Works matching AU Iyer, Lakshminarayan M.

Results: 53

Structure of a lamprey variable lymphocyte receptor in complex with a protein antigen.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 7, p. 725, doi. 10.1038/nsmb.1619

By:

Velikovsky, C. Alejandro;
Lu Deng;
Tasumi, Satoshi;
Iyer, Lakshminarayan M.;
Kerzic, Melissa C.;
Aravind, L.;
Pancer, Zeev;
Mariuzza, Roy A.

Publication type:

Article

Bacterial GRAS domain proteins throw new light on gibberellic acid response mechanisms.

Published in:

Bioinformatics, 2012, v. 28, n. 19, p. 2407, doi. 10.1093/bioinformatics/bts464

By:

Zhang, Dapeng;
Iyer, Lakshminarayan M.;
Aravind, L.

Publication type:

Article

BEN: a novel domain in chromatin factors and DNA viral proteins.

Published in:

Bioinformatics, 2008, v. 24, n. 4, p. 458, doi. 10.1093/bioinformatics/btn007

By:

Saraswathi Abhiman;
Lakshminarayan M. Iyer;
L. Aravind

Publication type:

Article

The DOMON domains are involved in heme and sugar recognition.

Published in:

Bioinformatics, 2007, v. 23, n. 20, p. 2660, doi. 10.1093/bioinformatics/btm411

By:

Iyer, Lakshminarayan M.;
Anantharaman, Vivek;
Aravind, L.

Publication type:

Article

Gene Networks and Chromatin and Transcriptional Regulation of the Phaseolin Promoter in Arabidopsis.

Published in:

Plant Cell, 2013, v. 25, n. 7, p. 2601, doi. 10.1105/tpc.113.112714

By:

Sundaram, Sabarinath;
Kertbundit, Sunee;
Shakirov, Eugene V.;
Iyer, Lakshminarayan M.;
Juříček, Miloslav;
Hall, Timothy C.

Publication type:

Article

The catalytic domains of thiamine triphosphatase and CyaB-like adenylyl cyclase define a novel superfamily of domains that bind organic phosphates.

Published in:

BMC Genomics, 2002, v. 3, p. 33, doi. 10.1186/1471-2164-3-33

By:

Iyer, Lakshminarayan M.;
Aravind, L.

Publication type:

Article

Ancient conserved domains shared by animal soluble guanylyl cyclases and bacterial signaling proteins.

Published in:

BMC Genomics, 2003, v. 4, p. 5, doi. 10.1186/1471-2164-4-5

By:

Iyer, Lakshminarayan M.;
Anantharaman, Vivek;
Aravind, L.

Publication type:

Article

Classification and evolutionary history of the single-strand annealing proteins, RecT, Redβ, ERF and RAD52.

Published in:

BMC Genomics, 2002, v. 3, p. 8, doi. 10.1186/1471-2164-3-8

By:

Iyer, Lakshminarayan M.;
Koonin, Eugene V.;
Aravind, L.

Publication type:

Article

Evolution and diversification of lamprey antigen receptors: evidence for involvement of an AID-APOBEC family cytosine deaminase.

Published in:

Nature Immunology, 2007, v. 8, n. 6, p. 647, doi. 10.1038/ni1463

By:

Rogozin, Igor B;
Iyer, Lakshminarayan M;
Liang, Lizhi;
Glazko, Galina V;
Liston, Victoria G;
Pavlov, Youri I;
Aravind, L;
Pancer, Zeev

Publication type:

Article

Bacterial death and TRADD-N domains help define novel apoptosis and immunity mechanisms shared by prokaryotes and metazoans.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.70394

By:

Kaur, Gurmeet;
Iyer, Lakshminarayan M.;
Burroughs, A. Maxwell;
Aravind, L.

Publication type:

Article

Gene flow and biological conflict systems in the origin and evolution of eukaryotes.

Published in:

Frontiers in Cellular & Infection Microbiology, 2012, v. 2, p. 1, doi. 10.3389/fcimb.2012.00089

By:

Aravind, L.;
Anantharaman, Vivek;
Dapeng Zhang;
de Souza, Robson F.;
Iyer, Lakshminarayan M.

Publication type:

Article

Novel autoproteolytic and DNA-damage sensing components in the bacterial SOS response and oxidized methylcytosine-induced eukaryotic DNA demethylation systems.

Published in:

Biology Direct, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1745-6150-8-20

By:

Aravind, L.;
Anand, Swadha;
Iyer, Lakshminarayan M.

Publication type:

Article

Two novel PIWI families: roles in inter-genomic conflicts in bacteria and Mediator-dependent modulation of transcription in eukaryotes.

Published in:

Biology Direct, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1745-6150-8-13

By:

Maxwell Burroughs, A.;
Iyer, Lakshminarayan M.;
Aravind, L.

Publication type:

Article

ALOG domains: provenance of plant homeotic and developmental regulators from the DNA-binding domain of a novel class of DIRS1-type retroposons.

Published in:

Biology Direct, 2012, v. 7, n. 1, p. 39, doi. 10.1186/1745-6150-7-39

By:

Iyer, Lakshminarayan M.;
Aravind, L.

Publication type:

Article

Polymorphic toxin systems: Comprehensive characterization of trafficking modes, processing, mechanisms of action, immunity and ecology using comparative genomics.

Published in:

Biology Direct, 2012, v. 7, n. 1, p. 18, doi. 10.1186/1745-6150-7-18

By:

Dapeng Zhang;
de Souza, Robson F.;
Anantharaman, Vivek;
Iyer, Lakshminarayan M.;
Aravind, L.;
A. M.;
F. E.;
I. Z.

Publication type:

Article

Predicted class-I aminoacyl tRNA synthetase-like proteins in non-ribosomal peptide synthesis.

Published in:

Biology Direct, 2010, v. 5, p. 48, doi. 10.1186/1745-6150-5-48

By:

Aravind, L.;
de Souza, Robson F.;
Iyer, Lakshminarayan M.

Publication type:

Article

Presence of a classical RRM-fold palm domain inThg1-type 3'- 5'nucleic acid polymerases and theorigin of the GGDEF and CRISPR polymerasedomains.

Published in:

Biology Direct, 2010, v. 5, p. 43, doi. 10.1186/1745-6150-5-43

By:

Anantharaman, Vivek;
Iyer, Lakshminarayan M.;
Aravind, L.

Publication type:

Article

MutL homologs in restriction-modification systems and the origin of eukaryotic MORC ATPases.

Published in:

Biology Direct, 2008, v. 3, p. 1, doi. 10.1186/1745-6150-3-8

By:

Iyer, Lakshminarayan M.;
Abhiman, Saraswathi;
Aravind, L.

Publication type:

Article

A novel superfamily containing the β-grasp fold involved in binding diverse soluble ligands.

Published in:

Biology Direct, 2007, v. 2, p. 4, doi. 10.1186/1745-6150-2-4

By:

Burroughs, A. Maxwell;
Balaji, S.;
Iyer, Lakshminarayan M.;
Aravind, L.

Publication type:

Article

Small but versatile: the extraordinary functional and structural diversity of the β-grasp fold.

Published in:

Biology Direct, 2007, v. 2, p. 18, doi. 10.1186/1745-6150-2-18

By:

Burroughs, A. Maxwell;
Balaji, S.;
Iyer, Lakshminarayan M.;
Aravind, L.

Publication type:

Article

Corrigendum: The cyl Genes Reveal the Biosynthetic and Evolutionary Origins of the Group B Streptococcus Hemolytic Lipid, Granadaene.

Published in:

2020

By:

Armistead, Blair;
Whidbey, Christopher;
Iyer, Lakshminarayan M.;
Herrero-Foncubierta, Pilar;
Quach, Phoenicia;
Haidour, Ali;
Aravind, L.;
Cuerva, Juan Manuel;
Jaspan, Heather B.;
Rajagopal, Lakshmi

Publication type:

Correction Notice

The cyl Genes Reveal the Biosynthetic and Evolutionary Origins of the Group B Streptococcus Hemolytic Lipid, Granadaene.

Published in:

Frontiers in Microbiology, 2020, v. 10, p. 1, doi. 10.3389/fmicb.2019.03123

By:

Armistead, Blair;
Whidbey, Christopher;
Iyer, Lakshminarayan M.;
Herrero-Foncubierta, Pilar;
Quach, Phoenicia;
Haidour, Ali;
Aravind, L.;
Cuerva, Juan Manuel;
Jaspan, Heather B.;
Rajagopal, Lakshmi

Publication type:

Article

Natural history of the E1-like superfamily: Implication for adenylation, sulfur transfer, and ubiquitin conjugation.

Published in:

Proteins, 2009, v. 75, n. 4, p. 895, doi. 10.1002/prot.22298

By:

Burroughs, A. Maxwell;
Iyer, Lakshminarayan M.;
Aravind, L.

Publication type:

Article

The emergence of catalytic and structural diversity within the beta-clip fold.

Published in:

Proteins, 2004, v. 55, n. 4, p. 977, doi. 10.1002/prot.20076

By:

Iyer, Lakshminarayan M.;
Aravind, L.

Publication type:

Article

Adaptations of the helix-grip fold for ligand binding and catalysis in the START domain superfamily.

Published in:

Proteins, 2001, v. 43, n. 2, p. 134, doi. 10.1002/1097-0134(20010501)43:2<134::AID-PROT1025>3.0.CO;2-I

By:

Iyer, Lakshminarayan M.;
Koonin, Eugene V.;
Aravind, L.

Publication type:

Article

Assessment of penetrance and expressivity of RNAi-mediated silencing of the Arabidopsis phytoene desaturase gene.

Published in:

New Phytologist, 2005, v. 167, n. 3, p. 751, doi. 10.1111/j.1469-8137.2005.01454.x

By:

Wang, Tao;
Iyer, Lakshminarayan M.;
Pancholy, Rakesh;
Shi, Xiangyu;
Hall, Timothy C.

Publication type:

Article

Adenine methylation in eukaryotes: Apprehending the complex evolutionary history and functional potential of an epigenetic modification.

Published in:

BioEssays, 2016, v. 38, n. 1, p. 27, doi. 10.1002/bies.201500104

By:

Iyer, Lakshminarayan M.;
Dapeng Zhang;
Aravind, L.

Publication type:

Article

The HARE-HTH and associated domains.

Published in:

Cell Cycle, 2012, v. 11, n. 1, p. 119, doi. 10.4161/cc.11.1.18475

By:

Aravind, L.;
Iyer, Lakshminarayan M.

Publication type:

Article

A sequence-specific RNA acetylation catalyst Open Access.

Published in:

Nucleic Acids Research, 2025, v. 53, n. 6, p. 1, doi. 10.1093/nar/gkaf217

By:

Thalalla Gamage, Supuni;
Howpay Manage, Shereen;
Sas-Chen, Aldema;
Nir, Ronit;
Burkhart, Brett W;
Jhulki, Isita;
Link, Courtney N;
Penikalapati, Manini S;
Jones, Jane E;
Iyer, Lakshminarayan M;
Aravind, L;
Santangelo, Thomas J;
Schwartz, Schraga;
Meier, Jordan L

Publication type:

Article

Functionally comparable but evolutionarily distinct nucleotide-targeting effectors help identify conserved paradigms across diverse immune systems.

Published in:

Nucleic Acids Research, 2023, v. 51, n. 21, p. 11479, doi. 10.1093/nar/gkad879

By:

Nicastro, Gianlucca G;
Burroughs, A Maxwell;
Iyer, Lakshminarayan M;
Aravind, L

Publication type:

Article

Comprehensive classification of ABC ATPases and their functional radiation in nucleoprotein dynamics and biological conflict systems.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 18, p. 10045, doi. 10.1093/nar/gkaa726

By:

Krishnan, Arunkumar;
Burroughs, A Maxwell;
Iyer, Lakshminarayan M;
Aravind, L

Publication type:

Article

Multiple enzymatic activities of ParB/Srx superfamily mediate sexual conflict among conjugative plasmids.

Published in:

Nature Communications, 2014, v. 5, n. 10, p. 1, doi. 10.1038/ncomms6322

By:

Maindola, Priyank;
Raina, Rahul;
Goyal, Parveen;
Atmakuri, Krishnamohan;
Ojha, Abhishek;
Gupta, Sourabh;
Christie, Peter J.;
Iyer, Lakshminarayan M.;
Aravind, L.;
Arockiasamy, Arulandu

Publication type:

Article

Apprehending the NAD + –ADPr-Dependent Systems in the Virus World.

Published in:

Viruses (1999-4915), 2022, v. 14, n. 9, p. 1977, doi. 10.3390/v14091977

By:

Iyer, Lakshminarayan M.;
Burroughs, A. Maxwell;
Anantharaman, Vivek;
Aravind, L.

Publication type:

Article

Jumbo Phages: A Comparative Genomic Overview of Core Functions and Adaptions for Biological Conflicts.

Published in:

Viruses (1999-4915), 2021, v. 13, n. 1, p. 63, doi. 10.3390/v13010063

By:

M. Iyer, Lakshminarayan;
Anantharaman, Vivek;
Krishnan, Arunkumar;
Burroughs, A. Maxwell;
Aravind, L.;
Thomas, Julie;
Black, Lindsay

Publication type:

Article

Comparative genomics of the FtsK–HerA superfamily of pumping ATPases: implications for the origins of chromosome segregation, cell division and viral capsid packaging.

Published in:

Nucleic Acids Research, 2004, v. 32, n. 17, p. 5260, doi. 10.1093/nar/gkh828

By:

Iyer, Lakshminarayan M.;
Makarova, Kira S.;
Koonin, Eugene V.;
Aravind, L.

Publication type:

Article

Detection of novel members, structure–function analysis and evolutionary classification of the 2H phosphoesterase superfamily.

Published in:

Nucleic Acids Research, 2002, v. 30, n. 23, p. 5229, doi. 10.1093/nar/gkf645

By:

Mazumder, Raja;
Iyer, Lakshminarayan M.;
Vasudevan, Sona;
Aravind, L.

Publication type:

Article

Prediction of novel families of enzymes involved in oxidative and other complex modifications of bases in nucleic acids.

Published in:

Cell Cycle, 2009, v. 8, n. 11, p. 1698, doi. 10.4161/cc.8.11.8580

By:

Iyer, Lakshminarayan M.;
Tahiliani, Mamta;
Rao, Anjana;
Aravind, L.

Publication type:

Article

Domain Architectures of the Scm3p Protein Provide Insights into Centromere Function and Evolution.

Published in:

Cell Cycle, 2007, v. 6, n. 20, p. 2511, doi. 10.4161/cc.6.20.4793

By:

Aravind, L.;
Iyer, Lakshminarayan M.;
Wu, Carl

Publication type:

Article

Estimating the Prevalence and Regulatory Potential of the Telomere Looping Effect in Yeast Transcription Regulation.

Published in:

Cell Cycle, 2006, v. 5, n. 20, p. 2354, doi. 10.4161/cc.5.20.3386

By:

Babu, M. Madan;
Balaji, S.;
Iyer, Lakshminarayan. M.;
Aravind, L.

Publication type:

Article

The HIRAN Domain and Recruitment of Chromatin Remodeling and Repair Activities to Damaged DNA.

Published in:

Cell Cycle, 2006, v. 5, n. 7, p. 775, doi. 10.4161/cc.5.7.2629

By:

Iyer, Lakshminarayan M.;
Babu, M. Madan;
Aravind, L.

Publication type:

Article

Novel Predicted Peptidases with a Potential Role in the Ubiquitin Signaling Pathway.

Published in:

Cell Cycle, 2004, v. 3, n. 11, p. 1440, doi. 10.4161/cc.3.11.1206

By:

Iyer, Lakshminarayan M.;
Koonin, Eugene V.;
Aravind, L.

Publication type:

Article

Evolutionary connection between the catalytic subunits of DNA-dependent RNA polymerases and eukaryotic RNA-dependent RNA polymerases and the origin of RNA polymerases.

Published in:

BMC Structural Biology, 2003, v. 3, p. 1, doi. 10.1186/1472-6807-3-1

By:

Iyer, Lakshminarayan M.;
Koonin, Eugene V.;
Aravind, L.

Publication type:

Article

Functional Innovation in the Evolution of the Calcium-Dependent System of the Eukaryotic Endoplasmic Reticulum.

Published in:

Frontiers in Genetics, 2020, p. 1, doi. 10.3389/fgene.2020.00034

By:

Schäffer, Daniel E.;
Iyer, Lakshminarayan M.;
Burroughs, A. Maxwell;
Aravind, L.

Publication type:

Article

A Nonhemolytic Group B Streptococcus Strain Exhibits Hypervirulence.

Published in:

2018

By:

Gendrin, Claire;
Vornhagen, Jay;
Armistead, Blair;
Singh, Pallavi;
Whidbey, Christopher;
Merillat, Sean;
Knupp, David;
Parker, Robert;
Rogers, Lisa M.;
Quach, Phoenicia;
Iyer, Lakshminarayan M.;
Aravind, L.;
Manning, Shannon D.;
Aronoff, David M.;
Rajagopal, Lakshmi

Publication type:

journal article

Transposons to toxins: the provenance, architecture and diversification of a widespread class of eukaryotic effectors.

Published in:

Nucleic Acids Research, 2016, v. 44, n. 8, p. 3513, doi. 10.1093/nar/gkw221

By:

Zhang, Dapeng;
Burroughs, A. Maxwell;
Vidal, Newton D.;
Iyer, Lakshminarayan M.;
Aravind, L.

Publication type:

Article

Comparative genomic analyses reveal a vast, novel network of nucleotide-centric systems in biological conflicts, immunity and signaling.

Published in:

Nucleic Acids Research, 2015, v. 43, n. 22, p. 10633, doi. 10.1093/nar/gkv1267

By:

Burroughs, A. Maxwell;
Zhang, Dapeng;
Schäffer, Daniel E.;
Iyer, Lakshminarayan M.;
Aravind, L.

Publication type:

Article

Computational identification of novel biochemical systems involved in oxidation, glycosylation and other complex modifications of bases in DNA.

Published in:

Nucleic Acids Research, 2013, v. 41, n. 16, p. 7635, doi. 10.1093/nar/gkt573

By:

Iyer, Lakshminarayan M.;
Zhang, Dapeng;
Maxwell Burroughs, A.;
Aravind, L.

Publication type:

Article

Evolution of the deaminase fold and multiple origins of eukaryotic editing and mutagenic nucleic acid deaminases from bacterial toxin systems.

Published in:

Nucleic Acids Research, 2011, v. 39, n. 22, p. 9473, doi. 10.1093/nar/gkr691

By:

Iyer, Lakshminarayan M.;
Zhang, Dapeng;
Rogozin, Igor B.;
Aravind, L.

Publication type:

Article

A novel immunity system for bacterial nucleic acid degrading toxins and its recruitment in various eukaryotic and DNA viral systems.

Published in:

Nucleic Acids Research, 2011, v. 39, n. 11, p. 4532, doi. 10.1093/nar/gkr036

By:

Zhang, Dapeng;
Iyer, Lakshminarayan M.;
Aravind, L.

Publication type:

Article

Origin and evolution of peptide-modifying dioxygenases and identification of the wybutosine hydroxylase/hydroperoxidase.

Published in:

Nucleic Acids Research, 2010, v. 38, n. 16, p. 5261, doi. 10.1093/nar/gkq265

By:

Iyer, Lakshminarayan M.;
Abhiman, Saraswathi;
de Souza, Robson F.;
Aravind, L.

Publication type:

Article