Works by Jairath, Vipul

Results: 189

Differentiating IL-23 Inhibitors in Crohn's Disease.

Published in:

Drugs, 2025, v. 85, n. 6, p. 725, doi. 10.1007/s40265-025-02183-z

By:

Nardone, Olga Maria;
Vuyyuru, Sudheer K.;
Yuan, Yuhong;
Hanzel, Jurij;
Jairath, Vipul

Publication type:

Article

Risankizumab Is Associated With Normalization of Biomarkers in Patients With Crohn's Disease: Results From the Phase 3 ADVANCE, MOTIVATE, and FORTIFY Studies Open Access.

Published in:

Journal of Crohn's & Colitis, 2025, v. 19, n. 4, p. 1, doi. 10.1093/ecco-jcc/jjae164

By:

Atreya, Raja;
Ferrante, Marc;
Panaccione, Remo;
Feagan, Brian;
Shchukina, Oksana;
Jairath, Vipul;
Rieder, Florian;
Hisamatsu, Tadakazu;
Siegmund, Britta;
Kligys, Kristina;
Song, Alexandra;
Zambrano, Javier;
Mallick, Madhuja;
Zhang, Yafei;
Armuzzi, Alessandro;
D'Haens, Geert

Publication type:

Article

Novel outcomes in inflammatory bowel disease Open Access.

Published in:

Journal of Crohn's & Colitis, 2025, v. 19, n. 4, p. 1, doi. 10.1093/ecco-jcc/jjaf040

By:

Jairath, Vipul;
Narula, Neeraj;
Ungaro, Ryan C;
Bautista, Itzel Romo;
Adsul, Shashi

Publication type:

Article

Use of Modified Multiplier of the Simple Endoscopic Score for Crohn's Disease Endoscopic Improvement Thresholds Enhances Effect Size Differentiation Between Adalimumab Versus Placebo: A Post Hoc Analysis of the EXTEND Trial Open Access.

Published in:

Journal of Crohn's & Colitis, 2025, v. 19, n. 4, p. 1, doi. 10.1093/ecco-jcc/jjae171

By:

Wong, Emily C L;
Dulai, Parambir S;
Marshall, John K;
Laroux, Stephen;
Jairath, Vipul;
Reinisch, Walter;
Narula, Neeraj

Publication type:

Article

Upadacitinib Monotherapy After Tofacitinib Failure Was Successful for Induction But Not Maintenance of Remission in Medically Refractory Ulcerative Colitis.

Published in:

ACG Case Reports Journal, 2025, v. 12, n. 4, p. 1, doi. 10.14309/crj.0000000000001673

By:

Chatto, Mark;
Jairath, Vipul

Publication type:

Article

A Comparison of Treatment Effect Sizes in Matched Phase 2 and Phase 3 Trials of Advanced Therapeutics in Inflammatory Bowel Disease: Systematic Review and Meta-Analysis.

Published in:

Clinical & Translational Gastroenterology, 2023, v. 14, n. 11, p. e00629, doi. 10.14309/ctg.0000000000000629

By:

Hanzel, Jurij;
Solitano, Virginia;
Zou, Lily;
Zou, G.Y.;
Peyrin-Biroulet, Laurent;
Danese, Silvio;
Singh, Siddharth;
Ma, Christopher;
Wils, Pauline;
Jairath, Vipul

Publication type:

Article

Simplified Machine Learning Models Can Accurately Identify High-Need High-Cost Patients With Inflammatory Bowel Disease.

Published in:

Clinical & Translational Gastroenterology, 2022, v. 13, n. 7, p. e00507, doi. 10.14309/ctg.0000000000000507

By:

Nguyen, Nghia H.;
Patel, Sagar;
Gabunilas, Jason;
Qian, Alexander S.;
Cecil, Alan;
Jairath, Vipul;
Sandborn, William J.;
Ohno-Machado, Lucila;
Chen, Peter L.;
Singh, Siddharth

Publication type:

Article

Systematic Review: Patient Perceptions of Monitoring Tools in Inflammatory Bowel Disease.

Published in:

Journal of the Canadian Association of Gastroenterology, 2021, v. 4, n. 2, p. e31, doi. 10.1093/jcag/gwaa001

By:

Goodsall, Thomas M;
Noy, Richard;
Nguyen, Tran M;
Costello, Samuel P;
Jairath, Vipul;
Bryant, Robert V

Publication type:

Article

Development of a Global Rating Scale for Inflammatory Bowel Disease.

Published in:

Journal of the Canadian Association of Gastroenterology, 2020, v. 3, n. 1, p. 4, doi. 10.1093/jcag/gwz017

By:

Bitton, Alain;
Devitt, Katharine S;
Bressler, Brian;
Heatherington, Joan;
Jairath, Vipul;
Jones, Jennifer;
Moayyedi, Paul;
Weizman, Adam V;
Dubé, Catherine;
MacIntosh, Donald;
Nguyen, Geoffrey C;
Network, The Promoting Access and Care through Centres of Excellence (PACE)

Publication type:

Article

A randomized trial evaluating the utility of non-targeted biopsies for colorectal neoplasia detection in adults with inflammatory bowel disease: a pilot study protocol.

Published in:

Pilot & Feasibility Studies, 2024, v. 10, n. 1, p. 1, doi. 10.1186/s40814-023-01434-8

By:

Murthy, Sanjay K.;
Marderfeld, Luba;
Fergusson, Dean;
Ramsay, Tim;
Bernstein, Charles N.;
Nguyen, Geoffrey C.;
Jairath, Vipul;
Riddell, Robert

Publication type:

Article

Psychometric evaluation of the Functional Assessment of chronic illness therapy–fatigue (FACIT-Fatigue) in adults with moderately to severely active Crohn's disease.

Published in:

Quality of Life Research, 2025, v. 34, n. 2, p. 509, doi. 10.1007/s11136-024-03829-3

By:

Regueiro, Miguel;
Su, Sylvia;
Vadhariya, Aisha;
Zhou, Xian;
Durand, Frederick;
Stassek, Larissa;
Kawata, Ariane K.;
Clucas, Claudine;
Jairath, Vipul

Publication type:

Article

CASE STUDY SERIES IN IBD. Case Report: Medical Management of Acute Severe Ulcerative Colitis.

Published in:

Gastroenterology & Hepatology, 2023, v. 19, n. 10, p. 621

By:

Vuyyuru, Sudheer Kumar;
Jairath, Vipul;
Hanžel, Jurij;
Ma, Christopher;
Feagan, Brian G.

Publication type:

Article

Advanced Combination Treatment With Biologic Agents and Novel Small Molecule Drugs for Inflammatory Bowel Disease.

Published in:

Gastroenterology & Hepatology, 2023, v. 19, n. 5, p. 251

By:

Solitano, Virginia;
Ma, Christopher;
Hanžel, Jurij;
Panaccione, Remo;
Feagan, Brian G.;
Jairath, Vipul

Publication type:

Article

Case Report: Managing Postoperative Crohn's Disease.

Published in:

Gastroenterology & Hepatology, 2022, v. 18, n. 10, p. 568

By:

Hanzel, Jurij;
Vuyyuru, Sudheer Kumar;
Narula, Neeraj;
Ma, Christopher;
Feagan, Brian G.;
Jairath, Vipul

Publication type:

Article

Janus Kinase Inhibitors for the Management of Patients With Inflammatory Bowel Disease.

Published in:

Gastroenterology & Hepatology, 2022, v. 18, n. 1, p. 14

By:

Sedano, Rocio;
Ma, Christopher;
Jairath, Vipul;
Feagan, Brian G.

Publication type:

Article

Access to unpublished protocols and statistical analysis plans of randomised trials.

Published in:

2022

By:

Campbell, David;
McDonald, Cassandra;
Cro, Suzie;
Jairath, Vipul;
Kahan, Brennan C.

Publication type:

journal article

Efficacy and Safety of IL-12/23 and IL-23 Inhibitors for Crohn's Disease: Systematic Review and Meta-Analysis.

Published in:

Digestive Diseases & Sciences, 2023, v. 68, n. 9, p. 3702, doi. 10.1007/s10620-023-08014-z

By:

Vuyyuru, Sudheer Kumar;
Solitano, Virginia;
Hogan, Malcolm;
MacDonald, John K.;
Zayadi, Alexa;
Parker, Claire E.;
Sands, Bruce E.;
Panaccione, Remo;
Narula, Neeraj;
Feagan, Brian G.;
Singh, Siddharth;
Jairath, Vipul;
Ma, Christopher

Publication type:

Article

Comparative Efficacy of Infliximab Versus Tofacitinib for Inducing Remission in Biologic Naive Ulcerative Colitis: A Propensity Matched Study.

Published in:

Digestive Diseases & Sciences, 2023, v. 68, n. 6, p. 2635, doi. 10.1007/s10620-023-07956-8

By:

Wong, Emily C. L.;
Merat, Shahin;
Monaco, Cristina;
Dulai, Parambir S.;
Jairath, Vipul;
Marshall, John K.;
Reinisch, Walter;
Narula, Neeraj

Publication type:

Article

Vedolizumab and Adalimumab in Biologic-Naïve Ulcerative Colitis: Comparison of Patient-Level Clinical Trial Data and VARSITY for Week 6 Clinical Remission.

Published in:

Digestive Diseases & Sciences, 2023, v. 68, n. 6, p. 2658, doi. 10.1007/s10620-023-07825-4

By:

Narula, Neeraj;
Wong, Emily C. L.;
Dulai, Parambir S.;
Marshall, John K.;
Jairath, Vipul;
Reinisch, Walter

Publication type:

Article

International Consensus on Definition of Mild-to-Moderate Ulcerative Colitis Disease Activity in Adult Patients.

Published in:

Medicina (1010660X), 2023, v. 59, n. 1, p. 183, doi. 10.3390/medicina59010183

By:

Caron, Bénédicte;
Jairath, Vipul;
D'Amico, Ferdinando;
Al Awadhi, Sameer;
Dignass, Axel;
Hart, Ailsa L.;
Kobayashi, Taku;
Kotze, Paulo Gustavo;
Magro, Fernando;
Siegmund, Britta;
Paridaens, Kristine;
Danese, Silvio;
Peyrin-Biroulet, Laurent

Publication type:

Article

Acute severe ulcerative colitis: latest evidence and therapeutic implications.

Published in:

Therapeutic Advances in Chronic Disease, 2018, v. 9, n. 2, p. 65, doi. 10.1177/2040622317742095

By:

Dulai, Parambir S.;
Jairath, Vipul

Publication type:

Article

Practical management of mild-to-moderate ulcerative colitis: an international expert consensus.

Published in:

Expert Review of Gastroenterology & Hepatology, 2024, v. 18, n. 8, p. 421, doi. 10.1080/17474124.2024.2397650

By:

D'Amico, Ferdinando;
Magro, Fernando;
Dignass, Axel;
Al Awadhi, Sameer;
Gutierrez Casbas, Ana;
Queiroz, Natália Sousa Freitas;
Rydzewska, Grażyna;
Duk Ye, Byong;
Ran, Zhihua;
Hart, Ailsa;
Jairath, Vipul;
Fiorino, Gionata;
Peyrin-Biroulet, Laurent;
Danese, Silvio

Publication type:

Article

Histologic assessments in ulcerative colitis: the evidence behind a new endpoint in clinical trials.

Published in:

Expert Review of Gastroenterology & Hepatology, 2024, v. 18, n. 1-3, p. 73, doi. 10.1080/17474124.2024.2326838

By:

Pai, Rish K.;
D'Haens, Geert;
Kobayashi, Taku;
Sands, Bruce E.;
Travis, Simon;
Jairath, Vipul;
De Hertogh, Gert;
Park, Bomina;
McGinnis, Kim;
Redondo, Isabel;
Lipitz, Nicole G.;
Gibble, Theresa Hunter;
Magro, Fernando

Publication type:

Article

Integrating efficacy and safety of vedolizumab compared with other advanced therapies to assess net clinical benefit of ulcerative colitis treatments: a network meta-analysis.

Published in:

Expert Review of Gastroenterology & Hepatology, 2021, v. 15, n. 6, p. 711, doi. 10.1080/17474124.2021.1880319

By:

Jairath, Vipul;
Chan, Keith;
Lasch, Karen;
Keeping, Sam;
Agboton, Christian;
Blake, Aimee;
Patel, Haridarshan

Publication type:

Article

Update on C-reactive protein and fecal calprotectin: are they accurate measures of disease activity in Crohn's disease?

Published in:

Expert Review of Gastroenterology & Hepatology, 2019, v. 13, n. 4, p. 319, doi. 10.1080/17474124.2019.1563481

By:

Ma, Christopher;
Battat, Robert;
Parker, Claire E.;
Khanna, Reena;
Jairath, Vipul;
Feagan, Brian Gordon

Publication type:

Article

Choosing appropriate analysis methods for cluster randomised cross-over trials with a binary outcome.

Published in:

2017

By:

Morgan, Katy E.;
Forbes, Andrew B.;
Keogh, Ruth H.;
Jairath, Vipul;
Kahan, Brennan C.

Publication type:

journal article

Management of complications in patients with an ileostomy: an umbrella review of systematic reviews for the EndOTrial Consortium.

Published in:

International Journal of Colorectal Disease, 2024, v. 39, n. 1, p. 1, doi. 10.1007/s00384-024-04714-8

By:

Solitano, Virginia;
Vuyyuru, Sudheer Kumar;
Yuan, Yuhong;
Singh, Siddharth;
Narula, Neeraj;
Ma, Christopher;
Hanzel, Jurij;
Hutton, Megan;
Van Koughnett, Julie Ann;
Rieder, Florian;
Jairath, Vipul

Publication type:

Article

External Validation of the Oakland Score to Assess Safe Hospital Discharge Among Adult Patients With Acute Lower Gastrointestinal Bleeding in the US.

Published in:

JAMA Network Open, 2020, v. 3, n. 7, p. e209630, doi. 10.1001/jamanetworkopen.2020.9630

By:

Oakland, Kathryn;
Kothiwale, Sandeepkumar;
Forehand, Tyler;
Jackson, Edmund;
Bucknall, Cliff;
Sey, Michael S. L.;
Singh, Siddharth;
Jairath, Vipul;
Perlin, Jonathan

Publication type:

Article

Practical guidance for managing patients with moderate-to-severe ulcerative colitis using small molecule therapies.

Published in:

Journal of the Canadian Association of Gastroenterology, 2024, v. 7, n. 4, p. 282, doi. 10.1093/jcag/gwae013

By:

Jairath, Vipul;
Afif, Waqqas;
Bressler, Brian;
Pope, Janet E;
Selchen, Daniel;
Targownik, Laura E;
Panaccione, Remo

Publication type:

Article

Impact of Multidisciplinary Conferences on Treatment Plans for Patients With Inflammatory Bowel Disease in a Tertiary Canadian Centre.

Published in:

Journal of the Canadian Association of Gastroenterology, 2021, v. 4, n. 6, p. 284, doi. 10.1093/jcag/gwab004

By:

Hartford, Luke B;
Allen, Laura J;
Lennox, Heather;
Jairath, Vipul;
Koughnett, Julie Ann M Van

Publication type:

Article

Severe Ulcerative Colitis Complicated by Malakoplakia Resulting in Proctocolectomy.

Published in:

ACG Case Reports Journal, 2024, v. 11, n. 1, p. 1, doi. 10.14309/crj.0000000000001257

By:

Alphonsus, Lotus;
De Silva, Theshani A.;
Driman, David;
Jairath, Vipul

Publication type:

Article

Targeting IL-23 for IBD: Rationale and Progress to Date.

Published in:

Drugs, 2023, v. 83, n. 10, p. 873, doi. 10.1007/s40265-023-01882-9

By:

Vuyyuru, Sudheer K.;
Shackelton, Lisa M.;
Hanzel, Jurij;
Ma, Christopher;
Jairath, Vipul;
Feagan, Brian G.

Publication type:

Article

Correction to: Vedolizumab and Extraintestinal Manifestations in Inflammatory Bowel Disease.

Published in:

2021

By:

Hanzel, Jurij;
Ma, Christopher;
Vande Casteele, Niels;
Khanna, Reena;
Jairath, Vipul;
Feagan, Brian G.

Publication type:

Correction Notice

Vedolizumab and Extraintestinal Manifestations in Inflammatory Bowel Disease.

Published in:

Drugs, 2021, v. 81, n. 2, p. 333, doi. 10.1007/s40265-020-01460-3

By:

Hanzel, Jurij;
Ma, Christopher;
Casteele, Niels Vande;
Khanna, Reena;
Jairath, Vipul;
Feagan, Brian G.

Publication type:

Article

Pharmacotherapies for the Treatment of Eosinophilic Esophagitis: State of the Art Review.

Published in:

Drugs, 2019, v. 79, n. 13, p. 1419, doi. 10.1007/s40265-019-01173-2

By:

de Rooij, Willemijn E.;
Dellon, Evan S.;
Parker, Claire E.;
Feagan, Brian G.;
Jairath, Vipul;
Ma, Christopher;
Bredenoord, Albert J.

Publication type:

Article

Innovations in Oral Therapies for Inflammatory Bowel Disease.

Published in:

Drugs, 2019, v. 79, n. 12, p. 1321, doi. 10.1007/s40265-019-01169-y

By:

Ma, Christopher;
Battat, Robert;
Dulai, Parambir S.;
Parker, Claire E.;
Sandborn, William J.;
Feagan, Brian G.;
Jairath, Vipul

Publication type:

Article

Erratum to: Incidence, Prevention and Management of Anti-Drug Antibodies Against Therapeutic Antibodies in Inflammatory Bowel Disease: A Practical Overview.

Published in:

Drugs, 2017, v. 77, n. 4, p. 379, doi. 10.1007/s40265-017-0719-z

By:

Hindryckx, Pieter;
Novak, Gregor;
Vande Casteele, Niels;
Khanna, Reena;
Laukens, Debby;
Jairath, Vipul;
Feagan, Brian

Publication type:

Article

Incidence, Prevention and Management of Anti-Drug Antibodies Against Therapeutic Antibodies in Inflammatory Bowel Disease: A Practical Overview.

Published in:

Drugs, 2017, v. 77, n. 4, p. 363, doi. 10.1007/s40265-017-0693-5

By:

Hindryckx, Pieter;
Novak, Gregor;
Vande Casteele, Niels;
Khanna, Reena;
Laukens, Debby;
Vipul, Jairath;
Feagan, Brian

Publication type:

Article

TL1A Inhibition in Inflammatory Bowel Disease: A Pipeline Review: TL1A Inhibition in IBD: V. Solitano et al.

Published in:

2025

By:

Solitano, Virginia;
Estevinho, Maria Manuela;
Ungaro, Federica;
Magro, Fernando;
Danese, Silvio;
Jairath, Vipul

Publication type:

Literature Review

A Clinical Prediction Model to Determine Probability of Response to Certolizumab Pegol for Crohn's Disease.

Published in:

BioDrugs, 2022, v. 36, n. 1, p. 85, doi. 10.1007/s40259-021-00512-8

By:

Lefevre, Pavine L. C.;
Dulai, Parambir S.;
Wang, Zhongya;
Guizzetti, Leonardo;
Feagan, Brian G.;
Pop, Anca;
Yassine, Mohamed;
Shackelton, Lisa M.;
Jairath, Vipul;
Sandborn, William J.;
Vande Casteele, Niels

Publication type:

Article

Anti-Drug Antibody Formation Against Biologic Agents in Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis.

Published in:

BioDrugs, 2021, v. 35, n. 6, p. 715, doi. 10.1007/s40259-021-00507-5

By:

Bots, Steven J.;
Parker, Claire E.;
Brandse, Johannan F.;
Löwenberg, Mark;
Feagan, Brian G.;
Sandborn, William J.;
Jairath, Vipul;
D'Haens, Geert;
Vande Casteele, Niels

Publication type:

Article

Clinical Trials of IL-12/IL-23 Inhibitors in Inflammatory Bowel Disease.

Published in:

BioDrugs, 2020, v. 34, n. 6, p. 713, doi. 10.1007/s40259-020-00451-w

By:

Almradi, Ahmed;
Hanzel, Jurij;
Sedano, Rocio;
Parker, Claire E.;
Feagan, Brian G.;
Ma, Christopher;
Jairath, Vipul

Publication type:

Article

The safety of vedolizumab for the treatment of ulcerative colitis.

Published in:

Expert Opinion on Drug Safety, 2017, v. 16, n. 4, p. 501, doi. 10.1080/14740338.2017.1300251

By:

Novak, Gregor;
Hindryckx, Pieter;
Khanna, Reena;
Jairath, Vipul;
Feagan, Brian G.

Publication type:

Article

Pharmacokinetic drug evaluation of budesonide in the treatment of Crohn’s disease.

Published in:

Expert Opinion on Drug Metabolism & Toxicology, 2017, v. 13, n. 7, p. 793, doi. 10.1080/17425255.2017.1340454

By:

Kwapisz, Lukasz;
Jairath, Vipul;
Khanna, Reena;
Feagan, Brian

Publication type:

Article

Response to prothrombin complex concentrate to correct acquired abnormalities of the clotting screen in patients with liver impairment.

Published in:

Liver International, 2017, v. 37, n. 8, p. 1250, doi. 10.1111/liv.13412

By:

Desborough, Michael J. R.;
Stanworth, Simon J.;
Jairath, Vipul

Publication type:

Article

Patterns of blood component use in cirrhosis: a nationwide study.

Published in:

Liver International, 2016, v. 36, n. 4, p. 522, doi. 10.1111/liv.12999

By:

Desborough, Michael J. R.;
Hockley, Brian;
Sekhar, Mallika;
Burroughs, Andrew K.;
Stanworth, Simon J.;
Jairath, Vipul

Publication type:

Article

Association of Bowel Urgency With Quality-of-Life Measures in Patients With Moderately-to-Severely Active Ulcerative Colitis: Results From Phase 3 LUCENT-1 (Induction) and LUCENT-2 (Maintenance) Studies.

Published in:

Crohn's & Colitis 360, 2024, v. 6, n. 1, p. 1, doi. 10.1093/crocol/otae001

By:

Long, Millie D;
Schreiber, Stefan;
Hibi, Toshifumi;
Gibble, Theresa Hunter;
Fisher, Deborah A;
Park, Gina;
Moses, Richard E;
Higgins, Peter D R;
Lindsay, James O;
Lee, Scott D;
Escobar, Rodrigo;
Jairath, Vipul

Publication type:

Article

Mirikizumab Improves Quality of Life in Patients With Moderately-to-Severely Active Ulcerative Colitis: Results From the Phase 3 LUCENT-1 Induction and LUCENT-2 Maintenance Studies.

Published in:

Crohn's & Colitis 360, 2023, v. 5, n. 4, p. 1, doi. 10.1093/crocol/otad070

By:

Sands, Bruce E;
Feagan, Brian G;
Gibble, Theresa Hunter;
Traxler, Kristina A;
Morris, Nathan;
Eastman, William J;
Schreiber, Stefan;
Jairath, Vipul;
Long, Millie D;
Armuzzi, Alessandro

Publication type:

Article

Interventions for Adjunctive Care in Patients With Inflammatory Bowel Disease and Permanent Ileostomy: A Systematic Review.

Published in:

Crohn's & Colitis 360, 2024, v. 6, n. 4, p. 1, doi. 10.1093/crocol/otae056

By:

Vuyyuru, Sudheer Kumar;
Solitano, Virginia;
Yuan, Yuhong;
Narula, Neeraj;
Singh, Siddharth;
Ma, Christopher;
Rieder, Florian;
Jairath, Vipul

Publication type:

Article

Differences Between the 2016 and 2022 Food and Drug Administration Guidance—Implications for Design and Interpretation of Clinical Trials in Ulcerative Colitis.

Published in:

Crohn's & Colitis 360, 2024, v. 6, n. 2, p. 1, doi. 10.1093/crocol/otae038

By:

Hanzel, Jurij;
Ma, Christopher;
Peyrin-Biroulet, Laurent;
Danese, Silvio;
Sands, Bruce E;
Jairath, Vipul

Publication type:

Article