Works by Jirgensons, Aigars

Results: 28

Spiropyran-Based Photoisomerizable α-Amino Acid for Membrane-Active Peptide Modification.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 22, p. 1, doi. 10.1002/chem.202400066

By:

Hrebonkin, Andrii;
Afonin, Sergii;
Nikitjuka, Anna;
Borysov, Oleksandr V.;
Leitis, Gundars;
Babii, Oleg;
Koniev, Serhii;
Lorig, Theo;
Grage, Stephan L.;
Nick, Peter;
Ulrich, Anne S.;
Jirgensons, Aigars;
Komarov, Igor V.

Publication type:

Article

Structure-based identification of salicylic acid derivatives as malarial threonyl tRNA-synthetase inhibitors.

Published in:

PLoS ONE, 2024, v. 19, n. 4, p. 1, doi. 10.1371/journal.pone.0296995

By:

Bobrovs, Raitis;
Bolsakova, Jekaterina;
Buitrago, Jhon Alexander Rodriguez;
Varaceva, Larisa;
Skvorcova, Marija;
Kanepe, Iveta;
Rudnickiha, Anastasija;
Parisini, Emilio;
Jirgensons, Aigars

Publication type:

Article

Azole‐based non‐peptidomimetic plasmepsin inhibitors.

Published in:

Archiv der Pharmazie, 2018, v. 351, n. 9, p. 1, doi. 10.1002/ardp.201800151

By:

Kinena, Linda;
Leitis, Gundars;
Kanepe‐Lapsa, Iveta;
Bobrovs, Raitis;
Jaudzems, Kristaps;
Ozola, Vita;
Suna, Edgars;
Jirgensons, Aigars

Publication type:

Article

3-(Adenosylthio)benzoic Acid Derivatives as SARS-CoV-2 Nsp14 Methyltransferase Inhibitors.

Published in:

Molecules, 2023, v. 28, n. 2, p. 768, doi. 10.3390/molecules28020768

By:

Bobileva, Olga;
Bobrovs, Raitis;
Sirma, Evelina Elva;
Kanepe, Iveta;
Bula, Anna L.;
Patetko, Liene;
Ramata-Stunda, Anna;
Grinberga, Solveiga;
Jirgensons, Aigars;
Jaudzems, Kristaps

Publication type:

Article

N-Sulfonylcarboxamide as an Oxidizing Directing Group for Ruthenium-Catalyzed C-H Activation/Annulation.

Published in:

European Journal of Organic Chemistry, 2017, v. 2017, n. 13, p. 1773, doi. 10.1002/ejoc.201601582

By:

Petrova, Elina;
Rasina, Dace;
Jirgensons, Aigars

Publication type:

Article

Synthesis of α-Ethynyl Glycines.

Published in:

European Journal of Organic Chemistry, 2016, v. 2016, n. 27, p. 4591, doi. 10.1002/ejoc.201600253

By:

Bolsakova, Jekaterina;
Jirgensons, Aigars

Publication type:

Article

Synthesis of Alkynyl-Glycinols by Lewis Acid Catalyzed Propargylic Substitution of Bis-Imidates.

Published in:

European Journal of Organic Chemistry, 2015, v. 2015, n. 31, p. 6900, doi. 10.1002/ejoc.201500937

By:

Sirotkina, Jekaterina;
Grigorjeva, Liene;
Jirgensons, Aigars

Publication type:

Article

Synthesis of Cyclic N-Tosyliminocarbonates by Lewis Acid Catalyzed Allylic Substitution of Trichloroacetimidates.

Published in:

European Journal of Organic Chemistry, 2012, v. 2012, n. 27, p. 5307, doi. 10.1002/ejoc.201200378

By:

Grigorjeva, Liene;
Jirgensons, Aigars

Publication type:

Article

Structural Basis for Inhibition of the SARS‐CoV‐2 nsp16 by Substrate‐Based Dual Site Inhibitors.

Published in:

ChemMedChem, 2024, v. 19, n. 24, p. 1, doi. 10.1002/cmdc.202400618

By:

Kalnins, Gints;
Rudusa, Laura;
Bula, Anna L.;
Zelencova‐Gopejenko, Diana;
Bobileva, Olga;
Sisovs, Mihails;
Tars, Kaspars;
Jirgensons, Aigars;
Jaudzems, Kristaps;
Bobrovs, Raitis

Publication type:

Article

Synthesis of Hydroxamic Acids by Activation of Carboxylic Acids with N,N'-Carbonyldiimidazole: Exploring the Efficiency of the Method.

Published in:

Synthetic Communications, 2010, v. 40, n. 6, p. 927, doi. 10.1080/00397910903026723

By:

Usachova, Natalija;
Leitis, Gundars;
Jirgensons, Aigars;
Kalvinsh, Ivars

Publication type:

Article

Torii‐Type Electrosynthesis of α,β‐Unsaturated Esters from Furfurylated Ethylene Glycols and Amino Alcohols.

Published in:

European Journal of Organic Chemistry, 2021, v. 2021, n. 29, p. 4224, doi. 10.1002/ejoc.202100605

By:

Darzina, Madara;
Lielpetere, Anna;
Jirgensons, Aigars

Publication type:

Article

Friedel–Crafts Alkylation with Carbenium Ions Generated by Electrochemical Oxidation of Stannylmethyl Ethers.

Published in:

European Journal of Organic Chemistry, 2020, v. 2020, n. 29, p. 4510, doi. 10.1002/ejoc.202000568

By:

Lielpetere, Anna;
Jirgensons, Aigars

Publication type:

Article

Virtual Screening for Selective Allosteric mGluR1 Antagonists and Structure-Activity Relationship Investigations for Coumarine Derivatives.

Published in:

ChemMedChem, 2007, v. 2, n. 12, p. 1763, doi. 10.1002/cmdc.200700151

By:

Noeske, Tobias;
Jirgensons, Aigars;
Starchenkovs, Igors;
Renner, Steffen;
Jaunzeme, Ieva;
Trifanova, Dina;
Hechenberger, Mirko;
Bauer, Tanja;
Kauss, Valerjans;
Parsons, Christopher G.;
Schneider, Gisbert;
Weil, Tanja

Publication type:

Article

Effect of novel furan‐based ester reactive diluent on structure and properties of UV‐crosslinked acrylated rapeseed oil.

Published in:

Journal of Polymer Science, 2023, v. 61, n. 24, p. 3318, doi. 10.1002/pol.20230451

By:

Briede, Sabine;
Platnieks, Oskars;
Darzina, Madara;
Jirgensons, Aigars;
Gaidukovs, Sergejs

Publication type:

Article

Discovery of SARS-CoV-2 Nsp14 and Nsp16 Methyltransferase Inhibitors by High-Throughput Virtual Screening.

Published in:

Pharmaceuticals (14248247), 2021, v. 14, n. 12, p. 1243, doi. 10.3390/ph14121243

By:

Bobrovs, Raitis;
Kanepe, Iveta;
Narvaiss, Nauris;
Patetko, Liene;
Kalnins, Gints;
Sisovs, Mihails;
Bula, Anna L.;
Grinberga, Solveiga;
Boroduskis, Martins;
Ramata-Stunda, Anna;
Rostoks, Nils;
Jirgensons, Aigars;
Tars, Kaspars;
Jaudzems, Kristaps

Publication type:

Article

Refining the structure−activity relationships of 2-phenylcyclopropane carboxylic acids as inhibitors of O-acetylserine sulfhydrylase isoforms.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 31, doi. 10.1080/14756366.2018.1518959

By:

Magalhães, Joana;
Franko, Nina;
Annunziato, Giannamaria;
Pieroni, Marco;
Benoni, Roberto;
Nikitjuka, Anna;
Mozzarelli, Andrea;
Bettati, Stefano;
Karawajczyk, Anna;
Jirgensons, Aigars;
Campanini, Barbara;
Costantino, Gabriele

Publication type:

Article

Discovery of novel fragments inhibiting O-acetylserine sulphhydrylase by combining scaffold hopping and ligand-based drug design.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2018, v. 33, n. 1, p. 1444, doi. 10.1080/14756366.2018.1512596

By:

Magalhães, Joana;
Franko, Nina;
Annunziato, Giannamaria;
Welch, Martin;
Dolan, Stephen K.;
Bruno, Agostino;
Mozzarelli, Andrea;
Armao, Stefano;
Jirgensons, Aigars;
Pieroni, Marco;
Costantino, Gabriele;
Campanini, Barbara

Publication type:

Article

Inhibition of O-acetylserine sulfhydrylase by fluoroalanine derivatives.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2018, v. 33, n. 1, p. 1343, doi. 10.1080/14756366.2018.1504040

By:

Franko, Nina;
Grammatoglou, Konstantinos;
Campanini, Barbara;
Costantino, Gabriele;
Jirgensons, Aigars;
Mozzarelli, Andrea

Publication type:

Article

Crystal structure of Plasmodium falciparum proplasmepsin IV: the plasticity of proplasmepsins.

Published in:

Acta Crystallographica: Section F, Structural Biology Communications, 2016, v. 72, n. 9, p. 659, doi. 10.1107/S2053230X16011663

By:

Recacha, Rosario;
Jaudzems, Kristaps;
Akopjana, Inara;
Jirgensons, Aigars;
Tars, Kaspars

Publication type:

Article

Structures of plasmepsin II from Plasmodium falciparum in complex with two hydroxyethylamine-based inhibitors.

Published in:

Acta Crystallographica: Section F, Structural Biology Communications, 2015, v. 71, n. 12, p. 1531, doi. 10.1107/S2053230X15022049

By:

Recacha, Rosario;
Leitans, Janis;
Akopjana, Inara;
Aprupe, Lilija;
Trapencieris, Peteris;
Jaudzems, Kristaps;
Jirgensons, Aigars;
Tars, Kaspars

Publication type:

Article

Synthesis of 2-arylquinazolines by Chan–Evans–Lam coupling of 2-formylphenylboronic acids with amidines.

Published in:

Chemistry of Heterocyclic Compounds, 2024, v. 60, n. 3/4, p. 169, doi. 10.1007/s10593-024-03314-2

By:

Solomin, Vitalii V.;
Zaharova, Darija;
Jirgensons, Aigars

Publication type:

Article

Synthesis and SAR of phenylazoles, active against Staphylococcus aureus Newman.

Published in:

Chemistry of Heterocyclic Compounds, 2022, v. 58, n. 12, p. 737, doi. 10.1007/s10593-023-03151-9

By:

Solomin, Vitalii V.;
Ciruelos, Blanca Fernandez;
Velikova, Nadya;
Wells, Jerry;
Albanese, Marco;
Adhav, Anmol;
Jirgensons, Aigars

Publication type:

Article

Intramolecular Friedel–Crafts alkylation by electrochemical carbenium ion generation.

Published in:

Chemistry of Heterocyclic Compounds, 2022, v. 58, n. 12, p. 732, doi. 10.1007/s10593-023-03150-w

By:

Lielpētere, Anna;
Šilaks, Artūrs;
Jirgensons, Aigars

Publication type:

Article

Synthesis of 2-aminopyridopyrimidinones and their plasmepsin I, II, IV inhibition potency.

Published in:

Chemistry of Heterocyclic Compounds, 2020, v. 56, n. 6, p. 786, doi. 10.1007/s10593-020-02731-3

By:

Rasina, Dace;
Stakanovs, Georgijs;
Kanepe-Lapsa, Iveta;
Bobrovs, Raitis;
Jaudzems, Kristaps;
Jirgensons, Aigars

Publication type:

Article

The Ritter reaction for the synthesis of heterocycles.

Published in:

Chemistry of Heterocyclic Compounds, 2017, v. 53, n. 11, p. 1167, doi. 10.1007/s10593-018-2189-y

By:

Bolsakova, Jekaterina;
Jirgensons, Aigars

Publication type:

Article

1-Amino-1-hydroxymethylcyclobutane derivatives via intramolecular amination of nonclassical cyclopropylmethyl cation.

Published in:

Chemistry of Heterocyclic Compounds, 2017, v. 53, n. 9, p. 989, doi. 10.1007/s10593-017-2162-1

By:

Skvorcova, Marija;
Grigorjeva, Liene;
Jirgensons, Aigars

Publication type:

Article

Synthesis and biological evaluation of aziridin-1-yl oxime-based vorinostat analogs as anticancer agents.

Published in:

Chemistry of Heterocyclic Compounds, 2015, v. 51, n. 7, p. 647, doi. 10.1007/s10593-015-1752-z

By:

Nikitjuka, Anna;
Shestakova, Irina;
Romanchikova, Nadezhda;
Jirgensons, Aigars

Publication type:

Article

Lewis Acid Catalyzed Intramolecular Allylic Substitution of Bis(trichloroacetimidates): A Versatile Approach to Racemic Unsaturated Amino Acids.

Published in:

European Journal of Organic Chemistry, 2011, v. 2011, n. 13, p. 2421, doi. 10.1002/ejoc.201100060

By:

Grigorjeva, Liene;
Jirgensons, Aigars

Publication type:

Article