Works by Ishikawa, Hayato

Results: 57

Oxidative and Enantioselective Cross-Coupling of Aldehydes and Nitromethane Catalyzed by Diphenylprolinol Silyl Ether.

Published in:

Angewandte Chemie, 2011, v. 123, n. 17, p. 4006, doi. 10.1002/ange.201006885

By:

Hayashi, Yujiro;
Itoh, Takahiko;
Ishikawa, Hayato

Publication type:

Article

Asymmetric One-Pot Four-Component Coupling Reaction: Synthesis of Substituted Tetrahydropyrans Catalyzed by Diphenylprolinol Silyl Ether.

Published in:

Angewandte Chemie, 2011, v. 123, n. 16, p. 3858, doi. 10.1002/ange.201005386

By:

Ishikawa, Hayato;
Sawano, Satoshi;
Yasui, Yusuke;
Shibata, Yusuke;
Hayashi, Yujiro

Publication type:

Article

One-Pot Synthesis of Chiral α-Substituted β,γ-Epoxy Aldehyde Derivatives through an Asymmetric Aldol Reaction of Chloroacetaldehyde.

Published in:

Angewandte Chemie, 2011, v. 123, n. 12, p. 2856, doi. 10.1002/ange.201005577

By:

Hayashi, Yujiro;
Yasui, Yusuke;
Kawamura, Tsuyoshi;
Kojima, Masahiro;
Ishikawa, Hayato

Publication type:

Article

Innentitelbild: One-Pot High-Yielding Synthesis of the DPP4-Selective Inhibitor ABT-341 by a Four-Component Coupling Mediated by a Diphenylprolinol Silyl Ether (Angew. Chem. 12/2011).

Published in:

Angewandte Chemie, 2011, v. 123, n. 12, p. 2700, doi. 10.1002/ange.201100625

By:

Ishikawa, Hayato;
Honma, Masakazu;
Hayashi, Yujiro

Publication type:

Article

One-Pot High-Yielding Synthesis of the DPP4-Selective Inhibitor ABT-341 by a Four-Component Coupling Mediated by a Diphenylprolinol Silyl Ether.

Published in:

Angewandte Chemie, 2011, v. 123, n. 12, p. 2876, doi. 10.1002/ange.201006204

By:

Ishikawa, Hayato;
Honma, Masakazu;
Hayashi, Yujiro

Publication type:

Article

High-Yielding Synthesis of the Anti-Influenza Neuramidase Inhibitor (−)-Oseltamivir by Three 'One-Pot' Operations.

Published in:

Angewandte Chemie, 2009, v. 121, n. 7, p. 1330, doi. 10.1002/ange.200804883

By:

Ishikawa, Hayato;
Suzuki, Takaki;
Hayashi, Yujiro

Publication type:

Article

Total Synthesis of (−)- and ent-(+)-Vindorosine: Tandem Intramolecular Diels–Alder/1,3-Dipolar Cycloaddition of 1,3,4-OxadiazolesWe gratefully acknowledge the financial support of the National Institutes of Health (CA42056) and the Skaggs Institute for Chemical Biology.

Published in:

Angewandte Chemie, 2006, v. 118, n. 4, p. 636, doi. 10.1002/ange.200503024

By:

Gregory I. Elliott;
Juraj Velcicky;
Hayato Ishikawa;
YongKai Li;
Dale L. Boger

Publication type:

Article

Organocatalyzed Michael Addition of Aldehydes to Nitro Alkenes - Generally Accepted Mechanism Revisited and Revised.

Published in:

Helvetica Chimica Acta, 2011, v. 94, n. 5, p. 719, doi. 10.1002/hlca.201100122

By:

Patora-Komisarska, Krystyna;
Benohoud, Meryem;
Ishikawa, Hayato;
Seebach, Dieter;
Hayashi, Yujiro

Publication type:

Article

Spontaneous Conversion of 3-Alkyl-substituted 3-Hydroperoxypyrrolidine-2,4-diones into 5-Alkyl-5-hydroxyoxazolidin-4-ones.

Published in:

Chemistry Letters, 2011, v. 40, n. 12, p. 1349, doi. 10.1246/cl.2011.1349

By:

Haque, Md. Aminul;
Hayato Ishikawa;
Hiroshi Nishino

Publication type:

Article

Cover Feature: Indole C5‐Selective Bromination of Indolo[2,3‐a]quinolizidine Alkaloids via In Situ‐Generated Indoline Intermediate (Chem. Eur. J. 35/2024).

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 35, p. 1, doi. 10.1002/chem.202401974

By:

Yoshimura, Go;
Sakamoto, Jukiya;
Kitajima, Mariko;
Ishikawa, Hayato

Publication type:

Article

Indole C5‐Selective Bromination of Indolo[2,3‐a]quinolizidine Alkaloids via In Situ‐Generated Indoline Intermediate.

Published in:

Chemistry - A European Journal, 2024, v. 30, n. 35, p. 1, doi. 10.1002/chem.202401153

By:

Yoshimura, Go;
Sakamoto, Jukiya;
Kitajima, Mariko;
Ishikawa, Hayato

Publication type:

Article

Cover Feature: Total Syntheses of (+)‐Villocarine A, (−)‐Apogeissoschizine, and (+)‐Geissoschizine (Chem. Eur. J. 18/2023).

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 18, p. 1, doi. 10.1002/chem.202300534

By:

Sakamoto, Jukiya;
Kitajima, Mariko;
Ishikawa, Hayato

Publication type:

Article

Total Syntheses of (+)‐Villocarine A, (−)‐Apogeissoschizine, and (+)‐Geissoschizine.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 18, p. 1, doi. 10.1002/chem.202300179

By:

Sakamoto, Jukiya;
Kitajima, Mariko;
Ishikawa, Hayato

Publication type:

Article

Cover Feature: Bioinspired Transformations Using Strictosidine Aglycones: Divergent Total Syntheses of Monoterpenoid Indole Alkaloids in the Early Stage of Biosynthesis (Chem. Eur. J. 10/2022).

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 11, p. 1, doi. 10.1002/chem.202200315

By:

Sakamoto, Jukiya;
Ishikawa, Hayato

Publication type:

Article

Bioinspired Transformations Using Strictosidine Aglycones: Divergent Total Syntheses of Monoterpenoid Indole Alkaloids in the Early Stage of Biosynthesis.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 11, p. 1, doi. 10.1002/chem.202104052

By:

Sakamoto, Jukiya;
Ishikawa, Hayato

Publication type:

Article

Total Syntheses of (−)‐Strictosidine and Related Indole Alkaloid Glycosides.

Published in:

Angewandte Chemie, 2020, v. 132, n. 32, p. 13516, doi. 10.1002/ange.202005748

By:

Sakamoto, Jukiya;
Umeda, Yuhei;
Rakumitsu, Kenta;
Sumimoto, Michinori;
Ishikawa, Hayato

Publication type:

Article

Constituents of Uncaria lanosa f. philippinensis and their anti-amyloidogenic activity.

Published in:

Natural Product Research, 2025, v. 39, n. 5, p. 1406, doi. 10.1080/14786419.2023.2294481

By:

Tan, Mario A.;
Ishikawa, Hayato

Publication type:

Article

Modified Bohlmann–Rahtz Pyridine Synthesis for Cyclic Ketones.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 22, p. 1, doi. 10.1002/chem.202500298

By:

Ikeno, Keita;
Oku, Haruna;
Rakumitsu, Kenta;
Kitajima, Mariko;
Ishikawa, Hayato

Publication type:

Article

Bioinspired Total Synthesis and Structural Reidentification of Alstrostines.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 18, p. 1, doi. 10.1002/chem.202500069

By:

Hiruma, Daiki;
Yoshidome, Akiho;
Rakumitsu, Kenta;
Kitajima, Mariko;
Hitora, Yuki;
Tsukamoto, Sachiko;
Schinnerl, Johann;
Brecker, Lothar;
Ishikawa, Hayato

Publication type:

Article

Oxidative and Enantioselective Cross-Coupling of Aldehydes and Nitromethane Catalyzed by Diphenylprolinol Silyl Ether.

Published in:

Angewandte Chemie International Edition, 2011, v. 50, n. 17, p. 3920, doi. 10.1002/anie.201006885

By:

Hayashi, Yujiro;
Itoh, Takahiko;
Ishikawa, Hayato

Publication type:

Article

Asymmetric One-Pot Four-Component Coupling Reaction: Synthesis of Substituted Tetrahydropyrans Catalyzed by Diphenylprolinol Silyl Ether.

Published in:

Angewandte Chemie International Edition, 2011, v. 50, n. 16, p. 3774, doi. 10.1002/anie.201005386

By:

Ishikawa, Hayato;
Sawano, Satoshi;
Yasui, Yusuke;
Shibata, Yusuke;
Hayashi, Yujiro

Publication type:

Article

Inside Cover: One-Pot High-Yielding Synthesis of the DPP4-Selective Inhibitor ABT-341 by a Four-Component Coupling Mediated by a Diphenylprolinol Silyl Ether (Angew. Chem. Int. Ed. 12/2011).

Published in:

Angewandte Chemie International Edition, 2011, v. 50, n. 12, p. 2650, doi. 10.1002/anie.201100625

By:

Ishikawa, Hayato;
Honma, Masakazu;
Hayashi, Yujiro

Publication type:

Article

One-Pot High-Yielding Synthesis of the DPP4-Selective Inhibitor ABT-341 by a Four-Component Coupling Mediated by a Diphenylprolinol Silyl Ether.

Published in:

Angewandte Chemie International Edition, 2011, v. 50, n. 12, p. 2824, doi. 10.1002/anie.201006204

By:

Ishikawa, Hayato;
Honma, Masakazu;
Hayashi, Yujiro

Publication type:

Article

One-Pot Synthesis of Chiral α-Substituted β,γ-Epoxy Aldehyde Derivatives through an Asymmetric Aldol Reaction of Chloroacetaldehyde.

Published in:

Angewandte Chemie International Edition, 2011, v. 50, n. 12, p. 2804, doi. 10.1002/anie.201005577

By:

Hayashi, Yujiro;
Yasui, Yusuke;
Kawamura, Tsuyoshi;
Kojima, Masahiro;
Ishikawa, Hayato

Publication type:

Article

High-Yielding Synthesis of the Anti-Influenza Neuramidase Inhibitor (−)-Oseltamivir by Three 'One-Pot' Operations.

Published in:

Angewandte Chemie International Edition, 2009, v. 48, n. 7, p. 1304, doi. 10.1002/anie.200804883

By:

Ishikawa, Hayato;
Suzuki, Takaki;
Hayashi, Yujiro

Publication type:

Article

Direct Organocatalytic Mannich Reaction of Acetaldehyde: An Improved Catalyst and Mechanistic Insight from a Computational Study.

Published in:

Angewandte Chemie International Edition, 2008, v. 47, n. 47, p. 9053, doi. 10.1002/anie.200802073

By:

Hayashi, Yujiro;
Okano, Tsubasa;
Itoh, Takahiko;
Urushima, Tatsuya;
Ishikawa, Hayato;
Uchimaru, Tadafumi

Publication type:

Article

The Asymmetric Total Synthesis of (+)-Cytotrienin A, an Ansamycin-Type Anticancer Drug.

Published in:

Angewandte Chemie International Edition, 2008, v. 47, n. 35, p. 6657, doi. 10.1002/anie.200802079

By:

Hayashi, Yujiro;
Shoji, Mitsuru;
Ishikawa, Hayato;
Yamaguchi, Junichiro;
Tamura, Tomohiro;
Imai, Hiroki;
Nishigaya, Yosuke;
Takabe, Kenichi;
Kakeya, Hideaki;
Osada, Hiroyuki

Publication type:

Article

Asymmetric Diels-Alder Reactions of α,β-Unsaturated Aldehydes Catalyzed by a Diarylprolinol Silyl Ether Salt in the Presence of Water.

Published in:

Angewandte Chemie International Edition, 2008, v. 47, n. 35, p. 6634, doi. 10.1002/anie.200801408

By:

Hayashi, Yujiro;
Samanta, Sampak;
Gotoh, Hiroaki;
Ishikawa, Hayato

Publication type:

Article

Asymmetric Michael Reaction of Acetaldehyde Catalyzed by Diphenylprolinol Silyl Ether.

Published in:

Angewandte Chemie International Edition, 2008, v. 47, n. 25, p. 4722, doi. 10.1002/anie.200801130

By:

Hayashi, Yujiro;
Itoh, Takahiko;
Ohkubo, Masahiro;
Ishikawa, Hayato

Publication type:

Article

Diphenylprolinol Silyl Ether as a Catalyst in an Enantioselective, Catalytic, Formal Aza [3+3] Cycloaddition Reaction for the Formation of Enantioenriched Piperidines.

Published in:

Angewandte Chemie International Edition, 2008, v. 47, n. 21, p. 4012, doi. 10.1002/anie.200800662

By:

Hayashi, Yujiro;
Gotoh, Hiroaki;
Masui, Ryouhei;
Ishikawa, Hayato

Publication type:

Article

A Diarylprolinol in an Asymmetric, Catalytic, and Direct Crossed-Aldol Reaction of Acetaldehyde.

Published in:

Angewandte Chemie International Edition, 2008, v. 47, n. 11, p. 2082, doi. 10.1002/anie.200704870

By:

Hayashi, Yujiro;
Itoh, Takahiko;
Aratake, Seiji;
Ishikawa, Hayato

Publication type:

Article

Moss Chloroplasts Are Surrounded by a Peptidoglycan Wall Containing D-Amino Acids.

Published in:

Plant Cell, 2016, v. 28, n. 7, p. 1521, doi. 10.1105/tpc.16.00104

By:

Hirano, Takayuki;
Tanidokoro, Koji;
Shimizu, Yasuhiro;
Kawarabayasi, Yutaka;
Ohshima, Toshihisa;
Sato, Momo;
Tadano, Shinji;
Ishikawa, Hayato;
Takio, Susumu;
Takechi, Katsuaki;
Takano, Hiroyoshi

Publication type:

Article

Synthesis of (-)-Oseltamivir by Using a Microreactor in the Curtius Rearrangement.

Published in:

European Journal of Organic Chemistry, 2011, v. 2011, n. 30, p. 6020, doi. 10.1002/ejoc.201100074

By:

Ishikawa, Hayato;
Bondzic, Bojan P.;
Hayashi, Yujiro

Publication type:

Article

Total Syntheses of (−)‐Strictosidine and Related Indole Alkaloid Glycosides.

Published in:

Angewandte Chemie International Edition, 2020, v. 59, n. 32, p. 13414, doi. 10.1002/anie.202005748

By:

Sakamoto, Jukiya;
Umeda, Yuhei;
Rakumitsu, Kenta;
Sumimoto, Michinori;
Ishikawa, Hayato

Publication type:

Article

Total Syntheses of (−)‐Secologanin, (−)‐5‐Carboxystrictosidine, and (−)‐Rubenine.

Published in:

Chemistry - A European Journal, 2019, v. 25, n. 38, p. 8996, doi. 10.1002/chem.201902073

By:

Rakumitsu, Kenta;
Sakamoto, Jukiya;
Ishikawa, Hayato

Publication type:

Article

Reduction of laser speckle noise by using particle-dispersed liquid crystals.

Published in:

Molecular Crystals & Liquid Crystals, 2017, v. 646, n. 1, p. 93, doi. 10.1080/15421406.2017.1284540

By:

Ishikawa, Hayato;
Shibase, Atsushi;
Weng, Wu;
Ono, Masatoshi;
Furue, Hirokazu

Publication type:

Article

Rhamnogalacturonan-I as a nematode chemoattractant from Lotus corniculatus L. super-growing root culture.

Published in:

Frontiers in Plant Science, 2023, v. 14, p. 1, doi. 10.3389/fpls.2022.1008725

By:

Morihiro Oota;
Syuuto Toyoda;
Toshihisa Kotake;
Naoki Wada;
Masatsugu Hashiguchi;
Ryo Akashi;
Hayato Ishikawa;
Favery, Bruno;
Tsai, Allen Yi-Lun;
Shinichiro Sawa

Publication type:

Article

Pandanus amaryllifolius Exhibits In Vitro Anti-Amyloidogenic Activity and Promotes Neuroprotective Effects in Amyloid-β-Induced SH-SY5Y Cells.

Published in:

Nutrients, 2022, v. 14, n. 19, p. 3962, doi. 10.3390/nu14193962

By:

Tan, Mario A.;
Ishikawa, Hayato;
An, Seong Soo A.

Publication type:

Article

Total Synthesis of (−)- and ent-(+)-Vindorosine: Tandem Intramolecular Diels–Alder/1,3-Dipolar Cycloaddition of 1,3,4-OxadiazolesWe gratefully acknowledge the financial support of the National Institutes of Health (CA42056) and the Skaggs Institute for Chemical Biology.

Published in:

Angewandte Chemie International Edition, 2006, v. 45, n. 4, p. 620, doi. 10.1002/anie.200503024

By:

Gregory I. Elliott;
Juraj Velcicky;
Hayato Ishikawa;
YongKai Li;
Dale L. Boger

Publication type:

Article

Collective Synthesis and Biological Evaluation of Tryptophan-Based Dimeric Diketopiperazine Alkaloids.

Published in:

Chemistry - A European Journal, 2016, v. 22, n. 4, p. 1277, doi. 10.1002/chem.201503417

By:

Tadano, Shinji;
Sugimachi, Yukihiro;
Sumimoto, Michinori;
Tsukamoto, Sachiko;
Ishikawa, Hayato

Publication type:

Article

Inside Cover: Collective Synthesis and Biological Evaluation of Tryptophan-Based Dimeric Diketopiperazine Alkaloids (Chem. Eur. J. 4/2016).

Published in:

Chemistry - A European Journal, 2016, v. 22, n. 4, p. 1182, doi. 10.1002/chem.201504560

By:

Tadano, Shinji;
Sugimachi, Yukihiro;
Sumimoto, Michinori;
Tsukamoto, Sachiko;
Ishikawa, Hayato

Publication type:

Article

Efficient Organocatalytic Construction of C4-Alkyl Substituted Piperidines and Their Application to the Synthesis of (+)-α-Skytanthine.

Published in:

Chemistry - A European Journal, 2015, v. 21, n. 42, p. 14758, doi. 10.1002/chem.201503117

By:

Shiomi, Shinya;
Sugahara, Erika;
Ishikawa, Hayato

Publication type:

Article

One-Pot Synthesis of (−)-Oseltamivir and Mechanistic Insights into the Organocatalyzed Michael Reaction.

Published in:

Chemistry - A European Journal, 2013, v. 19, n. 52, p. 17789, doi. 10.1002/chem.201302371

By:

Mukaiyama , Takasuke;
Ishikawa , Hayato;
Koshino, Hiroyuki;
Hayashi , Yujiro

Publication type:

Article

Corrigendum: High-Yielding Synthesis of the Anti-Influenza Neuraminidase Inhibitor (−)-Oseltamivir by Two 'One-Pot' Sequences.

Published in:

Chemistry - A European Journal, 2011, v. 17, n. 44, p. 12227, doi. 10.1002/chem.201190224

By:

Ishikawa, Hayato;
Suzuki, Takaki;
Orita, Hideo;
Uchimaru, Tadafumi;
Hayashi, Yujiro

Publication type:

Article

One-Pot Synthesis of Chiral Aziridines by a Domino Reaction by Using Desulfonylative Formation on the N-Tosyl Imine of Chloroacetaldehyde with an Asymmetric Mannich Reaction as a Key Step.

Published in:

Chemistry - A European Journal, 2011, v. 17, n. 42, p. 11715, doi. 10.1002/chem.201101668

By:

Hayashi, Yujiro;
Urushima, Tatsuya;
Sakamoto, Daisuke;
Torii, Kou;
Ishikawa, Hayato

Publication type:

Article

Asymmetric Mannich Reaction of Imines Derived from Aliphatic and Aromatic Aldehydes Catalyzed by Diarylprolinol Silyl Ether.

Published in:

Chemistry - A European Journal, 2011, v. 17, n. 30, p. 8273, doi. 10.1002/chem.201101077

By:

Urushima, Tatsuya;
Ishikawa, Hayato;
Hayashi, Yujiro

Publication type:

Article

Redox Switching of Orthoquinone-Containing Aromatic Compounds with Hydrogen and Oxygen Gas.

Published in:

Angewandte Chemie, 2016, v. 128, n. 26, p. 7558, doi. 10.1002/ange.201601906

By:

Urakawa, Kazuki;
Sumimoto, Michinori;
Arisawa, Mitsuhiro;
Matsuda, Masaki;
Ishikawa, Hayato

Publication type:

Article

Bio-Inspired Dimerization Reaction of Tryptophan Derivatives in Aqueous Acidic Media: Three-Step Syntheses of (+)-WIN 64821, (−)-Ditryptophenaline, and (+)-Naseseazine B.

Published in:

Angewandte Chemie, 2013, v. 125, n. 31, p. 8148, doi. 10.1002/ange.201303143

By:

Tadano, Shinji;
Mukaeda, Yuri;
Ishikawa, Hayato

Publication type:

Article

Diphenylprolinol Silyl Ether as a Catalyst in an Enantioselective, Catalytic Michael Reaction for the Formation of α,α-Disubstituted α-Amino Acid Derivatives.

Published in:

Chemistry - An Asian Journal, 2009, v. 4, n. 2, p. 246, doi. 10.1002/asia.200800394

By:

Hayashi, Yujiro;
Obi, Kazuki;
Ohta, Yusuke;
Okamura, Daichi;
Ishikawa, Hayato

Publication type:

Article

New lupan-type triterpenoids.

Published in:

Zeitschrift für Naturforschung. Section C: A Journal of Biosciences, 2016, v. 71, n. 11/12, p. 381, doi. 10.1515/znc-2015-0235

By:

Mkounga, Pierre;
Maza, Hermine L.D.;
Ouahouo, Blandine M.W.;
Tyon, Lydie N.;
Ishikawa, Hayato;
Nishino, Hiroshi;
Nkengfack, Augustin E.

Publication type:

Article