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Immune Monitoring of Mycophenolate Mofetil Activity in Healthy Volunteers Using Ex Vivo T Cell Function Assays.
Published in:
Pharmaceutics, 2023, v. 15, n. 6, p. 1635, doi. 10.3390/pharmaceutics15061635
By:
- in 't Veld, Aliede E.;
- Jansen, Manon A. A.;
- de Kam, Marieke L.;
- Yavuz, Yalҫin;
- Moes, Dirk Jan A. R.;
- Oudhoff, Kathalijne A.;
- van Poelgeest, Mariette I. E.;
- Burggraaf, Jacobus;
- Moerland, Matthijs
Publication type:
Article
Monitoring of Ex Vivo Cyclosporin a Activity in Healthy Volunteers Using T Cell Function Assays in Relation to Whole Blood and Cellular Pharmacokinetics.
Published in:
Pharmaceutics, 2022, v. 14, n. 9, p. N.PAG, doi. 10.3390/pharmaceutics14091958
By:
- in 't Veld, Aliede E.;
- Jansen, Manon A. A.;
- Huisman, Bertine W.;
- Schoonakker, Mascha;
- de Kam, Marieke L.;
- Moes, Dirk Jan A. R.;
- van Poelgeest, Mariëtte I. E.;
- Burggraaf, Jacobus;
- Moerland, Matthijs
Publication type:
Article
Immunomodulating effects of the single bacterial strain therapy EDP1815 on innate and adaptive immune challenge responses — a randomized, placebo-controlled clinical trial.
Published in:
Immunologic Research, 2024, v. 72, n. 4, p. 776, doi. 10.1007/s12026-024-09484-7
By:
- Eveleens Maarse, Boukje C.;
- Ronner, Micha N.;
- Jansen, Manon A. A.;
- Niemeyer-van der Kolk, Tessa;
- in 't Veld, Aliede E.;
- Klaassen, Erica S.;
- Ahmad, Saira;
- Itano, Andrea;
- McHale, Duncan;
- Moerland, Matthijs
Publication type:
Article
Immunosuppression by hydroxychloroquine: mechanistic proof in in vitro experiments but limited systemic activity in a randomized placebo-controlled clinical pharmacology study.
Published in:
Immunologic Research, 2023, v. 71, n. 4, p. 617, doi. 10.1007/s12026-023-09367-3
By:
- in 't Veld, Aliede E.;
- Grievink, Hendrika W.;
- van der Plas, Johan L.;
- Eveleens Maarse, Boukje C.;
- van Kraaij, Sebastiaan J. W.;
- Woutman, Tess D.;
- Schoonakker, Mascha;
- Klarenbeek, Naomi B.;
- de Kam, Marieke L.;
- Kamerling, Ingrid M. C.;
- Jansen, Manon A. A.;
- Moerland, Matthijs
Publication type:
Article
Heat Shock Proteins Can Be Surrogate Autoantigens for Induction of Antigen Specific Therapeutic Tolerance in Rheumatoid Arthritis.
Published in:
Frontiers in Immunology, 2019, p. 1, doi. 10.3389/fimmu.2019.00279
By:
- van Eden, Willem;
- Jansen, Manon A. A.;
- Ludwig, Irene S.;
- Leufkens, Paul;
- van der Goes, Marlies C.;
- van Laar, Jacob M.;
- Broere, Femke
Publication type:
Article
The Immunomodulatory Potential of tolDCs Loaded with Heat Shock Proteins.
Published in:
Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.01690
By:
- van Eden, Willem;
- Jansen, Manon A. A.;
- de Wolf, A. Charlotte M. T.;
- Ludwig, Irene S.;
- Leufkens, Paul;
- Broere, Femke
Publication type:
Article
The Enigma of Heat Shock Proteins in Immune Tolerance.
Published in:
Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.01599
By:
- van Eden, Willem;
- Jansen, Manon A. A.;
- Ludwig, Irene;
- van Kooten, Peter;
- van der Zee, Ruurd;
- Broere, Femke
Publication type:
Article
Hydroxychloroquine Effects on TLR Signalling: Underexposed but Unneglectable in COVID-19.
Published in:
2021
By:
- in 't Veld, Aliede E.;
- Jansen, Manon A. A.;
- Ciere, Luuk C. A.;
- Moerland, Matthijs
Publication type:
journal article
Erratum to "Hydroxychloroquine Effects on TLR Signalling: Underexposed but Unneglectable in COVID-19".
Published in:
2021
By:
- in 't Veld, Aliede E.;
- Jansen, Manon A. A.;
- Ciere, Luuk C. A.;
- Moerland, Matthijs
Publication type:
corrected article
Hydroxychloroquine Effects on TLR Signalling: Underexposed but Unneglectable in COVID-19.
Published in:
Journal of Immunology Research, 2021, p. 1, doi. 10.1155/2021/6659410
By:
- in 't Veld, Aliede E.;
- Jansen, Manon A. A.;
- Ciere, Luuk C. A.;
- Moerland, Matthijs
Publication type:
Article
Matured Tolerogenic Dendritic Cells Effectively Inhibit Autoantigen Specific CD4<sup>+</sup> T Cells in a Murine Arthritis Model.
Published in:
Frontiers in Immunology, 2019, p. 1, doi. 10.3389/fimmu.2019.02068
By:
- Jansen, Manon A. A.;
- Spiering, Rachel;
- Ludwig, Irene S.;
- van Eden, Willem;
- Hilkens, Catharien M. U.;
- Broere, Femke
Publication type:
Article
Effect of hydroxychloroquine on the cardiac ventricular repolarization: A randomized clinical trial.
Published in:
British Journal of Clinical Pharmacology, 2022, v. 88, n. 3, p. 1054, doi. 10.1111/bcp.15013
By:
- Eveleens Maarse, Boukje C.;
- Graff, Claus;
- Kanters, Jørgen K.;
- van Esdonk, Michiel J.;
- Kemme, Michiel J. B.;
- in 't Veld, Aliede E.;
- Jansen, Manon A. A.;
- Moerland, Matthijs;
- Gal, Pim
Publication type:
Article
Intradermal lipopolysaccharide challenge as an acute in vivo inflammatory model in healthy volunteers.
Published in:
British Journal of Clinical Pharmacology, 2022, v. 88, n. 2, p. 680, doi. 10.1111/bcp.14999
By:
- Buters, Thomas P.;
- Hameeteman, Pieter W.;
- Jansen, Iris M. E.;
- van Hindevoort, Floris C.;
- ten Voorde, Wouter;
- Florencia, Edwin;
- Osse, Michelle;
- de Kam, Marieke L.;
- Grievink, Hendrika W.;
- Schoonakker, Mascha;
- Patel, Amit A.;
- Yona, Simon;
- Gilroy, Derek W.;
- Lubberts, Erik;
- Damman, Jeffrey;
- Feiss, Gary;
- Rissmann, Robert;
- Jansen, Manon A. A.;
- Burggraaf, Jacobus;
- Moerland, Matthijs
Publication type:
Article
Correction: Wind et al. Topical Bimiralisib Shows Meaningful Cutaneous Drug Levels in Healthy Volunteers and Mycosis Fungoides Patients but No Clinical Activity in a First-in-Human, Randomized Controlled Trial. Cancers 2022, 14 , 1510.
Published in:
2023
By:
- Wind, Selinde S.;
- Jansen, Manon A. A.;
- Rijsbergen, Melanie;
- van Esdonk, Michiel J.;
- Ziagkos, Dimitrios;
- Cheng, Wing C.;
- Niemeyer-van der Kolk, Tessa;
- Korsten, John;
- Gruszka, Agnieszka;
- Schmitz-Rohmer, Debora;
- Bonnel, David;
- Legouffe, Raphael;
- Barré, Florian;
- Bekkenk, Marcel W.;
- de Haas, Ellen R. M.;
- Quint, Koen D.;
- Schnidar, Harald;
- Rolli, Melanie;
- Streefkerk, Henk Johan;
- Burggraaf, Jacobus
Publication type:
Correction Notice
Topical Bimiralisib Shows Meaningful Cutaneous Drug Levels in Healthy Volunteers and Mycosis Fungoides Patients but No Clinical Activity in a First-in-Human, Randomized Controlled Trial.
Published in:
Cancers, 2022, v. 14, n. 6, p. 1510, doi. 10.3390/cancers14061510
By:
- Wind, Selinde S.;
- Jansen, Manon A. A.;
- Rijsbergen, Melanie;
- van Esdonk, Michiel J.;
- Ziagkos, Dimitrios;
- Cheng, Wing C.;
- Niemeyer-van der Kolk, Tessa;
- Korsten, John;
- Gruszka, Agnieszka;
- Schmitz-Rohmer, Debora;
- Bonnel, David;
- Legouffe, Raphael;
- Barré, Florian;
- Bekkenk, Marcel W.;
- de Haas, Ellen R. M.;
- Quint, Koen D.;
- Rolli, Melanie;
- Streefkerk, Henk Johan;
- Burggraaf, Jacobus;
- Vermeer, Maarten H.
Publication type:
Article
Identifying and prioritizing educational content from a malpractice claims database for clinical reasoning education in the vocational training of general practitioners.
Published in:
Advances in Health Sciences Education, 2023, v. 28, n. 3, p. 893, doi. 10.1007/s10459-022-10194-8
By:
- van Sassen, Charlotte G. M.;
- van den Berg, Pieter J.;
- Mamede, Silvia;
- Knol, Lilian;
- Eikens-Jansen, Manon P.;
- van den Broek, Walter W.;
- Bindels, Patrick J. E.;
- Zwaan, Laura
Publication type:
Article
Oral prednisolone suppresses skin inflammation in a healthy volunteer imiquimod challenge model.
Published in:
Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1197650
By:
- Assil, Salma;
- Buters, Thomas P.;
- Hameeteman, Pieter W.;
- Hallard, Charlie;
- Treijtel, Nicoline;
- Niemeyer - Van der Kolk, Tessa;
- de Kam, Marieke L.;
- Florencia, Edwin F. I. I. I.;
- Prens, Errol P.;
- van Doorn, Martijn B. A.;
- Rissmann, Robert;
- Klarenbeek, Naomi B.;
- Jansen, Manon A. A.;
- Moerland, Matthijs
Publication type:
Article
Clinical, Cellular, and Molecular Effects of Corticosteroids on the Response to Intradermal Lipopolysaccharide Administration in Healthy Volunteers.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 4, p. 964, doi. 10.1002/cpt.2516
By:
- Buters, Thomas P.;
- Hameeteman, Pieter W.;
- Jansen, Iris M.E.;
- van Hindevoort, Floris C.;
- ten Voorde, Wouter;
- Grievink, Hendrika W.;
- Schoonakker, Mascha;
- de Kam, Marieke L.;
- Gilroy, Derek W.;
- Feiss, Gary;
- Rissmann, Robert;
- Jansen, Manon A.A.;
- Burggraaf, Jacobus;
- Moerland, Matthijs
Publication type:
Article
The oral IRAK4 inhibitors zabedosertib and BAY1830839 suppress local and systemic immune responses in a randomized trial in healthy male volunteers.
Published in:
CTS: Clinical & Translational Science, 2024, v. 17, n. 3, p. 1, doi. 10.1111/cts.13771
By:
- Jodl, Stefan J.;
- ten Voorde, Wouter;
- Klein, Stefan;
- Wagenfeld, Andrea;
- Zollmann, Frank S.;
- Feldmüller, Maximilian;
- Klarenbeek, Naomi B.;
- de Bruin, Digna T.;
- Jansen, Manon A. A.;
- Rissmann, Robert;
- Rohde, Beate;
- Moerland, Matthijs
Publication type:
Article
Targeting of tolerogenic dendritic cells towards heat-shock proteins: a novel therapeutic strategy for autoimmune diseases?
Published in:
Immunology, 2018, v. 153, n. 1, p. 51, doi. 10.1111/imm.12811
By:
- Jansen, Manon A. A.;
- Spiering, Rachel;
- Broere, Femke;
- van Laar, Jacob M.;
- Isaacs, John D.;
- van Eden, Willem;
- Hilkens, Catharien M. U.
Publication type:
Article
Generation of the First TCR Transgenic Mouse with CD4<sup>+</sup> T Cells Recognizing an Anti-inflammatory Regulatory T Cell-Inducing Hsp70 Peptide.
Published in:
Frontiers in Immunology, 2016, p. 1, doi. 10.3389/fimmu.2016.00090
By:
- Jansen, Manon A. A.;
- van Herwijnen, Martijn J. C.;
- van Kooten, Peter J. S.;
- Hoek, Aad;
- van der Zee, Ruurd;
- van Eden, Willem;
- Broere, Femke
Publication type:
Article
Targeting of tolerogenic dendritic cells to heat-shock proteins in inflammatory arthritis.
Published in:
2019
By:
- Spiering, Rachel;
- Jansen, Manon A. A.;
- Wood, Matthew J.;
- Fath, Anshorulloh A.;
- Eltherington, Oliver;
- Anderson, Amy E.;
- Pratt, Arthur G.;
- van Eden, Willem;
- Isaacs, John D.;
- Broere, Femke;
- Hilkens, Catharien M. U.
Publication type:
journal article

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