Works by Jiang, Hualiang
Results: 202
A New Assay Based on Fluorescence Resonance Energy Transfer to Determine the Binding Affinity of Bcl-x[subL] Inhibitors.
- Published in:
- Bioscience, Biotechnology & Biochemistry, 2008, v. 72, n. 7, p. 1936, doi. 10.1271/bbb.70735
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- Publication type:
- Article
Insights into divalent cation regulation and G<sub>13</sub>-coupling of orphan receptor GPR35.
- Published in:
- Cell Discovery, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41421-022-00499-8
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- Publication type:
- Article
Glycan Epitopes and Potential Glycoside Antagonists of DC-SIGN Involved in COVID-19: In Silico Study.
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- Biomolecules (2218-273X), 2021, v. 11, n. 11, p. 1586, doi. 10.3390/biom11111586
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- Publication type:
- Article
Improving the Virtual Screening Ability of Target-Specific Scoring Functions Using Deep Learning Methods.
- Published in:
- Frontiers in Pharmacology, 2019, p. 1, doi. 10.3389/fphar.2019.00924
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- Publication type:
- Article
17-AAG synergizes with Belinostat to exhibit a negative effect on the proliferation and invasion of MDA-MB-231 breast cancer cells.
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- Oncology Reports, 2020, v. 43, n. 6, p. 1928, doi. 10.3892/or.2020.7563
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- Publication type:
- Article
The nucleocapsid protein of SARS coronavirus has a high binding affinity to the human cellular heterogeneous nuclear ribonucleoprotein A1
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- FEBS Letters, 2005, v. 579, n. 12, p. 2623, doi. 10.1016/j.febslet.2005.03.080
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- Publication type:
- Article
Arctigenin Effectively Ameliorates Memory Impairment in Alzheimer's Disease Model Mice Targeting Both β-Amyloid Production and Clearance.
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- Journal of Neuroscience, 2013, v. 33, n. 32, p. 13138, doi. 10.1523/JNEUROSCI.4790-12.2013
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- Publication type:
- Article
Bioactive conformational generation of small molecules: A comparative analysis between forcefield and multiple empirical criteria based methods.
- Published in:
- BMC Bioinformatics, 2010, v. 11, p. 545, doi. 10.1186/1471-2105-11-545
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- Publication type:
- Article
BSSF: a fingerprint based ultrafast binding site similarity search and function analysis server.
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- BMC Bioinformatics, 2010, v. 11, p. 1, doi. 10.1186/1471-2105-11-47
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- Publication type:
- Article
An effective docking strategy for virtual screening based on multi-objective optimization algorithm.
- Published in:
- BMC Bioinformatics, 2009, v. 10, p. 1, doi. 10.1186/1471-2105-10-58
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- Publication type:
- Article
Cyndi: a multi-objective evolution algorithm based method for bioactive molecular conformational generation.
- Published in:
- BMC Bioinformatics, 2009, v. 10, p. 1, doi. 10.1186/1471-2105-10-101
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- Publication type:
- Article
PDTD: a web-accessible protein database for drug target identification.
- Published in:
- BMC Bioinformatics, 2008, v. 9, p. 1, doi. 10.1186/1471-2105-9-104
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- Publication type:
- Article
Computational drug discovery.
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- Acta Pharmacologica Sinica, 2012, v. 33, n. 9, p. 1131, doi. 10.1038/aps.2012.109
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- Publication type:
- Article
Discovery of Benzylidene Derivatives as Potent Syk Inhibitors: Synthesis, SAR Analysis, and Biological Evaluation.
- Published in:
- Archiv der Pharmazie, 2015, v. 348, n. 7, p. 463, doi. 10.1002/ardp.201500096
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- Publication type:
- Article
Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2.
- Published in:
- Nature, 2010, v. 465, n. 7301, p. 1084, doi. 10.1038/nature09128
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- Publication type:
- Article
A viral RNA-dependent RNA polymerase inhibitor VV116 broadly inhibits human coronaviruses and has synergistic potency with 3CLpro inhibitor nirmatrelvir.
- Published in:
- Signal Transduction & Targeted Therapy, 2023, v. 8, n. 1, p. 1, doi. 10.1038/s41392-023-01587-1
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- Publication type:
- Article
A Statistical Thermodynamic Model for Ligands Interacting With Ion Channels: Theoretical Model and Experimental Validation of the KCNQ2 Channel.
- Published in:
- Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00150
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- Publication type:
- Article
Answer for questions of repeated measurements of variance analysis and distribution test of data — Authors' reply.
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- 2022
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- Publication type:
- Letter
Inhibited peroxidase activity of peroxiredoxin 1 by palmitic acid exacerbates nonalcoholic steatohepatitis in male mice.
- Published in:
- Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-55939-2
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- Publication type:
- Article
iDrug: a web-accessible and interactive drug discovery and design platform.
- Published in:
- Journal of Cheminformatics, 2014, v. 6, n. 1, p. 1, doi. 10.1186/1758-2946-6-28
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- Publication type:
- Article
In Silico target fishing: addressing a "Big Data" problem by ligand-based similarity rankings with data fusion.
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- Journal of Cheminformatics, 2014, v. 6, n. 1, p. 1, doi. 10.1186/1758-2946-6-33
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- Publication type:
- Article
Estimation of acute oral toxicity in rat using local lazy learning.
- Published in:
- Journal of Cheminformatics, 2014, v. 6, n. 1, p. 1, doi. 10.1186/1758-2946-6-26
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- Publication type:
- Article
iDrug: a web-accessible and interactive drug discovery and design platform.
- Published in:
- Journal of Cheminformatics, 2014, v. 6, n. 1, p. 1, doi. 10.1186/1758-2946-6-28
- By:
- Publication type:
- Article
Estimation of acute oral toxicity in rat using local lazy learning.
- Published in:
- Journal of Cheminformatics, 2014, v. 6, n. 1, p. 1, doi. 10.1186/1758-2946-6-26
- By:
- Publication type:
- Article
A Peptide Binder of E3 Ligase Adaptor SPOP Disrupts Oncogenic SPOP‐Protein Interactions in Kidney Cancer Cells.
- Published in:
- Chinese Journal of Chemistry, 2021, v. 39, n. 2, p. 274, doi. 10.1002/cjoc.202000462
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- Publication type:
- Article
Synthesis and Biological Evaluation of 1,3,3,4-Tetrasubstituted Pyrrolidine CCR5 Receptor Antagonists. Discovery of a Potent and Orally Bioavailable Anti-HIV Agent.
- Published in:
- ChemMedChem, 2007, v. 2, n. 2, p. 187, doi. 10.1002/cmdc.200600182
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- Publication type:
- Article
Structures and mechanism for the design of highly potent glucocorticoids.
- Published in:
- Cell Research, 2014, v. 24, n. 6, p. 713, doi. 10.1038/cr.2014.52
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- Publication type:
- Article
The gating charge pathway of an epilepsy-associated potassium channel accommodates chemical ligands.
- Published in:
- Cell Research, 2013, v. 23, n. 9, p. 1106, doi. 10.1038/cr.2013.82
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- Publication type:
- Article
Why are oseltamivir and zanamivir effective against the newly emerged influenza A virus (A/H1N1)?
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- 2009
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- Publication type:
- Letter
Conformational sampling on acid-sensing ion channel 1 (ASIC1): implication for a symmetric conformation.
- Published in:
- 2009
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- Publication type:
- Letter
Structural and Functional Analysis of Laninamivir and its Octanoate Prodrug Reveals Group Specific Mechanisms for Influenza NA Inhibition.
- Published in:
- PLoS Pathogens, 2011, v. 7, n. 10, p. 1, doi. 10.1371/journal.ppat.1002249
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- Publication type:
- Article
Hyrtiosal, a PTP1B Inhibitor from the Marine Sponge Hyrtios erectus, Shows Extensive Cellular Effects on PI3K/AKT Activation, Glucose Transport, and TGFβ/Smad2 Signaling.
- Published in:
- ChemBioChem, 2007, v. 8, n. 2, p. 187, doi. 10.1002/cbic.200600349
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- Publication type:
- Article
Molecular-Dynamics-Simulation-Driven Design of a Protease-Responsive Probe for In-Vivo Tumor Imaging.
- Published in:
- Advanced Materials, 2014, v. 26, n. 48, p. 8174, doi. 10.1002/adma.201403547
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- Article
Two disparate ligand-binding sites in the human P2Y<sub>1</sub> receptor.
- Published in:
- Nature, 2015, v. 520, n. 7547, p. 317, doi. 10.1038/nature14287
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- Publication type:
- Article
Structure of the human P2Y<sub>12</sub> receptor in complex with an antithrombotic drug.
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- Nature, 2014, v. 509, n. 7498, p. 115, doi. 10.1038/nature13083
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- Publication type:
- Article
Agonist-bound structure of the human P2Y<sub>12</sub> receptor.
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- Nature, 2014, v. 509, n. 7498, p. 119, doi. 10.1038/nature13288
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- Publication type:
- Article
Enantioselective drug-protein interaction between mexiletine and plasma protein.
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- Journal of Pharmacy & Pharmacology, 2012, v. 64, n. 6, p. 792, doi. 10.1111/j.2042-7158.2012.01487.x
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- Publication type:
- Article
Potent and selective inhibitors of Staphylococcus epidermidis tryptophanyl-tRNA synthetase.
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- Journal of Antimicrobial Chemotherapy (JAC), 2007, v. 60, n. 3, p. 502, doi. 10.1093/jac/dkm229
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- Publication type:
- Article
Multi-instance learning of graph neural networks for aqueous pKa prediction.
- Published in:
- Bioinformatics, 2022, v. 38, n. 3, p. 792, doi. 10.1093/bioinformatics/btab714
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- Publication type:
- Article
Drug repurposing against breast cancer by integrating drug-exposure expression profiles and drug–drug links based on graph neural network.
- Published in:
- Bioinformatics, 2021, v. 37, n. 18, p. 2930, doi. 10.1093/bioinformatics/btab191
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- Publication type:
- Article
TransformerCPI: improving compound–protein interaction prediction by sequence-based deep learning with self-attention mechanism and label reversal experiments.
- Published in:
- Bioinformatics, 2020, v. 36, n. 16, p. 4406, doi. 10.1093/bioinformatics/btaa524
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- Publication type:
- Article
KinomeX: a web application for predicting kinome-wide polypharmacology effect of small molecules.
- Published in:
- Bioinformatics, 2019, v. 35, n. 24, p. 5354, doi. 10.1093/bioinformatics/btz519
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- Publication type:
- Article
Unraveling the CDK9/PP2A/ERK Network in Transcriptional Pause Release and Complement Activation in KRAS‐mutant Cancers.
- Published in:
- Advanced Science, 2024, v. 11, n. 41, p. 1, doi. 10.1002/advs.202404926
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- Publication type:
- Article
STING agonist-boosted mRNA immunization via intelligent design of nanovaccines for enhancing cancer immunotherapy.
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- National Science Review, 2023, v. 10, n. 10, p. 1, doi. 10.1093/nsr/nwad214
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- Publication type:
- Article
Molecular basis for allosteric agonism and G protein subtype selectivity of galanin receptors.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29072-3
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- Publication type:
- Article
Structural basis of leukotriene B4 receptor 1 activation.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28820-9
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- Publication type:
- Article
Potential treatment of COVID-19 by inhibitors of human dihydroorotate dehydrogenase.
- Published in:
- Protein & Cell, 2020, v. 11, n. 10, p. 699, doi. 10.1007/s13238-020-00769-9
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- Publication type:
- Article
AL3810, a multi-tyrosine kinase inhibitor, exhibits potent anti-angiogenic and anti-tumour activity via targeting VEGFR, FGFR and PDGFR.
- Published in:
- Journal of Cellular & Molecular Medicine, 2012, v. 16, n. 10, p. 2321, doi. 10.1111/j.1582-4934.2012.01541.x
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- Publication type:
- Article
In silico ADME/T modelling for rational drug design.
- Published in:
- Quarterly Reviews of Biophysics, 2015, v. 48, n. 4, p. 488, doi. 10.1017/S0033583515000190
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- Publication type:
- Article
Inherent Dynamics of the Acid-Sensing Ion Channel 1 Correlates with the Gating Mechanism.
- Published in:
- PLoS Biology, 2009, v. 7, n. 7, p. 1, doi. 10.1371/journal.pbio.1000151
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- Publication type:
- Article