Works by Janssen, Josephine M

Results: 19

Adenoviral vector delivery of RNA-guided CRISPR/Cas9 nuclease complexes induces targeted mutagenesis in a diverse array of human cells.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep05105

By:

Maggio, Ignazio;
Holkers, Maarten;
Jin Liu;
Janssen, Josephine M.;
Xiaoyu Chen;
Gonçalves, Manuel A. F. V.

Publication type:

Article

High-Capacity Adenoviral Vectors Permit Robust and Versatile Testing of DMD Gene Repair Tools and Strategies in Human Cells.

Published in:

Cells (2073-4409), 2020, v. 9, n. 4, p. 869, doi. 10.3390/cells9040869

By:

Brescia, Marcella;
Janssen, Josephine M.;
Liu, Jin;
Gonçalves, Manuel A. F. V.

Publication type:

Article

Differential integrity of TALE nuclease genes following adenoviral and lentiviral vector gene transfer into human cells.

Published in:

Nucleic Acids Research, 2013, v. 41, n. 5, p. e63, doi. 10.1093/nar/gks1446

By:

Holkers, Maarten;
Maggio, Ignazio;
Liu, Jin;
Janssen, Josephine M.;
Miselli, Francesca;
Mussolino, Claudio;
Recchia, Alessandra;
Cathomen, Toni;
Gonçalves, Manuel A. F. V.

Publication type:

Article

Development of an AdEasy-based system to produce first- and second-generation adenoviral vectors with tropism for CAR- or CD46-positive cells.

Published in:

Journal of Gene Medicine, 2013, v. 15, n. 1, p. 1, doi. 10.1002/jgm.2687

By:

Janssen, Josephine M.;
Liu, Jin;
Skokan, Jaroslav;
Gonçalves, Manuel A. F. V.;
Vries, Antoine A. F.

Publication type:

Article

Transcription Factor Rational Design Improves Directed Differentiation of Human Mesenchymal Stem Cells Into Skeletal Myocytes.

Published in:

Molecular Therapy, 2011, v. 19, n. 7, p. 1331, doi. 10.1038/mt.2010.308

By:

Gonçalves, Manuel A. F. V.;
Janssen, Josephine M.;
Nguyen, Quynh G.;
Athanasopoulos, Takis;
Hauschka, Stephen D.;
Dickson, George;
de Vries, Antoine A. F.

Publication type:

Article

In trans paired nicking triggers seamless genome editing without double-stranded DNA cutting.

Published in:

Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-00687-1

By:

Xiaoyu Chen;
Janssen, Josephine M.;
Jin Liu;
Maggio, Ignazio;
‘t Jong, Anke E.J.;
Mikkers, Harald M.M.;
Gonçalves, Manuel A.F.V.

Publication type:

Article

Precision genome editing using combinatorial viral vector delivery of CRISPR-Cas9 nucleases and donor DNA constructs.

Published in:

Nucleic Acids Research, 2025, v. 53, n. 2, p. 1, doi. 10.1093/nar/gkae1213

By:

Li, Zhen;
Wang, Xiaoling;
Janssen, Josephine M;
Liu, Jin;
Tasca, Francesca;
Hoeben, Rob C;
Gonçalves, Manuel A F V

Publication type:

Article

Selection-free precise gene repair using high-capacity adenovector delivery of advanced prime editing systems rescues dystrophin synthesis in DMD muscle cells.

Published in:

Nucleic Acids Research, 2024, v. 52, n. 5, p. 2740, doi. 10.1093/nar/gkae057

By:

Wang, Qian;
Capelletti, Sabrina;
Liu, Jin;
Janssen, Josephine M;
Gonçalves, Manuel A F V

Publication type:

Article

Precise homology-directed installation of large genomic edits in human cells with cleaving and nicking high-specificity Cas9 variants.

Published in:

Nucleic Acids Research, 2023, v. 51, n. 7, p. 3465, doi. 10.1093/nar/gkad165

By:

Wang, Qian;
Liu, Jin;
Janssen, Josephine M;
Gonçalves, Manuel A F V

Publication type:

Article

Large-scale genome editing based on high-capacity adenovectors and CRISPR-Cas9 nucleases rescues full-length dystrophin synthesis in DMD muscle cells.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 13, p. 7761, doi. 10.1093/nar/gkac567

By:

Tasca, Francesca;
Brescia, Marcella;
Wang, Qian;
Liu, Jin;
Janssen, Josephine M;
Szuhai, Karoly;
Gonçalves, Manuel A F V

Publication type:

Article

Broadening the reach and investigating the potential of prime editors through fully viral gene-deleted adenoviral vector delivery.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 20, p. 11986, doi. 10.1093/nar/gkab938

By:

Wang, Qian;
Liu, Jin;
Janssen, Josephine M;
Tasca, Francesca;
Mei, Hailiang;
Gonçalves, Manuel A F V

Publication type:

Article

Precise and broad scope genome editing based on high-specificity Cas9 nickases.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 2, p. 1, doi. 10.1093/nar/gkaa1236

By:

Qian Wang;
Jin Liu;
Janssen, Josephine M.;
Le Bouteiller, Marie;
Frock, Richard L.;
Gonçalves, Manuel A. F. V.

Publication type:

Article

Expanding the editable genome and CRISPR–Cas9 versatility using DNA cutting-free gene targeting based on in trans paired nicking.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 2, p. 974, doi. 10.1093/nar/gkz1121

By:

Chen, Xiaoyu;
Tasca, Francesca;
Wang, Qian;
Liu, Jin;
Janssen, Josephine M;
Brescia, Marcella D;
Bellin, Milena;
Szuhai, Karoly;
Kenrick, Josefin;
Frock, Richard L;
Gonçalves, Manuel A F V

Publication type:

Article

Probing the impact of chromatin conformation on genome editing tools.

Published in:

Nucleic Acids Research, 2016, v. 44, n. 13, p. 6482, doi. 10.1093/nar/gkw524

By:

Xiaoyu Chen;
Rinsma, Marrit;
Janssen, Josephine M.;
Liu, Jin;
Maggio, Ignazio;
Gonςalves, Manuel A. F. V.

Publication type:

Article

Selection-free gene repair after adenoviral vector transduction of designer nucleases: rescue of dystrophin synthesis in DMD muscle cell populations.

Published in:

Nucleic Acids Research, 2016, v. 44, n. 3, p. 1449, doi. 10.1093/nar/gkv1540

By:

Maggio, Ignazio;
Stefanucci, Luca;
Janssen, Josephine M.;
Jin Liu;
Xiaoyu Chen;
Mouly, Vincent;
Gonçalves, Manuel A. F. V.

Publication type:

Article

Adenoviral vector DNA for accurate genome editing with engineered nucleases.

Published in:

Nature Methods, 2014, v. 11, n. 10, p. 1051, doi. 10.1038/nmeth.3075

By:

Holkers, Maarten;
Maggio, Ignazio;
Henriques, Sara F D;
Janssen, Josephine M;
Cathomen, Toni;
Gonçalves, Manuel A F V

Publication type:

Article

Rapid and Sensitive Lentivirus Vector-Based Conditional Gene Expression Assay to Monitor and Quantify Cell Fusion Activity.

Published in:

PLoS ONE, 2010, v. 5, n. 6, p. 1, doi. 10.1371/journal.pone.0010954

By:

Gonçalves, Manuel A. F. V.;
Janssen, Josephine M.;
Holkers, Maarten;
de Vries, Antoine A. F.

Publication type:

Article

Adenoviral vectors encoding CRISPR/Cas9 multiplexes rescue dystrophin synthesis in unselected populations of DMD muscle cells.

Published in:

Scientific Reports, 2016, p. 37051, doi. 10.1038/srep37051

By:

Maggio, Ignazio;
Liu, Jin;
Janssen, Josephine M.;
Chen, Xiaoyu;
Gonçalves, Manuel A. F. V.

Publication type:

Article

DNA damage in transcribed genes induces apoptosis via the JNK pathway and the JNK-phosphatase MKP-1.

Published in:

Oncogene, 2005, v. 24, n. 48, p. 7135, doi. 10.1038/sj.onc.1208875

By:

Hamdi, Mohamed;
Kool, Jaap;
Cornelissen-Steijger, Paulien;
Carlotti, Francoise;
Popeijus, Herman E.;
van der Burgt, Corina;
Janssen, Josephine M.;
Yasui, Akira;
Hoeben, Rob C.;
Terleth, Carrol;
Mullenders, Leon H.;
van Dam, Hans

Publication type:

Article