Works by Ji, Ru-Rong

Results: 68

Identification and characterization of novel candidate compounds targeting 6- and 7-transmembrane μ-opioid receptor isoforms.

Published in:

2021

By:

Muralidharan, Arjun;
Samoshkin, Alexander;
Convertino, Marino;
Piltonen, Marjo Hannele;
Gris, Pavel;
Wang, Jian;
Jiang, Changyu;
Klares, Richard;
Linton, Alexander;
Ji, Ru‐Rong;
Maixner, William;
Dokholyan, Nikolay V.;
Mogil, Jeffrey S.;
Diatchenko, Luda;
Klares, Richard 3rd;
Ji, Ru-Rong

Publication type:

journal article

Design of an equilibrative nucleoside transporter subtype 1 inhibitor for pain relief.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-54914-7

By:

Wright, Nicholas J.;
Matsuoka, Yutaka;
Park, Hyeri;
He, Wei;
Webster, Caroline G.;
Furutani, Kenta;
Fedor, Justin G.;
McGinnis, Aidan;
Zhao, Yiquan;
Chen, Ouyang;
Bang, Sangsu;
Fan, Ping;
Spasojevic, Ivan;
Hong, Jiyong;
Ji, Ru-Rong;
Lee, Seok-Yong

Publication type:

Article

Lipoxin A4 inhibits microglial activation and reduces neuroinflammation and neuropathic pain after spinal cord hemisection.

Published in:

2016

By:

Martini, Alessandra Cadete;
Berta, Temugin;
Forner, Stefânia;
Gang Chen;
Bento, Allisson Freire;
Ru-Rong Ji;
Rae, Giles Alexander;
Chen, Gang;
Ji, Ru-Rong

Publication type:

journal article

Interferon alpha inhibits spinal cord synaptic and nociceptive transmission via neuronal-glial interactions.

Published in:

Scientific Reports, 2016, p. 34356, doi. 10.1038/srep34356

By:

Liu, Chien-Cheng;
Gao, Yong-Jing;
Luo, Hao;
Berta, Temugin;
Xu, Zhen-Zhong;
Ji, Ru-Rong;
Tan, Ping-Heng

Publication type:

Article

TLR signaling adaptor protein MyD88 in primary sensory neurons contributes to persistent inflammatory and neuropathic pain and neuroinflammation.

Published in:

Scientific Reports, 2016, p. 28188, doi. 10.1038/srep28188

By:

Liu, Xing-Jun;
Liu, Tong;
Chen, Gang;
Wang, Bing;
Yu, Xiao-Lu;
Yin, Cui;
Ji, Ru-Rong

Publication type:

Article

Distinct Analgesic Actions of DHA and DHA-Derived Specialized Pro-Resolving Mediators on Post-operative Pain After Bone Fracture in Mice.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00412

By:

Zhang, Linlin;
Terrando, Niccolò;
Xu, Zhen-Zhong;
Bang, Sangsu;
Jordt, Sven-Eric;
Maixner, William;
Serhan, Charles N.;
Ji, Ru-Rong

Publication type:

Article

IL-23 Enhances C-Fiber-Mediated and Blue Light-Induced Spontaneous Pain in Female Mice.

Published in:

Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.787565

By:

Ji, Jasmine;
He, Qianru;
Luo, Xin;
Bang, Sangsu;
Matsuoka, Yutaka;
McGinnis, Aidan;
Nackley, Andrea G.;
Ji, Ru-Rong

Publication type:

Article

Interferons in Pain and Infections: Emerging Roles in Neuro-Immune and Neuro-Glial Interactions.

Published in:

Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.783725

By:

Tan, Ping-Heng;
Ji, Jasmine;
Yeh, Chun-Chang;
Ji, Ru-Rong

Publication type:

Article

Roles of inflammation, neurogenic inflammation, and neuroinflammation in pain.

Published in:

Journal of Anesthesia, 2019, v. 33, n. 1, p. 131, doi. 10.1007/s00540-018-2579-4

By:

Matsuda, Megumi;
Huh, Yul;
Ji, Ru-Rong

Publication type:

Article

Follistatin drives neuropathic pain in mice through IGF1R signaling in nociceptive neurons.

Published in:

Science Translational Medicine, 2024, v. 16, n. 769, p. 1, doi. 10.1126/scitranslmed.adi1564

By:

Jiang, Bao-Chun;
Ling, Yue-Juan;
Xu, Meng-Lin;
Gu, Jun;
Wu, Xiao-Bo;
Sha, Wei-Lin;
Tian, Tian;
Bai, Xue-Hui;
Li, Nan;
Jiang, Chang-Yu;
Chen, Ouyang;
Ma, Ling-Jie;
Zhang, Zhi-Jun;
Qin, Yi-Bin;
Zhu, Meixuan;
Yuan, Hong-Jie;
Wu, Long-Jun;
Ji, Ru-Rong;
Gao, Yong-Jing

Publication type:

Article

Third Special Issue on Mechanisms of Pain and Itch.

Published in:

2022

By:

Ji, Ru-Rong

Publication type:

Editorial

Molecular Sensors of Temperature, Pressure, and Pain with Special Focus on TRPV1, TRPM8, and PIEZO2 Ion Channels.

Published in:

Neuroscience Bulletin, 2021, v. 37, n. 12, p. 1745, doi. 10.1007/s12264-021-00798-2

By:

Ji, Ru-Rong;
Lee, Seok-Yong

Publication type:

Article

Emerging Role of PD-1 in the Central Nervous System and Brain Diseases.

Published in:

Neuroscience Bulletin, 2021, v. 37, n. 8, p. 1188, doi. 10.1007/s12264-021-00683-y

By:

Zhao, Junli;
Roberts, Alexus;
Wang, Zilong;
Savage, Justin;
Ji, Ru-Rong

Publication type:

Article

Differential Inhibition of Nav1.7 and Neuropathic Pain by Hybridoma-Produced and Recombinant Monoclonal Antibodies that Target Nav1.7.

Published in:

Neuroscience Bulletin, 2018, v. 34, n. 1, p. 22, doi. 10.1007/s12264-018-0203-0

By:

Bang, Sangsu;
Yoo, Jiho;
Gong, Xingrui;
Liu, Di;
Han, Qingjian;
Luo, Xin;
Chang, Wonseok;
Chen, Gang;
Im, Sang-Taek;
Kim, Yong Ho;
Strong, Judith A.;
Zhang, Ma-Zhong;
Zhang, Jun-Ming;
Lee, Seok-Yong;
Ji, Ru-Rong

Publication type:

Article

Recent Progress in Understanding the Mechanisms of Pain and Itch: the Second Special Issue.

Published in:

Neuroscience Bulletin, 2018, v. 34, n. 1, p. 1, doi. 10.1007/s12264-018-0204-z

By:

Ji, Ru-Rong

Publication type:

Article

Sex-Dependent Glial Signaling in Pathological Pain: Distinct Roles of Spinal Microglia and Astrocytes.

Published in:

Neuroscience Bulletin, 2018, v. 34, n. 1, p. 98, doi. 10.1007/s12264-017-0145-y

By:

Chen, Gang;
Luo, Xin;
Qadri, M. Yawar;
Berta, Temugin;
Ji, Ru-Rong

Publication type:

Article

TNF-α/TNFR1 Signaling is Required for the Full Expression of Acute and Chronic Itch in Mice <italic>via</italic> Peripheral and Central Mechanisms.

Published in:

Neuroscience Bulletin, 2018, v. 34, n. 1, p. 42, doi. 10.1007/s12264-017-0124-3

By:

Miao, Xiuhua;
Huang, Ya;
Liu, Teng-Teng;
Guo, Ran;
Wang, Bing;
Wang, Xue-Long;
Chen, Li-Hua;
Zhou, Yan;
Ji, Ru-Rong;
Liu, Tong

Publication type:

Article

Expression and Role of Voltage-Gated Sodium Channels in Human Dorsal Root Ganglion Neurons with Special Focus on Nav1.7, Species Differences, and Regulation by Paclitaxel.

Published in:

Neuroscience Bulletin, 2018, v. 34, n. 1, p. 4, doi. 10.1007/s12264-017-0132-3

By:

Chang, Wonseok;
Berta, Temugin;
Kim, Yong Ho;
Lee, Sanghoon;
Lee, Seok-Yong;
Ji, Ru-Rong

Publication type:

Article

Spinal CCL2 Promotes Central Sensitization, Long-Term Potentiation, and Inflammatory Pain via CCR2: Further Insights into Molecular, Synaptic, and Cellular Mechanisms.

Published in:

Neuroscience Bulletin, 2018, v. 34, n. 1, p. 13, doi. 10.1007/s12264-017-0106-5

By:

Xie, Rou-Gang;
Gao, Yong-Jing;
Park, Chul-Kyu;
Lu, Ning;
Luo, Ceng;
Wang, Wen-Ting;
Wu, Sheng-Xi;
Ji, Ru-Rong

Publication type:

Article

Recent progress in understanding the mechanisms of pain and itch.

Published in:

2012

By:

Ji, Ru-Rong

Publication type:

Editorial

Emerging role of Toll-like receptors in the control of pain and itch.

Published in:

Neuroscience Bulletin, 2012, v. 28, n. 2, p. 131, doi. 10.1007/s12264-012-1219-5

By:

Liu, Tong;
Gao, Yong-Jing;
Ji, Ru-Rong

Publication type:

Article

Oxidative stress induces itch via activation of transient receptor potential subtype ankyrin 1 in mice.

Published in:

Neuroscience Bulletin, 2012, v. 28, n. 2, p. 145, doi. 10.1007/s12264-012-1207-9

By:

Liu, Tong;
Ji, Ru-Rong

Publication type:

Article

Loss of NR1 Subunit of NMDARs in Primary Sensory Neurons Leads to Hyperexcitability and Pain Hypersensitivity: Involvement of Ca<sup>2+</sup> -Activated Small Conductance Potassium Channels.

Published in:

Journal of Neuroscience, 2013, v. 33, n. 33, p. 13425, doi. 10.1523/JNEUROSCI.0454-13.2013

By:

Pagadala, Promila;
Park, Chul-Kyu;
Bang, Sangsu;
Xu, Zheng-Zhong;
Xie, Rou-Gang;
Liu, Tong;
Han, Bao-Xia;
Tracey Jr, W. Daniel;
Wang, Fan;
Ji, Ru-Rong

Publication type:

Article

Differential wiring of local excitatory and inhibitory synaptic inputs to islet cells in rat spinal lamina II demonstrated by laser scanning photostimulation.

Published in:

Journal of Physiology, 2007, v. 580, n. 3, p. 815, doi. 10.1113/jphysiol.2007.128314

By:

Kato, Go;
Kawasaki, Yasuhiko;
Ji, Ru-Rong;
Strassman, Andrew M.

Publication type:

Article

Pre‐Clinical Assessment of Bupivacaine‐Loaded Poly(ester urea) Thin Films for Controlled Drug Release and Effective Pain Management After Surgery.

Published in:

Advanced Healthcare Materials, 2025, v. 14, n. 3, p. 1, doi. 10.1002/adhm.202402800

By:

Stinson, Natasha C.;
Matsuoka, Yutaka;
Agarwal, Anshu;
Dziewior, Courtney S.;
McDonald, Samantha M.;
Li, Yize;
Godwin, Kacey;
Ji, Ru‐Rong;
Becker, Matthew L.

Publication type:

Article

Controlled Transdermal Delivery of Dexamethasone for Pain Management via Photochemically 3D‐Printed Bioresorbable Microneedle Arrays.

Published in:

Advanced Healthcare Materials, 2024, v. 13, n. 31, p. 1, doi. 10.1002/adhm.202402113

By:

Bahnick, Alexander J.;
Dziewior, Courtney S.;
Li, Yize;
Chou, Amy;
Segal, Maddison;
Augustine, Emily K.;
Ji, Ru‐Rong;
Becker, Matthew L.

Publication type:

Article

Peripheral noxious stimulation induces phosphorylation of the NMDA receptor NR1 subunit at the PKC-dependent site, serine-896, in spinal cord dorsal horn neurons.

Published in:

European Journal of Neuroscience, 2004, v. 20, n. 2, p. 375, doi. 10.1111/j.1460-9568.2004.03506.x

By:

Brenner, Gary J.;
Ji, Ru‐Rong;
Shaffer, Sebastian;
Woolf, Clifford J.

Publication type:

Article

Resolving TRPV1- and TNF-α-Mediated Spinal Cord Synaptic Plasticity and Inflammatory Pain with Neuroprotectin D1.

Published in:

Journal of Neuroscience, 2011, v. 31, n. 42, p. 15072, doi. 10.1523/JNEUROSCI.2443-11.2011

By:

Park, Chul-Kyu;
Ning Lu;
Xu, Zhen-Zhong;
Tong Liu;
Serhan, Charles N.;
Ji, Ru-Rong

Publication type:

Article

Emerging targets in neuroinflammation-driven chronic pain.

Published in:

Nature Reviews Drug Discovery, 2014, v. 13, n. 7, p. 533, doi. 10.1038/nrd4334

By:

Ji, Ru-Rong;
Xu, Zhen-Zhong;
Gao, Yong-Jing

Publication type:

Article

Resolvin D5 Inhibits Neuropathic and Inflammatory Pain in Male But Not Female Mice: Distinct Actions of D-Series Resolvins in Chemotherapy-Induced Peripheral Neuropathy.

Published in:

Frontiers in Pharmacology, 2019, p. 1, doi. 10.3389/fphar.2019.00745

By:

Luo, Xin;
Gu, Yun;
Tao, Xueshu;
Serhan, Charles Nicholas;
Ji, Ru-Rong

Publication type:

Article

Different immune cells mediate mechanical pain hypersensitivity in male and female mice.

Published in:

Nature Neuroscience, 2015, v. 18, n. 8, p. 1081, doi. 10.1038/nn.4053

By:

Sorge, Robert E;
Mapplebeck, Josiane C S;
Rosen, Sarah;
Beggs, Simon;
Taves, Sarah;
Alexander, Jessica K;
Martin, Loren J;
Austin, Jean-Sebastien;
Sotocinal, Susana G;
Chen, Di;
Yang, Mu;
Shi, Xiang Qun;
Huang, Hao;
Pillon, Nicolas J;
Bilan, Philip J;
Tu, YuShan;
Klip, Amira;
Ji, Ru-Rong;
Zhang, Ji;
Salter, Michael W

Publication type:

Article

Interleukin-6 signaling mediates cartilage degradation and pain in posttraumatic osteoarthritis in a sex-specific manner.

Published in:

Science Signaling, 2022, v. 15, n. 744, p. 1, doi. 10.1126/scisignal.abn7082

By:

Liao, Yihan;
Ren, Yinshi;
Luo, Xin;
Mirando, Anthony J.;
Long, Jason T.;
Leinroth, Abigail;
Ji, Ru-Rong;
Hilton, Matthew J.

Publication type:

Article

DRAGON: A Member of the Repulsive Guidance Molecule-Related Family of Neuronal- and Muscle-Expressed Membrane Proteins Is Regulated by DRG11 and Has Neuronal Adhesive Properties.

Published in:

Journal of Neuroscience, 2004, v. 24, n. 8, p. 2027, doi. 10.1523/JNEUROSCI.4115-03.2004

By:

Samad, Tarek A.;
Srinivasan, Ashok;
Karchewski, Laurie A.;
Jeong, Sung-Jin;
Campagna, Jason A.;
Ji, Ru-Rong;
Fabrizio, David A.;
Zhang, Ying;
Lin, Herbert Y.;
Bell, Esther;
Woolf, Clifford J.

Publication type:

Article

Neuroprotectin/protectin D1 protects against neuropathic pain in mice after nerve trauma.

Published in:

Annals of Neurology, 2013, v. 74, n. 3, p. 490, doi. 10.1002/ana.23928

By:

Xu, Zhen‐Zhong;
Liu, Xing‐Jun;
Berta, Temugin;
Park, Chul‐Kyu;
Lü, Ning;
Serhan, Charles N.;
Ji, Ru‐Rong

Publication type:

Article

Inflammation and Infection in Pain and the Role of GPR37.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 22, p. 14426, doi. 10.3390/ijms232214426

By:

Zhang, Qin;
Bang, Sangsu;
Chandra, Sharat;
Ji, Ru-Rong

Publication type:

Article

Emerging Roles of Type-I Interferons in Neuroinflammation, Neurological Diseases, and Long-Haul COVID.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 22, p. 14394, doi. 10.3390/ijms232214394

By:

Tan, Ping-Heng;
Ji, Jasmine;
Hsing, Chung-Hsi;
Tan, Radika;
Ji, Ru-Rong

Publication type:

Article

Astrocytic CX43 hemichannels and gap junctions play a crucial role in development of chronic neuropathic pain following spinal cord injury.

Published in:

Glia (0894-1491), 2012, v. 60, n. 11, p. 1660, doi. 10.1002/glia.22384

By:

Chen, Michael J.;
Kress, Benjamin;
Han, Xiaoning;
Moll, Katherine;
Peng, Weiguo;
Ji, Ru-Rong;
Nedergaard, Maiken

Publication type:

Article

Spinal injection of TNF-α-activated astrocytes produces persistent pain symptom mechanical allodynia by releasing monocyte chemoattractant protein-1.

Published in:

Glia (0894-1491), 2010, v. 58, n. 15, p. 1871, doi. 10.1002/glia.21056

By:

Gao, Yong-Jing;
Zhang, Ling;
Ji, Ru-Rong

Publication type:

Article

Induction of C-Fos Expression in the Rostral Medulla of Rats Following Electroacupuncture Stimulation.

Published in:

International Journal of Neuroscience, 1993, v. 72, n. 3/4, p. 183, doi. 10.3109/00207459309024107

By:

Ji, Ru-Rong;
Zhang, Zhi-Wen;
Zhou, Yan;
Zhang, Qin;
Han, Ji-Sheng

Publication type:

Article

Resolvin E1 Inhibits Neuropathic Pain and Spinal Cord Microglial Activation Following Peripheral Nerve Injury.

Published in:

Journal of NeuroImmune Pharmacology, 2013, v. 8, n. 1, p. 37, doi. 10.1007/s11481-012-9394-8

By:

Xu, Zhen-Zhong;
Berta, Temugin;
Ji, Ru-Rong

Publication type:

Article

Stabilization of μ‐opioid receptor facilitates its cellular translocation and signaling.

Published in:

Proteins, 2019, v. 87, n. 10, p. 878, doi. 10.1002/prot.25751

By:

Zhu, Cheng;
Han, Qingjian;
Samoshkin, Alexander;
Convertino, Marino;
Linton, Alexander;
Faison, Edgar M.;
Ji, Ru‐Rong;
Diatchenko, Luda;
Dokholyan, Nikolay V.

Publication type:

Article

Targeting dorsal root ganglia and primary sensory neurons for the treatment of chronic pain: an update.

Published in:

Expert Opinion on Therapeutic Targets, 2023, v. 27, n. 8, p. 665, doi. 10.1080/14728222.2023.2247563

By:

Berta, Temugin;
Strong, Judith A.;
Zhang, Jun-Ming;
Ji, Ru-Rong

Publication type:

Article

Recurrent infections drive persistent bladder dysfunction and pain via sensory nerve sprouting and mast cell activity.

Published in:

Science Immunology, 2024, v. 9, n. 93, p. 1, doi. 10.1126/sciimmunol.adi5578

By:

Hayes, Byron W.;
Choi, Hae Woong;
Rathore, Abhay P.S.;
Bao, Chunjing;
Shi, Jianling;
Huh, Yul;
Kim, Michael W.;
Mencarelli, Andrea;
Bist, Pradeep;
Ng, Lai Guan;
Shi, Changming;
Nho, Joo Hwan;
Kim, Aram;
Yoon, Hana;
Lim, Donghoon;
Hannan, Johanna L.;
Purves, J. Todd;
Hughes Jr., Francis M.;
Ji, Ru-Rong;
Abraham, Soman N.

Publication type:

Article

A mast cell–thermoregulatory neuron circuit axis regulates hypothermia in anaphylaxis.

Published in:

Science Immunology, 2023, v. 8, n. 81, p. 1, doi. 10.1126/sciimmunol.adc9417

By:

Bao, Chunjing;
Chen, Ouyang;
Sheng, Huaxin;
Zhang, Jeffrey;
Luo, Yikai;
Hayes, Byron W.;
Liang, Han;
Liedtke, Wolfgang;
Ji, Ru-Rong;
Abraham, Soman N.

Publication type:

Article

Repurposing cancer drugs identifies kenpaullone which ameliorates pathologic pain in preclinical models via normalization of inhibitory neurotransmission.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26270-3

By:

Yeo, Michele;
Chen, Yong;
Jiang, Changyu;
Chen, Gang;
Wang, Kaiyuan;
Chandra, Sharat;
Bortsov, Andrey;
Lioudyno, Maria;
Zeng, Qian;
Wang, Peng;
Wang, Zilong;
Busciglio, Jorge;
Ji, Ru-Rong;
Liedtke, Wolfgang

Publication type:

Article

STING suppresses bone cancer pain via immune and neuronal modulation.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24867-2

By:

Wang, Kaiyuan;
Donnelly, Christopher R.;
Jiang, Changyu;
Liao, Yihan;
Luo, Xin;
Tao, Xueshu;
Bang, Sangsu;
McGinnis, Aidan;
Lee, Michael;
Hilton, Matthew J.;
Ji, Ru-Rong

Publication type:

Article

Activation of GPR37 in macrophages confers protection against infection-induced sepsis and pain-like behaviour in mice.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-21940-8

By:

Bang, Sangsu;
Donnelly, Christopher R.;
Luo, Xin;
Toro-Moreno, Maria;
Tao, Xueshu;
Wang, Zilong;
Chandra, Sharat;
Bortsov, Andrey V.;
Derbyshire, Emily R.;
Ji, Ru-Rong

Publication type:

Article

Degradable polymeric vehicles for postoperative pain management.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-21438-3

By:

Brigham, Natasha C.;
Ji, Ru-Rong;
Becker, Matthew L.

Publication type:

Article

Spinal Cord Stimulation Attenuates Mechanical Allodynia and Increases Central Resolvin D1 Levels in Rats With Spared Nerve Injury.

Published in:

Frontiers in Physiology, 2021, v. 12, p. 1, doi. 10.3389/fphys.2021.687046

By:

Tao, Xueshu;
Luo, Xin;
Zhang, Tianhe;
Hershey, Brad;
Esteller, Rosana;
Ji, Ru-Rong

Publication type:

Article

Inhibition of mechanical allodynia in neuropathic pain by TLR5-mediated A-fiber blockade.

Published in:

Nature Medicine, 2015, v. 21, n. 11, p. 1326, doi. 10.1038/nm.3978

By:

Xu, Zhen-Zhong;
Kim, Yong Ho;
Bang, Sangsu;
Zhang, Yi;
Berta, Temugin;
Wang, Fan;
Oh, Seog Bae;
Ji, Ru-Rong

Publication type:

Article