Works by Itaru Kojima

Results: 55

Return of the glucoreceptor: Glucose activates the glucose-sensing receptor T1R3 and facilitates metabolism in pancreatic β-cells.

Published in:

Journal of Diabetes Investigation, 2015, v. 6, n. 3, p. 256, doi. 10.1111/jdi.12304

By:

Kojima, Itaru;
Nakagawa, Yuko;
Ohtsu, Yoshiaki;
Hamano, Kunihisa;
Medina, Johan;
Nagasawa, Masahiro

Publication type:

Article

Reversal of streptozotocin-induced hyperglycemia by continuous supply of betacellulin in mice.

Published in:

Growth Factors, 2008, v. 26, n. 4, p. 173, doi. 10.1080/08977190802136854

By:

Yamamoto, Yoritsuna;
Yamada, Satoko;
Kodera, Tsutomu;
Hara, Akemi;
Motoyoshi, Kazuo;
Tanaka, Yuji;
Nagaoka, Tadahiro;
Seno, Masaharu;
Kojima, Itaru

Publication type:

Article

Translocation of a calcium-permeable cation channel induced by insulin-like growth factor-I.

Published in:

Nature Cell Biology, 1999, v. 1, n. 3, p. 165, doi. 10.1038/11086

By:

Kanzaki, Makoto;
Zhang, You-Qing;
Mashima, Hirosato;
Li, Lu;
Shibata, Hiroshi;
Kojima, Itaru

Publication type:

Article

T1R3 homomeric sweet taste receptor negatively regulates insulin-induced glucose transport through Gas-mediated microtubules disassembly in 3T3-L1 adipocytes.

Published in:

Endocrine Journal, 2022, v. 69, n. 5, p. 487, doi. 10.1507/endocrj.ej21-0661

By:

Yosuke Masubuchi;
Jinhui Ma;
Tomohiro Suzuki;
Itaru Kojima;
Takeshi Inagaki;
Hiroshi Shibata

Publication type:

Article

Sucralose, an activator of the glucose-sensing receptor, increases ATP by calcium-dependent and -independent mechanisms.

Published in:

Endocrine Journal, 2016, v. 63, n. 8, p. 715, doi. 10.1507/endocrj.ej16-0217

By:

Longfei Li;
Yoshiaki Ohtsu;
Yuko Nakagawa;
Katsuyoshi Masuda;
Itaru Kojima

Publication type:

Article

Expression of the glucose-sensing receptor T1R3 in pancreatic islet: changes in the expression levels in various nutritional and metabolic states.

Published in:

Endocrine Journal, 2014, v. 61, n. 8, p. 797, doi. 10.1507/endocrj.ej14-0221

By:

Medina, Anya;
Nakagawa, Yuko;
Ma, Jinhui;
Li, Longfei;
Hamano, Kunihisa;
Akimoto, Toshio;
Ninomiya, Yuzo;
Kojima, Itaru

Publication type:

Article

Glucose promotes its own metabolism by acting on the cell-surface glucose-sensing receptor T1R3.

Published in:

Endocrine Journal, 2014, v. 61, n. 2, p. 119, doi. 10.1507/endocrj.ej13-0431

By:

Yuko Nakagawa;
Yoshiaki Ohtsu;
Masahiro Nagasawa;
Hiroshi Shibata;
Itaru Kojima

Publication type:

Article

Multimodal function of the sweet taste receptor expressed in pancreatic β-cells: generation of diverse patterns of intracellular signals by sweet agonists.

Published in:

Endocrine Journal, 2013, v. 60, n. 10, p. 1191, doi. 10.1507/endocrj.ej13-0282

By:

Yuko Nakagawa;
Masahiro Nagasawa;
Hideo Mogam;
Martin Lohse;
Yuzo Ninomiya;
Itaru Kojima

Publication type:

Article

Involvement of the parasympathetic nervous system in the initiation of regeneration of pancreatic β-cells.

Published in:

Endocrine Journal, 2013, v. 60, n. 5, p. 687, doi. 10.1507/endocrj.ej12-0361

By:

Anya Medina;
Satoko Yamada;
Akemi Hara;
Kohei Hamamoto;
Itaru Kojima

Publication type:

Article

Chemotactic peptide fMetLeuPhe induces translocation of the TRPV2 channel in macrophages.

Published in:

Journal of Cellular Physiology, 2007, v. 210, n. 3, p. 692, doi. 10.1002/jcp.20883

By:

Nagasawa, Masahiro;
Nakagawa, Yuko;
Tanaka, Shigeyasu;
Kojima, Itaru

Publication type:

Article

Attenuation of Bleomycin-induced Pulmonary Fibrosis by Follistatin.

Published in:

American Journal of Respiratory & Critical Care Medicine, 2005, v. 172, n. 6, p. 713, doi. 10.1164/rccm.200412-1620OC

By:

Fumiaki Aoki;
Masahiko Kurabayashi;
Yoshihisa Hasegawa;
Itaru Kojima

Publication type:

Article

Conophylline suppresses hepatic stellate cells and attenuates thioacetamide-induced liver fibrosis in rats.

Published in:

Liver International, 2014, v. 34, n. 7, p. 1057, doi. 10.1111/liv.12328

By:

Kubo, Norio;
Saito, Rie;
Hamano, Kunihisa;
Nagasawa, Masahiro;
Aoki, Fumiaki;
Takei, Izumi;
Umezawa, Kazuo;
Kuwano, Hiroyuki;
Kojima, Itaru

Publication type:

Article

Rat pancreatic islet is formed by unification of multiple endocrine cell clusters.

Published in:

Developmental Dynamics, 2007, v. 236, n. 12, p. 3451, doi. 10.1002/dvdy.21359

By:

Hara, Akemi;
Kadoya, Yuichi;
Kojima, Itaru;
Yamashina, Shohei

Publication type:

Article

Translocation of TRPV2 channel induced by focal administration of mechanical stress.

Published in:

Physiological Reports, 2015, v. 3, n. 2, p. n/a, doi. 10.14814/phy2.12296

By:

Nagasawa, Masahiro;
Kojima, Itaru

Publication type:

Article

Cellular mechanism of hormone action in the kidney: Messenger function of calcium and cyclic AMP.

Published in:

Kidney International, 1986, v. 29, n. 1, p. 90, doi. 10.1038/ki.1986.11

By:

Rasmussen, Howard;
Kojima, Itaru;
Apfeldorf, William;
Barrett, Paula

Publication type:

Article

Electrophysiology of the pancreatic islet β-cell sweet taste receptor TIR3.

Published in:

Pflügers Archiv: European Journal of Physiology, 2019, v. 471, n. 4, p. 647, doi. 10.1007/s00424-018-2237-6

By:

Sanchez-Andres, Juan V.;
Malaisse, Willy J.;
Kojima, Itaru

Publication type:

Article

Correction: T1R3 homomeric sweet taste receptor regulates adipogenesis through Gαs-mediated microtubules disassembly and Rho activation in 3T3-L1 cells.

Published in:

2017

By:

Masubuchi, Yosuke;
Nakagawa, Yuko;
Medina, Johan;
Nagasawa, Masahiro;
Kojima, Itaru;
Rasenick, Mark M.;
Inagaki, Takeshi;
Shibata, Hiroshi

Publication type:

Correction Notice

T1R3 homomeric sweet taste receptor regulates adipogenesis through Gαs-mediated microtubules disassembly and Rho activation in 3T3-L1 cells.

Published in:

PLoS ONE, 2017, v. 12, n. 5, p. 1, doi. 10.1371/journal.pone.0176841

By:

Masubuchi, Yosuke;
Nakagawa, Yuko;
Medina, Johan;
Nagasawa, Masahiro;
Kojima, Itaru;
Rasenick, Mark M.;
Inagaki, Takeshi;
Shibata, Hiroshi

Publication type:

Article

Extracellular matrix modulates insulin production during differentiation of AR42J cells: Functional role of Pax6 transcription factor.

Published in:

Journal of Cellular Biochemistry, 2011, v. 112, n. 1, p. 318, doi. 10.1002/jcb.22930

By:

Hamamoto, Kohei;
Yamada, Satoko;
Hara, Akemi;
Kodera, Tsutomu;
Seno, Masaharu;
Kojima, Itaru

Publication type:

Article

Bimodal role of conventional protein kinase C in insulin secretion from rat pancreaticβ cells.

Published in:

Journal of Physiology, 2004, v. 561, n. 1, p. 133, doi. 10.1113/jphysiol.2004.071241

By:

Zhang, Hui;
Nagasawa, Masahiro;
Yamada, Satoko;
Mogami, Hideo;
Suzuki, Yuko;
Kojima, Itaru

Publication type:

Article

Sweet Taste-Sensing Receptors Expressed in Pancreatic ß-Cells: Sweet Molecules Act as Biased Agonists.

Published in:

Endocrinology & Metabolism, 2014, v. 29, n. 1, p. 12, doi. 10.3803/EnM.2014.29.1.12

By:

Itaru Kojima;
Yuko Nakagawa;
Yoshiaki Ohtsu;
Anya Medina;
Masahiro Nagasawa

Publication type:

Article

Reconfirmation of the anatomy of the left triangular ligament and the appendix fibrosa hepatis in human livers, and its implication in abdominal surgery.

Published in:

Journal of Hepato -- Biliary -- Pancreatic Sciences, 2014, v. 21, n. 12, p. 856, doi. 10.1002/jhbp.144

By:

Kogure, Kimitaka;
Kojima, Itaru;
Kuwano, Hiroyuki;
Matsuzaki, Toshiyuki;
Yorifuji, Hiroshi;
Takata, Kuniaki;
Makuuchi, Masatoshi

Publication type:

Article

Studies on the cell-cycle dependency of the actions of insulin-like growth factor-I in Balb/c 3T3 cells.

Published in:

Journal of Cellular Physiology, 1990, v. 143, n. 3, p. 529, doi. 10.1002/jcp.1041430318

By:

Kojima, Itaru;
Kitaoka, Masafumi;
Ogata, Etsuro

Publication type:

Article

Screening of new bioactive metabolites for diabetes therapy.

Published in:

Internal & Emergency Medicine, 2013, v. 8, p. 57, doi. 10.1007/s11739-013-0922-1

By:

Sidthipong, Kulrawee;
Todo, Satoru;
Takei, Izumi;
Kojima, Itaru;
Umezawa, Kazuo

Publication type:

Article

Elevated mitochondrial biogenesis in skeletal muscle is associated with testosterone-induced body weight loss in male mice.

Published in:

FEBS Letters, 2014, v. 588, n. 10, p. 1935, doi. 10.1016/j.febslet.2014.03.051

By:

Usui, Taro;
Kajita, Kazuo;
Kajita, Toshiko;
Mori, Ichiro;
Hanamoto, Takayuki;
Ikeda, Takahide;
Okada, Hideyuki;
Taguchi, Koichiro;
Kitada, Yoshihiko;
Morita, Hiroyuki;
Sasaki, Tsutomu;
Kitamura, Tadahiro;
Sato, Takashi;
Kojima, Itaru;
Ishizuka, Tatsuo

Publication type:

Article

Roles of CTPL/Sfxn3 and Sfxn family members in pancreatic isletThe nucleotide sequence reported in this article has been deposited in the GenBank database under GenBank accession number AF276997.

Published in:

Journal of Cellular Biochemistry, 2005, v. 95, n. 6, p. 1157, doi. 10.1002/jcb.20481

By:

Yukako Yoshikumi;
Hirosato Mashima;
Namiki Ueda;
Hideki Ohno;
Junko Suzuki;
Shigeyasu Tanaka;
Michio Hayashi;
Nobuo Sekine;
Hirohide Ohnishi;
Hiroshi Yasuda;
Taroh Iiri;
Masao Omata;
Toshiro Fujita;
Itaru Kojima

Publication type:

Article

Processing and juxtacrine activity of membrane-anchored betacellulin.

Published in:

Journal of Cellular Biochemistry, 1999, v. 72, n. 3, p. 423, doi. 10.1002/(SICI)1097-4644(19990301)72:3<423::AID-JCB11>3.0.CO;2-P

By:

Tada, Hiroko;
Sasada, Reiko;
Kawaguchi, Yasuko;
Kojima, Itaru;
Gullick, William J.;
Salomon, David S.;
Igarashi, Koichi;
Seno, Masaharu;
Yamada, Hidenori

Publication type:

Article

Glucose Evokes Rapid Ca<sup>2+</sup> and Cyclic AMP Signals by Activating the Cell-Surface Glucose-Sensing Receptor in Pancreatic β-Cells.

Published in:

PLoS ONE, 2015, v. 10, n. 12, p. 1, doi. 10.1371/journal.pone.0144053

By:

Nakagawa, Yuko;
Nagasawa, Masahiro;
Medina, Johan;
Kojima, Itaru

Publication type:

Article

A Novel Regulatory Function of Sweet Taste-Sensing Receptor in Adipogenic Differentiation of 3T3-L1 Cells.

Published in:

PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0054500

By:

Masubuchi, Yosuke;
Nakagawa, Yuko;
Jinhui Ma;
Sasaki, Tsutomu;
Kitamura, Tadahiro;
Yamamoto, Yoritsuna;
Kurose, Hitoshi;
Kojima, Itaru;
Shibata, Hiroshi

Publication type:

Article

Dicer Is Required for Maintaining Adult Pancreas.

Published in:

PLoS ONE, 2009, v. 4, n. 1, p. 1, doi. 10.1371/journal.pone.0004212

By:

Morita, Sumiyo;
Hara, Akemi;
Kojima, Itaru;
Horii, Takuro;
Kimura, Mika;
Kitamura, Tadahiro;
Ochiya, Takahiro;
Nakanishi, Katsumi;
Matoba, Ryo;
Matsubara, Kenichi;
Hatada, Izuho

Publication type:

Article

Sweet Taste Receptor Serves to Activate Glucose- and Leptin-Responsive Neurons in the Hypothalamic Arcuate Nucleus and Participates in Glucose Responsiveness.

Published in:

Frontiers in Neuroscience, 2016, v. 10, p. 1, doi. 10.3389/fnins.2016.00502

By:

Daisuke Kohno;
Miho Koike;
Yuzo Ninomiya;
Itaru Kojima;
Tadahiro Kitamura;
Toshihiko Yada;
Qingchun Tong;
Xavier Fioramonti;
Dearden, Laura

Publication type:

Article

MCA1 and MCA2 That Mediate Ca<sup>2+</sup> Uptake Have Distinct and Overlapping Roles in Arabidopsis.

Published in:

Plant Physiology, 2010, v. 152, n. 3, p. 1284, doi. 10.1104/pp.109.147371

By:

Yamanaka, Takuya;
Nakagawa, Yuko;
Mori, Kendo;
Nakano, Masataka;
Imamura, Tomomi;
Kataoka, Hajime;
Terashima, Asuka;
lida, Kazuko;
Kojima, Itaru;
Katagiri, Takeshi;
Shinozaki, Kazuo;
Iida, Hidetoshi

Publication type:

Article

Activin A: An autocrine regulator of cell growth and differentiation in renal proximal tubular cells.

Published in:

Kidney International, 2002, v. 62, n. 2, p. 446, doi. 10.1046/j.1523-1755.2002.00463.x

By:

Maeshima, Akito;
Nojima, Yoshihisa;
Kojima, Itaru

Publication type:

Article

Hepatocycle growth factor induces branching tubulogenesis in MDCK cells by modulating the activin-follistatin system.

Published in:

Kidney International, 2000, v. 58, n. 4, p. 1511, doi. 10.1046/j.1523-1755.2000.00313.x

By:

Maeshima, Akito;
You-Qing Zhang;
Furukawa, Megumi;
Naruse, Takuji;
Kojima, Itaru

Publication type:

Article

Dictyostelium differentiation-inducing factor-1 induces glucose transporter 1 translocation and promotes glucose uptake in mammalian cells.

Published in:

FEBS Journal, 2007, v. 274, n. 13, p. 3392, doi. 10.1111/j.1742-4658.2007.05872.x

By:

Omata, Waka;
Shibata, Hiroshi;
Nagasawa, Masahiro;
Kojima, Itaru;
Kikuchi, Haruhisa;
Oshima, Yoshiteru;
Hosaka, Kohei;
Kubohara, Yuzuru

Publication type:

Article

Role of the glucose-sensing receptor in insulin secretion.

Published in:

Diabetes, Obesity & Metabolism, 2017, v. 19, p. 54, doi. 10.1111/dom.13013

By:

Kojima, Itaru;
Medina, Johan;
Nakagawa, Yuko

Publication type:

Article

Triiodothyronine suppresses activin-induced differentiation of erythroleukemia K562 cells under hypoxic conditions.

Published in:

Molecular & Cellular Biochemistry, 2014, v. 391, n. 1/2, p. 217, doi. 10.1007/s11010-014-2005-7

By:

Yamamoto, Yoritsuna;
Shiraishi, Mieno;
Fujita, Masanori;
Kojima, Itaru;
Tanaka, Yuji;
Tachibana, Shoichi

Publication type:

Article

Follistatin, an activin antagonist, ameliorates renal interstitial fibrosis in a rat model of unilateral ureteral obstruction.

Published in:

2014

By:

Maeshima, Akito;
Mishima, Keiichiro;
Yamashita, Shin;
Nakasatomi, Masao;
Miya, Masaaki;
Sakurai, Noriyuki;
Sakairi, Toru;
Ikeuchi, Hidekazu;
Hiromura, Keiju;
Hasegawa, Yoshihisa;
Kojima, Itaru;
Nojima, Yoshihisa

Publication type:

Journal Article

Follistatin, an Activin Antagonist, Ameliorates Renal Interstitial Fibrosis in a Rat Model of Unilateral Ureteral Obstruction.

Published in:

BioMed Research International, 2014, v. 2014, p. 1, doi. 10.1155/2014/376191

By:

Akito Maeshima;
Keiichiro Mishima;
Shin Yamashita;
Masao Nakasatomi;
Masaaki Miya;
Noriyuki Sakurai;
Toru Sakairi;
Hidekazu Ikeuchi;
Keiju Hiromura;
Yoshihisa Hasegawa;
Itaru Kojima;
Yoshihisa Nojima

Publication type:

Article

Therapeutic activity of plant-derived alkaloid conophylline on metabolic syndrome and neurodegenerative disease models.

Published in:

Human Cell, 2018, v. 31, n. 2, p. 95, doi. 10.1007/s13577-017-0196-4

By:

Umezawa, Kazuo;
Kojima, Itaru;
Simizu, Siro;
Lin, Yinzhi;
Fukatsu, Hitomi;
Koide, Naoki;
Nakade, Yukiomi;
Yoneda, Masashi

Publication type:

Article

Transient receptor potential vanilloid 2 activation by focal mechanical stimulation requires interaction with the actin cytoskeleton and enhances growth cone motility.

Published in:

FASEB Journal, 2017, v. 31, n. 4, p. 1368, doi. 10.1096/fj.201600686RR

By:

Shouta Sugio;
Masami Nagasawa;
Itaru Kojima;
Yasuki Ishizaki;
Koji Shibasaki

Publication type:

Article

Regulation of calcium-permeable TRPV2 channel by insulin in pancreatic beta-cells.

Published in:

2009

By:

Hisanaga E;
Nagasawa M;
Ueki K;
Kulkarni RN;
Mori M;
Kojima I;
Hisanaga, Etsuko;
Nagasawa, Masahiro;
Ueki, Kohjiro;
Kulkarni, Rohit N;
Mori, Masatomo;
Kojima, Itaru

Publication type:

journal article

Regulation of Calcium-Permeable TRPV2 Channel by Insulin in Pancreatic β-Cells.

Published in:

Diabetes, 2009, v. 58, n. 1, p. 174, doi. 10.2337/db08-0862

By:

Hisanaga, Etsuko;
Nagasawa, Masahiro;
Ueki, Kohjiro;
Kulkarni, Rohit N.;
Mori, Masatomo;
Kojima, Itaru

Publication type:

Article

The SUMO Conjugating Enzyme Ubc9 is a Regulator of GLUT4 Turnover and Targeting to the Insulin-Responsive Storage Compartment in 3T3-L1 Adipocytes.

Published in:

Diabetes, 2007, v. 56, n. 8, p. 1977, doi. 10.2337/db06-1100

By:

Liu, Li-Bin;
Omata, Waka;
Kojima, Itaru;
Shibata, Hiroshi

Publication type:

Article

Promotion of beta-cell differentiation by conophylline in fetal and neonatal rat pancreas.

Published in:

2004

By:

Ogata, Takeki;
Li, Lei;
Yamada, Satoko;
Yamamoto, Yoritsuna;
Tanaka, Yuji;
Takei, Izumi;
Umezawa, Kazuo;
Kojima, Itaru

Publication type:

journal article

Promotion of β-Cell Differentiation by Conophyllinein Fetal and Neonatal Rat Pancreas.

Published in:

Diabetes, 2004, v. 53, n. 10, p. 2596, doi. 10.2337/diabetes.53.10.2596

By:

Ogata, Takeki;
Li, Lei;
Yamada, Satoko;
Yamamoto, Yoritsuna;
Tanaka, Yuji;
Takei, Izumi;
Umezawa, Kazuo;
Kojima, Itaru

Publication type:

Article

Activin A and betacellulin: effect on regeneration of pancreatic beta-cells in neonatal streptozotocin-treated rats.

Published in:

2004

By:

Li, Lei;
Yi, Zhaohong;
Seno, Masaharu;
Kojima, Itaru

Publication type:

journal article

Activin A and Betacellulin.

Published in:

Diabetes, 2004, v. 53, n. 3, p. 608

By:

Li, Lei;
Yi, Zhaohong;
Seno, Masaharu;
Kojima, Itaru

Publication type:

Article

Role of H1-calponin in pancreatic AR42J cell differentiation into insulin-producing cells.

Published in:

2003

By:

Morioka, Tomoaki;
Koyama, Hidenori;
Yamamura, Hisako;
Tanaka, Shinji;
Fukumoto, Shinya;
Emoto, Masanori;
Mizuguchi, Hiroyuki;
Hayakawa, Takao;
Kojima, Itaru;
Takahashi, Katsuhito;
Nishizawa, Yoshiki

Publication type:

journal article

Combined expression of pancreatic duodenal homeobox 1 and islet factor 1 induces immature enterocytes to produce insulin.

Published in:

2002

By:

Kojima, Hideto;
Nakamura, Takaaki;
Fujita, Yukihiro;
Kishi, Akio;
Fujimiya, Mineko;
Yamada, Syu;
Kudo, Motoi;
Nishio, Yoshihiko;
Maegawa, Hiroshi;
Haneda, Masakazu;
Yasuda, Hitoshi;
Kojima, Itaru;
Seno, Masaharu;
Wong, Norman C.W.;
Kikkawa, Ryuichi;
Kashiwagi, Atsunori

Publication type:

journal article