Works by Jinek, Martin

Results: 40

Structural mimicry in transcription regulation of human RNA polymerase II by the DNA helicase RECQL5.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 7, p. 892, doi. 10.1038/nsmb.2596

By:

Kassube, Susanne A;
Jinek, Martin;
Fang, Jie;
Tsutakawa, Susan;
Nogales, Eva

Publication type:

Article

An RNA-induced conformational change required for CRISPR RNA cleavage by the endoribonuclease Cse3.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 6, p. 680, doi. 10.1038/nsmb.2043

By:

Sashital, Dipali G.;
Jinek, Martin;
Doudna, Jennifer A.

Publication type:

Article

Structural insights into the human GW182-PABC interaction in microRNA-mediated deadenylation.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 2, p. 238, doi. 10.1038/nsmb.1768

By:

Jinek, Martin;
Fabian, Marc R.;
Coyle, Scott M.;
Sonenberg, Nahum;
Doudna, Jennifer A.

Publication type:

Article

Structural insights into the Notch-modifying glycosyltransferase Fringe.

Published in:

Nature Structural & Molecular Biology, 2006, v. 13, n. 10, p. 945, doi. 10.1038/nsmb1144

By:

Jinek, Martin;
Chen, Ya-Wen;
Clausen, Henrik;
Cohen, Stephen M.;
Conti, Elena

Publication type:

Article

Data-collection strategy for challenging native SAD phasing.

Published in:

Acta Crystallographica: Section D, Structural Biology, 2016, v. 72, n. 3, p. 421, doi. 10.1107/S2059798315024110

By:

Olieric, Vincent;
Weinert, Tobias;
Finke, Aaron D.;
Anders, Carolin;
Li, Dianfan;
Olieric, Natacha;
Borca, Camelia N.;
Steinmetz, Michel O.;
Caffrey, Martin;
Jinek, Martin;
Wang, Meitian

Publication type:

Article

Molecular architecture of the human tRNA ligase complex.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.71656

By:

Kroupova, Alena;
Ackle, Fabian;
AsanoviÄ?, Igor;
Weitzer, Stefan;
Boneberg, Franziska M.;
Faini, Marco;
Leitner, Alexander;
Chui, Alessia;
Aebersold, Ruedi;
Martinez, Javier;
Jinek, Martin

Publication type:

Article

Molecular architecture of LSM14 interactions involved in the assembly of mRNA silencing complexes.

Published in:

EMBO Journal, 2018, v. 37, n. 7, p. 1, doi. 10.15252/embj.201797869

By:

Brandmann, Tobias;
Fakim, Hana;
Padamsi, Zoya;
Youn, Ji‐Young;
Gingras, Anne‐Claude;
Fabian, Marc R.;
Jinek, Martin

Publication type:

Article

The superhelical TPR-repeat domain of O-linked GlcNAc transferase exhibits structural similarities to importina.

Published in:

Nature Structural & Molecular Biology, 2004, v. 11, n. 10, p. 1001, doi. 10.1038/nsmb833

By:

Jínek, Martin;
Rehwinkel, Jan;
Lazarus, Brooke D;
Izaurralde, Elisa;
Hanover, John A;
Conti, Elena

Publication type:

Article

Cover Image, Volume 9, Issue 5.

Published in:

Wiley Interdisciplinary Reviews: RNA, 2018, v. 9, n. 5, p. 1, doi. 10.1002/wrna.1505

By:

Swarts, Daan C.;
Jinek, Martin

Publication type:

Article

Cas9 versus Cas12a/Cpf1: Structure–function comparisons and implications for genome editing.

Published in:

Wiley Interdisciplinary Reviews: RNA, 2018, v. 9, n. 5, p. 1, doi. 10.1002/wrna.1481

By:

Swarts, Daan C.;
Jinek, Martin

Publication type:

Article

Gene editing of NCF1 loci is associated with homologous recombination and chromosomal rearrangements.

Published in:

Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-06959-z

By:

Raimondi, Federica;
Siow, Kah Mun;
Wrona, Dominik;
Fuster-García, Carla;
Pastukhov, Oleksandr;
Schmitz, Michael;
Bargsten, Katja;
Kissling, Lucas;
Swarts, Daan C.;
Andrieux, Geoffroy;
Cathomen, Toni;
Modlich, Ute;
Jinek, Martin;
Siler, Ulrich;
Reichenbach, Janine

Publication type:

Article

Hakai is required for stabilization of core components of the m6A mRNA methylation machinery.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23892-5

By:

Bawankar, Praveen;
Lence, Tina;
Paolantoni, Chiara;
Haussmann, Irmgard U.;
Kazlauskiene, Migle;
Jacob, Dominik;
Heidelberger, Jan B.;
Richter, Florian M.;
Nallasivan, Mohanakarthik P.;
Morin, Violeta;
Kreim, Nastasja;
Beli, Petra;
Helm, Mark;
Jinek, Martin;
Soller, Matthias;
Roignant, Jean-Yves

Publication type:

Article

Fip1 is a multivalent interaction scaffold for processing factors in human mRNA 3' end biogenesis.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.80332

By:

Muckenfuss, Lena Maria;
Herranz, Anabel Carmen Migenda;
Boneberg, Franziska Maria;
Clerici, Marcello;
Jinek, Martin

Publication type:

Article

Fip1 is a multivalent interaction scaffold for processing factors in human mRNA 3′ end biogenesis.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.80332

By:

Muckenfuss, Lena Maria;
Migenda Herranz, Anabel Carmen;
Boneberg, Franziska Maria;
Clerici, Marcello;
Jinek, Martin

Publication type:

Article

Structural basis of TnsC oligomerization and transposase recruitment in type I-B CRISPR-associated transposons.

Published in:

Nucleic Acids Research, 2025, v. 53, n. 5, p. 1, doi. 10.1093/nar/gkaf149

By:

Finocchio, Giada;
Querques, Irma;
Chanez, Christelle;
Speichert, Katarzyna J;
Jinek, Martin

Publication type:

Article

Mechanistic determinants and dynamics of cA6 synthesis in type III CRISPR-Cas effector complexes.

Published in:

Nucleic Acids Research, 2025, v. 53, n. 2, p. 1, doi. 10.1093/nar/gkae1277

By:

Jungfer, Kenny;
Moravčík, Štefan;
Garcia-Doval, Carmela;
Knörlein, Anna;
Hall, Jonathan;
Jinek, Martin

Publication type:

Article

Target DNA-dependent activation mechanism of the prokaryotic immune system SPARTA.

Published in:

Nucleic Acids Research, 2024, v. 52, n. 4, p. 2012, doi. 10.1093/nar/gkad1248

By:

Finocchio, Giada;
Koopal, Balwina;
Potocnik, Ana;
Heijstek, Clint;
Westphal, Adrie H;
Jinek, Martin;
Swarts, Daan C

Publication type:

Article

Substrate selectivity and catalytic activation of the type III CRISPR ancillary nuclease Can2.

Published in:

Nucleic Acids Research, 2024, v. 52, n. 1, p. 462, doi. 10.1093/nar/gkad1102

By:

Jungfer, Kenny;
Sigg, Annina;
Jinek, Martin

Publication type:

Article

DNA-guided DNA cleavage at moderate temperatures by Clostridium butyricum Argonaute.

Published in:

Nucleic Acids Research, 2019, v. 47, n. 11, p. 5809, doi. 10.1093/nar/gkz306

By:

Hegge, Jorrit W;
Swarts, Daan C;
Chandradoss, Stanley D;
Cui, Tao Ju;
Kneppers, Jeroen;
Jinek, Martin;
Joo, Chirlmin;
van der Oost, John

Publication type:

Article

Structural basis for acceptor RNA substrate selectivity of the 3′ terminal uridylyl transferase Tailor.

Published in:

Nucleic Acids Research, 2019, v. 47, n. 2, p. 1030, doi. 10.1093/nar/gky1164

By:

Kroupova, Alena;
Ivaşcu, Anastasia;
Reimão-Pinto, Madalena M;
Ameres, Stefan L;
Jinek, Martin

Publication type:

Article

Human MARF1 is an endoribonuclease that interacts with the DCP1:2 decapping complex and degrades target mRNAs.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 22, p. 12008, doi. 10.1093/nar/gky1011

By:

Nishimura, Tamiko;
Fakim, Hana;
Brandmann, Tobias;
Youn, Ji-Young;
Gingras, Anne-Claude;
Jinek, Martin;
Fabian, Marc R

Publication type:

Article

Bacteriophage DNA glucosylation impairs target DNA binding by type I and II but not by type V CRISPR-Cas effector complexes.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 2, p. 873, doi. 10.1093/nar/gkx1264

By:

Vlot, Marnix;
Houkes, Joep;
Lochs, Silke J A;
Swarts, Daan C;
Zheng, Peiyuan;
Kunne, Tim;
Mohanraju, Prarthana;
Anders, Carolin;
Jinek, Martin;
van der Oost, John

Publication type:

Article

Introducing gene deletions by mouse zygote electroporation of Cas12a/Cpf1.

Published in:

Transgenic Research, 2019, v. 28, n. 5/6, p. 525, doi. 10.1007/s11248-019-00168-9

By:

Dumeau, Charles-Etienne;
Monfort, Asun;
Kissling, Lucas;
Swarts, Daan C.;
Jinek, Martin;
Wutz, Anton

Publication type:

Article

Structures of the tRNA export factor in the nuclear and cytosolic states.

Published in:

Nature, 2009, v. 461, n. 7260, p. 60, doi. 10.1038/nature08394

By:

Cook, Atlanta G.;
Fukuhara, Noemi;
Jinek, Martin;
Conti, Elena

Publication type:

Article

A three-dimensional view of the molecular machinery of RNA interference.

Published in:

Nature, 2009, v. 457, n. 7228, p. 405, doi. 10.1038/nature07755

By:

Jinek, Martin;
Doudna, Jennifer A.

Publication type:

Article

Activation and self-inactivation mechanisms of the cyclic oligoadenylate-dependent CRISPR ribonuclease Csm6.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-15334-5

By:

Garcia-Doval, Carmela;
Schwede, Frank;
Berk, Christian;
Rostøl, Jakob T.;
Niewoehner, Ole;
Tejero, Oliver;
Hall, Jonathan;
Marraffini, Luciano A.;
Jinek, Martin

Publication type:

Article

HLTF disrupts Cas9-DNA post-cleavage complexes to allow DNA break processing.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-50080-y

By:

Reginato, Giordano;
Dello Stritto, Maria Rosaria;
Wang, Yanbo;
Hao, Jingzhou;
Pavani, Raphael;
Schmitz, Michael;
Halder, Swagata;
Morin, Vincent;
Cannavo, Elda;
Ceppi, Ilaria;
Braunshier, Stefan;
Acharya, Ananya;
Ropars, Virginie;
Charbonnier, Jean-Baptiste;
Jinek, Martin;
Nussenzweig, Andrè;
Ha, Taekjip;
Cejka, Petr

Publication type:

Article

RNA-guided RNA silencing by an Asgard archaeal Argonaute.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-49452-1

By:

Bastiaanssen, Carolien;
Bobadilla Ugarte, Pilar;
Kim, Kijun;
Finocchio, Giada;
Feng, Yanlei;
Anzelon, Todd A.;
Köstlbacher, Stephan;
Tamarit, Daniel;
Ettema, Thijs J. G.;
Jinek, Martin;
MacRae, Ian J.;
Joo, Chirlmin;
Swarts, Daan C.;
Wu, Fabai

Publication type:

Article

Enhancing prime editor activity by directed protein evolution in yeast.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46107-z

By:

Weber, Yanik;
Böck, Desirée;
Ivașcu, Anastasia;
Mathis, Nicolas;
Rothgangl, Tanja;
Ioannidi, Eleonora I.;
Blaudt, Alex C.;
Tidecks, Lisa;
Vadovics, Máté;
Muramatsu, Hiromi;
Reichmuth, Andreas;
Marquart, Kim F.;
Kissling, Lucas;
Pardi, Norbert;
Jinek, Martin;
Schwank, Gerald

Publication type:

Article

An alpha-helical lid guides the target DNA toward catalysis in CRISPR-Cas12a.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-45762-6

By:

Saha, Aakash;
Ahsan, Mohd;
Arantes, Pablo R.;
Schmitz, Michael;
Chanez, Christelle;
Jinek, Martin;
Palermo, Giulia

Publication type:

Article

An alpha-helical lid guides the target DNA toward catalysis in CRISPR-Cas12a.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-45762-6

By:

Saha, Aakash;
Ahsan, Mohd;
Arantes, Pablo R.;
Schmitz, Michael;
Chanez, Christelle;
Jinek, Martin;
Palermo, Giulia

Publication type:

Article

PAM-flexible genome editing with an engineered chimeric Cas9.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-41829-y

By:

Zhao, Lin;
Koseki, Sabrina R. T.;
Silverstein, Rachel A.;
Amrani, Nadia;
Peng, Christina;
Kramme, Christian;
Savic, Natasha;
Pacesa, Martin;
Rodríguez, Tomás C.;
Stan, Teodora;
Tysinger, Emma;
Hong, Lauren;
Yudistyra, Vivian;
Ponnapati, Manvitha R.;
Jacobson, Joseph M.;
Church, George M.;
Jakimo, Noah;
Truant, Ray;
Jinek, Martin;
Kleinstiver, Benjamin P.

Publication type:

Article

Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease.

Published in:

Nature, 2014, v. 513, n. 7519, p. 569, doi. 10.1038/nature13579

By:

Anders, Carolin;
Niewoehner, Ole;
Duerst, Alessia;
Jinek, Martin

Publication type:

Article

DNA interrogation by the CRISPR RNA-guided endonuclease Cas9.

Published in:

Nature, 2014, v. 507, n. 7490, p. 62, doi. 10.1038/nature13011

By:

Sternberg, Samuel H.;
Redding, Sy;
Jinek, Martin;
Greene, Eric C.;
Doudna, Jennifer A.

Publication type:

Article

Structural insights into the assembly and polyA signal recognition mechanism of the human CPSF complex.

Published in:

eLife, 2017, p. 1, doi. 10.7554/eLife.33111

By:

Clerici, Marcello;
Faini, Marco;
Aebersold, Ruedi;
Jinek, Martin

Publication type:

Article

Structural insights into the molecular mechanism of the m<sup>6</sup>A writer complex.

Published in:

eLife, 2016, p. 1, doi. 10.7554/eLife.18434

By:

Śledź, Paweł;
Jinek, Martin

Publication type:

Article

Evolution of CRISPR RNA recognition and processing by Cas6 endonucleases.

Published in:

Nucleic Acids Research, 2014, v. 42, n. 2, p. 1341, doi. 10.1093/nar/gkt922

By:

Niewoehner, Ole;
Jinek, Martin;
Doudna, Jennifer A.

Publication type:

Article

CrispRVariants charts the mutation spectrum of genome engineering experiments.

Published in:

Nature Biotechnology, 2016, v. 34, n. 7, p. 701, doi. 10.1038/nbt.3628

By:

Lindsay, Helen;
Burger, Alexa;
Biyong, Berthin;
Felker, Anastasia;
Hess, Christopher;
Zaugg, Jonas;
Chiavacci, Elena;
Anders, Carolin;
Jinek, Martin;
Mosimann, Christian;
Robinson, Mark D

Publication type:

Article

Crystal structure of the C-terminal 2′,5′-phosphodiesterase domain of group a rotavirus protein VP3.

Published in:

Proteins, 2015, v. 83, n. 5, p. 997, doi. 10.1002/prot.24794

By:

Brandmann, Tobias;
Jinek, Martin

Publication type:

Article

Molecular basis for cytoplasmic RNA surveillance by uridylation-triggered decay in Drosophila.

Published in:

EMBO Journal, 2016, v. 35, n. 22, p. 2417, doi. 10.15252/embj.201695164

By:

Reimão‐Pinto, Madalena M;
Manzenreither, Raphael A;
Burkard, Thomas R;
Sledz, Pawel;
Jinek, Martin;
Mechtler, Karl;
Ameres, Stefan L

Publication type:

Article