Publication type:

Article

Dual Action of Dipyridothiazine and Quinobenzothiazine Derivatives—Anticancer and Cholinesterase-Inhibiting Activity.

Published in:

Molecules, 2020, v. 25, n. 11, p. 2604, doi. 10.3390/molecules25112604

By:

Jończyk, Jakub;
Godyń, Justyna;
Stawarska, Ewelina;
Morak-Młodawska, Beata;
Jeleń, Małgorzata;
Pluta, Krystian;
Malawska, Barbara;
Jean, Ludovic

Publication type:

Article

Multifunctional, Fluorene‐Based Modulator of Cholinergic and GABAergic Neurotransmission as a Novel Drug Candidate for Palliative Treatment of Alzheimer's Disease.

Published in:

Angewandte Chemie International Edition, 2025, v. 64, n. 6, p. 1, doi. 10.1002/anie.202420510

By:

Panek, Dawid;
Pasieka, Anna;
Jończyk, Jakub;
Gawlińska, Milena;
Zaręba, Paula;
Siwek, Agata;
Wolak, Małgorzata;
Mordyl, Barbara;
Głuch‐Lutwin, Monika;
Latacz, Gniewomir;
Brazzolotto, Xavier;
Chantegreil, Fabien;
Nachon, Florian;
Zdarova Karasova, Jana;
Pejchal, Jaroslav;
Mzik, Martin;
Sestak, Vit;
Prchal, Lukas;
Odvarkova, Jitka;
Soukup, Ondrej

Publication type:

Article

Characteristics of metabolic stability and the cell permeability of 2‐pyrimidinyl‐piperazinyl‐alkyl derivatives of 1H‐imidazo[2,1‐f]purine‐2,4(3H,8H)‐dione with antidepressant‐ and anxiolytic‐like activities

Published in:

Chemical Biology & Drug Design, 2019, v. 93, n. 4, p. 511, doi. 10.1111/cbdd.13442

By:

Zagórska, Agnieszka;
Partyka, Anna;
Bucki, Adam;
Kołaczkowski, Marcin;
Jastrzębska‐Więsek, Magdalena;
Czopek, Anna;
Siwek, Agata;
Głuch‐Lutwin, Monika;
Bednarski, Marek;
Bajda, Marek;
Jończyk, Jakub;
Piska, Kamil;
Koczurkiewicz, Paulina;
Wesołowska, Anna;
Pawłowski, Maciej

Publication type:

Article