Works matching AU Jiang, Hualiang

Results: 204

The 2009 pandemic H1N1 neuraminidase N1 lacks the 150-cavity in its active site.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 10, p. 1266, doi. 10.1038/nsmb.1909

By:

Qing Li;
Jianxun Qi;
Wei Zhang;
Vavricka, Christopher J.;
Yi Shi;
Jinhua Wei;
Enguang Feng;
Jingshan Shen;
Jilong Chen;
Di Liu;
Jianhua He;
Jinghua Yan;
Hong Liu;
Hualiang Jiang;
Maikun Teng;
Xuebing Li;
Gao, George F.

Publication type:

Article

Computational chemical biology and drug design: Facilitating protein structure, function, and modulation studies.

Published in:

Medicinal Research Reviews, 2018, v. 38, n. 3, p. 914, doi. 10.1002/med.21483

By:

Zheng, Mingyue;
Zhao, Jihui;
Cui, Chen;
Fu, Zunyun;
Li, Xutong;
Liu, Xiaohong;
Ding, Xiaoyu;
Tan, Xiaoqin;
Li, Fei;
Luo, Xiaomin;
Chen, Kaixian;
Jiang, Hualiang

Publication type:

Article

Chemical and biochemical approaches in the study of histone methylation and demethylation.

Published in:

Medicinal Research Reviews, 2012, v. 32, n. 4, p. 815, doi. 10.1002/mrr.20228

By:

Li, Keqin Kathy;
Luo, Cheng;
Wang, Dongxia;
Jiang, Hualiang;
Zheng, Y. George

Publication type:

Article

Synthesis of polysubstituted β-amino cyclohexane carboxylic acids via Diels-Alder reaction using Ni(II)-complex stabilized β-alanine derived dienes.

Published in:

Amino Acids, 2013, v. 44, n. 2, p. 791, doi. 10.1007/s00726-012-1404-x

By:

Ding, Xiao;
Wang, Hengshuai;
Wang, Jiang;
Wang, Sinan;
Lin, Daizong;
Lv, Li;
Zhou, Yu;
Luo, Xiaomin;
Jiang, Hualiang;
Aceña, José;
Soloshonok, Vadim;
Liu, Hong

Publication type:

Article

Diastereoselective Michael reaction of chiral nickel(II) glycinate with nitroalkenes for asymmetric synthesis of β-substituted α,γ-diaminobutyric acid derivatives in water.

Published in:

Amino Acids, 2012, v. 42, n. 5, p. 1685, doi. 10.1007/s00726-011-0870-x

By:

Wang, Jiang;
Ji, Xun;
Shi, Jianmei;
Sun, Haifeng;
Jiang, Hualiang;
Liu, Hong

Publication type:

Article

TarPred: a web application for predicting therapeutic and side effect targets of chemical compounds.

Published in:

Bioinformatics, 2015, v. 31, n. 12, p. 2049, doi. 10.1093/bioinformatics/btv099

By:

Xian Liu;
Yuan Gao;
Jianlong Peng;
Yuan Xu;
YulanWang;
Nannan Zhou;
Jing Xing;
Xiaomin Luo;
Hualiang Jiang;
Mingyue Zheng

Publication type:

Article

In silico site of metabolism prediction for human UGT-catalyzed reactions.

Published in:

Bioinformatics, 2014, v. 30, n. 3, p. 398, doi. 10.1093/bioinformatics/btt681

By:

Peng, Jianlong;
Lu, Jing;
Shen, Qiancheng;
Zheng, Mingyue;
Luo, Xiaomin;
Zhu, Weiliang;
Jiang, Hualiang;
Chen, Kaixian

Publication type:

Article

ChemMapper: a versatile web server for exploring pharmacology and chemical structure association based on molecular 3D similarity method.

Published in:

Bioinformatics, 2013, v. 29, n. 14, p. 1827, doi. 10.1093/bioinformatics/btt270

By:

Gong, Jiayu;
Cai, Chaoqian;
Liu, Xiaofeng;
Ku, Xin;
Jiang, Hualiang;
Gao, Daqi;
Li, Honglin

Publication type:

Article

Site of metabolism prediction for six biotransformations mediated by cytochromes P450.

Published in:

Bioinformatics, 2009, v. 25, n. 10, p. 1251, doi. 10.1093/bioinformatics/btp140

By:

Mingyue Zheng;
Xiaomin Luo;
Qiancheng Shen;
Yong Wang;
Yun Du;
Weiliang Zhu;
Hualiang Jiang

Publication type:

Article

DrugViz: a Cytoscape plugin for visualizing and analyzing small molecule drugs in biological networks.

Published in:

Bioinformatics, 2008, v. 24, n. 18, p. 2117, doi. 10.1093/bioinformatics/btn389

By:

Bing Xiong;
Ke Liu;
Jie Wu;
David L. Burk;
Hualiang Jiang;
Jingkang Shen

Publication type:

Article

Mutagenic probability estimation of chemical compounds by a novel molecular electrophilicity vector and support vector machine.

Published in:

Bioinformatics, 2006, v. 22, n. 17, p. 2099, doi. 10.1093/bioinformatics/btl352

By:

Mingyue Zheng;
Zhiguo Liu;
Chunxia Xue;
Weiliang Zhu;
Kaixian Chen;
Xiaomin Luo;
Hualiang Jiang

Publication type:

Article

Generation of a High‐Precision Whole Liver Panorama and Cross‐Scale 3D Pathological Analysis for Hepatic Fibrosis.

Published in:

Advanced Science, 2025, v. 12, n. 19, p. 1, doi. 10.1002/advs.202502744

By:

Zhang, Xiaochuan;
Yang, Weicheng;
Li, Xiaoliang;
Zhao, Yanli;
Xie, Zongneng;
Li, Shuangqu;
Zeng, Yue;
Hao, Xiaoxu;
Xin, Xiaohong;
Zhang, Yu;
Feng, Zixuan;
Jiang, Hualiang;
Gao, Zhaobing;
Yin, Xianzhen

Publication type:

Article

Unraveling the CDK9/PP2A/ERK Network in Transcriptional Pause Release and Complement Activation in KRAS‐mutant Cancers.

Published in:

Advanced Science, 2024, v. 11, n. 41, p. 1, doi. 10.1002/advs.202404926

By:

Wang, Yafang;
Xu, Lansong;
Ling, Lijun;
Yao, Mingyue;
Shi, Shangxuan;
Yu, Chengcheng;
Li, Yingnian;
Shen, Jie;
Jiang, Hualiang;
Xie, Chengying

Publication type:

Article

Microwave-Assisted Dehalogenation of α-Haloketones by Zinc and Ammonium Chloride in Alcohol.

Published in:

Synthetic Communications, 2008, v. 38, n. 4, p. 567, doi. 10.1080/00397910701797889

By:

Li, Jian;
Ye, Deju;
Liu, Hong;
Luo, Xiaoming;
Jiang, Hualiang

Publication type:

Article

Ionic-Liquid-Supported Total Synthesis of Sansalvamide A Peptide.

Published in:

Synthetic Communications, 2008, v. 38, n. 2, p. 239, doi. 10.1080/00397910701749633

By:

Chen, Ling;
Zheng, Mingfang;
Zhou, Yu;
Liu, Hong;
Jiang, Hualiang

Publication type:

Article

Transformation of Aryl Acyloin O-Alkyl and O-Phenyl Derivatives to Ketones.

Published in:

Synthetic Communications, 2007, v. 37, n. 1, p. 149, doi. 10.1080/00397910600978564

By:

Yao, Zhiyi;
Ye, Deju;
Liu, Hong;
Chen, Kaixian;
Jiang, Hualiang

Publication type:

Article

Microwave‐Assisted Synthesis of 2‐Amino‐thiophene‐3‐Carboxylic Derivatives Under Solvent‐Free Conditions.

Published in:

Synthetic Communications, 2005, v. 35, n. 10, p. 1351, doi. 10.1081/SCC-200057268

By:

Huang, Wei;
Li, Jian;
Tang, Jing;
Liu, Hong;
Shen, Jianhua;
Jiang, Hualiang

Publication type:

Article

Structural and Functional Analysis of Laninamivir and its Octanoate Prodrug Reveals Group Specific Mechanisms for Influenza NA Inhibition.

Published in:

PLoS Pathogens, 2011, v. 7, n. 10, p. 1, doi. 10.1371/journal.ppat.1002249

By:

Vavricka, Christopher J.;
Qing Li;
Wu, Yan;
Qi, Jianxun;
Wang, Mingyang;
Liu, Yue;
Gao, Feng;
Liu, Jun;
Feng, Enguang;
He, Jianhua;
Wang, Jinfang;
Liu, Hong;
Jiang, Hualiang;
Gao, George F.

Publication type:

Article

Crowdsourced identification of multi-target kinase inhibitors for RET- and TAU- based disease: The Multi-Targeting Drug DREAM Challenge.

Published in:

PLoS Computational Biology, 2021, v. 17, n. 9, p. 1, doi. 10.1371/journal.pcbi.1009302

By:

Xiong, Zhaoping;
Jeon, Minji;
Allaway, Robert J.;
Kang, Jaewoo;
Park, Donghyeon;
Lee, Jinhyuk;
Jeon, Hwisang;
Ko, Miyoung;
Jiang, Hualiang;
Zheng, Mingyue;
Tan, Aik Choon;
Guo, Xindi;
Dang, Kristen K.;
Tropsha, Alex;
Hecht, Chana;
Das, Tirtha K.;
Carlson, Heather A.;
Abagyan, Ruben;
Guinney, Justin;
Schlessinger, Avner

Publication type:

Article

Microwave-Assisted One-Step Synthesis of Acetophenones via Palladium-Catalyzed Regioselective Arylation of Vinyloxytrimethylsilane.

Published in:

Advanced Synthesis & Catalysis, 2012, v. 354, n. 17, p. 3231, doi. 10.1002/adsc.201200334

By:

Qian, Wangke;
Zhang, Lei;
Sun, Haifeng;
Jiang, Hualiang;
Liu, Hong

Publication type:

Article

Highly Enantioselective Michael Addition of 2-Oxindole- 3-carboxylate Esters to Nitroolefins Promoted by Cinchona Alkaloid-Thiourea-Brønsted Acid Cocatalysts.

Published in:

Advanced Synthesis & Catalysis, 2012, v. 354, n. 11/12, p. 2151, doi. 10.1002/adsc.201200206

By:

Chen, Xianjie;
Zhu, Wei;
Qian, Wangke;
Feng, Enguang;
Zhou, Yu;
Wang, Jinfang;
Jiang, Hualiang;
Yao, Zhu-Jun;
Liu, Hong

Publication type:

Article

Erratum: Inhibition of GPR40 protects MIN6 β cells from palmitate-induced ER stress and apoptosis.

Published in:

Journal of Cellular Biochemistry, 2013, v. 114, n. 5, p. 1216, doi. 10.1002/jcb.24514

By:

Wu, Jinwei;
Sun, Peng;
Zhang, Xiaodong;
Liu, Hong;
Jiang, Hualiang;
Zhu, Weiliang;
Wang, Heyao

Publication type:

Article

PDE5 inhibitor promotes melanin synthesis through the PKG pathway in B16 melanoma cells.

Published in:

Journal of Cellular Biochemistry, 2012, v. 113, n. 8, p. 2738, doi. 10.1002/jcb.24147

By:

Zhang, Xiaodong;
Yan, Guirui;
Ji, Jun;
Wu, Jingwei;
Sun, Xiaoyun;
Shen, Jingshan;
Jiang, Hualiang;
Wang, Heyao

Publication type:

Article

Inhibition of GPR40 protects MIN6 β cells from palmitate-induced ER stress and apoptosis.

Published in:

Journal of Cellular Biochemistry, 2012, v. 113, n. 4, p. 1152, doi. 10.1002/jcb.23450

By:

Wu, Jinwei;
Sun, Peng;
Zhang, Xiaodong;
Liu, Hong;
Jiang, Hualiang;
Zhu, Weiliang;
Wang, Heyao

Publication type:

Article

Potent and selective inhibitors of Staphylococcus epidermidis tryptophanyl-tRNA synthetase.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2007, v. 60, n. 3, p. 502, doi. 10.1093/jac/dkm229

By:

Yang Wu;
Kunqian Yu;
Bin Xu;
Lili Chen;
Xianglong Chen;
Jialing Mao;
Antoine Danchin;
Xu Shen;
Di Qu;
Hualiang Jiang

Publication type:

Article

A Genetic Algorithm Based Support Vector Machine Model for Blood-Brain Barrier Penetration Prediction.

Published in:

2015

By:

Zhang, Daqing;
Xiao, Jianfeng;
Zhou, Nannan;
Zheng, Mingyue;
Luo, Xiaomin;
Jiang, Hualiang;
Chen, Kaixian

Publication type:

journal article

Metadynamics Simulation Study on the Conformational Transformation of HhaI Methyltransferase: An Induced-Fit Base-Flipping Hypothesis.

Published in:

BioMed Research International, 2014, v. 2014, p. 1, doi. 10.1155/2014/304563

By:

Lu Jin;
Fei Ye;
Dan Zhao;
Shijie Chen;
Kongkai Zhu;
Mingyue Zheng;
Ren-Wang Jiang;
Hualiang Jiang;
Cheng Luo

Publication type:

Article

Characterizing the interactions of two lipid modifications with lipid rafts: farnesyl anchors vs. palmitoyl anchors.

Published in:

European Biophysics Journal, 2018, v. 47, n. 1, p. 19, doi. 10.1007/s00249-017-1217-7

By:

Zhang, Tao;
Luo, Qichao;
Yang, Linlin;
Jiang, Hualiang;
Yang, Huaiyu

Publication type:

Article

Probing the structure and dynamics of caveolin-1 in a caveolae-mimicking asymmetric lipid bilayer model.

Published in:

European Biophysics Journal, 2016, v. 45, n. 6, p. 511, doi. 10.1007/s00249-016-1118-1

By:

Liu, Hanqi;
Yang, Linlin;
Zhang, Qiansen;
Mao, Lingxue;
Jiang, Hualiang;
Yang, Huaiyu

Publication type:

Article

Protein Tyrosine Phosphatase U (PTPRU) is Required for Glioma Growth and Motility.

Published in:

Carcinogenesis, 2014, v. 35, n. 8, p. 1, doi. 10.1093/carcin/bgu123

By:

Zhu, Zhichuan;
Liu, Yongjie;
Li, Kui;
Liu, Jiwei;
Wang, Hongtao;
Sun, Bing;
Xiong, Zhiqi;
Jiang, Hualiang;
Zheng, Jing;
Hu, Zelan

Publication type:

Article

Molecular basis for allosteric agonism and G protein subtype selectivity of galanin receptors.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29072-3

By:

Duan, Jia;
Shen, Dan-Dan;
Zhao, Tingting;
Guo, Shimeng;
He, Xinheng;
Yin, Wanchao;
Xu, Peiyu;
Ji, Yujie;
Chen, Li-Nan;
Liu, Jinyu;
Zhang, Huibing;
Liu, Qiufeng;
Shi, Yi;
Cheng, Xi;
Jiang, Hualiang;
Eric Xu, H.;
Zhang, Yan;
Xie, Xin;
Jiang, Yi

Publication type:

Article

Structural basis of leukotriene B4 receptor 1 activation.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-28820-9

By:

Wang, Na;
He, Xinheng;
Zhao, Jing;
Jiang, Hualiang;
Cheng, Xi;
Xia, Yu;
Eric Xu, H.;
He, Yuanzheng

Publication type:

Article

αExtractor: a system for automatic extraction of chemical information from biomedical literature.

Published in:

2024

By:

Xiong, Jiacheng;
Liu, Xiaohong;
Li, Zhaojun;
Xiao, Hongzhong;
Wang, Guangchao;
Niu, Zhenjiang;
Fei, Chaoyuan;
Zhong, Feisheng;
Wang, Gang;
Zhang, Wei;
Fu, Zunyun;
Liu, Zhiguo;
Chen, Kaixian;
Jiang, Hualiang;
Zheng, Mingyue

Publication type:

Letter

PanGu Drug Model: learn a molecule like a human.

Published in:

2023

By:

Lin, Xinyuan;
Xu, Chi;
Xiong, Zhaoping;
Zhang, Xinfeng;
Ni, Ningxi;
Ni, Bolin;
Chang, Jianlong;
Pan, Ruiqing;
Wang, Zidong;
Yu, Fan;
Tian, Qi;
Jiang, Hualiang;
Zheng, Mingyue;
Qiao, Nan

Publication type:

Letter

Facing small and biased data dilemma in drug discovery with enhanced federated learning approaches.

Published in:

SCIENCE CHINA Life Sciences, 2022, v. 65, n. 3, p. 529, doi. 10.1007/s11427-021-1946-0

By:

Xiong, Zhaoping;
Cheng, Ziqiang;
Lin, Xinyuan;
Xu, Chi;
Liu, Xiaohong;
Wang, Dingyan;
Luo, Xiaomin;
Zhang, Yong;
Jiang, Hualiang;
Qiao, Nan;
Zheng, Mingyue

Publication type:

Article

Cryo-EM structure determination captures new chemical modification of protein.

Published in:

SCIENCE CHINA Life Sciences, 2021, v. 64, n. 10, p. 1781, doi. 10.1007/s11427-021-1886-8

By:

Jiang, Hualiang

Publication type:

Article

Beneficial effects exerted by hydroxychloroquine in treating COVID-19 patients via protecting multiple organs.

Published in:

2021

By:

Yu, Bo;
Li, Chenze;
Chen, Peng;
Li, Jia;
Jiang, Hualiang;
Wang, Dao-Wen

Publication type:

Letter

Erratum to: Low dose of hydroxychloroquine reduces fatality of critically ill patients with COVID-19.

Published in:

2020

By:

Yu, Bo;
Li, Chenze;
Chen, Peng;
Zhou, Ning;
Wang, Luyun;
Li, Jia;
Jiang, Hualiang;
Wang, Dao-Wen

Publication type:

Correction Notice

Low dose of hydroxychloroquine reduces fatality of critically ill patients with COVID-19.

Published in:

SCIENCE CHINA Life Sciences, 2020, v. 63, n. 10, p. 1515, doi. 10.1007/s11427-020-1732-2

By:

Yu, Bo;
Li, Chenze;
Chen, Peng;
Zhou, Ning;
Wang, Luyun;
Li, Jia;
Jiang, Hualiang;
Wang, Dao-Wen

Publication type:

Article

Dynamic modifications of biomacromolecules: mechanism and chemical interventions.

Published in:

SCIENCE CHINA Life Sciences, 2019, v. 62, n. 11, p. 1459, doi. 10.1007/s11427-019-9823-1

By:

Wang, Chu;
Zou, Peng;
Yang, Caiguang;
Liu, Lei;
Cheng, Liang;
He, Xiaopeng;
Zhang, Liang;
Zhang, Yan;
Jiang, Hualiang;
Chen, Peng R.

Publication type:

Article

Nature brings new avenues to the therapy of central nervous system diseases—An overview of possible treatments derived from natural products.

Published in:

SCIENCE CHINA Life Sciences, 2019, v. 62, n. 10, p. 1332, doi. 10.1007/s11427-019-9587-y

By:

Zhang, Junchi;
He, Yang;
Jiang, Xiangrui;
Jiang, Hualiang;
Shen, Jingshan

Publication type:

Article

Artificial intelligence in drug design.

Published in:

SCIENCE CHINA Life Sciences, 2018, v. 61, n. 10, p. 1191, doi. 10.1007/s11427-018-9342-2

By:

Zhong, Feisheng;
Xing, Jing;
Li, Xutong;
Liu, Xiaohong;
Fu, Zunyun;
Xiong, Zhaoping;
Lu, Dong;
Wu, Xiaolong;
Zhao, Jihui;
Tan, Xiaoqin;
Li, Fei;
Luo, Xiaomin;
Li, Zhaojun;
Chen, Kaixian;
Zheng, Mingyue;
Jiang, Hualiang

Publication type:

Article

In Silico target fishing: addressing a "Big Data" problem by ligand-based similarity rankings with data fusion.

Published in:

Journal of Cheminformatics, 2014, v. 6, n. 1, p. 1, doi. 10.1186/1758-2946-6-33

By:

Xian Liu;
Yuan Xu;
Shanshan Li;
Yulan Wang;
Jianlong Peng;
Cheng Luo;
Xiaomin Luo;
Mingyue Zheng;
Kaixian Chen;
Hualiang Jiang

Publication type:

Article

iDrug: a web-accessible and interactive drug discovery and design platform.

Published in:

Journal of Cheminformatics, 2014, v. 6, n. 1, p. 1, doi. 10.1186/1758-2946-6-28

By:

Xia Wang;
Haipeng Chen;
Feng Yang;
Jiayu Gong;
Shiliang Li;
Jianfeng Pei;
Xiaofeng Liu;
Hualiang Jiang;
Luhua Lai;
Honglin Li

Publication type:

Article

Estimation of acute oral toxicity in rat using local lazy learning.

Published in:

Journal of Cheminformatics, 2014, v. 6, n. 1, p. 1, doi. 10.1186/1758-2946-6-26

By:

Jing Lu;
Jianlong Peng;
Jinan Wang;
Qiancheng Shen;
Yi Bi;
Likun Gong;
Mingyue Zheng;
Xiaomin Luo;
Weiliang Zhu;
Hualiang Jiang;
Kaixian Chen

Publication type:

Article

iDrug: a web-accessible and interactive drug discovery and design platform.

Published in:

Journal of Cheminformatics, 2014, v. 6, n. 1, p. 1, doi. 10.1186/1758-2946-6-28

By:

Wang, Xia;
Chen, Haipeng;
Yang, Feng;
Gong, Jiayu;
Li, Shiliang;
Pei, Jianfeng;
Liu, Xiaofeng;
Jiang, Hualiang;
Lai, Luhua;
Li, Honglin

Publication type:

Article

Estimation of acute oral toxicity in rat using local lazy learning.

Published in:

Journal of Cheminformatics, 2014, v. 6, n. 1, p. 1, doi. 10.1186/1758-2946-6-26

By:

Lu, Jing;
Peng, Jianlong;
Wang, Jinan;
Shen, Qiancheng;
Bi, Yi;
Gong, Likun;
Zheng, Mingyue;
Luo, Xiaomin;
Zhu, Weiliang;
Jiang, Hualiang;
Chen, Kaixian

Publication type:

Article

A Peptide Binder of E3 Ligase Adaptor SPOP Disrupts Oncogenic SPOP‐Protein Interactions in Kidney Cancer Cells.

Published in:

Chinese Journal of Chemistry, 2021, v. 39, n. 2, p. 274, doi. 10.1002/cjoc.202000462

By:

Wang, Zhen;
Zhang, Hao;
Chen, Baoen;
Ouyang, Sisheng;
Zheng, Tong;
Zhou, Ran;
Dong, Ze;
Huang, Yue;
Zhang, Tao;
Jiang, Hualiang;
Gan, Jianhua;
Luo, Cheng;
Yang, Cai‐Guang

Publication type:

Article

Total Synthesis of Cytosporone B.

Published in:

Chinese Journal of Chemistry, 2010, v. 28, n. 6, p. 1041, doi. 10.1002/cjoc.201090163

By:

Huang, He;
Zhang, Lei;
Zhang, Xiaodong;
Ji, Xun;
Ding, Xiao;
Shen, Xu;
Jiang, Hualiang;
Liu, Hong

Publication type:

Article

First Reaction of a Chiral Gly-Ni(II) Complex in Water.

Published in:

Chinese Journal of Chemistry, 2010, v. 28, n. 3, p. 422, doi. 10.1002/cjoc.201090090

By:

Liu, Guannan;
Zhou, Yu;
Ding, Xiao;
Wang, Jiang;
Jiang, Hualiang;
Liu, Hong

Publication type:

Article