Works by Jakubik, Jan

Results: 57

Subtype-selective inhibition of [methyl-3H]-N-methylscopolamine binding to muscarinic receptors by alpha-truxillic acid esters.

Published in:

1999

By:

Lysíková, Michaela;
Fuksová, Květa;
Elbert, Tomáš;
Jakubík, Jan;
Tuček, Stanislav;
Lysíková, M;
Fuksová, K;
Elbert, T;
Jakubík, J;
Tucek, S

Publication type:

journal article

Agonist-selective activation of individual G-proteins by muscarinic receptors.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-60259-4

By:

Nelic, Dominik;
Chetverikov, Nikolai;
Hochmalová, Martina;
Diaz, Christina;
Doležal, Vladimír;
Boulos, John;
Jakubík, Jan;
Martemyanov, Kirill;
Janoušková-Randáková, Alena

Publication type:

Article

Towards predictive docking at aminergic G-protein coupled receptors.

Published in:

Journal of Molecular Modeling, 2015, v. 21, n. 11, p. 1, doi. 10.1007/s00894-015-2824-9

By:

Jakubík, Jan;
El-Fakahany, Esam E.;
Doležal, Vladimír

Publication type:

Article

Muscarinic Receptors in Cardioprotection and Vascular Tone Regulation.

Published in:

Physiological Research, 2024, v. 73, p. S389, doi. 10.33549/physiolres.935270

By:

DOLEJŠÍ, Eva;
JANOUŠKOVÁ, Alena;
JAKUBÍK, Jan

Publication type:

Article

Weak toxin WTX from Naja kaouthia cobra venom interacts with both nicotinic and muscarinic acetylcholine receptors.

Published in:

FEBS Journal, 2009, v. 276, n. 18, p. 5065, doi. 10.1111/j.1742-4658.2009.07203.x

By:

Mordvintsev, Dmitry Yu.;
Polyak, Yakov L.;
Rodionov, Dmitry I.;
Jakubik, Jan;
Dolezal, Vladimir;
Karlsson, Evert;
Tsetlin, Victor I.;
Utkin, Yuri N.

Publication type:

Article

Modulation of Muscarinic Signalling in the Central Nervous System by Steroid Hormones and Neurosteroids.

Published in:

2023

By:

Szczurowska, Ewa;
Szánti-Pintér, Eszter;
Chetverikov, Nikolai;
Randáková, Alena;
Kudová, Eva;
Jakubík, Jan

Publication type:

Literature Review

Allosteric Modulation of Muscarinic Receptors by Cholesterol, Neurosteroids and Neuroactive Steroids.

Published in:

2022

By:

Szczurowska, Ewa;
Szánti-Pintér, Eszter;
Randáková, Alena;
Jakubík, Jan;
Kudova, Eva

Publication type:

Literature Review

Fusion with Promiscuous Gα 16 Subunit Reveals Signaling Bias at Muscarinic Receptors.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 18, p. 10089, doi. 10.3390/ijms221810089

By:

Randáková, Alena;
Nelic, Dominik;
Hochmalová, Martina;
Zimčík, Pavel;
Mulenga, Mutale Jane;
Boulos, John;
Jakubík, Jan

Publication type:

Article

Allosteric Modulation of GPCRs of Class A by Cholesterol.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 4, p. 1953, doi. 10.3390/ijms22041953

By:

Jakubík, Jan;
El-Fakahany, Esam E.;
Shpakov, Alexander O.

Publication type:

Article

Similarity-Based Summarization of Music Files for Support Vector Machines.

Published in:

Complexity, 2018, p. 1, doi. 10.1155/2018/1935938

By:

Jakubik, Jan;
Kwaśnicka, Halina

Publication type:

Article

On homology modeling of the M muscarinic acetylcholine receptor subtype.

Published in:

Journal of Computer-Aided Molecular Design, 2013, v. 27, n. 6, p. 525, doi. 10.1007/s10822-013-9660-8

By:

Jakubík, Jan;
Randáková, Alena;
Doležal, Vladimír

Publication type:

Article

Novel M<sub>2</sub> -selective, G<sub>i</sub> -biased agonists of muscarinic acetylcholine receptors.

Published in:

2020

By:

Randáková, Alena;
Nelic, Dominik;
Ungerová, Dana;
Nwokoye, Peter;
Su, Qiwen;
Doležal, Vladimír;
El‐Fakahany, Esam E.;
Boulos, John;
Jakubík, Jan;
El-Fakahany, Esam E

Publication type:

journal article

Novel long-acting antagonists of muscarinic ACh receptors.

Published in:

2018

By:

Randáková, Alena;
Rudajev, Vladimír;
Doležal, Vladimír;
Boulos, John;
Jakubík, Jan

Publication type:

journal article

Kompakt erzeugte Verbandsgruppen.

Published in:

Mathematische Nachrichten, 1965, v. 30, n. 3/4, p. 193, doi. 10.1002/mana.19650300306

By:

Jakubík, Ján

Publication type:

Article

Implementing the Kids' Athletics Program in the System of Increasing the Level of Physical Performance of Youth.

Published in:

Physical Education Theory & Methodology, 2025, v. 25, n. 1, p. 166, doi. 10.17309/tmfv.2025.1.20

By:

Jakubík, Ján;
Bro'áni, Jaroslav

Publication type:

Article

Convex subalgebras of upper bounded GMV-algebras.

Published in:

Mathematica Slovaca, 2016, v. 66, n. 2, p. 379, doi. 10.1515/ms-2015-0143

By:

Jakubík, Ján

Publication type:

Article

LEXICO GROUPS AND DIRECT PRODUCTS OF LATTICE ORDERED GROUPS.

Published in:

Mathematica Slovaca, 2016, v. 66, n. 1, p. 35, doi. 10.1515/ms-2015-0113

By:

JAKUBÍK, JÁN

Publication type:

Article

Torsion Radicals and Torsion Classes of Cyclically Ordered Groups.

Published in:

Mathematica Slovaca, 2015, v. 65, n. 2, p. 313, doi. 10.1515/ms-2015-0025

By:

Jákubík, Jan;
Lihoyá, Judita

Publication type:

Article

Further Properties of the Lattice of Torsion Classes of Abelian Cyclically Ordered Groups.

Published in:

Mathematica Slovaca, 2015, v. 65, n. 1, p. 13, doi. 10.1515/ms-2015-0002

By:

Lihová, Judita;
Jakubík, Ján

Publication type:

Article

On a type of distributivity of lattice ordered groups.

Published in:

Mathematica Slovaca, 2014, v. 64, n. 2, p. 281, doi. 10.2478/s12175-014-0202-1

By:

Jakubík, Ján

Publication type:

Article

Weak relatively uniform convergences on MV-algebras.

Published in:

Mathematica Slovaca, 2013, v. 63, n. 1, p. 13, doi. 10.2478/s12175-012-0078-x

By:

Černák, Štefan;
Jakubík, Ján

Publication type:

Article

Cantor extension of an abelian lattice ordered group equipped with a weak relatively uniform convergence.

Published in:

Mathematica Slovaca, 2012, v. 62, n. 5, p. 841, doi. 10.2478/s12175-012-0049-2

By:

Jakubík, Ján;
Černák, Štefan

Publication type:

Article

Generalized Specker lattice-ordered groups and two types of distributivity.

Published in:

Mathematica Slovaca, 2013, v. 63, n. 1, p. 5, doi. 10.2478/s12175-012-0077-y

By:

Jakubík, Ján;
Lihová, Judita

Publication type:

Article

Torsion classes of abelian cyclically ordered groups.

Published in:

Mathematica Slovaca, 2012, v. 62, n. 4, p. 633, doi. 10.2478/s12175-012-0036-7

By:

Jakubík, Ján

Publication type:

Article

On α-complete retracts of specker lattice ordered groups.

Published in:

Mathematica Slovaca, 2012, v. 62, n. 3, p. 425, doi. 10.2478/s12175-012-0019-8

By:

Jakubík, Ján

Publication type:

Article

Torsion classes of generalized Boolean algebras.

Published in:

Mathematica Slovaca, 2012, v. 62, n. 3, p. 399, doi. 10.2478/s12175-012-0017-x

By:

Jakubík, Ján

Publication type:

Article

Banaschewski's theorem for GMV-algebras.

Published in:

Mathematica Slovaca, 2012, v. 62, n. 2, p. 157, doi. 10.2478/s12175-012-0001-5

By:

Jakubík, Ján

Publication type:

Article

Weak relatively uniform convergences on abelian lattice ordered groups.

Published in:

Mathematica Slovaca, 2011, v. 61, n. 5, p. 687, doi. 10.2478/s12175-011-0039-9

By:

Černák, Štefan;
Jakubík, Ján

Publication type:

Article

Higher degrees of distributivity in complete generalized MV-algebras.

Published in:

Mathematica Slovaca, 2011, v. 61, n. 3, p. 341, doi. 10.2478/s12175-011-0016-3

By:

Jakubík, Ján

Publication type:

Article

Isometries and direct product decompositions of GMV-algebras.

Published in:

Mathematica Slovaca, 2010, v. 60, n. 5, p. 591, doi. 10.2478/s12175-010-0034-6

By:

Jakubík, Ján

Publication type:

Article

Relatively uniform convergences in archimedean lattice ordered groups.

Published in:

Mathematica Slovaca, 2010, v. 60, n. 4, p. 447, doi. 10.2478/s12175-010-0024-8

By:

Jakubík, Ján;
Černák, Štefan

Publication type:

Article

On lattice embeddings of a lattice into its intervals.

Published in:

Mathematica Slovaca, 2010, v. 60, n. 2, p. 189, doi. 10.2478/s12175-010-0005-y

By:

Jakubík, Ján

Publication type:

Article

On idempotent modifications of generalized MV-algebras.

Published in:

Mathematica Slovaca, 2010, v. 60, n. 2, p. 179, doi. 10.2478/s12175-010-0004-z

By:

Jakubík, Ján

Publication type:

Article

Radical classes and weak radical mappings of GMV-algebras.

Published in:

Mathematica Slovaca, 2008, v. 58, n. 6, p. 719, doi. 10.2478/s12175-008-0104-1

By:

Jakubík, Ján

Publication type:

Article

Sequential convergences on cyclically ordered groups without Urysohn’s axiom.

Published in:

Mathematica Slovaca, 2008, v. 58, n. 6, p. 739, doi. 10.2478/s12175-008-0105-0

By:

Jakubík, Ján

Publication type:

Article

Formations of lattice ordered groups and of GMV-algebras.

Published in:

Mathematica Slovaca, 2008, v. 58, n. 5, p. 521, doi. 10.2478/s12175-008-0091-2

By:

Jakubík, Ján

Publication type:

Article

Sequential convergences on MV-algebras without Urysohn’s axiom.

Published in:

Mathematica Slovaca, 2008, v. 58, n. 3, p. 289, doi. 10.2478/s12175-008-0074-3

By:

Jakubík, Ján

Publication type:

Article

K-Radical classes and product radical classes of MV-algebras.

Published in:

Mathematica Slovaca, 2008, v. 58, n. 2, p. 143, doi. 10.2478/s12175-008-0062-7

By:

Jakubík, Ján

Publication type:

Article

On a cancellation rule for subdirect products of lattice ordered groups and of GMV-algebras.

Published in:

Mathematica Slovaca, 2007, v. 57, n. 3, p. 201, doi. 10.2478/s12175-007-0016-5

By:

Jakubík, Ján

Publication type:

Article

Current Advances in Allosteric Modulation of Muscarinic Receptors.

Published in:

Biomolecules (2218-273X), 2020, v. 10, n. 2, p. 325, doi. 10.3390/biom10020325

By:

Jakubik, Jan;
El-Fakahany, Esam E.

Publication type:

Article

Progress on the development of Class A GPCR‐biased ligands.

Published in:

British Journal of Pharmacology, 2025, v. 182, n. 14, p. 3249, doi. 10.1111/bph.17301

By:

Morales, Paula;
Scharf, Magdalena M.;
Bermudez, Marcel;
Egyed, Attila;
Franco, Rafael;
Hansen, Olivia K.;
Jagerovic, Nadine;
Jakubík, Jan;
Keserű, György M.;
Kiss, Dóra Judit;
Kozielewicz, Pawel;
Larsen, Olav;
Majellaro, Maria;
Mallo‐Abreu, Ana;
Navarro, Gemma;
Prieto‐Díaz, Rubén;
Rosenkilde, Mette M.;
Sotelo, Eddy;
Stark, Holger;
Werner, Tobias

Publication type:

Article

Analysis of equilibrium binding of an orthosteric tracer and two allosteric modulators.

Published in:

PLoS ONE, 2019, v. 14, n. 3, p. 1, doi. 10.1371/journal.pone.0214255

By:

Jakubík, Jan;
Randáková, Alena;
El-Fakahany, Esam E.;
Doležal, Vladimír

Publication type:

Article

Protection by Alcuronium of Muscarinic Receptors Against Chemical Inactivation and Location of the Allosteric Binding Site for Alcuronium.

Published in:

Journal of Neurochemistry, 1994, v. 63, n. 5, p. 1932, doi. 10.1046/j.1471-4159.1994.63051932.x

By:

Jakubík, Jan;
Tuček, Stanislav

Publication type:

Article

Synthesis of N-Substituted Piperidine Salts as Potential Muscarinic Ligands for Alzheimer's Applications.

Published in:

Journal of Heterocyclic Chemistry, 2013, v. 50, n. 6, p. 1363, doi. 10.1002/jhet.1742

By:

Boulos, John;
Jakubik, Jan;
Randakova, Alena;
Avila, Cristina

Publication type:

Article

A critical re-evaluation of the slope factor of the operational model of agonism: When to exponentiate operational efficacy.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-45004-7

By:

Randáková, Alena;
Nelic, Dominik;
Jakubík, Jan

Publication type:

Article

The relationship between the kinematic parameters of the block start and the first step speed in female representatives of the Slovak Republic in athletic sprints.

Published in:

Journal of Physical Education & Sport, 2023, v. 23, n. 4, p. 1016, doi. 10.7752/jpes.2023.04127

By:

BROĎÁNI, JAROSLAV;
KOVAČOVICOVÁ, LENKA;
JAKUBÍK, JÁN

Publication type:

Article

Influence of kids' athletics and athletic movement games on the development of general physical performance of pupils in the primary education.

Published in:

Journal of Physical Education & Sport, 2023, v. 23, n. 1, p. 219, doi. 10.7752/jpes.2023.01027

By:

JAKUBÍK, JÁN;
BROĎÁNI, JAROSLAV

Publication type:

Article

Insights into the operational model of agonism of receptor dimers.

Published in:

Expert Opinion on Drug Discovery, 2022, v. 17, n. 11, p. 1181, doi. 10.1080/17460441.2023.2147502

By:

Jakubík, Jan;
Randáková, Alena

Publication type:

Article

Determinants of positive cooperativity between strychnine-like allosteric modulators and N-methylscopolamine at muscarinic receptors.

Published in:

Journal of Molecular Neuroscience, 2006, v. 30, n. 1/2, p. 111, doi. 10.1385/JMN:30:1:111

By:

Jakubík, Jan;
Doležal, Vladimír

Publication type:

Article

The operational model of allosteric modulation of pharmacological agonism.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-71228-y

By:

Jakubík, Jan;
Randáková, Alena;
Chetverikov, Nikolai;
El-Fakahany, Esam E.;
Doležal, Vladimír

Publication type:

Article