Works by Jefferson, Leonard S.

Results: 28

Glucose Availability Regulates Sestrin3 Binding to Hexokinase2 to Affect Glucose‐induced mTORC1 Activation.

Published in:

FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R5903

By:

Roberson, Paul A.;
Welles, Jaclyn E.;
Xu, Dandan;
Kincheloe, Gregory N.;
Jefferson, Leonard S.;
Kimball, Scot R.

Publication type:

Article

An integrative approach to assessing effects of a short-term Western diet on gene expression in rat liver.

Published in:

Frontiers in Endocrinology, 2022, v. 13, p. 1, doi. 10.3389/fendo.2022.1032293

By:

Welles, Jaclyn E.;
Lacko, Holly;
Kawasawa, Yuka Imamura;
Dennis, Michael D.;
Jefferson, Leonard S.;
Kimball, Scot R.

Publication type:

Article

Translational Control of Protein Synthesis: Implications for Understanding Changes in Skeletal Muscle Mass.

Published in:

International Journal of Sport Nutrition & Exercise Metabolism, 2001, v. 11, n. 4, p. S143, doi. 10.1123/ijsnem.11.s1.s143

By:

Jefferson, Leonard S.;
Kimball, Scot R.

Publication type:

Article

Exercise-induced alterations in extracellular signal-regulated kinase 1/2 and mammalian target of rapamycin (mTOR) signalling to regulatory mechanisms of mRNA translation in mouse muscle.

Published in:

Journal of Physiology, 2006, v. 573, n. 2, p. 497, doi. 10.1113/jphysiol.2005.103481

By:

Williamson, David L.;
Kubica, Neil;
Kimball, Scot R.;
Jefferson, Leonard S.

Publication type:

Article

Immediate response of mammalian target of rapamycin (mTOR)-mediated signalling following acute resistance exercise in rat skeletal muscle.

Published in:

Journal of Physiology, 2003, v. 553, n. 1, p. 213, doi. 10.1113/jphysiol.2003.047019

By:

Bolster, Douglas R.;
Kubica, Neil;
Crozier, Stephen J.;
Williamson, David L.;
Farrell, Peter A.;
Kimball, Scot R.;
Jefferson, Leonard S.

Publication type:

Article

Assessment of cell-signaling pathways in the regulation of mammalian target of rapamycin (mTOR) by amino acids in rat adipocytes.

Published in:

Journal of Cellular Biochemistry, 2000, v. 79, n. 3, p. 427, doi. 10.1002/1097-4644(20001201)79:3<427::AID-JCB80>3.0.CO;2-0

By:

Pham, Phuong-Truc T.;
Heydrick, Stan J.;
Fox, Heather L.;
Kimball, Scot R.;
Jefferson,, Leonard S.;
Lynch, Christopher J.

Publication type:

Article

Regulation of amino acid-sensitive TOR signaling by leucine analogues in adipocytes.

Published in:

Journal of Cellular Biochemistry, 2000, v. 77, n. 2, p. 234, doi. 10.1002/(SICI)1097-4644(20000501)77:2<234::AID-JCB7>3.0.CO;2-I

By:

Lynch, Christopher J.;
Fox, Heather L.;
Vary, Thomas C.;
Jefferson, Leonard S.;
Kimball, Scot R.

Publication type:

Article

Regulation of protein synthesis associated with skeletal muscle hypertrophy by insulin-, amino acid- and exercise-induced signalling.

Published in:

Proceedings of the Nutrition Society, 2004, v. 63, n. 2, p. 351, doi. 10.1079/PNS2004355

By:

Bolster, Douglas R.;
Jefferson, Leonard S.;
Kimball, Scot R.

Publication type:

Article

RNA polymerase I transcription in confluent cells: Rb downregulates rDNA transcription during confluence-induced cell cycle arrest.

Published in:

Oncogene, 2000, v. 19, n. 31, p. 3487, doi. 10.1038/sj.onc.1203690

By:

Hannan, Katherine M;
Kennedy, Brian K;
Cavanaugh, Alice H;
Hannan, Ross D;
Hirschler-Laszkiewicz, Iwona;
Jefferson, Leonard S;
Rothblum, Lawrence I

Publication type:

Article

Factors Affecting Secretory Protein Production in Primary Cultures of Rat Hepatocytes.

Published in:

Proceedings of the Society for Experimental Biology & Medicine, 1993, v. 203, n. 1, p. 38, doi. 10.3181/00379727-203-43570

By:

Dahn, Michael S.;
Hsu, Ching Ju;
Lange, M. Patricia;
Kimball, Scot R.;
Jefferson, Leonard S.

Publication type:

Article

RhoA regulates the mechanistic target of rapamycin complex 1 (mTORC1).

Published in:

FASEB Journal, 2013, v. 27, p. 603.3, doi. 10.1096/fasebj.27.1_supplement.603.3

By:

Gordon, Bradley S.;
Kazi, Abid A.;
Coleman, Catherine S.;
Jefferson, Leonard S.;
Chau, Vincent;
Kimball, Scot R.

Publication type:

Article

Molecular Basis for Anabolic Resistance in Disuse Atrophy of Skeletal Muscle.

Published in:

FASEB Journal, 2013, v. 27, p. 1199.3, doi. 10.1096/fasebj.27.1_supplement.1199.3

By:

Kelleher, Andrew Ryan;
Kimball, Scot R;
Dennis, Michael D;
Schilder, Rudolf J;
Jefferson, Leonard S

Publication type:

Article

Hyperglycemia mediates a shift from cap‐dependent to capindependent mRNA translation through a 4E‐BP1 dependent mechanism.

Published in:

FASEB Journal, 2013, v. 27, p. 1080.5, doi. 10.1096/fasebj.27.1_supplement.1080.5

By:

Dennis, Michael D;
Kimball, Scot R;
Jefferson, Leonard S

Publication type:

Article

Repressed elF2B-epsilon expression delays tumor growth in transformed mouse embryonic fibroblasts (TMEF).

Published in:

FASEB Journal, 2007, v. 21, n. 5, p. A651, doi. 10.1096/fasebj.21.5.a651-b

By:

Gallagher, James Walter;
Kubica, Neil;
Kimball, Scot R.;
Jefferson, Leonard S.

Publication type:

Article

Dexamethasone represses signaling through mammalian target of rapamycin (mTOR) in muscle cells by enhancing expression of REDD1.

Published in:

FASEB Journal, 2007, v. 21, n. 5, p. A651, doi. 10.1096/fasebj.21.5.a651-a

By:

Kimball, Scot R.;
Hongmei Wang;
Kubica, Neil;
Ellisen, Leif W.;
Jefferson, Leonard S.

Publication type:

Article

mTORC1-Independent Reduction of Retinal Protein Synthesis in Type 1 Diabetes.

Published in:

Diabetes, 2014, v. 63, n. 9, p. 3077, doi. 10.2337/db14-0235

By:

Fort, Patrice E.;
Losiewicz, Mandy K.;
Pennathur, Subramaniam;
Jefferson, Leonard S.;
Kimball, Scot R.;
Abcouwer, Steven F.;
Gardner, Thomas W.

Publication type:

Article

Hyperglycemia Mediates a Shift From Cap-Dependent to Cap-Independent Translation Via a 4E-BP1--Dependent Mechanism.

Published in:

Diabetes, 2013, v. 62, n. 7, p. 2204, doi. 10.2337/db12-1453

By:

Dennis, Michael D.;
Shenberger, Jeffrey S.;
Stanley, Bruce A.;
Kimball, Scot R.;
Jefferson, Leonard S.

Publication type:

Article

Ablation of 4E-BP1/2 prevents hyperglycemia-mediated induction of VEGF expression in the rodent retina and in Muller cells in culture.

Published in:

2010

By:

Schrufer TL;
Antonetti DA;
Sonenberg N;
Kimball SR;
Gardner TW;
Jefferson LS;
Schrufer, Tabitha L;
Antonetti, David A;
Sonenberg, Nahum;
Kimball, Scot R;
Gardner, Thomas W;
Jefferson, Leonard S

Publication type:

journal article

Ablation of 4E-BP1/2 Prevents Hyperglycemia-Mediated Induction of VEGF Expression in the Rodent Retina and in Müller Cells in Culture.

Published in:

Diabetes, 2010, v. 59, n. 9, p. 2107, doi. 10.2337/db10-0148

By:

Schrufer, Tabitha L.;
Antonetti, David A.;
Sonenberg, Nahum;
Kimball, Scot R.;
Gardner, Thomas W.;
Jefferson, Leonard S.

Publication type:

Article

Rapid Impairment of Retinal Protein Synthesis: A Potential Mechanism for Cellular Dysfunction in Diabetic Retinopathy.

Published in:

Diabetes, 2007, v. 56, p. A216

By:

Fort, Patrice E.;
Singh, Ravi S.;
Losiewicz, Mandy K.;
Reiter, Chad E.;
Freeman, Willard M.;
Gilbert, Kirk A.;
Jefferson, Leonard S.;
Kimball, Scot R.;
Gardner, Thomas W.

Publication type:

Article

Diabetic Retinopathy.

Published in:

Diabetes, 2006, v. 55, n. 9, p. 2401, doi. 10.2337/db05-1635

By:

Antonetti, David A.;
Barber, Alistair J.;
Bronson, Sarah K.;
Freeman, Willard M.;
Gardner, Thomas W.;
Jefferson, Leonard S.;
Kester, Mark;
Kimball, Scot R.;
Krady, J. Kyle;
LaNoue, Kathryn F.;
Norbury, Christopher C.;
Quinn, Patrick G.;
Sandirasegarane, Lakshman;
Simpson, Ian A.

Publication type:

Article

Melatonin represses oxidative stress-induced activation of the MAP kinase and mTOR signaling pathways in H4IIE hepatoma cells through inhibition of Ras.

Published in:

Journal of Pineal Research, 2008, v. 44, n. 4, p. 379, doi. 10.1111/j.1600-079X.2007.00539.x

By:

Kimball, Scot R.;
Abbas, Ahmed;
Jefferson, Leonard S.

Publication type:

Article

Tissue‐specific expression differences in Ras‐related GTP‐binding proteins in male rats.

Published in:

Physiological Reports, 2024, v. 12, n. 3, p. 1, doi. 10.14814/phy2.15928

By:

Kincheloe, Gregory N.;
Roberson, Paul A.;
Jefferson, Leonard S.;
Kimball, Scot R.

Publication type:

Article

Repressors of mTORC1 act to blunt the anabolic response to feeding in the soleus muscle of a cast‐immobilized mouse hindlimb.

Published in:

Physiological Reports, 2018, v. 6, n. 20, p. N.PAG, doi. 10.14814/phy2.13891

By:

Shimkus, Kevin L.;
Jefferson, Leonard S.;
Gordon, Bradley S.;
Kimball, Scot R.

Publication type:

Article

REDD1 enhances protein phosphatase 2A–mediated dephosphorylation of Akt to repress mTORC1 signaling.

Published in:

Science Signaling, 2014, v. 7, n. 335, p. 1, doi. 10.1126/scisignal.2005103

By:

Dennis, Michael D.;
Coleman, Catherine S.;
Berg, Arthur;
Jefferson, Leonard S.;
Kimball, Scot R.

Publication type:

Article

Amino acids as regulators of gene expression.

Published in:

Nutrition & Metabolism, 2004, v. 1, p. 3, doi. 10.1186/1743-7075-1-3

By:

Kimball, Scot R.;
Jefferson, Leonard S.

Publication type:

Article

Protein phosphatase-1 and -2A activities in heart, liver, and skeletal muscle extracts from control and diabetic rats.

Published in:

1984

By:

Foulkes, J. Gordon;
Jefferson, Leonard S.;
Foulkes, J G;
Jefferson, L S

Publication type:

journal article

Role of Insulin in the Regulation of Protein Synthesis.

Published in:

Diabetes, 1980, v. 29, n. 6, p. 487, doi. 10.2337/diab.29.6.487

By:

Jefferson, Leonard S.

Publication type:

Article