Works by Jamei, Masoud

Results: 55

A mechanistic pharmacokinetic model to assess modified oral drug bioavailability post bariatric surgery in morbidly obese patients: interplay between CYP3A gut wall metabolism, permeability and dissolution.

Published in:

Journal of Pharmacy & Pharmacology, 2012, v. 64, n. 7, p. 1008, doi. 10.1111/j.2042-7158.2012.01538.x

By:

Darwich, Adam S.;
Pade, Devendra;
Ammori, Basil J.;
Jamei, Masoud;
Ashcroft, Darren M.;
Rostami-Hodjegan, Amin

Publication type:

Article

Application of Physiologically Based Pharmacokinetic (PBPK) Modeling Within a Bayesian Framework to Identify Poor Metabolizers of Efavirenz (PM), Using a Test Dose of Efavirenz.

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00247

By:

Chetty, Manoranjenni;
Cain, Theresa;
Wedagedera, Janak;
Rostami-Hodjegan, Amin;
Jamei, Masoud

Publication type:

Article

Predicting drug-drug interactions: application of physiologically based pharmacokinetic models under a systems biology approach.

Published in:

Expert Review of Clinical Pharmacology, 2013, v. 6, n. 2, p. 143, doi. 10.1586/ECP.13.4

By:

Yeo, Karen Rowland;
Jamei, Masoud;
Rostami-Hodjegan, Amin

Publication type:

Article

Modeling and predicting drug pharmacokinetics in patients with renal impairment.

Published in:

Expert Review of Clinical Pharmacology, 2011, v. 4, n. 2, p. 261, doi. 10.1586/ecp.10.143

By:

Yeo, Karen Rowland;
Aarabi, Mohsen;
Jamei, Masoud;
Rostami-Hodjegan, Amin

Publication type:

Article

Physiologically-based pharmacokinetic modeling to predict drug-drug interaction of enzalutamide with combined P-gp and CYP3A substrates.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2023, v. 50, n. 5, p. 365, doi. 10.1007/s10928-023-09867-7

By:

Otsuka, Yukio;
Poondru, Srinivasu;
Bonate, Peter L.;
Rose, Rachel H.;
Jamei, Masoud;
Ushigome, Fumihiko;
Minematsu, Tsuyoshi

Publication type:

Article

Prediction of maternal pharmacokinetics using physiologically based pharmacokinetic models: assessing the impact of the longitudinal changes in the activity of CYP1A2, CYP2D6 and CYP3A4 enzymes during pregnancy.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2020, v. 47, n. 4, p. 361, doi. 10.1007/s10928-020-09711-2

By:

Abduljalil, Khaled;
Pansari, Amita;
Jamei, Masoud

Publication type:

Article

Quantitative approach for cardiac risk assessment and interpretation in tuberculosis drug development.

Published in:

Journal of Pharmacokinetics & Pharmacodynamics, 2018, v. 45, n. 3, p. 457, doi. 10.1007/s10928-018-9580-2

By:

Polak, Sebastian;
Romero, Klaus;
Berg, Alexander;
Patel, Nikunjkumar;
Jamei, Masoud;
Hermann, David;
Hanna, Debra

Publication type:

Article

A Physiologically Based Pharmacokinetic Model Relates the Subcutaneous Bioavailability of Monoclonal Antibodies to the Saturation of FcRn-Mediated Recycling in Injection-Site-Draining Lymph Nodes.

Published in:

Antibodies (2073-4468), 2024, v. 13, n. 3, p. 70, doi. 10.3390/antib13030070

By:

Stader, Felix;
Liu, Cong;
Derbalah, Abdallah;
Momiji, Hiroshi;
Pan, Xian;
Gardner, Iain;
Jamei, Masoud;
Sepp, Armin

Publication type:

Article

Prediction of the pharmacokinetics, pharmacodynamics, and efficacy of a monoclonal antibody, using a physiologically based pharmacokinetic FcRn model.

Published in:

Frontiers in Immunology, 2015, v. 5, p. 1, doi. 10.3389/fimmu.2014.00670

By:

Chetty, Manoranjenni;
Linzhong Li;
Rose, Rachel;
Machavaram, Krishna;
Jamei, Masoud;
Rostami-Hodjegan, Amin;
Gardner, Iain;
Frenkel, Dan;
Olive, Daniel

Publication type:

Article

Early assessment of proarrhythmic risk of drugs using the in vitro data and single-cell-based in silico models: proof of concept.

Published in:

Toxicology Mechanisms & Methods, 2017, v. 27, n. 2, p. 88, doi. 10.1080/15376516.2016.1256460

By:

Abbasi, Mitra;
Small, Ben G.;
Patel, Nikunjkumar;
Jamei, Masoud;
Polak, Sebastian

Publication type:

Article

Multi‐phase multi‐layer mechanistic dermal absorption (MPML MechDermA) model to predict local and systemic exposure of drug products applied on skin.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2022, v. 11, n. 8, p. 1060, doi. 10.1002/psp4.12814

By:

Patel, Nikunjkumar;
Clarke, James F.;
Salem, Farzaneh;
Abdulla, Tariq;
Martins, Frederico;
Arora, Sumit;
Tsakalozou, Eleftheria;
Hodgkinson, Arran;
Arjmandi‐Tash, Omid;
Cristea, Sinziana;
Ghosh, Priyanka;
Alam, Khondoker;
Raney, Sam G.;
Jamei, Masoud;
Polak, Sebastian

Publication type:

Article

Population PBPK modeling using parametric and nonparametric methods of the Simcyp Simulator, and Bayesian samplers.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2022, v. 11, n. 6, p. 755, doi. 10.1002/psp4.12787

By:

Wedagedera, Janak R.;
Afuape, Anthonia;
Chirumamilla, Siri Kalyan;
Momiji, Hiroshi;
Leary, Robert;
Dunlavey, Mike;
Matthews, Richard;
Abduljalil, Khaled;
Jamei, Masoud;
Bois, Frederic Y.

Publication type:

Article

Development of physiologically‐based pharmacokinetic models for standard of care and newer tuberculosis drugs.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 11, p. 1382, doi. 10.1002/psp4.12707

By:

Humphries, Helen;
Almond, Lisa;
Berg, Alexander;
Gardner, Iain;
Hatley, Oliver;
Pan, Xian;
Small, Ben;
Zhang, Mian;
Jamei, Masoud;
Romero, Klaus

Publication type:

Article

Prediction of drug concentrations in milk during breastfeeding, integrating predictive algorithms within a physiologically‐based pharmacokinetic model.

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 8, p. 878, doi. 10.1002/psp4.12662

By:

Abduljalil, Khaled;
Pansari, Amita;
Ning, Jia;
Jamei, Masoud

Publication type:

Article

Where Do PBPK Models Stand in Pharmacometrics and Systems Pharmacology?

Published in:

CPT: Pharmacometrics & Systems Pharmacology, 2020, v. 9, n. 2, p. 75, doi. 10.1002/psp4.12493

By:

Jamei, Masoud

Publication type:

Article

Pharmacokinetics under the COVID‐19 storm.

Published in:

British Journal of Clinical Pharmacology, 2023, v. 89, n. 1, p. 158, doi. 10.1111/bcp.14668

By:

Pilla Reddy, Venkatesh;
El‐Khateeb, Eman;
Jo, Heeseung;
Giovino, Natalie;
Lythgoe, Emily;
Sharma, Shringi;
Tang, Weifeng;
Jamei, Masoud;
Rastomi‐Hodjegan, Amin

Publication type:

Article

A pregnancy physiologically based pharmacokinetic (p- PBPK) model for disposition of drugs metabolized by CYP1A2, CYP2D6 and CYP3A4.

Published in:

British Journal of Clinical Pharmacology, 2012, v. 74, n. 5, p. 873, doi. 10.1111/j.1365-2125.2012.04363.x

By:

Gaohua, Lu;
Abduljalil, Khaled;
Jamei, Masoud;
Johnson, Trevor N.;
Rostami-Hodjegan, Amin

Publication type:

Article

Static Versus Dynamic Model Predictions of Competitive Inhibitory Metabolic Drug–Drug Interactions via Cytochromes P450: One Step Forward and Two Steps Backwards: Static versus Dynamic Models to Predict DDIs via CYP: I. Tiryannik et al.

Published in:

Clinical Pharmacokinetics, 2025, v. 64, n. 1, p. 155, doi. 10.1007/s40262-024-01457-1

By:

Tiryannik, Ivan;
Heikkinen, Aki T.;
Gardner, Iain;
Onasanwo, Anthonia;
Jamei, Masoud;
Polasek, Thomas M.;
Rostami-Hodjegan, Amin

Publication type:

Article

Prediction of Maternal and Fetal Acyclovir, Emtricitabine, Lamivudine, and Metformin Concentrations during Pregnancy Using a Physiologically Based Pharmacokinetic Modeling Approach.

Published in:

2022

By:

Abduljalil, Khaled;
Pansari, Amita;
Ning, Jia;
Jamei, Masoud

Publication type:

journal article

Authors' Reply to Völler et al: "Comment on: Preterm Physiologically Based Pharmacokinetic Model, Part I and Part II".

Published in:

2021

By:

Abduljalil, Khaled;
Pan, Xian;
Pansari, Amita;
Jamei, Masoud;
Johnson, Trevor N.

Publication type:

Letter

Fetal Physiologically Based Pharmacokinetic Models: Systems Information on Fetal Blood Components and Binding Proteins.

Published in:

2020

By:

Abduljalil, Khaled;
Jamei, Masoud;
Johnson, Trevor N.

Publication type:

journal article

Preterm Physiologically Based Pharmacokinetic Model. Part II: Applications of the Model to Predict Drug Pharmacokinetics in the Preterm Population.

Published in:

2020

By:

Abduljalil, Khaled;
Pan, Xian;
Pansari, Amita;
Jamei, Masoud;
Johnson, Trevor N.

Publication type:

journal article

A Preterm Physiologically Based Pharmacokinetic Model. Part I: Physiological Parameters and Model Building.

Published in:

2020

By:

Abduljalil, Khaled;
Pan, Xian;
Pansari, Amita;
Jamei, Masoud;
Johnson, Trevor N.

Publication type:

journal article

Fetal Physiologically Based Pharmacokinetic Models: Systems Information on the Growth and Composition of Fetal Organs.

Published in:

2019

By:

Abduljalil, Khaled;
Jamei, Masoud;
Johnson, Trevor N.

Publication type:

journal article

Prediction of Voriconazole Non-linear Pharmacokinetics Using a Paediatric Physiologically Based Pharmacokinetic Modelling Approach.

Published in:

Clinical Pharmacokinetics, 2015, v. 54, n. 5, p. 567, doi. 10.1007/s40262-015-0247-5

By:

Johnson, Trevor;
Salem, Farzaneh;
Jamei, Masoud;
Rostami-Hodjegan, Amin

Publication type:

Article

Predicting Nonlinear Pharmacokinetics of Omeprazole Enantiomers and Racemic Drug Using Physiologically Based Pharmacokinetic Modeling and Simulation: Application to Predict Drug/Genetic Interactions.

Published in:

Pharmaceutical Research, 2014, v. 31, n. 8, p. 1919, doi. 10.1007/s11095-013-1293-z

By:

Wu, Fang;
Gaohua, Lu;
Zhao, Ping;
Jamei, Masoud;
Huang, Shiew-Mei;
Bashaw, Edward;
Lee, Sue-Chih

Publication type:

Article

Implications of mechanism-based inhibition of CYP2D6 for the pharmacokinetics and toxicity of MDMA.

Published in:

Journal of Psychopharmacology, 2006, v. 20, n. 6, p. 842, doi. 10.1177/0269881106065907

By:

Jiansong Yang;
Jamei, Masoud;
Heydari, Amir;
Yeo, Karen R.;
De la Torre, Rafael;
Farré, Magí;
Tucker, Geoffrey T.;
Rostami-Hodjegan, Amin

Publication type:

Article

Cytokine Dynamics in Action: A Mechanistic Approach to Assess Interleukin 6 Related Therapeutic Protein‐Drug–Disease Interactions.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 5, p. 1369, doi. 10.1002/cpt.3560

By:

Pan, Xian;
Gill, Katherine L.;
Pansari, Amita;
Hatley, Oliver;
Curry, Liam;
Jamei, Masoud;
Gardner, Iain

Publication type:

Article

Incorporation and Performance Verification of Hepatic Portal Blood Flow Shunting in Minimal and Full PBPK Models of Liver Cirrhosis.

Published in:

Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 6, p. 1264, doi. 10.1002/cpt.3032

By:

Small, Ben G.;
Hatley, Oliver;
Jamei, Masoud;
Gardner, Iain;
Johnson, Trevor N.

Publication type:

Article

Prediction of basic drug exposure in milk using a lactation model algorithm integrated within a physiologically based pharmacokinetic model.

Published in:

Biopharmaceutics & Drug Disposition, 2022, v. 43, n. 5, p. 201, doi. 10.1002/bdd.2334

By:

Pansari, Amita;
Faisal, Muhammad;
Jamei, Masoud;
Abduljalil, Khaled

Publication type:

Article

Prediction of liver volume - a population-based approach to meta-analysis of paediatric, adult and geriatric populations - an update.

Published in:

Biopharmaceutics & Drug Disposition, 2017, v. 38, n. 4, p. 290, doi. 10.1002/bdd.2063

By:

Small, Ben G.;
Wendt, Bernd;
Jamei, Masoud;
Johnson, Trevor N.

Publication type:

Article

Does age affect gastric emptying time? A model-based meta-analysis of data from premature neonates through to adults.

Published in:

Biopharmaceutics & Drug Disposition, 2015, v. 36, n. 4, p. 245, doi. 10.1002/bdd.1937

By:

Bonner, Jennifer J.;
Vajjah, Pavan;
Abduljalil, Khaled;
Jamei, Masoud;
Rostami‐Hodjegan, Amin;
Tucker, Geoffrey T.;
Johnson, Trevor N.

Publication type:

Article

Postpartum changes in maternal physiology and milk composition: a comprehensive database for developing lactation physiologically-based pharmacokinetic models.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1517069

By:

Deferm, Neel;
Dinh, Jean;
Pansari, Amita;
Jamei, Masoud;
Abduljalil, Khaled

Publication type:

Article

Application of a systems approach to the bottom-up assessment of pharmacokinetics in obese patients: expected variations in clearance.

Published in:

2011

By:

Ghobadi C;
Johnson TN;
Aarabi M;
Almond LM;
Allabi AC;
Rowland-Yeo K;
Jamei M;
Rostami-Hodjegan A;
Ghobadi, Cyrus;
Johnson, Trevor N;
Aarabi, Mohsen;
Almond, Lisa M;
Allabi, Aurel Constant;
Rowland-Yeo, Karen;
Jamei, Masoud;
Rostami-Hodjegan, Amin

Publication type:

journal article

Application of a Systems Approach to the Bottom-Up Assessment of Pharmacokinetics in Obese Patients.

Published in:

Clinical Pharmacokinetics, 2011, v. 50, n. 12, p. 809, doi. 10.2165/11594420-000000000-00000

By:

Ghobadi, Cyrus;
Johnson, Trevor N.;
Aarabi, Mohsen;
Almond, Lisa M.;
Allabi, Aurel Constant;
Rowland-Yeo, Karen;
Jamei, Masoud;
Rostami-Hodjegan, Amin

Publication type:

Article

An Application of a Physiologically Based Pharmacokinetic Approach to Predict Ceftazidime Pharmacokinetics in a Pregnant Population.

Published in:

Pharmaceutics, 2024, v. 16, n. 4, p. 474, doi. 10.3390/pharmaceutics16040474

By:

Abduljalil, Khaled;
Gardner, Iain;
Jamei, Masoud

Publication type:

Article

Mechanistic PBPK Modelling to Predict the Advantage of the Salt Form of a Drug When Dosed with Acid Reducing Agents.

Published in:

Pharmaceutics, 2021, v. 13, n. 8, p. 1169, doi. 10.3390/pharmaceutics13081169

By:

Chirumamilla, Siri Kalyan;
Banala, Venkatesh Teja;
Jamei, Masoud;
Turner, David B.

Publication type:

Article

Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling to Predict the Impact of CYP2C9 Genetic Polymorphisms, Co-Medication and Formulation on the Pharmacokinetics and Pharmacodynamics of Flurbiprofen.

Published in:

Pharmaceutics, 2020, v. 12, n. 11, p. 1049, doi. 10.3390/pharmaceutics12111049

By:

Loisios-Konstantinidis, Ioannis;
Cristofoletti, Rodrigo;
Jamei, Masoud;
Turner, David;
Dressman, Jennifer

Publication type:

Article

Developing Clinically Relevant Dissolution Specifications for Oral Drug Products—Industrial and Regulatory Perspectives.

Published in:

Pharmaceutics, 2020, v. 12, n. 1, p. 19, doi. 10.3390/pharmaceutics12010019

By:

McAllister, Mark;
Flanagan, Talia;
Boon, Karin;
Pepin, Xavier;
Tistaert, Christophe;
Jamei, Masoud;
Abend, Andreas;
Kotzagiorgis, Evangelos;
Mackie, Claire

Publication type:

Article

Considerations and Caveats when Applying Global Sensitivity Analysis Methods to Physiologically Based Pharmacokinetic Models.

Published in:

AAPS Journal, 2020, v. 22, n. 5, p. N.PAG, doi. 10.1208/s12248-020-00480-x

By:

Liu, Dan;
Li, Linzhong;
Rostami-Hodjegan, Amin;
Bois, Frederic Y.;
Jamei, Masoud

Publication type:

Article

Development and Application of a Physiologically-Based Pharmacokinetic Model to Predict the Pharmacokinetics of Therapeutic Proteins from Full-term Neonates to Adolescents.

Published in:

AAPS Journal, 2020, v. 22, n. 4, p. 1, doi. 10.1208/s12248-020-00460-1

By:

Pan, Xian;
Stader, Felix;
Abduljalil, Khaled;
Gill, Katherine L.;
Johnson, Trevor N.;
Gardner, Iain;
Jamei, Masoud

Publication type:

Article

What Does it Take to Make Model-Informed Precision Dosing Common Practice? Report from the 1st Asian Symposium on Precision Dosing.

Published in:

AAPS Journal, 2019, v. 21, n. 2, p. 1, doi. 10.1208/s12248-018-0286-6

By:

Polasek, Thomas M.;
Rostami-Hodjegan, Amin;
Yim, Dong-Seok;
Jamei, Masoud;
Lee, Howard;
Kimko, Holly;
Kim, Jae Kyoung;
Nguyen, Phuong Thi Thu;
Darwich, Adam S.;
Shin, Jae-Gook

Publication type:

Article

Real Patient and its Virtual Twin: Application of Quantitative Systems Toxicology Modelling in the Cardiac Safety Assessment of Citalopram.

Published in:

AAPS Journal, 2018, v. 20, n. 1, p. 1, doi. 10.1208/s12248-017-0155-8

By:

Patel, Nikunjkumar;
Wiśniowska, Barbara;
Jamei, Masoud;
Polak, Sebastian

Publication type:

Article

Incorporation of the Time-Varying Postprandial Increase in Splanchnic Blood Flow into a PBPK Model to Predict the Effect of Food on the Pharmacokinetics of Orally Administered High-Extraction Drugs.

Published in:

AAPS Journal, 2017, v. 19, n. 4, p. 1205, doi. 10.1208/s12248-017-0099-z

By:

Rose, Rachel;
Turner, David;
Neuhoff, Sibylle;
Jamei, Masoud

Publication type:

Article

Examining the Use of a Mechanistic Model to Generate an In Vivo/ In Vitro Correlation: Journey Through a Thought Process.

Published in:

AAPS Journal, 2016, v. 18, n. 5, p. 1144, doi. 10.1208/s12248-016-9930-1

By:

Mistry, Bipin;
Patel, Nikunjkumar;
Jamei, Masoud;
Rostami-Hodjegan, Amin;
Martinez, Marilyn

Publication type:

Article

A Bottom-Up Whole-Body Physiologically Based Pharmacokinetic Model to Mechanistically Predict Tissue Distribution and the Rate of Subcutaneous Absorption of Therapeutic Proteins.

Published in:

AAPS Journal, 2016, v. 18, n. 1, p. 156, doi. 10.1208/s12248-015-9819-4

By:

Gill, Katherine;
Gardner, Iain;
Li, Linzhong;
Jamei, Masoud

Publication type:

Article

Are Physiologically Based Pharmacokinetic Models Reporting the Right C? Central Venous Versus Peripheral Sampling Site.

Published in:

AAPS Journal, 2015, v. 17, n. 5, p. 1268, doi. 10.1208/s12248-015-9796-7

By:

Musther, Helen;
Gill, Katherine;
Chetty, Manoranjenni;
Rostami-Hodjegan, Amin;
Rowland, Malcolm;
Jamei, Masoud

Publication type:

Article

Simulation of Monoclonal Antibody Pharmacokinetics in HumansUsing a Minimal Physiologically Based Model.

Published in:

AAPS Journal, 2014, v. 16, n. 5, p. 1097, doi. 10.1208/s12248-014-9640-5

By:

Li, Linzhong;
Gardner, Iain;
Dostalek, Miroslav;
Jamei, Masoud

Publication type:

Article

Changes in Individual Drug-Independent System Parameters during Virtual Paediatric Pharmacokinetic Trials: Introducing Time-Varying Physiology into a Paediatric PBPK Model.

Published in:

AAPS Journal, 2014, v. 16, n. 3, p. 568, doi. 10.1208/s12248-014-9592-9

By:

Abduljalil, Khaled;
Jamei, Masoud;
Rostami-Hodjegan, Amin;
Johnson, Trevor N.

Publication type:

Article

Population-Based Mechanistic Prediction of Oral Drug Absorption.

Published in:

AAPS Journal, 2009, v. 11, n. 2, p. 225, doi. 10.1208/s12248-009-9099-y

By:

Jamei, Masoud;
Turner, David;
Yang, Jiansong;
Neuhoff, Sibylle;
Polak, Sebastian;
Rostami-Hodjegan, Amin;
Tucker, Geoffrey

Publication type:

Article