Works by Jeffrey, Philip D.

Results: 24

Structural characterization of Tip20p and Dsl1p, subunits of the Dsl1p vesicle tethering complex.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 2, p. 114, doi. 10.1038/nsmb.1548

By:

Tripathi, Arati;
Ren, Yi;
Jeffrey, Philip D;
Hughson, Frederick M

Publication type:

Article

Structural and biochemical insights into the regulation of protein phosphatase 2A by small t antigen of SV40.

Published in:

Nature Structural & Molecular Biology, 2007, v. 14, n. 6, p. 527, doi. 10.1038/nsmb1254

By:

Yu Chen;
Yanhui Xu;
Qing Bao;
Yongna Xing;
Zhu Li;
Zheng Lin;
Stock, Jeffry B.;
Jeffrey, Philip D.;
Yigong Shi

Publication type:

Article

Structural analysis of a rhomboid family intramembrane protease reveals a gating mechanism for substrate entry.

Published in:

Nature Structural & Molecular Biology, 2006, v. 13, n. 12, p. 1084, doi. 10.1038/nsmb1179

By:

Zhuoru Wu;
Nieng Yan;
Liang Feng;
Oberstein, Adam;
Hanchi Yan;
Baker, Rosanna P.;
Lichuan Gu;
Jeffrey, Philip D.;
Urban, Sinisa;
Yigong Shi

Publication type:

Article

A NR2E1‐interacting peptide of LSD1 inhibits the proliferation of brain tumour initiating cells.

Published in:

Cell Proliferation, 2023, v. 56, n. 1, p. 1, doi. 10.1111/cpr.13350

By:

Hu, Rong;
Hameed, Umar Farook Shahul;
Sun, Xiang;
Moorthy, Balakrishnan Shenbaga;
Zhang, Wen;
Jeffrey, Philip D.;
Zhou, Li;
Ma, Xin;
Chen, Fangjin;
Pei, Jianfeng;
Giri, Pankaj K.;
Mou, Yonggao;
Swaminathan, Kunchithapadam;
Yuan, Ping

Publication type:

Article

Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling.

Published in:

Nature Neuroscience, 2004, v. 7, n. 5, p. 501, doi. 10.1038/nn1237

By:

Himanen, Juha-Pekka;
Chumley, Michael J.;
Lackmann, Martin;
Chen Li;
William A. Barton;
Jeffrey, Philip D.;
Vearing, Christopher;
Geleick, Detlef;
Feldheim, David A.;
Boyd, Andrew W.;
Henkemeyer, Mark;
Nikolov, Dimitar B.

Publication type:

Article

Crystal Structures of the Sec1/Munc18 (SM) Protein Vps33, Alone and Bound to the Homotypic Fusion and Vacuolar Protein Sorting (HOPS) Subunit Vps16*.

Published in:

PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0067409

By:

Baker, Richard W.;
Jeffrey, Philip D.;
Hughson, Frederick M.

Publication type:

Article

Structural mechanism of trimeric PR70 PP2A holoenzyme: insights into Cdc6 dephosphorylation.

Published in:

FASEB Journal, 2013, v. 27, p. 1043.2, doi. 10.1096/fasebj.27.1_supplement.1043.2

By:

Wlodarchak, Nathan Joseph;
Guo, Feng;
Satyshur, Kenneth A;
Jiang, Li;
Jeffrey, Philip D;
Sun, Tingwan;
Stanevich, Vitali;
Mumby, Marc C;
Xing, Younga

Publication type:

Article

Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO.

Published in:

PLoS Biology, 2016, v. 14, n. 5, p. 1, doi. 10.1371/journal.pbio.1002464

By:

Boyaci, Hande;
Shah, Tayyab;
Hurley, Amanda;
Kokona, Bashkim;
Li, Zhijie;
Ventocilla, Christian;
Jeffrey, Philip D.;
Semmelhack, Martin F.;
Fairman, Robert;
Bassler, Bonnie L.;
Hughson, Frederick M.

Publication type:

Article

Refined structures of Bobwhite quail lysozyme uncomplexed and complexed with the HyHEL-5 Fab fragment.

Published in:

Proteins, 1996, v. 26, n. 1, p. 55, doi. 10.1002/(SICI)1097-0134(199609)26:1<55::AID-PROT5>3.0.CO;2-F

By:

Chacko, Susan;
Silverton, Enid W.;
Smith-Gill, Sandra J.;
Davies, David R.;
Shick, Kari A.;
Xavier, K. Asish;
Willson, Richard C.;
Jeffrey, Philip D.;
Chang, Chieh Ying Y.;
Sieker, Larry C.;
Sheriff, Steven

Publication type:

Article

Characterization of the backbone dynamics of an anti-digoxin antibody VL domain by inverse detected 1H-15N NMR: Comparisons with X-ray data for the Fab.

Published in:

Proteins, 1993, v. 15, n. 3, p. 290, doi. 10.1002/prot.340150307

By:

Constantine, Keith L.;
Friedrichs, Mark S.;
Goldfarb, Valentina;
Jeffrey, Philip D.;
Sheriff, Steven;
Mueller, Luciano

Publication type:

Article

Conformational Change-Induced Repeat Domain Expansion Regulates Rap Phosphatase Quorum-Sensing Signal Receptors.

Published in:

PLoS Biology, 2013, v. 11, n. 3, p. 1, doi. 10.1371/journal.pbio.1001512

By:

Parashar, Vijay;
Jeffrey, Philip D.;
Neiditch, Matthew B.

Publication type:

Article

Structural Basis of Competitive Recognition of p53 and MDM2 by HAUSP/USP7: Implications for the Regulation of the p53-MDM2 Pathway.

Published in:

PLoS Biology, 2006, v. 4, n. 2, p. e27, doi. 10.1371/journal.pbio.0040027

By:

Hu, Min;
Gu, Lichuan;
Li, Muyang;
Jeffrey, Philip D.;
Gu, Wei;
Shi, Yigong

Publication type:

Article

Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2...

Published in:

Nature, 1996, v. 382, n. 6589, p. 325, doi. 10.1038/382325a0

By:

Russo, Alicia A.;
Jeffrey, Philip D.

Publication type:

Article

Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex.

Published in:

Nature, 1995, v. 376, n. 6538, p. 313, doi. 10.1038/376313a0

By:

Jeffrey, Philip D.;
Russo, Alicia A.

Publication type:

Article

Structure, mechanism and engineering of a nucleotidylyltransferase as a first step toward glycorandomization.

Published in:

Nature Structural Biology, 2001, v. 8, n. 6, p. 545, doi. 10.1038/88618

By:

Barton, William A.;
Lesniak, Jacob;
Biggins, John B.;
Jeffrey, Philip D.;
Jiang, Jiqing;
Rajashankar, K. R.;
Thorson, Jon S.;
Nikolov, Dimitar B.

Publication type:

Article

Structure of the Cul1?Rbx1?Skp1?F boxSkp2 SCF ubiquitin ligase complex.

Published in:

Nature, 2002, v. 416, n. 6882, p. 703, doi. 10.1038/416703a

By:

Zheng, Ning;
Schulman, Brenda A.;
Song, Langzhou;
Miller, Julie J.;
Jeffrey, Philip D.;
Wang, Ping;
Chu, Claire;
Koepp, Deanna M.;
Elledge, Stephen J.;
Pagano, Michele;
Conaway, Ronald C.;
Conaway, Joan W.;
Harper, J. Wade;
Pavletich, Nikola P.

Publication type:

Article

Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex.

Published in:

Nature, 2000, v. 408, n. 6810, p. 381, doi. 10.1038/35042620

By:

Schulman, Brenda A.;
Carrano, Andrea C.;
Jeffrey, Philip D.;
Bowen, Zachary;
Kinnucan, Elspeth R.E.;
Finnin, Michael S.;
Elledge, Stephen J.;
Harper, J. Wade;
Pagano, Michele;
Pavletich, Nikola P.

Publication type:

Article

Structure and mechanism of pyrimidine–pyrimidone (6-4) photoproduct recognition by the Rad4/XPC nucleotide excision repair complex.

Published in:

Nucleic Acids Research, 2019, v. 47, n. 12, p. 6015, doi. 10.1093/nar/gkz359

By:

Paul, Debamita;
Mu, Hong;
Zhao, Hong;
Ouerfelli, Ouathek;
Jeffrey, Philip D;
Broyde, Suse;
Min, Jung-Hyun

Publication type:

Article

The Vibrio cholerae quorum-sensing autoinducer CAI-1: analysis of the biosynthetic enzyme CqsA.

Published in:

Nature Chemical Biology, 2009, v. 5, n. 12, p. 891, doi. 10.1038/nchembio.237

By:

Kelly, Robert C.;
Bolitho, Megan E.;
Higgins, Douglas A.;
Wenyun Lu;
Wai-Leung Ng;
Jeffrey, Philip D.;
Rabinowitz, Joshua D.;
Semmelhack, Martin F.;
Hughson, Frederick M.;
Bassler, Bonnie L.

Publication type:

Article

Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms.

Published in:

Nature, 2008, v. 452, n. 7183, p. 56, doi. 10.1038/nature06636

By:

Yan Xu;
Liang Feng;
Jeffrey, Philip D.;
Yigong Shi;
Morel, François M. M.

Publication type:

Article

Structure of the Ca2+-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylation.

Published in:

Cell Research, 2013, v. 23, n. 7, p. 931, doi. 10.1038/cr.2013.77

By:

Wlodarchak, Nathan;
Guo, Feng;
Satyshur, Kenneth A;
Jiang, Li;
Jeffrey, Philip D;
Sun, Tingwan;
Stanevich, Vitali;
Mumby, Marc C;
Xing, Yongna

Publication type:

Article

The Sec1/Munc18 protein Vps45 holds the Qa-SNARE Tlg2 in an open conformation.

Published in:

eLife, 2020, p. 1, doi. 10.7554/eLife.60724

By:

Eisemann, Travis J.;
Allen, Frederick;
Lau, Kelly;
Shimamura, Gregory R.;
Jeffrey, Philip D.;
Hughson, Frederick M.

Publication type:

Article

Modifying specificity of antidigoxin antibodies using insertional mutagenesis.

Published in:

Protein Science: A Publication of the Protein Society, 2002, v. 11, n. 12, p. 2899, doi. 10.1110/ps.0223402

By:

Krykbaev, Rustem A.;
Tsantili, Panayota;
Jeffrey, Philip D.;
Margolies, Michael N.

Publication type:

Article

Structure and mechanisms of the proteasome-associated deubiquitinating enzyme USP14.

Published in:

EMBO Journal, 2005, v. 24, n. 21, p. 3747, doi. 10.1038/sj.emboj.7600832

By:

Min Hu;
Pingwei Li;
Ling Song;
Jeffrey, Philip D.;
Chenova, Tatiana A.;
Wilkinson, Keith D.;
Cohen, Robert E.;
Yigong Shi

Publication type:

Article

Works by Jeffrey, Philip D.

Structural characterization of Tip20p and Dsl1p, subunits of the Dsl1p vesicle tethering complex.

Structural and biochemical insights into the regulation of protein phosphatase 2A by small t antigen of SV40.

Structural analysis of a rhomboid family intramembrane protease reveals a gating mechanism for substrate entry.

A NR2E1‐interacting peptide of LSD1 inhibits the proliferation of brain tumour initiating cells.

Repelling class discrimination: ephrin-A5 binds to and activates EphB2 receptor signaling.

Crystal Structures of the Sec1/Munc18 (SM) Protein Vps33, Alone and Bound to the Homotypic Fusion and Vacuolar Protein Sorting (HOPS) Subunit Vps16*.

Structural mechanism of trimeric PR70 PP2A holoenzyme: insights into Cdc6 dephosphorylation.

Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO.

Refined structures of Bobwhite quail lysozyme uncomplexed and complexed with the HyHEL-5 Fab fragment.

Characterization of the backbone dynamics of an anti-digoxin antibody V<sub>L</sub> domain by inverse detected <sup>1</sup>H-<sup>15</sup>N NMR: Comparisons with X-ray data for the Fab.

Conformational Change-Induced Repeat Domain Expansion Regulates Rap Phosphatase Quorum-Sensing Signal Receptors.

Structural Basis of Competitive Recognition of p53 and MDM2 by HAUSP/USP7: Implications for the Regulation of the p53-MDM2 Pathway.

Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2...

Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex.

Structure, mechanism and engineering of a nucleotidylyltransferase as a first step toward glycorandomization.

Structure of the Cul1?Rbx1?Skp1?F box<sup>Skp2</sup> SCF ubiquitin ligase complex.

Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex.

Structure and mechanism of pyrimidine–pyrimidone (6-4) photoproduct recognition by the Rad4/XPC nucleotide excision repair complex.

The Vibrio cholerae quorum-sensing autoinducer CAI-1: analysis of the biosynthetic enzyme CqsA.

Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms.

Structure of the Ca<sup>2+</sup>-dependent PP2A heterotrimer and insights into Cdc6 dephosphorylation.

The Sec1/Munc18 protein Vps45 holds the Qa-SNARE Tlg2 in an open conformation.

Modifying specificity of antidigoxin antibodies using insertional mutagenesis.

Structure and mechanisms of the proteasome-associated deubiquitinating enzyme USP14.