Found: 45
Select item for more details and to access through your institution.
Comment on: Polyglutamine-Expanded Ataxin-3: A Target Engagement Marker for Spinocerebellar Ataxia Type 3 in Peripheral Blood.
- Published in:
- 2022
- By:
- Publication type:
- letter
Phosphorylation Dynamics Regulate Hsp27-Mediated Rescue of Neuronal Plasticity Deficits in Tau Transgenic Mice.
- Published in:
- Journal of Neuroscience, 2010, v. 30, n. 46, p. 15374, doi. 10.1523/JNEUROSCI.3155-10.2010
- By:
- Publication type:
- Article
Massive gliosis induced by interleukin-6 suppresses Aβ deposition in vivo: evidence against inflammation as a driving force for amyloid deposition.
- Published in:
- FASEB Journal, 2010, v. 24, n. 2, p. 548, doi. 10.1096/fj.09-141754
- By:
- Publication type:
- Article
Targeted manipulation of the sortilin–progranulin axis rescues progranulin haploinsufficiency.
- Published in:
- Human Molecular Genetics, 2014, v. 23, n. 6, p. 1467, doi. 10.1093/hmg/ddt534
- By:
- Publication type:
- Article
Ribosomal quality control factors inhibit repeat-associated non-AUG translation from GC-rich repeats.
- Published in:
- Nucleic Acids Research, 2024, v. 52, n. 10, p. 5928, doi. 10.1093/nar/gkae137
- By:
- Publication type:
- Article
CUG initiation and frameshifting enable production of dipeptide repeat proteins from ALS/FTD C9ORF72 transcripts.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-017-02643-5
- By:
- Publication type:
- Article
Serum neurofilament light protein correlates with unfavorable clinical outcomes in hospitalized patients with COVID-19.
- Published in:
- Science Translational Medicine, 2021, v. 13, n. 602, p. 1, doi. 10.1126/scitranslmed.abi7643
- By:
- Publication type:
- Article
Plasma neurofilament light predicts mortality in patients with stroke.
- Published in:
- Science Translational Medicine, 2020, v. 12, n. 569, p. 1, doi. 10.1126/scitranslmed.aay1913
- By:
- Publication type:
- Article
Toward allele-specific targeting therapy and pharmacodynamic marker for spinocerebellar ataxia type 3.
- Published in:
- Science Translational Medicine, 2020, v. 12, n. 566, p. 1, doi. 10.1126/scitranslmed.abb7086
- By:
- Publication type:
- Article
C9orf72 poly(GR) aggregation induces TDP-43 proteinopathy.
- Published in:
- Science Translational Medicine, 2020, v. 12, n. 559, p. 1, doi. 10.1126/scitranslmed.abb3774
- By:
- Publication type:
- Article
Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72-associated amyotrophic lateral sclerosis.
- Published in:
- Science Translational Medicine, 2017, v. 9, n. 383, p. 1, doi. 10.1126/scitranslmed.aai7866
- By:
- Publication type:
- Article
HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases.
- Published in:
- Molecular Neurodegeneration, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13024-024-00718-8
- By:
- Publication type:
- Article
Correction: HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases.
- Published in:
- 2024
- By:
- Publication type:
- Correction Notice
HDGFL2 cryptic proteins report presence of TDP-43 pathology in neurodegenerative diseases.
- Published in:
- Molecular Neurodegeneration, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13024-024-00718-8
- By:
- Publication type:
- Article
TDP-43-regulated cryptic RNAs accumulate in Alzheimer's disease brains.
- Published in:
- Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00646-z
- By:
- Publication type:
- Article
Conserved DNA methylation combined with differential frontal cortex and cerebellar expression distinguishes C9orf72-associated and sporadic ALS, and implicates SERPINA1 in disease.
- Published in:
- Acta Neuropathologica, 2017, v. 134, n. 5, p. 715, doi. 10.1007/s00401-017-1760-4
- By:
- Publication type:
- Article
Aggregation-prone c9FTD/ALS poly(GA) RAN-translated proteins cause neurotoxicity by inducing ER stress.
- Published in:
- Acta Neuropathologica, 2014, v. 128, n. 4, p. 505, doi. 10.1007/s00401-014-1336-5
- By:
- Publication type:
- Article
Antisense transcripts of the expanded <i>C9ORF72</i> hexanucleotide repeat form nuclear RNA foci and undergo repeat-associated non-ATG translation in c9FTD/ALS.
- Published in:
- Acta Neuropathologica, 2013, v. 126, n. 6, p. 829, doi. 10.1007/s00401-013-1192-8
- By:
- Publication type:
- Article
Substrate-targeting γ-secretase modulators.
- Published in:
- Nature, 2008, v. 453, n. 7197, p. 925, doi. 10.1038/nature07055
- By:
- Publication type:
- Article
Clusterin ameliorates tau pathology in vivo by inhibiting fibril formation.
- Published in:
- Acta Neuropathologica Communications, 2020, v. 8, n. 1, p. N.PAG, doi. 10.1186/s40478-020-01079-1
- By:
- Publication type:
- Article
Progranulin regulates neuronal outgrowth independent of Sortilin.
- Published in:
- Molecular Neurodegeneration, 2012, v. 7, n. 1, p. 33, doi. 10.1186/1750-1326-7-33
- By:
- Publication type:
- Article
Chaperone-mediated modulation of tau aggregation correlates with modifications in tau pathology and synaptic plasticity
- Published in:
- 2010
- By:
- Publication type:
- Abstract
Insight into the mechanism of gamma-secretase cleavage: Juxtamembrane amino acids are key to the length of secreted amyloid beta peptide
- Published in:
- 2010
- By:
- Publication type:
- Abstract
P2-347: BRI2 (ITM2B) inhibits Aβ deposition
- Published in:
- 2008
- By:
- Publication type:
- Abstract
P1-052: Somatic brain transgenic TDP-43 mice
- Published in:
- 2008
- By:
- Publication type:
- Abstract
Systematic analysis of dark and camouflaged genes reveals disease-relevant genes hiding in plain sight.
- Published in:
- Genome Biology, 2019, v. 20, n. 1, p. N.PAG, doi. 10.1186/s13059-019-1707-2
- By:
- Publication type:
- Article
The Pathological Phenotypes of Human TDP-43 Transgenic Mouse Models Are Independent of Downregulation of Mouse Tdp-43.
- Published in:
- PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0069864
- By:
- Publication type:
- Article
Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia.
- Published in:
- 2020
- By:
- Publication type:
- journal article
Tau exhibits unique seeding properties in globular glial tauopathy.
- Published in:
- Acta Neuropathologica Communications, 2019, v. 7, n. 1, p. N.PAG, doi. 10.1186/s40478-019-0691-9
- By:
- Publication type:
- Article
Enhanced phosphorylation of T153 in soluble tau is a defining biochemical feature of the A152T tau risk variant.
- Published in:
- Acta Neuropathologica Communications, 2019, v. 7, n. 1, p. N.PAG, doi. 10.1186/s40478-019-0661-2
- By:
- Publication type:
- Article
Loss of Tmem106b is unable to ameliorate frontotemporal dementia-like phenotypes in an AAV mouse model of <italic>C9ORF72</italic>-repeat induced toxicity.
- Published in:
- Acta Neuropathologica Communications, 2018, v. 6, n. 1, p. N.PAG, doi. 10.1186/s40478-018-0545-x
- By:
- Publication type:
- Article
Astrocyte-derived clusterin suppresses amyloid formation in vivo.
- Published in:
- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. N.PAG, doi. 10.1186/s13024-020-00416-1
- By:
- Publication type:
- Article
Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency.
- Published in:
- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. 1, doi. 10.1186/s13024-020-00369-5
- By:
- Publication type:
- Article
Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy.
- Published in:
- Molecular Neurodegeneration, 2019, v. 14, n. 1, p. N.PAG, doi. 10.1186/s13024-019-0310-z
- By:
- Publication type:
- Article
Long-read sequencing across the C9orf72 ‘GGGGCC’ repeat expansion: implications for clinical use and genetic discovery efforts in human disease.
- Published in:
- Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0274-4
- By:
- Publication type:
- Article
Correction: TDP-43 and other hnRNPs regulate cryptic exon inclusion of a key ALS/FTD risk gene, UNC13A.
- Published in:
- 2023
- By:
- Publication type:
- Correction Notice
TDP-43 and other hnRNPs regulate cryptic exon inclusion of a key ALS/FTD risk gene, UNC13A.
- Published in:
- PLoS Biology, 2023, v. 21, n. 3, p. 1, doi. 10.1371/journal.pbio.3002028
- By:
- Publication type:
- Article
Investigating the Pathogenic Interplay of Alpha-Synuclein, Tau, and Amyloid Beta in Lewy Body Dementia: Insights from Viral-Mediated Overexpression in Transgenic Mouse Models.
- Published in:
- Biomedicines, 2023, v. 11, n. 10, p. 2863, doi. 10.3390/biomedicines11102863
- By:
- Publication type:
- Article
Aß40 displays amyloidogenic properties in the non-transgenic mouse brain but does not exacerbate Aß42 toxicity in Drosophila.
- Published in:
- Alzheimer's Research & Therapy, 2020, v. 12, n. 1, p. N.PAG, doi. 10.1186/s13195-020-00698-z
- By:
- Publication type:
- Article
TMEM106B core deposition associates with TDP-43 pathology and is increased in risk SNP carriers for frontotemporal dementia.
- Published in:
- Science Translational Medicine, 2024, v. 16, n. 730, p. 1, doi. 10.1126/scitranslmed.adf9735
- By:
- Publication type:
- Article
Interferon-γ induces progressive nigrostriatal degeneration and basal ganglia calcification.
- Published in:
- Nature Neuroscience, 2011, v. 14, n. 6, p. 694, doi. 10.1038/nn.2829
- By:
- Publication type:
- Article
Repetitive element transcripts are elevated in the brain of C9orf72 ALS/FTLD patients.
- Published in:
- Human Molecular Genetics, 2017, v. 26, n. 17, p. 3421, doi. 10.1093/hmg/ddx233
- By:
- Publication type:
- Article
TDP-43 functions within a network of hnRNP proteins to inhibit the production of a truncated human SORT1 receptor.
- Published in:
- Human Molecular Genetics, 2016, v. 25, n. 3, p. 534, doi. 10.1093/hmg/ddv491
- By:
- Publication type:
- Article
Tau deposition drives neuropathological, inflammatory and behavioral abnormalities independently of neuronal loss in a novel mouse model.
- Published in:
- Human Molecular Genetics, 2015, v. 24, n. 21, p. 6198, doi. 10.1093/hmg/ddv336
- By:
- Publication type:
- Article
Tau and neurofilament light‐chain as fluid biomarkers in spinocerebellar ataxia type 3.
- Published in:
- European Journal of Neurology, 2022, v. 29, n. 8, p. 2439, doi. 10.1111/ene.15373
- By:
- Publication type:
- Article