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Theoretical Examination Seeking Tangible Physical Meanings of Slopes and Intercepts of Plasma Concentration–Time Relationships in Minimal Physiologically Based Pharmacokinetic Models.
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- AAPS Journal, 2023, v. 25, n. 1, p. 1, doi. 10.1208/s12248-022-00779-x
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- Article
Determination of the Number of Tissue Groups of Kinetically Distinct Transit Time in Whole-Body Physiologically Based Pharmacokinetic (PBPK) Models I: Theoretical Consideration of Bottom-Up Approach of Lumping Tissues in Whole-Body PBPK.
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- AAPS Journal, 2022, v. 24, n. 5, p. 1, doi. 10.1208/s12248-022-00732-y
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- Article
Determination of the Number of Tissue Groups of Kinetically Distinct Transit Time in Whole-Body Physiologically Based Pharmacokinetic (PBPK) Models II: Practical Application of Tissue Lumping Theories for Pharmacokinetics of Various Compounds.
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- AAPS Journal, 2022, v. 24, n. 5, p. 1, doi. 10.1208/s12248-022-00733-x
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- Article
Determinants of Biological Half-Lives and Terminal Slopes in Physiologically Based Pharmacokinetic Systems: Assessment of Limiting Conditions.
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- AAPS Journal, 2022, v. 24, n. 5, p. 1, doi. 10.1208/s12248-022-00739-5
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- Article
Prediction of Pharmacokinetics of IDP-73152 in Humans Using Physiologically-Based Pharmacokinetics.
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- Pharmaceutics, 2022, v. 14, n. 6, p. 1157, doi. 10.3390/pharmaceutics14061157
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- Article
Consideration of Fractional Distribution Parameter f<sub>d</sub> in the Chen and Gross Method for Tissue-to-Plasma Partition Coefficients: Comparison of Several Methods.
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- Pharmaceutical Research, 2022, v. 39, n. 3, p. 463, doi. 10.1007/s11095-022-03211-3
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- Article
Effects of 1α,25-Dihydroxyvitamin D 3 on the Pharmacokinetics of Procainamide and Its Metabolite N-Acetylprocainamide, Organic Cation Transporter Substrates, in Rats with PBPK Modeling Approach.
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- Pharmaceutics, 2021, v. 13, n. 8, p. 1133, doi. 10.3390/pharmaceutics13081133
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- Article
Meta-Assessment of Metformin Absorption and Disposition Pharmacokinetics in Nine Species.
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- Pharmaceuticals (14248247), 2021, v. 14, n. 6, p. 545, doi. 10.3390/ph14060545
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- Article
Development of Physiologically Based Pharmacokinetic Model for Orally Administered Fexuprazan in Humans.
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- Pharmaceutics, 2021, v. 13, n. 6, p. 813, doi. 10.3390/pharmaceutics13060813
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- Article
Investigation of the Factors Responsible for the Poor Oral Bioavailability of Acacetin in Rats: Physicochemical and Biopharmaceutical Aspects.
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- Pharmaceutics, 2021, v. 13, n. 2, p. 175, doi. 10.3390/pharmaceutics13020175
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- Article
Crystal structures of human NSDHL and development of its novel inhibitor with the potential to suppress EGFR activity.
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- Cellular & Molecular Life Sciences, 2021, v. 78, n. 1, p. 207, doi. 10.1007/s00018-020-03490-2
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- Article
Therapeutic Efficacy of ABN401, a Highly Potent and Selective MET Inhibitor, Based on Diagnostic Biomarker Test in MET-Addicted Cancer.
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- Cancers, 2020, v. 12, n. 6, p. 1575, doi. 10.3390/cancers12061575
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- Article
Development and Validation of Analytical Method for SH-1242 in the Rat and Mouse Plasma by Liquid Chromatography/Tandem Mass Spectrometry.
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- Molecules, 2020, v. 25, n. 3, p. 531, doi. 10.3390/molecules25030531
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- Article
Physiologically-Based Pharmacokinetic Modeling for Drug-Drug Interactions of Procainamide and N-Acetylprocainamide with Cimetidine, an Inhibitor of rOCT2 and rMATE1, in Rats.
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- Pharmaceutics, 2019, v. 11, n. 3, p. 108, doi. 10.3390/pharmaceutics11030108
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- Article