Works by Iyer, Malliga R.

Results: 20

Peripheral Hybrid CB1R and iNOS Antagonist MRI-1867 Displays Anti-Fibrotic Efficacy in Bleomycin-Induced Skin Fibrosis.

Published in:

Frontiers in Endocrinology, 2021, v. 12, p. 1, doi. 10.3389/fendo.2021.744857

By:

Zawatsky, Charles N.;
Park, Joshua K.;
Abdalla, Jasmina;
Kunos, George;
Iyer, Malliga R.;
Cinar, Resat

Publication type:

Article

Synthesis of 13C6‐labeled, dual‐target inhibitor of cannabinoid‐1 receptor (CB1R) and inducible nitric oxide synthase (iNOS).

Published in:

Journal of Labelled Compounds & Radiopharmaceuticals, 2018, v. 61, n. 10, p. 773, doi. 10.1002/jlcr.3639

By:

Iyer, Malliga R.;
Cinar, Resat;
Coffey, Nathan J.;
Kunos, George

Publication type:

Article

Cover Image.

Published in:

Journal of Labelled Compounds & Radiopharmaceuticals, 2018, v. 61, n. 10, p. i, doi. 10.1002/jlcr.3676

By:

Iyer, Malliga R.;
Cinar, Resat;
Coffey, Nathan J.;
Kunos, George

Publication type:

Article

Synthesis of S-2-(( S)-3-(4-chlorophenyl)- N'-((4-chlorophenyl)sulfonyl)-4-phenyl-4,5-dihydro-1 H-pyrazole-1-carboximidamido)-3-(methyl- d3)butanamide-d5, octadeuterated JD5037.

Published in:

Journal of Labelled Compounds & Radiopharmaceuticals, 2017, v. 60, n. 10, p. 460, doi. 10.1002/jlcr.3521

By:

Iyer, Malliga R.;
Cinar, Resat;
Coffey, Nathan J.;
Chorvat, Robert J.;
Kunos, George

Publication type:

Article

CB1R and iNOS are distinct players promoting pulmonary fibrosis in Hermansky–Pudlak syndrome.

Published in:

Clinical & Translational Medicine, 2021, v. 11, n. 7, p. 1, doi. 10.1002/ctm2.471

By:

Cinar, Resat;
Park, Joshua K.;
Zawatsky, Charles N.;
Coffey, Nathan J.;
Bodine, Steven P.;
Abdalla, Jasmina;
Yokoyama, Tadafumi;
Jourdan, Tony;
Jay, Lindsey;
Zuo, Mei Xing G.;
O'Brien, Kevin J.;
Huang, Junfeng;
Mackie, Ken;
Alimardanov, Asaf;
Iyer, Malliga R.;
Gahl, William A.;
Kunos, George;
Gochuico, Bernadette R.;
Malicdan, May Christine V.

Publication type:

Article

Dual inhibition of cannabinoid CB1 receptor and inducible NOS attenuates obesity-induced chronic kidney disease.

Published in:

2020

By:

Udi, Shiran;
Hinden, Liad;
Ahmad, Majdoleen;
Drori, Adi;
Iyer, Malliga R.;
Cinar, Resat;
Herman‐Edelstein, Michal;
Tam, Joseph;
Herman-Edelstein, Michal

Publication type:

journal article

A patent review on aldehyde dehydrogenase inhibitors: an overview of small molecule inhibitors from the last decade.

Published in:

Expert Opinion on Therapeutic Patents, 2023, v. 33, n. 10, p. 651, doi. 10.1080/13543776.2023.2287515

By:

Kundu, Biswajit;
Iyer, Malliga R.

Publication type:

Article

Soluble epoxide hydrolase inhibitors: an overview and patent review from the last decade.

Published in:

Expert Opinion on Therapeutic Patents, 2022, v. 32, n. 6, p. 629, doi. 10.1080/13543776.2022.2054329

By:

Iyer, Malliga R.;
Kundu, Biswajit;
Wood, Casey M.

Publication type:

Article

Therapeutic approaches targeting the neurotensin receptors.

Published in:

Expert Opinion on Therapeutic Patents, 2021, v. 31, n. 5, p. 361, doi. 10.1080/13543776.2021.1866539

By:

Iyer, Malliga R.;
Kunos, George

Publication type:

Article

Antagonism of Sigma-1 Receptors Blocks Compulsive-Like Eating.

Published in:

Neuropsychopharmacology, 2012, v. 37, n. 12, p. 2593, doi. 10.1038/npp.2012.89

By:

Cottone, Pietro;
Wang, Xiaofan;
Park, Jin Won;
Valenza, Marta;
Blasio, Angelo;
Kwak, Jina;
Iyer, Malliga R;
Steardo, Luca;
Rice, Kenner C;
Hayashi, Teruo;
Sabino, Valentina

Publication type:

Article

Activation of σ-Receptors Induces Binge-like Drinking in Sardinian Alcohol-Preferring Rats.

Published in:

Neuropsychopharmacology, 2011, v. 36, n. 6, p. 1207, doi. 10.1038/npp.2011.5

By:

Sabino, Valentina;
Cottone, Pietro;
Blasio, Angelo;
Iyer, Malliga R.;
Steardo, Luca;
Rice, Kenner C.;
Conti, Bruno;
Koob, George F.;
Zorrilla, Eric P.

Publication type:

Article

The σ-Receptor Antagonist BD-1063 Decreases Ethanol Intake and Reinforcement in Animal Models of Excessive Drinking.

Published in:

Neuropsychopharmacology, 2009, v. 34, n. 6, p. 1482, doi. 10.1038/npp.2008.192

By:

Sabino, Valentina;
Cottone, Pietro;
Yu Zhao;
Iyer, Malliga R.;
Steardo Jr., Luca;
Steardo, Luca;
Rice, Kenner C.;
Conti, Bruno;
Koob, George F.;
Zorrilla, Eric P.

Publication type:

Article

Cholesterol as a modulator of cannabinoid receptor CB2 signaling.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-83245-6

By:

Yeliseev, Alexei;
Iyer, Malliga R.;
Joseph, Thomas T.;
Coffey, Nathan J.;
Cinar, Resat;
Zoubak, Lioudmila;
Kunos, George;
Gawrisch, Klaus

Publication type:

Article

Evaluation of the Therapeutic Potential of Sulfonyl Urea Derivatives as Soluble Epoxide Hydrolase (sEH) Inhibitors.

Published in:

Molecules, 2024, v. 29, n. 13, p. 1, doi. 10.3390/molecules29133036

By:

Kundu, Biswajit;
Dvorácskó, Szabolcs;
Basu, Abhishek;
Pommerolle, Lenny;
Kyu Ah Kim;
Wood, Casey M.;
Gibbs, Eve;
Behee, Madeline;
Tarasova, Nadya I.;
Cinar, Resat;
Iyer, Malliga R.

Publication type:

Article

Effects of a Peripherally Restricted Hybrid Inhibitor of CB1 Receptors and iNOS on Alcohol Drinking Behavior and Alcohol-Induced Endotoxemia.

Published in:

Molecules, 2021, v. 26, n. 16, p. 5089, doi. 10.3390/molecules26165089

By:

Santos-Molina, Luis;
Herrerias, Alexa;
Zawatsky, Charles N.;
Gunduz-Cinar, Ozge;
Cinar, Resat;
Iyer, Malliga R.;
Wood, Casey M.;
Lin, Yuhong;
Gao, Bin;
Kunos, George;
Godlewski, Grzegorz

Publication type:

Article

Anandamide Is a Potential Blood Biomarker of Hermansky-Pudlak Syndrome Pulmonary Fibrosis.

Published in:

American Journal of Respiratory & Critical Care Medicine, 2025, v. 211, n. 4, p. 650, doi. 10.1164/rccm.202406-1143RL

By:

Cinar, Resat;
Basu, Abhishek;
Arif, Muhammad;
Park, Joshua K.;
Zawatsky, Charles N.;
Zuo, Ben Long G.;
Zuo, Mei Xing G.;
O'Brien, Kevin J.;
Behan, Molly;
Introne, Wendy;
Iyer, Malliga R.;
Gahl, William A.;
Malicdan, May Christine V.;
Gochuico, Bernadette R.

Publication type:

Article

Dual inhibition of CB1 receptors and iNOS, as a potential novel approach to the pharmacological management of acute and long COVID‐19.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 10, p. 2121, doi. 10.1111/bph.15461

By:

Cinar, Resat;
Iyer, Malliga R.;
Kunos, George

Publication type:

Article

Rational Design, Synthesis, and Evaluation of Fluorescent CB 2 Receptor Ligands for Live-Cell Imaging: A Comprehensive Review.

Published in:

Pharmaceuticals (14248247), 2023, v. 16, n. 9, p. 1235, doi. 10.3390/ph16091235

By:

Bhattacharjee, Pinaki;
Iyer, Malliga R.

Publication type:

Article

Simultaneous Inhibition of Peripheral CB1R and iNOS Mitigates Obesity-Related Dyslipidemia Through Distinct Mechanisms.

Published in:

2020

By:

Roger, Célia;
Buch, Chloé;
Muller, Tania;
Leemput, Julia;
Demizieux, Laurent;
Passilly-Degrace, Patricia;
Cinar, Resat;
Iyer, Malliga R.;
Kunos, George;
Vergès, Bruno;
Degrace, Pascal;
Jourdan, Tony

Publication type:

journal article

Pharmacological Evaluation of Cannabinoid Receptor Modulators Using GRAB eCB2.0 Sensor.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 9, p. 5012, doi. 10.3390/ijms25095012

By:

Shivshankar, Samay;
Nimely, Josephine;
Puhl III, Henry;
Iyer, Malliga R.

Publication type:

Article

Works by Iyer, Malliga R.

Peripheral Hybrid CB<sub>1</sub>R and iNOS Antagonist MRI-1867 Displays Anti-Fibrotic Efficacy in Bleomycin-Induced Skin Fibrosis.

Synthesis of <sup>13</sup>C<sub>6</sub>‐labeled, dual‐target inhibitor of cannabinoid‐1 receptor (CB<sub>1</sub>R) and inducible nitric oxide synthase (iNOS).

Cover Image.

Synthesis of S-2-(( S)-3-(4-chlorophenyl)- N'-((4-chlorophenyl)sulfonyl)-4-phenyl-4,5-dihydro-1 H-pyrazole-1-carboximidamido)-3-(methyl- d<sub>3</sub>)butanamide-d<sub>5</sub>, octadeuterated JD5037.

CB<sub>1</sub>R and iNOS are distinct players promoting pulmonary fibrosis in Hermansky–Pudlak syndrome.

Dual inhibition of cannabinoid CB<sub>1</sub> receptor and inducible NOS attenuates obesity-induced chronic kidney disease.

A patent review on aldehyde dehydrogenase inhibitors: an overview of small molecule inhibitors from the last decade.

Soluble epoxide hydrolase inhibitors: an overview and patent review from the last decade.

Therapeutic approaches targeting the neurotensin receptors.

Antagonism of Sigma-1 Receptors Blocks Compulsive-Like Eating.

Activation of σ-Receptors Induces Binge-like Drinking in Sardinian Alcohol-Preferring Rats.

The σ-Receptor Antagonist BD-1063 Decreases Ethanol Intake and Reinforcement in Animal Models of Excessive Drinking.

Cholesterol as a modulator of cannabinoid receptor CB2 signaling.

Evaluation of the Therapeutic Potential of Sulfonyl Urea Derivatives as Soluble Epoxide Hydrolase (sEH) Inhibitors.

Effects of a Peripherally Restricted Hybrid Inhibitor of CB1 Receptors and iNOS on Alcohol Drinking Behavior and Alcohol-Induced Endotoxemia.

Anandamide Is a Potential Blood Biomarker of Hermansky-Pudlak Syndrome Pulmonary Fibrosis.

Dual inhibition of CB<sub>1</sub> receptors and iNOS, as a potential novel approach to the pharmacological management of acute and long COVID‐19.

Rational Design, Synthesis, and Evaluation of Fluorescent CB 2 Receptor Ligands for Live-Cell Imaging: A Comprehensive Review.

Simultaneous Inhibition of Peripheral CB1R and iNOS Mitigates Obesity-Related Dyslipidemia Through Distinct Mechanisms.

Pharmacological Evaluation of Cannabinoid Receptor Modulators Using GRAB eCB2.0 Sensor.