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AAV8-vectored suprachoroidal gene transfer produces widespread ocular transgene expression.
Published in:
2019
By:
- Kun Ding;
- Jikui Shen;
- Hafiz, Zibran;
- Hackett, Sean F.;
- Lima e Silva, Raquel;
- Khan, Mahmood;
- Lorenc, Valeria E.;
- Daiqin Chen;
- Chadha, Rishi;
- Minie Zhang;
- Van Everen, Sherri;
- Buss, Nicholas;
- Fiscella, Michele;
- Danos, Olivier;
- Campochiaro, Peter A.;
- Ding, Kun;
- Shen, Jikui;
- Silva, Raquel Lima E;
- Chen, Daiqin;
- Zhang, Minie
Publication type:
journal article
Targeting VE-PTP activates TIE2 and stabilizes the ocular vasculature.
Published in:
Journal of Clinical Investigation, 2014, v. 124, n. 10, p. 4564, doi. 10.1172/JCI74527
By:
- Jikui Shen;
- Frye, Maike;
- Lee, Bonnie L.;
- Reinardy, Jessica L.;
- McClung, Joseph M.;
- Kun Ding;
- Masashi Kojima;
- Huiming Xia;
- Seidel, Christopher;
- Lima e. Silva, Raquel;
- Aling Dong;
- Hackett, Sean F.;
- Jiangxia Wang;
- Howard, Brian W.;
- Vestweber, Dietmar;
- Kontos, Christopher D.;
- Peters, Kevin G.;
- Campochiaro, Peter A.
Publication type:
Article
Cover Image, Volume 93, Number 12, December 2021.
Published in:
Journal of Medical Virology, 2021, v. 93, n. 12, p. i, doi. 10.1002/jmv.27388
By:
- Fang, Shuyi;
- Liu, Sheng;
- Shen, Jikui;
- Lu, Alex Z;
- Wang, Audrey K. Y.;
- Zhang, Yucheng;
- Li, Kailing;
- Liu, Juli;
- Yang, Lei;
- Hu, Chang‐Deng;
- Wan, Jun
Publication type:
Article
Updated SARS‐CoV‐2 single nucleotide variants and mortality association.
Published in:
Journal of Medical Virology, 2021, v. 93, n. 12, p. 6525, doi. 10.1002/jmv.27191
By:
- Fang, Shuyi;
- Liu, Sheng;
- Shen, Jikui;
- Lu, Alex Z;
- Wang, Audrey K. Y.;
- Zhang, Yucheng;
- Li, Kailing;
- Liu, Juli;
- Yang, Lei;
- Hu, Chang‐Deng;
- Wan, Jun
Publication type:
Article
Structure-Guided Molecular Engineering of a Vascular Endothelial Growth Factor Antagonist to Treat Retinal Diseases.
Published in:
Cellular & Molecular Bioengineering, 2020, v. 13, n. 5, p. 405, doi. 10.1007/s12195-020-00641-0
By:
- Kureshi, Rakeeb;
- Zhu, Angela;
- Shen, Jikui;
- Tzeng, Stephany Y.;
- Astrab, Leilani R.;
- Sargunas, Paul R.;
- Green, Jordan J.;
- Campochiaro, Peter A.;
- Spangler, Jamie B.
Publication type:
Article
Improvement and Optimization of Standards for a Preclinical Animal Test Model of Laser Induced Choroidal Neovascularization.
Published in:
PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0094743
By:
- Zhu, Yanji;
- Lu, Qing;
- Shen, Jikui;
- Zhang, Ling;
- Gao, Yushuo;
- Shen, Xi;
- Xie, Bing
Publication type:
Article
Blockade of VEGFR1 and 2 Suppresses Pathological Angiogenesis and Vascular Leakage in the Eye.
Published in:
PLoS ONE, 2011, v. 6, n. 6, p. 1, doi. 10.1371/journal.pone.0021411
By:
- Hu Huang;
- Shen, Jikui;
- Vinores, Stanley A.
Publication type:
Article
En masse nascent transcription analysis to elucidate regulatory transcription factors.
Published in:
Nucleic Acids Research, 2006, v. 34, n. 5, p. 1492, doi. 10.1093/nar/gkj510
By:
- Fan, Jinshui;
- Zhan, Ming;
- Shen, Jikui;
- Martindale, Jennifer L.;
- Yang, Xiaoling;
- Kawai, Tomoko;
- Gorospe, Myriam
Publication type:
Article
Flt3 Regulation in the Mononuclear Phagocyte System Promotes Ocular Neovascularization.
Published in:
Journal of Ophthalmology, 2018, p. 1, doi. 10.1155/2018/2518568
By:
- Gao, Yushuo;
- Zhong, Yisheng;
- Zhu, Yanji;
- Demetriades, Anna M.;
- Cai, Yujuan;
- Shen, Jikui;
- Lu, Qing;
- Shen, Xi;
- Xie, Bing
Publication type:
Article
Digoxin inhibits retinal ischemia-induced HIF-1α expression and ocular neovascularization.
Published in:
FASEB Journal, 2010, v. 24, n. 6, p. 1759, doi. 10.1096/fj.09-145664
By:
- Yoshida, Tsunehiko;
- Zhang, Huafeng;
- Iwase, Takeshi;
- Jikui Shen;
- Semenza, Gregg L.;
- Campochiaro, Peter A.
Publication type:
Article
ATN-161 as an Integrin a5b1 Antagonist Depresses Ocular Neovascularization by Promoting New Vascular Endothelial Cell Apoptosis.
Published in:
Medical Science Monitor, 2018, v. 24, p. 5860, doi. 10.12659/MSM.907446
By:
- Ailing Sui;
- Yisheng Zhong;
- Demetriades, Anna M.;
- Jikui Shen;
- Ting Su;
- Yiyun Yao;
- Yushuo Gao;
- Yanji Zhu;
- Xi Shen;
- Bing Xie
Publication type:
Article
An Adam 15 amplification loop promotes vascular endothelial growth factor-induced ocular neovascularization.
Published in:
FASEB Journal, 2008, v. 22, n. 8, p. 2775, doi. 10.1096/fj.07-099283
By:
- Bing Xie;
- Jikui Shen;
- Dong, Aling;
- Swaim, Mara;
- Hackett, Sean F.;
- Wyder, Lorenza;
- Worpenberg, Susanne;
- Barbieri, Samuel;
- Campochiaro, Peter A.
Publication type:
Article
The SDF-1/CXCR4 ligand/receptor pair is an important contributor to several types of ocular neovascularization.
Published in:
FASEB Journal, 2007, v. 21, n. 12, p. 3219, doi. 10.1096/fj.06-7359com
By:
- Silva, Raquel Lima;
- Jikui Shen;
- Hackett, Sean F.;
- Shu Kachi;
- Akiyama, Hideo;
- Katsuji Kiuchi;
- Yokoi, Katsutoshi;
- Hatara, Maria C.;
- Lauer, Thomas;
- Aslam, Sadia;
- Yuan Yuan Gong;
- Wei-Hong Xiao;
- Naw Htee Khu;
- Thut, Catherine;
- Campochiaro, Peter A.
Publication type:
Article
Vasohibin is up-regulated by VEGF in the retina and suppresses VEGF receptor 2 and retinal neovascularization.
Published in:
FASEB Journal, 2006, v. 20, n. 6, p. 723, doi. 10.1096/fj.05-5046fje
By:
- JiKui Shen;
- XiaoRu Yang;
- Wei-Hong Xiao;
- Hackett, Sean F.;
- Yasufumi Sato;
- Campochiaro, Peter A.
Publication type:
Article
Different effects of angiopoietin-2 in different vascular beds: new vessels are most sensitive.
Published in:
FASEB Journal, 2005, v. 19, n. 8, p. 963, doi. 10.1096/fj.04-2209fje
By:
- Oshima, Yuji;
- Oshima, Sachiko;
- Nambu, Hiroyuki;
- Kachi, Shu;
- Takahashi, Kyoichi;
- Umeda, Naoyasu;
- Shen, JiKui;
- Dong, Aling;
- Apte, Rajendra S.;
- Duh, Elia;
- Hackett, Sean F.;
- Okoye, Godwin;
- Ishibashi, Kazuki;
- Handa, James;
- Melia, Michele;
- Wiegand, Stanley;
- Yancopoulos, George;
- Zack, Donald J.;
- Campochiaro, Peter A.
Publication type:
Article
Interleukin-18 Has Antipermeablity and Antiangiogenic Activities in the Eye: Reciprocal Suppression With VEGF.
Published in:
2014
By:
- Shen, Jikui;
- Choy, David F.;
- Yoshida, Tsunehiko;
- Iwase, Takeshi;
- Hafiz, Gulnar;
- Xie, Bing;
- Hackett, Sean F.;
- Arron, Joseph R.;
- Campochiaro, Peter A.
Publication type:
Editorial
Agents that bind annexin A2 suppress ocular neovascularization.
Published in:
Journal of Cellular Physiology, 2010, v. 225, n. 3, p. 855, doi. 10.1002/jcp.22296
By:
- SILVA, RAQUEL LIMA E;
- JIKUI SHEN;
- YUAN YUAN GONG;
- SEIDEL, CHRISTOPHER P.;
- HACKETT, SEAN F.;
- KESAVAN, KAMALA;
- JACOBY, DOUGLAS B.;
- CAMPOCHIARO, PETER A.
Publication type:
Article
Oxidative stress promotes ocular neovascularization.
Published in:
Journal of Cellular Physiology, 2009, v. 219, n. 3, p. 544, doi. 10.1002/jcp.21698
By:
- DONG, ALING;
- BING XIE;
- JIKUI SHEN;
- YOSHIDA, TSUNEHIKO;
- YOKOI, KATSUTOSHI;
- HACKETT, SEAN F.;
- CAMPOCHIARO, PETER A.
Publication type:
Article
Blockade of sphingosine-1-phosphate reduces macrophage influx and retinal and choroidal neovascularization.
Published in:
Journal of Cellular Physiology, 2009, v. 218, n. 1, p. 192, doi. 10.1002/jcp.21588
By:
- Xie, Bing;
- Shen, Jikui;
- Dong, Aling;
- Rashid, Aymen;
- Stoller, Glenn;
- Campochiaro, Peter A.
Publication type:
Article
Superoxide dismutase 1 protects retinal cells from oxidative damage<FNR></FNR><FN>Peter A. Campochiaro is the George S. and Dolores Dore Eccles Professor of Ophthalmology. </FN>.
Published in:
Journal of Cellular Physiology, 2006, v. 208, n. 3, p. 516, doi. 10.1002/jcp.20683
By:
- Aling Dong;
- Jikui Shen;
- Krause, Melissa;
- Akiyama, Hideo;
- Hackett, Sean F.;
- Hong Lai, Campochiaro
Publication type:
Article
Recombinant non-collagenous domain of α2(IV) collagen causes involution of choroidal neovascularization by inducing apoptosis.
Published in:
Journal of Cellular Physiology, 2006, v. 208, n. 1, p. 161, doi. 10.1002/jcp.20645
By:
- E Silva, Raquel Lima;
- Kachi, Shu;
- Akiyama, Hideo;
- Jikui Shen;
- Aslam, Sadia;
- Yuan Yuan Gong;
- Naw Htee Khu;
- Hatara, Maria C.;
- Boutaud, Ariel;
- Peterson, Robert;
- Campochiaro, Peter A.
Publication type:
Article
Implication of the hypoxia response element of the vegf promoter in mouse models of retinal and choroidal neovascularization, but not retinal vascular development.
Published in:
Journal of Cellular Physiology, 2006, v. 206, n. 3, p. 749, doi. 10.1002/jcp.20525
By:
- Vinores, Stanley A.;
- Wei-Hong Xiao;
- Aslam, Sadia;
- Jikui Shen;
- Oshima, Yuji;
- Nambu, Hiroyuki;
- Hansheng Liu;
- Carmeliet, Peter;
- Campochiaro, Peter A.
Publication type:
Article
Oxidative damage is a potential cause of cone cell death in retinitis pigmentosa.
Published in:
Journal of Cellular Physiology, 2005, v. 203, n. 3, p. 457, doi. 10.1002/jcp.20346
By:
- JiKui Shen;
- Xiaoru Yang;
- Aling Dong;
- Robert M. Petters;
- You-Wei Peng;
- Fulton Wong;
- Peter A. Campochiaro
Publication type:
Article
Increased Expression of Catalase and Superoxide Dismutase 2 Reduces Cone Cell Death in Retinitis Pigmentosa.
Published in:
Molecular Therapy, 2009, v. 17, n. 5, p. 778, doi. 10.1038/mt.2009.47
By:
- Usui, Shinichi;
- Komeima, Keiichi;
- Sun Young Lee;
- Young-Joon Jo;
- Shinji Ueno;
- Rogers, Brian S.;
- Zhihao Wu;
- Jikui Shen;
- Lili Lu;
- Oveson, Brian C.;
- Rabinovitch, Peter S.;
- Campochiaro, Peter A.
Publication type:
Article
MicroRNAs Regulate Ocular Neovascularization.
Published in:
Molecular Therapy, 2008, v. 16, n. 7, p. 1208, doi. 10.1038/mt.2008.104
By:
- JiKui Shen;
- Xiaoru Yang;
- Bing Xie;
- Yangjian Chen;
- Swaim, Mara;
- Hackett, Sean F.;
- Campochiaro, Peter A.
Publication type:
Article
Vegf or EphA2 Antisense Polyamide-nucleic acids; Vascular Localization and Suppression of Retinal Neovascularization.
Published in:
Molecular Therapy, 2007, v. 15, n. 11, p. 1924, doi. 10.1038/sj.mt.6300276
By:
- Jikui Shen;
- Bing Xie;
- Hatara, Christina M.;
- Hackett, Sean F.;
- Campochiaro, Peter A.
Publication type:
Article
Genetic Spectrum and Distinct Evolution Patterns of SARS-CoV-2.
Published in:
Frontiers in Microbiology, 2020, v. 11, p. N.PAG, doi. 10.3389/fmicb.2020.593548
By:
- Liu, Sheng;
- Shen, Jikui;
- Fang, Shuyi;
- Li, Kailing;
- Liu, Juli;
- Yang, Lei;
- Hu, Chang-Deng;
- Wan, Jun
Publication type:
Article
GESS: a database of global evaluation of SARS-CoV-2/hCoV-19 sequences.
Published in:
Nucleic Acids Research, 2021, v. 49, n. D1, p. D706, doi. 10.1093/nar/gkaa808
By:
- Fang, Shuyi;
- Li, Kailing;
- Shen, Jikui;
- Liu, Sheng;
- Liu, Juli;
- Yang, Lei;
- Hu, Chang-Deng;
- Wan, Jun
Publication type:
Article
The HIF-1 antagonist acriflavine: visualization in retina and suppression of ocular neovascularization.
Published in:
Journal of Molecular Medicine, 2017, v. 95, n. 4, p. 417, doi. 10.1007/s00109-016-1498-9
By:
- Zeng, Mingbing;
- Shen, Jikui;
- Liu, Yuanyuan;
- Lu, Lucy;
- Ding, Kun;
- Fortmann, Seth;
- Khan, Mahmood;
- Wang, Jiangxia;
- Hackett, Sean;
- Semenza, Gregg;
- Campochiaro, Peter
Publication type:
Article
Increased expression of glial cell line-derived neurotrophic factor protects against oxidative damage-induced retinal degeneration.
Published in:
Journal of Neurochemistry, 2007, v. 103, n. 3, p. 1041, doi. 10.1111/j.1471-4159.2007.04839.x
By:
- Aling Dong;
- JiKui Shen;
- Krause, Melissa;
- Hackett, Sean F.;
- Campochiaro, Peter A.
Publication type:
Article
Sustained treatment of retinal vascular diseases with self-aggregating sunitinib microparticles.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-14340-x
By:
- Tsujinaka, Hiroki;
- Fu, Jie;
- Shen, Jikui;
- Yu, Yun;
- Hafiz, Zibran;
- Kays, Joshua;
- McKenzie, David;
- Cardona, Delia;
- Culp, David;
- Peterson, Ward;
- Gilger, Brian C.;
- Crean, Christopher S.;
- Zhang, Jin-Zhong;
- Kanan, Yogita;
- Yu, Weiling;
- Cleland, Jeffrey L.;
- Yang, Ming;
- Hanes, Justin;
- Campochiaro, Peter A.
Publication type:
Article

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