Works by James Lu

Results: 64

Genome-Wide Identification of Rare and Common Variants Driving Triglyceride Levels in a Nevada Population.

Published in:

Frontiers in Genetics, 2021, v. 11, p. N.PAG, doi. 10.3389/fgene.2021.639418

By:

Read, Robert W.;
Schlauch, Karen A.;
Lombardi, Vincent C.;
Cirulli, Elizabeth T.;
Washington, Nicole L.;
Lu, James T.;
Grzymski, Joseph J.

Publication type:

Article

Current Status and Future Directions: The Application of Artificial Intelligence/Machine Learning for Precision Medicine.

Published in:

Clinical Pharmacology & Therapeutics, 2024, v. 115, n. 4, p. 673, doi. 10.1002/cpt.3152

By:

Naik, Kunal;
Goyal, Rahul K.;
Foschini, Luca;
Chak, Choi Wai;
Thielscher, Christian;
Zhu, Hao;
Lu, James;
Lehár, Joseph;
Pacanoswki, Michael A.;
Terranova, Nadia;
Mehta, Neha;
Korsbo, Niklas;
Fakhouri, Tala;
Liu, Qi;
Gobburu, Jogarao

Publication type:

Article

Machine Learning‐Based Quantification of Patient Factors Impacting Remission in Patients With Ulcerative Colitis: Insights from Etrolizumab Phase III Clinical Trials.

Published in:

Clinical Pharmacology & Therapeutics, 2024, v. 115, n. 4, p. 815, doi. 10.1002/cpt.3076

By:

Harun, Rashed;
Lu, James;
Kassir, Nastya;
Zhang, Wenhui

Publication type:

Article

Artificial Intelligence for Quantitative Modeling in Drug Discovery and Development: An Innovation and Quality Consortium Perspective on Use Cases and Best Practices.

Published in:

Clinical Pharmacology & Therapeutics, 2024, v. 115, n. 4, p. 658, doi. 10.1002/cpt.3053

By:

Terranova, Nadia;
Renard, Didier;
Shahin, Mohamed H.;
Menon, Sujatha;
Cao, Youfang;
Hop, Cornelis E.C.A.;
Hayes, Sean;
Madrasi, Kumpal;
Stodtmann, Sven;
Tensfeldt, Thomas;
Vaddady, Pavan;
Ellinwood, Nicholas;
Lu, James

Publication type:

Article

Comprehensive Allele Genotyping in Critical Pharmacogenes Reduces Residual Clinical Risk in Diverse Populations.

Published in:

Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 3, p. 759, doi. 10.1002/cpt.2279

By:

Luo, Shishi;
Jiang, Ruomu;
Grzymski, Joseph J.;
Lee, William;
Lu, James T.;
Washington, Nicole L.

Publication type:

Article

Future strategic challenges for hotel industry in Asia*.

Published in:

Asia Pacific Journal of Tourism Research, 2005, v. 10, n. 1, p. 133, doi. 10.1080/1094166052000341305

By:

Lu, James

Publication type:

Article

Machine Learning for Exposure-Response Analysis: Methodological Considerations and Confirmation of Their Importance via Computational Experimentations.

Published in:

Pharmaceutics, 2023, v. 15, n. 5, p. 1381, doi. 10.3390/pharmaceutics15051381

By:

Harun, Rashed;
Yang, Eric;
Kassir, Nastya;
Zhang, Wenhui;
Lu, James

Publication type:

Article

Drugs affecting renin-angiotensin-aldosterone system and the cancer risk: A meta-analysis of nested case-control studies.

Published in:

Pakistan Journal of Pharmaceutical Sciences, 2021, v. 34, n. 1, p. 35, doi. 10.36721/PJPS.2021.34.1.REG.035-039.1

By:

Liu Dong-mei;
Zhang Wei;
Hao Guang-jun;
James Lu;
Han Jian-lun;
Zhang Jian

Publication type:

Article

SARS-CoV-2 Antiviral Prescribing Gaps Among Nonhospitalized High-Risk Adults.

Published in:

Clinical Infectious Diseases, 2024, v. 78, n. 6, p. 1531, doi. 10.1093/cid/ciad796

By:

Levy, Matthew E;
Burrows, Evanette;
Chilunda, Vanessa;
Pawloski, Pamala A;
Heaton, Phillip R;
Grzymski, Joseph;
Goldman, Jason D;
McEwen, Lisa M;
Wyman, Dana;
Rossi, Andrew Dei;
Dai, Hang;
Isaksson, Magnus;
Washington, Nicole L;
Basler, Tracy;
Tsan, Kevin;
Nguyen, Jason;
Ramirez, Jimmy;
Sandoval, Efren;
Lee, William;
Lu, James

Publication type:

Article

Toxic lead exposure via an unusual source: New BC reporting regulations may prevent similar cases.

Published in:

British Columbia Medical Journal, 2019, v. 61, n. 1, p. 41

By:

McVea, David;
Lu, James;
Pudek, Morris;
Sehmer, Benjamin;
Kosatsky, Tom

Publication type:

Article

Promoting active commuting in British Columbia.

Published in:

British Columbia Medical Journal, 2017, v. 59, n. 9, p. 449

By:

McVea, David;
Peterson, Emily;
Lu, James

Publication type:

Article

Responding to climate change in BC: What can physicians do?

Published in:

British Columbia Medical Journal, 2017, v. 59, n. 4, p. 227

By:

Peterson, Emily;
Lu, James

Publication type:

Article

Loss of DDRGK1 modulates SOX9 ubiquitination in spondyloepimetaphyseal dysplasia.

Published in:

2017

By:

Egunsola, Adetutu T.;
Yangjin Bae;
Ming-Ming Jiang;
Liu, David S.;
Yuqing Chen-Evenson;
Bertin, Terry;
Shan Chen;
Lu, James T.;
Nevarez, Lisette;
Magal, Nurit;
Raas-Rothschild, Annick;
Swindell, Eric C.;
Cohn, Daniel H.;
Gibbs, Richard A.;
Campeau, Philippe M.;
Shohat, Mordechai;
Lee, Brendan H.;
Bae, Yangjin;
Jiang, Ming-Ming;
Chen-Evenson, Yuqing

Publication type:

journal article

Inverse problems from biomedicine.

Published in:

Journal of Mathematical Biology, 2013, v. 67, n. 1, p. 143, doi. 10.1007/s00285-012-0523-z

By:

Lu, James;
August, Elias;
Koeppl, Heinz

Publication type:

Article

Recording stereoscopic 3D neurosurgery with a head-mounted 3D camera system.

Published in:

British Journal of Neurosurgery, 2015, v. 29, n. 3, p. 371, doi. 10.3109/02688697.2014.997664

By:

Lee, Brian;
Chen, Brian R.;
Chen, Beverly B.;
Lu, James Y.;
Giannotta, Steven L.

Publication type:

Article

The SBML ODE Solver Library: a native API for symbolic and fast numerical analysis of reaction networks.

Published in:

Bioinformatics, 2006, v. 22, n. 11, p. 1406, doi. 10.1093/bioinformatics/btl086

By:

Rainer Machné;
Andrew Finney;
Stefan Müller;
James Lu;
Stefanie Widder;
Christoph Flamm

Publication type:

Article

Enabling Ontology Based Semantic Queries in Biomedical Database Systems.

Published in:

International Journal of Semantic Computing, 2014, v. 8, n. 1, p. 67, doi. 10.1142/S1793351X14500032

By:

Zheng, Shuai;
Wang, Fusheng;
Lu, James

Publication type:

Article

Comprehensive Environmental Investigation at Former Industrial/Petroleum Underground Storage Tank Sites in Long Beach, CA: A Forensic Perspective.

Published in:

Environmental Forensics, 2015, v. 16, n. 1, p. 27, doi. 10.1080/15275922.2014.991007

By:

Kim, Daeik;
Lu, James C.;
Park, Joon-Seok

Publication type:

Article

Incomplete Penetrance of Population-Based Genetic Screening Results in Electronic Health Record.

Published in:

Frontiers in Genetics, 2022, v. 13, p. 1, doi. 10.3389/fgene.2022.866169

By:

Elhanan, Gai;
Kiser, Daniel;
Neveux, Iva;
Dabe, Shaun;
Bolze, Alexandre;
Metcalf, William J.;
Lu, James T.;
Grzymski, Joseph J.

Publication type:

Article

A case study in the meta-reasoning procedure ND.

Published in:

Journal of Experimental & Theoretical Artificial Intelligence, 2003, v. 15, n. 1, p. 47, doi. 10.1080/0952813021000028621

By:

Lu, James J.;
Rosenthal, Jeffrey S.;
Shaffer, Andrew E.

Publication type:

Article

A bifunctional nociceptin and mu opioid receptor agonist is analgesic without opioid side effects in nonhuman primates.

Published in:

Science Translational Medicine, 2018, v. 10, n. 456, p. 1, doi. 10.1126/scitranslmed.aar3483

By:

Ding, Huiping;
Kiguchi, Norikazu;
Yasuda, Dennis;
Daga, Pankaj R.;
Polgar, Willma E.;
Lu, James J.;
Czoty, Paul W.;
Kishioka, Shiroh;
Zaveri, Nurulain T.;
Ko, Mei-Chuan

Publication type:

Article

Explainable deep learning for tumor dynamic modeling and overall survival prediction using Neural-ODE.

Published in:

NPJ Systems Biology & Applications, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41540-023-00317-1

By:

Laurie, Mark;
Lu, James

Publication type:

Article

Dosage and Dose Schedule Screening of Drug Combinations in Agent-Based Models Reveals Hidden Synergies.

Published in:

Frontiers in Physiology, 2016, p. 1, doi. 10.3389/fphys.2015.00398

By:

de Andrade e Sousa, Lisa C. Barros;
Kühn, Clemens;
Tyc, Katarzyna M.;
Klipp, Edda;
Bhardwaj, Anshu;
Lu, James;
Sorokin, Anatoly

Publication type:

Article

Personal Exposure to Fine Particulate Air Pollution among Brick Workers in Nepal.

Published in:

Atmosphere, 2023, v. 14, n. 12, p. 1783, doi. 10.3390/atmos14121783

By:

Johnston, James D.;
Collingwood, Scott C.;
LeCheminant, James D.;
Peterson, Neil E.;
Reynolds, Paul R.;
Arroyo, Juan A.;
South, Andrew J.;
Farnsworth, Clifton B.;
Chartier, Ryan T.;
Layton, Lindsey N.;
Lu, James H.;
Penrod, Marli S.;
Sanjel, Seshananda;
Beard, John D.

Publication type:

Article

Chemical Composition of PM 2.5 in Wood Fire and LPG Cookstove Homes of Nepali Brick Workers.

Published in:

Atmosphere, 2021, v. 12, n. 7, p. 911, doi. 10.3390/atmos12070911

By:

Johnston, James D.;
Beard, John D.;
Montague, Emma J.;
Sanjel, Seshananda;
Lu, James H.;
McBride, Haley;
Weber, Frank X.;
Chartier, Ryan T.

Publication type:

Article

Exome sequencing identifies a novel homozygous mutation in the phosphate transporter SLC34A1 in hypophosphatemia and nephrocalcinosis.

Published in:

2014

By:

Rajagopal, Abbhirami;
Braslavsky, Débora;
Lu, James T;
Kleppe, Soledad;
Clément, Florencia;
Cassinelli, Hamilton;
Liu, David S;
Liern, Jose Miguel;
Vallejo, Graciela;
Bergadá, Ignacio;
Gibbs, Richard A;
Campeau, Phillipe M;
Lee, Brendan H

Publication type:

journal article

Multiscale Mathematical Model of Drug-Induced Proximal Tubule Injury: Linking Urinary Biomarkers to Epithelial Cell Injury and Renal Dysfunction.

Published in:

Toxicological Sciences, 2018, v. 162, n. 1, p. 200, doi. 10.1093/toxsci/kfx239

By:

Gebremichael, Yeshitila;
Lu, James;
Shankaran, Harish;
Helmlinger, Gabriel;
Mettetal, Jerome;
Hallow, K Melissa

Publication type:

Article

Drug Delivery–mediated Control of RNA Immunostimulation.

Published in:

Molecular Therapy, 2009, v. 17, n. 9, p. 1555, doi. 10.1038/mt.2009.147

By:

Nguyen, David N..;
Chen, Steve C.-Y.;
Lu, James;
Goldberg, Michael;
Kim, Phillip;
Sprague, Andrew;
Novobrantseva, Tatiana;
Sherman, Jennifer;
Shulga-Morskaya, Svetlana;
de Fougerolles, Antonin;
Jianzhu Chen;
Langer, Robert;
Anderson, Daniel G.

Publication type:

Article

795. RNA Interference of Influenza Virus Infection.

Published in:

Molecular Therapy, 2006, v. 13, p. S308, doi. 10.1016/j.ymthe.2006.08.884

By:

Jianzhu Chen;
Qing Ge;
Lu, James;
Herman, Eisen N.

Publication type:

Article

Wildfire smoke: Health effects and protective strategies.

Published in:

UBC Medical Journal, 2018, v. 10, n. 1, p. 5

By:

McVea, David A.;
James Lu

Publication type:

Article

Comparison of Deterministic and Statistical Models for Water Quality Compliance Forecasting in the San Joaquin River Basin, California.

Published in:

Water (20734441), 2021, v. 13, n. 19, p. 2661, doi. 10.3390/w13192661

By:

Quinn, Nigel W. T.;
Tansey, Michael K.;
Lu, James

Publication type:

Article

Large Language Models and Their Applications in Drug Discovery and Development: A Primer.

Published in:

CTS: Clinical & Translational Science, 2025, v. 18, n. 4, p. 1, doi. 10.1111/cts.70205

By:

Lu, James;
Choi, Keunwoo;
Eremeev, Maksim;
Gobburu, Jogarao;
Goswami, Srijib;
Liu, Qi;
Mo, Gary;
Musante, Cynthia J.;
Shahin, Mohamed H.

Publication type:

Article

AI‐Driven Applications in Clinical Pharmacology and Translational Science: Insights From the ASCPT 2024 AI Preconference.

Published in:

CTS: Clinical & Translational Science, 2025, v. 18, n. 4, p. 1, doi. 10.1111/cts.70203

By:

Shahin, Mohamed H.;
Desai, Prashant;
Terranova, Nadia;
Guan, Yuanfang;
Helikar, Tomáš;
Lobentanzer, Sebastian;
Liu, Qi;
Lu, James;
Madhavan, Subha;
Mo, Gary;
Musuamba, Flora T.;
Podichetty, Jagdeep T.;
Shen, Jie;
Xie, Lei;
Wiens, Mathew;
Musante, Cynthia J.

Publication type:

Article

Integrating real‐world data and machine learning: A framework to assess covariate importance in real‐world use of alternative intravenous dosing regimens for atezolizumab.

Published in:

CTS: Clinical & Translational Science, 2024, v. 17, n. 11, p. 1, doi. 10.1111/cts.70077

By:

Vora, Bianca;
Jindal, Ashutosh;
Velasquez, Erick;
Lu, James;
Wu, Benjamin

Publication type:

Article

Population pharmacokinetics and CD20 binding dynamics for mosunetuzumab in relapsed/refractory B‐cell non‐Hodgkin lymphoma.

Published in:

CTS: Clinical & Translational Science, 2024, v. 17, n. 6, p. 1, doi. 10.1111/cts.13825

By:

Bender, Brendan;
Li, Chi‐Chung;
Marchand, Mathilde;
Turner, David C.;
Li, Feifei;
Vadhavkar, Shweta;
Wang, Bei;
Deng, Rong;
Lu, James;
Jin, Jin;
Li, Chunze;
Yin, Shen;
Wei, Michael;
Chanu, Pascal

Publication type:

Article

Genetic counseling, 2030: An on‐demand service tailored to the needs of a price conscious, genetically literate, and busy world.

Published in:

Journal of Genetic Counseling, 2019, v. 28, n. 2, p. 456, doi. 10.1002/jgc4.1123

By:

Rashkin, Misha D.;
Bowes, Johnathan;
Dunaway, Keith;
Dhaliwal, Jasmine;
Loomis, Erick;
Riffle, Stephen;
Washington, Nicole L.;
Ziegler, Chris;
Lu, James;
Levin, Elissa

Publication type:

Article

Inverse bifurcation analysis: application to simple gene systems.

Published in:

Algorithms for Molecular Biology, 2006, v. 1, p. 11, doi. 10.1186/1748-7188-1-11

By:

Lu, James;
Engl, Heinz W.;
Schuster, Peter

Publication type:

Article

Mapping behavioral specifications to model parameters in synthetic biology.

Published in:

BMC Bioinformatics, 2013, v. 14, n. Suppl 10, p. 1, doi. 10.1186/1471-2105-14-S10-S9

By:

Koeppl, Heinz;
Hafner, Marc;
Lu, James

Publication type:

Article

An <i>In-Silico</i> Model of Lipoprotein Metabolism and Kinetics for the Evaluation of Targets and Biomarkers in the Reverse Cholesterol Transport Pathway.

Published in:

PLoS Computational Biology, 2014, v. 10, n. 3, p. 1, doi. 10.1371/journal.pcbi.1003509

By:

Lu, James;
Hübner, Katrin;
Nanjee, M. Nazeem;
Brinton, Eliot A.;
Mazer, Norman A.

Publication type:

Article

Interdisciplinary investigation of contaminants fate and transport at a former UST site (10-year case study).

Published in:

Environmental Earth Sciences, 2011, v. 64, n. 1, p. 277, doi. 10.1007/s12665-011-0979-y

By:

Daeik Kim;
Wonho Song;
Lu, James C.

Publication type:

Article

Characterizing linkage disequilibrium and evaluating imputation power of human genomic insertion-deletion polymorphisms.

Published in:

Genome Biology, 2012, v. 13, n. 2, p. 1, doi. 10.1186/gb-2012-13-2-r15

By:

Lu, James T.;
Yi Wang;
Gibbs, Richard A.;
Fuli Yu

Publication type:

Article

Corner fracture type spondylometaphyseal dysplasia: Overlap with type II collagenopathies.

Published in:

American Journal of Medical Genetics. Part A, 2017, v. 173, n. 3, p. 733, doi. 10.1002/ajmg.a.38059

By:

Machol, Keren;
Jain, Mahim;
Almannai, Mohammed;
Orand, Thibault;
Lu, James T.;
Tran, Alyssa;
Chen, Yuqing;
Schlesinger, Alan;
Gibbs, Richard;
Bonafe, Luisa;
Campos‐Xavier, Ana Belinda;
Unger, Sheila;
Superti‐Furga, Andrea;
Lee, Brendan H.;
Campeau, Philippe M.;
Burrage, Lindsay C.

Publication type:

Article

Adult presentation of X-linked Conradi-Hünermann-Happle syndrome.

Published in:

American Journal of Medical Genetics. Part A, 2015, v. 167A, n. 6, p. 1309, doi. 10.1002/ajmg.a.36899

By:

Posey, Jennifer E.;
Burrage, Lindsay C.;
Campeau, Philippe M.;
Lu, James T.;
Eble, Tanya N.;
Kratz, Lisa;
Schlesinger, Alan E.;
Gibbs, Richard A.;
Lee, Brendan H.;
Nagamani, Sandesh C.S.

Publication type:

Article

Osteogenesis imperfecta without features of type V caused by a mutation in the IFITM 5 gene.

Published in:

Journal of Bone & Mineral Research, 2013, v. 28, n. 11, p. 2333, doi. 10.1002/jbmr.1983

By:

Grover, Monica;
Campeau, Philippe M;
Lietman, Caressa Dee;
Lu, James T;
Gibbs, Richard A;
Schlesinger, Alan E;
Lee, Brendan H

Publication type:

Article

Phenotypic Variability of Osteogenesis Imperfecta Type V Caused by an IFITM 5 Mutation.

Published in:

Journal of Bone & Mineral Research, 2013, v. 28, n. 7, p. 1523, doi. 10.1002/jbmr.1891

By:

Shapiro, Jay R;
Lietman, Caressa;
Grover, Monica;
Lu, James T;
Nagamani, Sandesh CS;
Dawson, Brian C;
Baldridge, Dustin M;
Bainbridge, Matthew N;
Cohn, Dan H;
Blazo, Maria;
Roberts, Timothy T;
Brennen, Feng-Shu;
Wu, Yimei;
Gibbs, Richard A;
Melvin, Pamela;
Campeau, Philippe M;
Lee, Brendan H

Publication type:

Article

Controlled vocabularies and semantics in systems biology.

Published in:

Molecular Systems Biology, 2011, v. 7, n. 1, p. 1, doi. 10.1038/msb.2011.77

By:

Courtot, Mélanie;
Juty, Nick;
Knüpfer, Christian;
Waltemath, Dagmar;
Zhukova, Anna;
Dräger, Andreas;
Dumontier, Michel;
Finney, Andrew;
Golebiewski, Martin;
Hastings, Janna;
Hoops, Stefan;
Keating, Sarah;
Kell, Douglas B;
Kerrien, Samuel;
Lawson, James;
Lister, Allyson;
Lu, James;
Machne, Rainer;
Mendes, Pedro;
Pocock, Matthew

Publication type:

Article

Geospatial indicators of exposure, sensitivity, and adaptive capacity to assess neighbourhood variation in vulnerability to climate change-related health hazards.

Published in:

2021

By:

Yu, Jessica;
Castellani, Kaitlin;
Forysinski, Krista;
Gustafson, Paul;
Lu, James;
Peterson, Emily;
Tran, Martino;
Yao, Angela;
Zhao, Jingxuan;
Brauer, Michael

Publication type:

journal article

An in vitro quantitative systems pharmacology approach for deconvolving mechanisms of drug-induced, multilineage cytopenias.

Published in:

PLoS Computational Biology, 2020, v. 16, n. 7, p. 1, doi. 10.1371/journal.pcbi.1007620

By:

Wilson, Jennifer L.;
Lu, Dan;
Corr, Nick;
Fullerton, Aaron;
Lu, James

Publication type:

Article

Predicting overall survival from tumor dynamics metrics using parametric statistical and machine learning models: application to patients with RET-altered solid tumors.

Published in:

Frontiers in Artificial Intelligence, 2024, p. 1, doi. 10.3389/frai.2024.1412865

By:

Velasquez, Erick;
Kassir, Nastya;
Cheeti, Sravanthi;
Kuruvilla, Denison;
Sane, Rucha;
Dang, Steve;
Miles, Dale;
Lu, James

Publication type:

Article

Enacting Asian American Transformations: An Inter-ethnic Perspective.

Published in:

1998

By:

Lu, James

Publication type:

Literary Criticism