Works by Iyengar, Ravi

Results: 77

Systems pharmacology of complex diseases.

Published in:

Annals of the New York Academy of Sciences, 2011, v. 1245, n. 1, p. E1, doi. 10.1111/j.1749-6632.2011.06382.x

By:

Hansen, Jens;
Zhao, Shan;
Iyengar, Ravi

Publication type:

Article

Stimulation and inhibition of adenylyl cyclases mediated by distinct regulatory proteins.

Published in:

Nature, 1983, v. 302, n. 5910, p. 706, doi. 10.1038/302706a0

By:

Hildebrandt, John D.;
Sekura, Ronald D.;
Codina, Juan;
Iyengar, Ravi;
Manclark, Charles R.;
Birnbaumer, Lutz

Publication type:

Article

Small Molecule-Mediated Directed Differentiation of Human Embryonic Stem Cells Toward Ventricular Cardiomyocytes.

Published in:

Stem Cells Translational Medicine, 2014, v. 3, n. 1, p. 18, doi. 10.5966/sctm.2013-0110

By:

KARAKIKES, IOANNIS;
SENYEI, GRANT D.;
HANSEN, JENS;
CHI-WING KONG;
AZELOGLU, EVREN U.;
STILLITANO, FRANCESCA;
LIEU, DEBORAH K.;
JIAXIAN WANG;
LIHUAN REN;
HULOT, JEAN-SEBASTIEN;
IYENGAR, RAVI;
LI, RONALD A.;
HAJJAR, ROGER J.

Publication type:

Article

Merging Systems Biology with Pharmacodynamics.

Published in:

Science Translational Medicine, 2012, v. 4, n. 126, p. 1, doi. 10.1126/scitranslmed.3003563

By:

Iyengar, Ravi;
Zhao, Shan;
Chung, Seung-Wook;
Mager, Donald E.;
Gallo, James M.

Publication type:

Article

Solubilization of an angiotensin II binding site from rat liver.

Published in:

Archives of Pharmacal Research, 1991, v. 14, n. 3, p. 231, doi. 10.1007/BF02876861

By:

Chung, Sung-Hyun;
Iyengar, Ravi

Publication type:

Article

Genomic signatures defining responsiveness to allopurinol and combination therapy for lung cancer identified by systems therapeutics analyses.

Published in:

Molecular Oncology, 2019, v. 13, n. 8, p. 1725, doi. 10.1002/1878-0261.12521

By:

Tavassoly, Iman;
Hu, Yuan;
Zhao, Shan;
Mariottini, Chiara;
Boran, Aislyn;
Chen, Yibang;
Li, Lisa;
Tolentino, Rosa E.;
Jayaraman, Gomathi;
Goldfarb, Joseph;
Gallo, James;
Iyengar, Ravi

Publication type:

Article

▪▪▪Report on EU–USA Workshop: How Systems Biology Can Advance Cancer Research (27 October 2008)

Published in:

2009

By:

Aebersold, Ruedi;
Auffray, Charles;
Baney, Erin;
Barillot, Emmanuel;
Brazma, Alvis;
Brett, Catherine;
Brunak, Søren;
Butte, Atul;
Califano, Andrea;
Celis, Julio;
Čufer, Tanja;
Ferrell, James;
Galas, David;
Gallahan, Daniel;
Gatenby, Robert;
Goldbeter, Albert;
Hace, Nataša;
Henney, Adriano;
Hood, Lee;
Iyengar, Ravi

Publication type:

Proceeding

Endothelial dysfunction drives aneurysm development in Marfan syndrome.

Published in:

FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R5672

By:

Cantalupo, Anna;
Asano, Keiichi;
Hansen, Jens;
Halabi, Carmen;
Mecham, Robert;
Iyengar, Ravi;
Ramirez, Francesco

Publication type:

Article

AT1R blockade together with AT2R stimulation prevents aortic aneurysm in mice with progressively severe Marfan syndrome.

Published in:

FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R5562

By:

Asano, Keiichi;
Cantalupo, Anna;
Hansen, Jens;
Spronck, Bart;
Humphrey, Jay D.;
Iyengar, Ravi;
Ramirez, Francesco

Publication type:

Article

Systems approach to explore components and interactions in the presynapse.

Published in:

Proteomics, 2009, v. 9, n. 12, p. 3303, doi. 10.1002/pmic.200800767

By:

Abul-Husn, Noura S.;
Bushlin, Ittai;
Morón, José A.;
Jenkins, Sherry L.;
Dolios, Georgia;
Wang, Rong;
Iyengar, Ravi;
Ma'ayan, Avi;
Devi, Lakshmi A.

Publication type:

Article

Proteomic cellular signatures of kinase inhibitor-induced cardiotoxicity.

Published in:

Scientific Data, 2022, v. 9, n. 1, p. 1, doi. 10.1038/s41597-021-01114-3

By:

Xiong, Yuguang;
Liu, Tong;
Chen, Tong;
Hansen, Jens;
Hu, Bin;
Chen, Yibang;
Jayaraman, Gomathi;
Schürer, Stephan;
Vidovic, Dusica;
Goldfarb, Joseph;
Sobie, Eric A.;
Birtwistle, Marc R.;
Iyengar, Ravi;
Li, Hong;
Azeloglu, Evren U.

Publication type:

Article

Spinal cord injury regulates circular RNA expression in axons.

Published in:

Frontiers in Molecular Neuroscience, 2023, p. 1, doi. 10.3389/fnmol.2023.1183315

By:

Siddiq, Mustafa M.;
Toro, Carlos A.;
Johnson, Nicholas P.;
Hansen, Jens;
Yuguang Xiong;
Mellado, Wilfredo;
Tolentino, Rosa E.;
Johnson, Kaitlin;
Jayaraman, Gomathi;
Suhail, Zaara;
Harlow, Lauren;
Jinye Dai;
Beaumont, Kristin G.;
Sebra, Robert;
Willis, Dianna E.;
Cardozo, Christopher P.;
Iyengar, Ravi

Publication type:

Article

Mitogen-Activated Protein Kinase Upregulates the Dendritic Translation Machinery in Long-Term Potentiation by Controlling the Mammalian Target of Rapamycin Pathway.

Published in:

Journal of Neuroscience, 2007, v. 27, n. 22, p. 5885, doi. 10.1523/JNEUROSCI.4548-06.2007

By:

Tsokas, Panayiotis;
Tao Ma;
Iyengar, Ravi;
Landau, Emmanuel M.;
Blitzer, Robert D.

Publication type:

Article

Local Protein Synthesis Mediates a Rapid Increase in Dendritic Elongation Factor 1A after Induction of Late Long-Term Potentiation.

Published in:

Journal of Neuroscience, 2005, v. 25, n. 24, p. 5833, doi. 10.1523/JNEUROSCI.0599-05.2005

By:

Tsokas, Panayiotis;
Grace, Elizabeth A.;
PokMan Chan;
Tao Ma;
Sealfon, Stuart C.;
Iyengar, Ravi;
Landau, Emmanuel M.;
Blitzer, Robert D.

Publication type:

Article

Modelling spatio-temporal interactions within the cell.

Published in:

Journal of Biosciences, 2007, v. 32, n. 1, p. 157, doi. 10.1007/s12038-007-0014-3

By:

Rangamani, Padmini;
Iyengar, Ravi

Publication type:

Article

Fragility of foot process morphology in kidney podocytes arises from chaotic spatial propagation of cytoskeletal instability.

Published in:

PLoS Computational Biology, 2017, v. 13, n. 3, p. 1, doi. 10.1371/journal.pcbi.1005433

By:

Falkenberg, Cibele V.;
Azeloglu, Evren U.;
Stothers, Mark;
Deerinck, Thomas J.;
Chen, Yibang;
He, John C.;
Ellisman, Mark H.;
Hone, James C.;
Iyengar, Ravi;
Loew, Leslie M.

Publication type:

Article

Nef stimulates proliferation of glomerular podocytes through activation of Src-dependent Stat3 and MAPK1,2 pathways.

Published in:

2004

By:

He, John Cijiang;
Husain, Mohammad;
Sunamoto, Masaaki;
D'Agati, Vivette D;
Klotman, Mary E;
Iyengar, Ravi;
Klotman, Paul E

Publication type:

journal article

Nef stimulates proliferation of glomerular podocytes through activation of Src- dependent Stat3 and MAPK1,2 pathways.

Published in:

Journal of Clinical Investigation, 2004, v. 114, n. 5, p. 643, doi. 10.1172/JCI200421004

By:

Cijiang He, John;
Husain, Mohammad;
Sunamoto, Masaaki;
D'gati, Vivette D.;
Klotman, Mary E.;
Iyengar, Ravi;
Klotman, Paul E.

Publication type:

Article

AVIS: AJAX viewer of interactive signaling networks.

Published in:

Bioinformatics, 2007, v. 23, n. 20, p. 2803, doi. 10.1093/bioinformatics/btm444

By:

Berger, Seth I.;
Iyengar, Ravi;
Ma'ayan, Avi

Publication type:

Article

From transcriptomics to digital twins of organ function.

Published in:

Frontiers in Cell & Developmental Biology, 2024, p. 1, doi. 10.3389/fcell.2024.1240384

By:

Hansen, Jens;
Jain, Abhinav R.;
Nenov, Philip;
Robinson, Peter N.;
Iyengar, Ravi

Publication type:

Article

Relating individual cell division events to single-cell ERK and Akt activity time courses.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-23071-6

By:

Stern, Alan D.;
Smith, Gregory R.;
Santos, Luis C.;
Sarmah, Deepraj;
Zhang, Xiang;
Lu, Xiaoming;
Iuricich, Federico;
Pandey, Gaurav;
Iyengar, Ravi;
Birtwistle, Marc R.

Publication type:

Article

Fibrillin-1 deficiency in the outer perichondrium causes longitudinal bone overgrowth in mice with Marfan syndrome.

Published in:

Human Molecular Genetics, 2022, v. 31, n. 19, p. 3281, doi. 10.1093/hmg/ddac107

By:

Sedes, Lauriane;
Wondimu, Elisa;
Crockett, Brittany;
Hansen, Jens;
Cantalupo, Anna;
Asano, Keiichi;
Iyengar, Ravi;
Rifkin, Daniel B;
Smaldone, Silvia;
Ramirez, Francesco

Publication type:

Article

Sequence, Structure, and Functional Space of Drosophila De Novo Proteins.

Published in:

Genome Biology & Evolution, 2024, v. 16, n. 8, p. 1, doi. 10.1093/gbe/evae176

By:

Middendorf, Lasse;
Iyengar, Bharat Ravi;
Eicholt, Lars A

Publication type:

Article

Modeling Length Changes in De Novo Open Reading Frames during Neutral Evolution.

Published in:

Genome Biology & Evolution, 2024, v. 16, n. 7, p. 1, doi. 10.1093/gbe/evae129

By:

Lebherz, Marie Kristin;
Iyengar, Bharat Ravi;
Bornberg-Bauer, Erich

Publication type:

Article

The Human ApoE4 Variant Reduces Functional Recovery and Neuronal Sprouting After Incomplete Spinal Cord Injury in Male Mice.

Published in:

Frontiers in Cellular Neuroscience, 2021, v. 15, p. N.PAG, doi. 10.3389/fncel.2021.626192

By:

Toro, Carlos A.;
Hansen, Jens;
Siddiq, Mustafa M.;
Johnson, Kaitlin;
Zhao, Wei;
Azulai, Daniella;
Das, Dibash K.;
Bauman, William;
Sebra, Robert;
Cai, Dongming;
Iyengar, Ravi;
Cardozo, Christopher P.

Publication type:

Article

OSCI: standardized stem cell ontology representation and use cases for stem cell investigation.

Published in:

BMC Bioinformatics, 2019, v. 20, n. 1, p. 237, doi. 10.1186/s12859-019-2723-7

By:

He, Yongqun;
Duncan, William D.;
Cooper, Daniel J.;
Hansen, Jens;
Iyengar, Ravi;
Ong, Edison;
Walker, Kendal;
Tibi, Omar;
Smith, Sam;
Serra, Lucas M.;
Zheng, Jie;
Sarntivijai, Sirarat;
Schürer, Stephan;
O'Shea, K. Sue;
Diehl, Alexander D.

Publication type:

Article

Systems Pharmacology of Adverse Event Mitigation by Drug Combinations.

Published in:

Science Translational Medicine, 2013, v. 5, n. 206, p. 1, doi. 10.1126/scitranslmed.3006548

By:

Shan Zhao;
Tomohiro Nishimura;
Yibang Chen;
Azeloglu, Evren U.;
Gottesman, Omri;
Giannarelli, Chiara;
Zafar, Mohammad U.;
Benard, Ludovic;
Badimon, Juan J.;
Hajjar, Roger J.;
Goldfarb, Joseph;
Iyengar, Ravi

Publication type:

Article

Memory discrimination is promoted by the expression of the transcription repressor WT1 in the dentate gyrus.

Published in:

Frontiers in Behavioral Neuroscience, 2023, p. 1, doi. 10.3389/fnbeh.2023.1130840

By:

Munari, Leonardo;
Patel, Vishwendra;
Johnson, Nicholas;
Mariottini, Chiara;
Prabha, Som;
Blitzer, Robert D.;
Iyengar, Ravi

Publication type:

Article

Neutral Models of De Novo Gene Emergence Suggest that Gene Evolution has a Preferred Trajectory.

Published in:

Molecular Biology & Evolution, 2023, v. 40, n. 4, p. 1, doi. 10.1093/molbev/msad079

By:

Iyengar, Bharat Ravi;
Bornberg-Bauer, Erich

Publication type:

Article

GroEL/S Overexpression Helps to Purge Deleterious Mutations and Reduce Genetic Diversity during Adaptive Protein Evolution.

Published in:

Molecular Biology & Evolution, 2022, v. 39, n. 6, p. 1, doi. 10.1093/molbev/msac047

By:

Iyengar, Bharat Ravi;
Wagner, Andreas

Publication type:

Article

Network analyses in systems pharmacology.

Published in:

Bioinformatics, 2009, v. 25, n. 19, p. 2466, doi. 10.1093/bioinformatics/btp465

By:

Berger, Seth I.;
Iyengar, Ravi

Publication type:

Article

A direct experimental test of Ohno's hypothesis.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.97216

By:

Mihajlovic, Ljiljana;
Iyengar, Bharat Ravi;
Baier, Florian;
Barbier, Içvara;
Iwaszkiewicz, Justyna;
Zoete, Vincent;
Wagner, Andreas;
Schaerli, Yolanda

Publication type:

Article

Geometric principles of second messenger dynamics in dendritic spines.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-48028-0

By:

Cugno, Andrea;
Bartol, Thomas M.;
Sejnowski, Terrence J.;
Iyengar, Ravi;
Rangamani, Padmini

Publication type:

Article

Modeling of signaling networks.

Published in:

BioEssays, 2002, v. 24, n. 12, p. 1110, doi. 10.1002/bies.1154

By:

Neves, Susana R.;
Iyengar, Ravi

Publication type:

Article

SNAVI: Desktop application for analysis and visualization of large-scale signaling networks.

Published in:

BMC Systems Biology, 2009, v. 3, p. 1, doi. 10.1186/1752-0509-3-10

By:

Ma'ayan, Avi;
Jenkins, Sherry L.;
Webb, Ryan L.;
Berger, Seth I.;
Purushothaman, Sudarshan P.;
Abul-Husn, Noura S.;
Posner, Jeremy M.;
Flores, Tony;
Iyengar, Ravi

Publication type:

Article

Retinoic Acid Utilizes CREB and USF1 in a Transcriptional Feed-Forward Loop in Order To Stimulate MKP1 Expression in Human Immunodeficiency Virus-Infected Podocytes.

Published in:

Molecular & Cellular Biology, 2008, v. 28, n. 18, p. 5785, doi. 10.1128/MCB.00245-08

By:

Ting-Chi Lu;
Zhaohui Wang;
Xiaobei Feng;
Chuang, Peter;
Wei Fang;
Yibang Chen;
Neves, Susana;
Maayan, Avi;
Huabao Xiong;
Yusen Liu;
Iyengar, Ravi;
Klotman, Paul E.;
He, John Cijiang

Publication type:

Article

Phosphatidylinositol-4,5-bisphosphate regulates epidermal growth factor receptor activation.

Published in:

Pflügers Archiv: European Journal of Physiology, 2011, v. 461, n. 3, p. 387, doi. 10.1007/s00424-010-0904-3

By:

Michailidis, Ioannis;
Rusinova, Radda;
Georgakopoulos, Anastasios;
Chen, Yibang;
Iyengar, Ravi;
Robakis, Nikolaos;
Logothetis, Diomedes;
Baki, Lia

Publication type:

Article

Validating Antibodies for Quantitative Western Blot Measurements with Microwestern Array.

Published in:

Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-29436-0

By:

Koch, Rick J.;
Barrette, Anne Marie;
Stern, Alan D.;
Hu, Bin;
Bouhaddou, Mehdi;
Azeloglu, Evren U.;
Iyengar, Ravi;
Birtwistle, Marc R.

Publication type:

Article

Systems Pharmacology of Arrhythmias.

Published in:

Science Signaling, 2010, v. 3, n. 121, p. 1, doi. 10.1126/scisignal.2000723

By:

Berger, Seth I.;
Ma'ayan, Avi;
Iyengar, Ravi

Publication type:

Article

Systems Pharmacology of Arrhythmias.

Published in:

Science Signaling, 2010, v. 3, n. 118, p. 1, doi. 10.1126/scisignal.2000723

By:

Berger, Seth I.;
Ma'ayan, Avi;
Iyengar, Ravi

Publication type:

Article

Why We Need Quantitative Dynamic Models.

Published in:

Science Signaling, 2009, v. 2, n. 64, p. 1, doi. 10.1126/scisignal.264eg3

By:

Iyengar, Ravi

Publication type:

Article

Neuro2A Differentiation by Gα<sub>i/o</sub> Pathway.

Published in:

Science Signaling, 2009, v. 2, n. 54, p. 1, doi. 10.1126/scisignal.254cm1

By:

Ma'ayan, Avi;
Jenkins, Sherry L.;
Barash, Alexander;
Iyengar, Ravi

Publication type:

Article

Using Web-Based Discussion Forums as a Model of the Peer-Review Process and a Tool for Assessment.

Published in:

Science Signaling, 2008, v. 1, n. 9, p. 1, doi. 10.1126/stke.19tr2

By:

Jenkins, Sherry L.;
Iyengar, Ravi;
Diverse-Pierluissi, Maria A.;
Chan, Andrew M.;
Devi, Lakshmi A.;
Sobie, Eric A.;
Ting, Adrian T.;
Weinstein, Daniel C.

Publication type:

Article

Quantitative Models of Mammalian Cell Signaling Pathways.

Published in:

Science Signaling, 2008, v. 1, n. 7, p. 1, doi. 10.1126/stke.17tr1

By:

Iyengar, Ravi

Publication type:

Article

Inpatient Glycemic Management in the Setting of Renal Insufficiency/Failure/Dialysis.

Published in:

2018

By:

Iyengar, Ravi;
Franzese, Jennifer;
Gianchandani, Roma

Publication type:

journal article

Role of the G<sub>o/i</sub> signaling network in the regulation of neurite outgrowth.

Published in:

Canadian Journal of Physiology & Pharmacology, 2006, v. 84, n. 7, p. 687, doi. 10.1139/Y06-025

By:

Cijiang He, John;
Neves, Susana R.;
Jordan, J. Dedrick;
Iyengar, Ravi

Publication type:

Article

Recovering Protein-Protein and Domain-Domain Interactions from Aggregation of IP-MS Proteomics of Coregulator Complexes.

Published in:

PLoS Computational Biology, 2011, v. 7, n. 12, p. 1, doi. 10.1371/journal.pcbi.1002319

By:

Mazloom, Amin R.;
Dannenfelser, Ruth;
Clark, Neil R.;
Grigoryan, Arsen V.;
Linder, Kathryn M.;
Cardozo, Timothy J.;
Bond, Julia C.;
Boran, Aislyn D. W.;
Iyengar, Ravi;
Malovannaya, Anna;
Lanz, Rainer B.;
Ma'ayan, Avi

Publication type:

Article

Specification of Spatial Relationships in Directed Graphs of Cell Signaling Networks.

Published in:

Annals of the New York Academy of Sciences, 2009, v. 1158, p. 44, doi. 10.1111/j.1749-6632.2008.03748.x

By:

Lipshtat, Azi;
Neves, Susana R.;
Iyengar, Ravi

Publication type:

Article

Computational Analysis of Isoform-Specific Signal Regulation by CEACAM1-A Cell Adhesion Molecule Expressed in PC12 Cells.

Published in:

Annals of the New York Academy of Sciences, 2002, v. 971, n. 1, p. 597, doi. 10.1111/j.1749-6632.2002.tb04536.x

By:

ÖBRINK, BJÖRN;
SAWA, HIROKI;
SCHEFFRAHN, INKA;
SINGER, BERNHARD B.;
SIGMUNDSSON, KRISTMUNDUR;
SUNDBERG, ULLA;
HEYMANN, ROBERT;
BEAUCHEMIN, NICOLE;
WENG, GEHZI;
RAM, PRAHLAD;
IYENGAR, RAVI

Publication type:

Article

From components to regulatory motifs in signalling networks.

Published in:

Briefings in Functional Genomics & Proteomics, 2006, v. 5, n. 1, p. 57, doi. 10.1093/bfgp/ell004

By:

Ma'ayan, Avi;
Iyengar, Ravi

Publication type:

Article