Works matching AU Ivanov, Nikolai V.


Results: 61
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    Impact of whole‐body versus nose‐only inhalation exposure systems on systemic, respiratory, and cardiovascular endpoints in a 2‐month cigarette smoke exposure study in the ApoE<sup>−/−</sup> mouse model.

    Published in:
    Journal of Applied Toxicology, 2021, v. 41, n. 10, p. 1598, doi. 10.1002/jat.4149
    By:
    • Kogel, Ulrike;
    • Wong, Ee Tsin;
    • Szostak, Justyna;
    • Tan, Wei Teck;
    • Lucci, Francesco;
    • Leroy, Patrice;
    • Titz, Bjoern;
    • Xiang, Yang;
    • Low, Tiffany;
    • Wong, Sin Kei;
    • Guedj, Emmanuel;
    • Ivanov, Nikolai V.;
    • Schlage, Walter K.;
    • Peitsch, Manuel C.;
    • Kuczaj, Arkadiusz;
    • Vanscheeuwijck, Patrick;
    • Hoeng, Julia
    Publication type:
    Article
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    Toxicoproteomics reveals an effect of clozapine on autophagy in human liver spheroids.

    Published in:
    Toxicology Mechanisms & Methods, 2023, v. 33, n. 5, p. 401, doi. 10.1080/15376516.2022.2156005
    By:
    • Nury, Catherine;
    • Merg, Celine;
    • Eb-Levadoux, Yvan;
    • Bovard, David;
    • Porchet, Matthieu;
    • Maranzano, Fabio;
    • Loncarevic, Isidora;
    • Tavalaei, Shahrzad;
    • Lize, Eleonore;
    • Demenescu, Ramona Liliana;
    • Yepiskoposyan, Hasmik;
    • Hoeng, Julia;
    • Ivanov, Nikolai V;
    • Renggli, Kasper;
    • Titz, Bjoern
    Publication type:
    Article
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    A framework for in vitro systems toxicology assessment of e-liquids.

    Published in:
    Toxicology Mechanisms & Methods, 2016, v. 26, n. 6, p. 392, doi. 10.3109/15376516.2016.1170251
    By:
    • Iskandar, Anita R.;
    • Gonzalez-Suarez, Ignacio;
    • Majeed, Shoaib;
    • Marescotti, Diego;
    • Sewer, Alain;
    • Xiang, Yang;
    • Leroy, Patrice;
    • Guedj, Emmanuel;
    • Mathis, Carole;
    • Schaller, Jean-Pierre;
    • Vanscheeuwijck, Patrick;
    • Frentzel, Stefan;
    • Martin, Florian;
    • Ivanov, Nikolai V.;
    • Peitsch, Manuel C.;
    • Hoeng, Julia
    Publication type:
    Article
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    Anatabine ameliorates intestinal inflammation and reduces the production of pro-inflammatory factors in a dextran sulfate sodium mouse model of colitis.

    Published in:
    Journal of Inflammation, 2020, v. 17, n. 1, p. N.PAG, doi. 10.1186/s12950-020-00260-6
    By:
    • Ruiz Castro, Pedro A.;
    • Kogel, Ulrike;
    • Lo Sasso, Giuseppe;
    • Phillips, Blaine W.;
    • Sewer, Alain;
    • Titz, Bjorn;
    • Garcia, Llenalia;
    • Kondylis, Athanasios;
    • Guedj, Emmanuel;
    • Peric, Dariusz;
    • Bornand, David;
    • Dulize, Remi;
    • Merg, Celine;
    • Corciulo, Maica;
    • Ivanov, Nikolai V.;
    • Peitsch, Manuel C.;
    • Hoeng, Julia
    Publication type:
    Article
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    Systems toxicology study reveals reduced impact of heated tobacco product aerosol extract relative to cigarette smoke on premature aging and exacerbation effects in aged aortic cells in vitro.

    Published in:
    Archives of Toxicology, 2021, v. 95, n. 10, p. 3341, doi. 10.1007/s00204-021-03123-y
    By:
    • Poussin, Carine;
    • van der Toorn, Marco;
    • Scheuner, Sophie;
    • Piault, Romain;
    • Kondylis, Athanasios;
    • Savioz, Rebecca;
    • Dulize, Rémi;
    • Peric, Dariusz;
    • Guedj, Emmanuel;
    • Maranzano, Fabio;
    • Merg, Celine;
    • Morelli, Moran;
    • Egesipe, Anne-Laure;
    • Johne, Stéphanie;
    • Majeed, Shoaib;
    • Pak, Claudius;
    • Schneider, Thomas;
    • Schlage, Walter K.;
    • Ivanov, Nikolai V.;
    • Peitsch, Manuel C.
    Publication type:
    Article
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    Evaluation of toxicity of aerosols from flavored e-liquids in Sprague–Dawley rats in a 90-day OECD inhalation study, complemented by transcriptomics analysis.

    Published in:
    Archives of Toxicology, 2020, v. 94, n. 6, p. 2179, doi. 10.1007/s00204-020-02759-6
    By:
    • Ho, Jenny;
    • Sciuscio, Davide;
    • Kogel, Ulrike;
    • Titz, Bjoern;
    • Leroy, Patrice;
    • Vuillaume, Gregory;
    • Talikka, Marja;
    • Martin, Elyette;
    • Pospisil, Pavel;
    • Lebrun, Stefan;
    • Xia, Wenhao;
    • Lee, Tom;
    • Chng, Yun Xuan;
    • Phillips, Blaine W.;
    • Veljkovic, Emilija;
    • Guedj, Emmanuel;
    • Xiang, Yang;
    • Ivanov, Nikolai V.;
    • Peitsch, Manuel C.;
    • Hoeng, Julia
    Publication type:
    Article
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    Application of a multi-layer systems toxicology framework for in vitro assessment of the biological effects of Classic Tobacco e-liquid and its corresponding aerosol using an e-cigarette device with MESH™ technology.

    Published in:
    Archives of Toxicology, 2019, v. 93, n. 11, p. 3229, doi. 10.1007/s00204-019-02565-9
    By:
    • Iskandar, Anita R.;
    • Zanetti, Filippo;
    • Marescotti, Diego;
    • Titz, Bjorn;
    • Sewer, Alain;
    • Kondylis, Athanasios;
    • Leroy, Patrice;
    • Belcastro, Vincenzo;
    • Torres, Laura Ortega;
    • Acali, Stefano;
    • Majeed, Shoaib;
    • Steiner, Sandro;
    • Trivedi, Keyur;
    • Guedj, Emmanuel;
    • Merg, Celine;
    • Schneider, Thomas;
    • Frentzel, Stefan;
    • Martin, Florian;
    • Ivanov, Nikolai V.;
    • Peitsch, Manuel C.
    Publication type:
    Article
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    Impact of 6-Month Exposure to Aerosols From Potential Modified Risk Tobacco Products Relative to Cigarette Smoke on the Rodent Gastrointestinal Tract.

    Published in:
    Frontiers in Microbiology, 2021, v. 12, p. 1, doi. 10.3389/fmicb.2021.587745
    By:
    • Battey, James N. D.;
    • Szostak, Justyna;
    • Phillips, Blaine;
    • Teng, Charles;
    • Tung, Ching Keong;
    • Lim, Wei Ting;
    • Yeo, Ying Shan;
    • Ouadi, Sonia;
    • Baumer, Karine;
    • Thomas, Jerome;
    • Martinis, Jacopo;
    • Sierro, Nicolas;
    • Ivanov, Nikolai V.;
    • Vanscheeuwijck, Patrick;
    • Peitsch, Manuel C.;
    • Hoeng, Julia
    Publication type:
    Article
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    Systems biology reveals anatabine to be an NRF2 activator.

    Published in:
    Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1011184
    By:
    • Messinis, Dimitris E.;
    • Poussin, Carine;
    • Latino, Diogo A. R. S.;
    • Eb-Levadoux, Yvan;
    • Dulize, Remi;
    • Peric, Dariusz;
    • Guedj, Emmanuel;
    • Titz, Bjoern;
    • Ivanov, Nikolai V.;
    • Peitsch, Manuel C.;
    • Hoeng, Julia
    Publication type:
    Article
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    Biological changes in C57BL/6 mice following 3 weeks of inhalation exposure to cigarette smoke or e-vapor aerosols.

    Published in:
    Inhalation Toxicology, 2018, v. 30, n. 13/14, p. 553, doi. 10.1080/08958378.2019.1576807
    By:
    • Lee, K. Monica;
    • Hoeng, Julia;
    • Harbo, Sam;
    • Kogel, Ulrike;
    • Gardner, William;
    • Oldham, Michael;
    • Benson, Eric;
    • Talikka, Marja;
    • Kondylis, Athanasios;
    • Martin, Florian;
    • Titz, Bjoern;
    • Ansari, Sam;
    • Trivedi, Keyur;
    • Guedj, Emmanuel;
    • Elamin, Ashraf;
    • Ivanov, Nikolai V.;
    • Vanscheeuwijck, Patrick;
    • Peitsch, Manuel C.;
    • McKinney, Willie J.
    Publication type:
    Article
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    Effects of cigarette smoke, cessation and switching to a candidate modified risk tobacco product on the liver in Apoe mice – a systems toxicology analysis.

    Published in:
    Inhalation Toxicology, 2016, v. 28, n. 5, p. 226, doi. 10.3109/08958378.2016.1150368
    By:
    • Lo Sasso, Giuseppe;
    • Titz, Bjoern;
    • Nury, Catherine;
    • Boué, Stéphanie;
    • Phillips, Blaine;
    • Belcastro, Vincenzo;
    • Schneider, Thomas;
    • Dijon, Sophie;
    • Baumer, Karine;
    • Peric, Daruisz;
    • Dulize, Remi;
    • Elamin, Ashraf;
    • Guedj, Emmanuel;
    • Buettner, Ansgar;
    • Leroy, Patrice;
    • Kleinhans, Samuel;
    • Vuillaume, Gregory;
    • Veljkovic, Emilija;
    • Ivanov, Nikolai V.;
    • Martin, Florian
    Publication type:
    Article
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    Pulmonary Delivery of Aerosolized Chloroquine and Hydroxychloroquine to Treat COVID-19: In Vitro Experimentation to Human Dosing Predictions.

    Published in:
    AAPS Journal, 2022, v. 24, n. 1, p. 1, doi. 10.1208/s12248-021-00666-x
    By:
    • Kolli, Aditya R.;
    • Semren, Tanja Zivkovic;
    • Bovard, David;
    • Majeed, Shoaib;
    • van der Toorn, Marco;
    • Scheuner, Sophie;
    • Guy, Philippe A.;
    • Kuczaj, Arkadiusz;
    • Mazurov, Anatoly;
    • Frentzel, Stefan;
    • Calvino-Martin, Florian;
    • Ivanov, Nikolai V.;
    • O’Mullane, John;
    • Peitsch, Manuel C.;
    • Hoeng, Julia
    Publication type:
    Article
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    A lower impact of an acute exposure to electronic cigarette aerosols than to cigarette smoke in human organotypic buccal and small airway cultures was demonstrated using systems toxicology assessment.

    Published in:
    2019
    By:
    • Iskandar, Anita R.;
    • Zanetti, Filippo;
    • Kondylis, Athanasios;
    • Martin, Florian;
    • Leroy, Patrice;
    • Majeed, Shoaib;
    • Steiner, Sandro;
    • Xiang, Yang;
    • Ortega Torres, Laura;
    • Trivedi, Keyur;
    • Guedj, Emmanuel;
    • Merg, Celine;
    • Frentzel, Stefan;
    • Ivanov, Nikolai V.;
    • Doshi, Utkarsh;
    • Lee, Kyeonghee Monica;
    • McKinney, Willie J.;
    • Peitsch, Manuel C.;
    • Hoeng, Julia;
    • McKinney, Willie J Jr
    Publication type:
    journal article
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    Evaluation of the Tobacco Heating System 2.2. Part 4: 90-day OECD 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects compared with cigarette smoke.

    Published in:
    Romanian Medical Journal, 2019, v. 66, n. 1, p. 70, doi. 10.1016/j.yrtph.2016.10.015
    By:
    • Ee Tsin Wong;
    • Kogel, Ulrike;
    • Veljkovic, Emilija;
    • Martin, Florian;
    • Yang Xiang;
    • Boue, Stephanie;
    • Vuillaume, Gregory;
    • Leroy, Patrice;
    • Guedj, Emmanuel;
    • Rodrigo, Gregory;
    • Ivanov, Nikolai V.;
    • Hoeng, Julia;
    • Peitsch, Manuel C.;
    • PatrickVanscheeuwijck
    Publication type:
    Article
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    The reduction of DSS-induced colitis severity in mice exposed to cigarette smoke is linked to immune modulation and microbial shifts.

    Published in:
    Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-60175-3
    By:
    • Lo Sasso, Giuseppe;
    • Phillips, Blaine W.;
    • Sewer, Alain;
    • Battey, James N. D.;
    • Kondylis, Athanasios;
    • Talikka, Marja;
    • Titz, Bjoern;
    • Guedj, Emmanuel;
    • Peric, Dariusz;
    • Bornand, David;
    • Dulize, Remi;
    • Merg, Celine;
    • Corciulo, Maica;
    • Ouadi, Sonia;
    • Yanuar, Rendy;
    • Tung, Ching Keong;
    • Ivanov, Nikolai V.;
    • Peitsch, Manuel C.;
    • Hoeng, Julia
    Publication type:
    Article
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    Crowdsourced benchmarking of taxonomic metagenome profilers: lessons learned from the sbv IMPROVER Microbiomics challenge.

    Published in:
    BMC Genomics, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s12864-022-08803-2
    By:
    • Poussin, Carine;
    • Khachatryan, Lusine;
    • Sierro, Nicolas;
    • Narsapuram, Vijay Kumar;
    • Meyer, Fernando;
    • Kaikala, Vinay;
    • Chawla, Vandna;
    • Muppirala, Usha;
    • Kumar, Sunil;
    • Belcastro, Vincenzo;
    • Battey, James N. D.;
    • Scotti, Elena;
    • Boué, Stéphanie;
    • McHardy, Alice C.;
    • Peitsch, Manuel C.;
    • Ivanov, Nikolai V.;
    • Hoeng, Julia
    Publication type:
    Article
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    GladiaTOX: GLobal Assessment of Dose-IndicAtor in TOXicology.

    Published in:
    Bioinformatics, 2019, v. 35, n. 20, p. 4190, doi. 10.1093/bioinformatics/btz187
    By:
    • Belcastro, Vincenzo;
    • Cano, Stephane;
    • Marescotti, Diego;
    • Acali, Stefano;
    • Poussin, Carine;
    • Gonzalez-Suarez, Ignacio;
    • Martin, Florian;
    • Bonjour, Filipe;
    • Ivanov, Nikolai V;
    • Peitsch, Manuel C;
    • Hoeng, Julia
    Publication type:
    Article
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    Results and lessons learned from the sbv IMPROVER metagenomics diagnostics for inflammatory bowel disease challenge.

    Published in:
    Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-33050-0
    By:
    • Khachatryan, Lusine;
    • Xiang, Yang;
    • Ivanov, Artem;
    • Glaab, Enrico;
    • Graham, Garrett;
    • Granata, Ilaria;
    • Giordano, Maurizio;
    • Maddalena, Lucia;
    • Piccirillo, Marina;
    • Manipur, Ichcha;
    • Baruzzo, Giacomo;
    • Cappellato, Marco;
    • Avot, Batiste;
    • Stan, Adrian;
    • Battey, James;
    • Lo Sasso, Giuseppe;
    • Boue, Stephanie;
    • Ivanov, Nikolai V.;
    • Peitsch, Manuel C.;
    • Hoeng, Julia
    Publication type:
    Article
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    How Complex Should an In Vitro Model Be? Evaluation of a Complex 3D Alveolar Model with Transcriptomic Data and Computational Biological Network Models.

    Published in:
    Altex, 2019, v. 36, n. 3, p. 388, doi. 10.14573/altex.1811221
    By:
    • Marescotti, Diego;
    • Serchi, Tommaso;
    • Luettich, Karsta;
    • Yang Xiang;
    • Moschini, Elisa;
    • Talikka, Marja;
    • Martin, Florian;
    • Baumer, Karine;
    • Dulize, Remi;
    • Peric, Dariusz;
    • Bornand, David;
    • Guedj, Emmanuel;
    • Sewer, Alain;
    • Cambier, Sebastien;
    • Contal, Servane;
    • Chary, Aline;
    • Gutleb, Arno C.;
    • Frentzel, Stefan;
    • Ivanov, Nikolai V.;
    • Peitsch, Manuel C.
    Publication type:
    Article
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