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Tau assemblies do not behave like independently acting prion-like particles in mouse neural tissue.
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- Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01141-6
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- Article
Trim-Away ubiquitinates and degrades lysine-less and N-terminally acetylated substrates.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-37504-x
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- Article
The type‐I interferon response potentiates seeded tau aggregation and exacerbates tau pathology.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 2, p. 1013, doi. 10.1002/alz.13493
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- Article
The cytosolic antibody receptor TRIM21 is required for effective tau immunotherapy.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076800
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- Publication type:
- Article
A novel and robust method for counting components within bio-molecular complexes using fluorescence microscopy and statistical modelling.
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- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-20506-y
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- Publication type:
- Article
Sequences in the cytoplasmic tail of SARS-CoV-2 Spike facilitate expression at the cell surface and syncytia formation.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25589-1
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- Article
A functional assay for serum detection of antibodies against SARS‐CoV‐2 nucleoprotein.
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- EMBO Journal, 2021, v. 40, n. 17, p. 1, doi. 10.15252/embj.2021108588
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- Article
Viral nucleoprotein antibodies activate TRIM21 and induce T cell immunity.
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- EMBO Journal, 2021, v. 40, n. 5, p. 1, doi. 10.15252/embj.2020106228
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- Publication type:
- Article
Antibody and DNA sensing pathways converge to activate the inflammasome during primary human macrophage infection.
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- EMBO Journal, 2019, v. 38, n. 21, p. N.PAG, doi. 10.15252/embj.2018101365
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- Article
Diverse HIV viruses are targeted by a conformationally dynamic antiviral.
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- Nature Structural & Molecular Biology, 2012, v. 19, n. 4, p. 411, doi. 10.1038/nsmb.2253
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- Article
Active site remodeling switches HIV specificity of antiretroviral TRIMCyp.
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- Nature Structural & Molecular Biology, 2009, v. 16, n. 10, p. 1036, doi. 10.1038/nsmb.1667
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- Article
Corrigendum: Antibody-antigen kinetics constrain intracellular humoral immunity.
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- Scientific Reports, 2017, p. 45418, doi. 10.1038/srep45418
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- Article
Antibody-antigen kinetics constrain intracellular humoral immunity.
- Published in:
- Scientific Reports, 2016, p. 37457, doi. 10.1038/srep37457
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- Article
A lysine ring in HIV capsid pores coordinates IP6 to drive mature capsid assembly.
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- PLoS Pathogens, 2021, v. 17, n. 2, p. 1, doi. 10.1371/journal.ppat.1009164
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- Publication type:
- Article
Furin cleavage of SARS-CoV-2 Spike promotes but is not essential for infection and cell-cell fusion.
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- PLoS Pathogens, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.ppat.1009246
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- Publication type:
- Article
IP6‐stabilised HIV capsids evade cGAS/STING‐mediated host immune sensing.
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- EMBO Reports, 2023, v. 24, n. 5, p. 1, doi. 10.15252/embr.202256275
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- Publication type:
- Article
TRIM21—From Intracellular Immunity to Therapy.
- Published in:
- Frontiers in Immunology, 2019, p. 1, doi. 10.3389/fimmu.2019.02049
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- Publication type:
- Article
A tri-ionic anchor mechanism drives Ube2N-specific recruitment and K63-chain ubiquitination in TRIM ligases.
- Published in:
- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-12388-y
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- Publication type:
- Article
Single‐dose immunisation with a multimerised SARS‐CoV‐2 receptor binding domain (RBD) induces an enhanced and protective response in mice.
- Published in:
- FEBS Letters, 2021, v. 595, n. 18, p. 2323, doi. 10.1002/1873-3468.14171
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- Publication type:
- Article
TRIM21: a cytosolic Fc receptor with broad antibody isotype specificity.
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- Immunological Reviews, 2015, v. 268, n. 1, p. 328, doi. 10.1111/imr.12363
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- Publication type:
- Article
Pharmacologic hyperstabilisation of the HIV-1 capsid lattice induces capsid failure.
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- eLife, 2024, p. 1, doi. 10.7554/eLife.83605
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- Article
Human coronaviruses activate and hijack the host transcription factor HSF1 to enhance viral replication.
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- Cellular & Molecular Life Sciences, 2024, v. 81, n. 1, p. 1, doi. 10.1007/s00018-024-05370-5
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- Article
Intracellular antibody-bound pathogens stimulate immune signaling via the Fc receptor TRIM21.
- Published in:
- Nature Immunology, 2013, v. 14, n. 4, p. 327, doi. 10.1038/ni.2548
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- Publication type:
- Article
Potent TRIM21 and complement-dependent intracellular antiviral immunity requires the IgG3 hinge.
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- Science Immunology, 2022, v. 7, n. 70, p. 1, doi. 10.1126/sciimmunol.abj1640
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- Publication type:
- Article
TRIM7 Restricts Coxsackievirus and Norovirus Infection by Detecting the C-Terminal Glutamine Generated by 3C Protease Processing.
- Published in:
- Viruses (1999-4915), 2022, v. 14, n. 8, p. 1610, doi. 10.3390/v14081610
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- Publication type:
- Article
IP6 Regulation of HIV Capsid Assembly, Stability, and Uncoating.
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- Viruses (1999-4915), 2018, v. 10, n. 11, p. 640, doi. 10.3390/v10110640
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- Publication type:
- Article
TRIM21 Promotes cGAS and RIG-I Sensing of Viral Genomes during Infection by Antibody-Opsonized Virus.
- Published in:
- PLoS Pathogens, 2015, v. 11, n. 10, p. 1, doi. 10.1371/journal.ppat.1005253
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- Publication type:
- Article
Host Cofactors and Pharmacologic Ligands Share an Essential Interface in HIV-1 Capsid That Is Lost upon Disassembly.
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- PLoS Pathogens, 2014, v. 10, n. 10, p. 1, doi. 10.1371/journal.ppat.1004459
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- Article
CPSF6 Defines a Conserved Capsid Interface that Modulates HIV-1 Replication.
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- PLoS Pathogens, 2012, v. 8, n. 8, p. 1, doi. 10.1371/journal.ppat.1002896
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- Publication type:
- Article
HIV-1 Capsid-Cyclophilin Interactions Determine Nuclear Import Pathway, Integration Targeting and Replication Efficiency.
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- PLoS Pathogens, 2011, v. 7, n. 12, p. 1, doi. 10.1371/journal.ppat.1002439
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- Article
HIV Integration Targeting: A Pathway Involving Transportin-3 and the Nuclear Pore Protein RanBP2.
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- PLoS Pathogens, 2011, v. 7, n. 3, p. 1, doi. 10.1371/journal.ppat.1001313
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- Article
Characterization of host proteins interacting with the lymphocytic choriomeningitis virus L protein.
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- PLoS Pathogens, 2017, v. 13, n. 12, p. 1, doi. 10.1371/journal.ppat.1006758
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- Article
HIV-1 evades innate immune recognition through specific cofactor recruitment.
- Published in:
- Nature, 2013, v. 503, n. 7476, p. 402, doi. 10.1038/nature12769
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- Publication type:
- Article
Antibodies targeting the Crimean-Congo Hemorrhagic Fever Virus nucleoprotein protect via TRIM21.
- Published in:
- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-53362-7
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- Publication type:
- Article
HIV-1 adapts to lost IP6 coordination through second-site mutations that restore conical capsid assembly.
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- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-51971-w
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- Publication type:
- Article
Intracellular antibody-mediated immunity and the role of TRIM21.
- Published in:
- BioEssays, 2011, v. 33, n. 11, p. 803, doi. 10.1002/bies.201100093
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- Article
Publisher Correction: Acute and rapid degradation of endogenous proteins by Trim-Away.
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- 2019
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- Publication type:
- Correction Notice
Acute and rapid degradation of endogenous proteins by Trim-Away.
- Published in:
- Nature Protocols, 2018, v. 13, n. 10, p. 2149, doi. 10.1038/s41596-018-0028-3
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- Publication type:
- Article
The specificity of cross-reactivity: Promiscuous antibody binding involves specific hydrogen bonds rather than nonspecific hydrophobic stickiness.
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- Protein Science: A Publication of the Protein Society, 2003, v. 12, n. 10, p. 2183, doi. 10.1110/ps.03172703
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- Article
Catalytic and binding poly-reactivities shared by two unrelated proteins: The potential role of promiscuity in enzyme evolution.
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- Protein Science: A Publication of the Protein Society, 2001, v. 10, n. 12, p. 2600, doi. 10.1110/ps.14601
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- Publication type:
- Article
Acetylation regulates Cyclophilin A catalysis, immunosuppression and HIV isomerization.
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- Nature Chemical Biology, 2010, v. 6, n. 5, p. 331, doi. 10.1038/nchembio.342
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- Article
Intracellular antibody immunity and its applications.
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- PLoS Pathogens, 2020, v. 16, n. 8, p. 1, doi. 10.1371/journal.ppat.1008657
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- Publication type:
- Article
Intracellular neutralisation of rotavirus by VP6-specific IgG.
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- PLoS Pathogens, 2020, v. 16, n. 8, p. 1, doi. 10.1371/journal.ppat.1008732
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- Publication type:
- Article
RING domains act as both substrate and enzyme in a catalytic arrangement to drive self-anchored ubiquitination.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-21443-6
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- Publication type:
- Article
Characterization of innate immune viral sensors in patients following allogeneic hematopoietic stem cell transplantation.
- Published in:
- Innate Immunity, 2018, v. 24, n. 2, p. 112, doi. 10.1177/1753425918757898
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- Publication type:
- Article
HIV-1 capsid undergoes coupled binding and isomerization by the nuclear pore protein NUP358.
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- Retrovirology, 2013, v. 10, n. 1, p. 1, doi. 10.1186/1742-4690-10-81
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- Publication type:
- Article
The V86M mutation in HIV-1 capsid confers resistance to TRIM5a by abrogation of cyclophilin A-dependent restriction and enhancement of viral nuclear import.
- Published in:
- Retrovirology, 2013, v. 10, n. 1, p. 1, doi. 10.1186/1742-4690-10-25
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- Publication type:
- Article