Works by Ishihara, Tomohiko

Results: 29

Dentatorubropallidoluysian Atrophy with Prominent Autonomic Dysfunction.

Published in:

Internal Medicine, 2023, v. 62, n. 6, p. 889, doi. 10.2169/internalmedicine.9616-22

By:

Ayako Shioya;
Hiroshi Takuma;
Norio Ohkoshi;
Kuniyoshi Hirano;
Tomohiko Ishihara;
Kazuhiro Ishii;
Akira Tamaoka

Publication type:

Article

TDP-43 differentially propagates to induce antero- and retrograde degeneration in the corticospinal circuits in mouse focal ALS models.

Published in:

Acta Neuropathologica, 2023, v. 146, n. 4, p. 611, doi. 10.1007/s00401-023-02615-8

By:

Tsuboguchi, Shintaro;
Nakamura, Yuka;
Ishihara, Tomohiko;
Kato, Taisuke;
Sato, Tokiharu;
Koyama, Akihide;
Mori, Hideki;
Koike, Yuka;
Onodera, Osamu;
Ueno, Masaki

Publication type:

Article

Relapse of multiple sclerosis in a patient retaining CCR7-expressing T cells in CSF under fingolimod therapy.

Published in:

Multiple Sclerosis Journal, 2013, v. 19, n. 9, p. 1230, doi. 10.1177/1352458513481395

By:

Yokoseki, Akiko;
Saji, Etsuji;
Arakawa, Musashi;
Hokari, Mariko;
Ishiguro, Takanobu;
Yanagimura, Fumihiro;
Ishihara, Tomohiko;
Okamoto, Kouichirou;
Nishizawa, Masatoyo;
Kawachi, Izumi

Publication type:

Article

Slow disease progression and characteristic TDP‐43 inclusions in a patient with familial amyotrophic lateral sclerosis carrying a TARDBP G357S variant.

Published in:

Neuropathology & Applied Neurobiology, 2024, v. 50, n. 1, p. 1, doi. 10.1111/nan.12966

By:

Sainouchi, Makoto;
Oginezawa, Shinya;
Tada, Mari;
Ishihara, Tomohiko;
Onodera, Osamu;
Kakita, Akiyoshi

Publication type:

Article

Reliability study for the Japanese version of the Columbia Muscle Cramp Scale in amyotrophic lateral sclerosis.

Published in:

Neurology & Clinical Neuroscience, 2025, v. 13, n. 1, p. 14, doi. 10.1111/ncn3.12838

By:

Sawada, Masahiro;
Hirayama, Takehisa;
Yanagihashi, Masaru;
Fukushima, Koji;
Izumi, Yuishin;
Naoi, Tameto;
Morita, Mitsuya;
Warita, Hitoshi;
Aoki, Masashi;
Iguchi, Yohei;
Katsuno, Masahisa;
Ogawa, Nobuhiro;
Urusitani, Makoto;
Ishihara, Tomohiko;
Onodera, Osamu;
Murakami, Yoshitaka;
Mitsumoto, Hiroshi;
Kano, Osamu

Publication type:

Article

The Japan MSA registry: A multicenter cohort study of multiple system atrophy.

Published in:

Neurology & Clinical Neuroscience, 2024, v. 12, n. 5, p. 271, doi. 10.1111/ncn3.12809

By:

Chikada, Ayaka;
Orimo, Kenta;
Mitsui, Jun;
Matsukawa, Takashi;
Ishiura, Hiroyuki;
Toda, Tatsushi;
Mizusawa, Hidehiro;
Takahashi, Yuji;
Katsuno, Masahisa;
Hara, Kazuhiro;
Onodera, Osamu;
Ishihara, Tomohiko;
Tada, Masayoshi;
Kuwabara, Satoshi;
Sugiyama, Atsuhiko;
Yamanaka, Yoshitaka;
Takahashi, Ryosuke;
Sawamoto, Nobukatsu;
Sakato, Yusuke;
Ishimoto, Tomoyuki

Publication type:

Article

Genotype–phenotype correlations in early onset ataxia with ocular motor apraxia and hypoalbuminaemia.

Published in:

Brain: A Journal of Neurology, 2011, v. 134, n. 5, p. 1387, doi. 10.1093/brain/awr069

By:

Yokoseki, Akio;
Ishihara, Tomohiko;
Koyama, Akihide;
Shiga, Atsushi;
Yamada, Mitsunori;
Suzuki, Chieko;
Sekijima, Yoshiki;
Maruta, Kyoko;
Tsuchiya, Miyuki;
Date, Hidetoshi;
Sato, Tatsuya;
Tada, Masayoshi;
Ikeuchi, Takeshi;
Tsuji, Shoji;
Nishizawa, Masatoyo;
Onodera, Osamu

Publication type:

Article

Depression and psychiatric symptoms preceding onset of dementia in a family with early-onset Alzheimer disease with a novel PSEN1 mutation.

Published in:

2009

By:

Kasuga, Kensaku;
Ohno, Tsukasa;
Ishihara, Tomohiko;
Miyashita, Akinori;
Kuwano, Ryozo;
Onodera, Osamu;
Nishizawa, Masatoyo;
Ikeuchi, Takeshi

Publication type:

Letter

Sleep apnea associated with floppy epiglottis in adult-onset Alexander disease: A case report.

Published in:

Movement Disorders, 2010, v. 25, n. 8, p. 1098, doi. 10.1002/mds.23042

By:

Ishikawa, Masanori;
Shimohata, Takayoshi;
Ishihara, Tomohiko;
Nakayama, Hideaki;
Tomita, Masahiko;
Nishizawa, Masatoyo

Publication type:

Article

Atypical Parkinsonism in distal myopathy with rimmed vacuoles.

Published in:

Movement Disorders, 2008, v. 23, n. 6, p. 912, doi. 10.1002/mds.22018

By:

Ishihara, Tomohiko;
Ozawa, Tetsutaro;
Igarashi, Shuichi;
Kitsukawa, Yuko;
Takagi, Masahito;
Hirose, Masaki;
Tokutake, Takayoshi;
Tanaka, Keiko;
Nishizawa, Masatoyo

Publication type:

Article

SMN2 gene copy number affects the incidence and prognosis of motor neuron diseases in Japan.

Published in:

BMC Medical Genomics, 2024, v. 17, n. 1, p. 1, doi. 10.1186/s12920-024-02026-y

By:

Ishihara, Tomohiko;
Koyama, Akihide;
Atsuta, Naoki;
Tada, Mari;
Toyoda, Saori;
Kashiwagi, Kenta;
Hirokawa, Sachiko;
Hatano, Yuya;
Yokoseki, Akio;
Nakamura, Ryoichi;
Tohnai, Genki;
Izumi, Yuishin;
Kaji, Ryuji;
Morita, Mitsuya;
Tamura, Asako;
Kano, Osamu;
Aoki, Masashi;
Kuwabara, Satoshi;
Kakita, Akiyoshi;
Sobue, Gen

Publication type:

Article

Robustness and Vulnerability of the Autoregulatory System That Maintains Nuclear TDP-43 Levels: A Trade-off Hypothesis for ALS Pathology Based on in Silico Data.

Published in:

Frontiers in Neuroscience, 2018, p. 1, doi. 10.3389/fnins.2018.00028

By:

Sugai, Akihiro;
Kato, Taisuke;
Koyama, Akihide;
Koike, Yuka;
Kasahara, Sou;
Konno, Takuya;
Ishihara, Tomohiko;
Onodera, Osamu

Publication type:

Article

Accuracy of a machine learning method based on structural and locational information from AlphaFold2 for predicting the pathogenicity of TARDBP and FUS gene variants in ALS.

Published in:

BMC Bioinformatics, 2023, v. 24, n. 1, p. 1, doi. 10.1186/s12859-023-05338-5

By:

Hatano, Yuya;
Ishihara, Tomohiko;
Onodera, Osamu

Publication type:

Article

Sporadic four-repeat tauopathy with frontotemporal lobar degeneration, Parkinsonism, and motor neuron disease: a distinct clinicopathological and biochemical disease entity.

Published in:

Acta Neuropathologica, 2010, v. 120, n. 1, p. 21, doi. 10.1007/s00401-010-0649-2

By:

Yong-Juan Fu;
Nishihira, Yasushi;
Kuroda, Shigetoshi;
Toyoshima, Yasuko;
Ishihara, Tomohiko;
Shinozaki, Makoto;
Miyashita, Akinori;
Yue-Shan Piao;
Chun-Feng Tan;
Tani, Takashi;
Koike, Ryoko;
Iwanaga, Keisuke;
Tsujihata, Mitsuhiro;
Onodera, Osamu;
Kuwano, Ryozo;
Nishizawa, Masatoyo;
Kakita, Akiyoshi;
Ikeuchi, Takeshi;
Takahashi, Hitoshi

Publication type:

Article

A new Japanese amyotrophic lateral sclerosis family with TARDBP (TDP‐43) mutation.

Published in:

Neurology & Clinical Neuroscience, 2019, v. 7, n. 2, p. 101, doi. 10.1111/ncn3.12250

By:

Hara, Kenju;
Ishihara, Tomohiko;
Onodera, Osamu;
Ishiguro, Hideaki

Publication type:

Article

Inappropriate interpretation of non‐pathogenic HTRA1 variant as pathogenic.

Published in:

Annals of Clinical & Translational Neurology, 2023, v. 10, n. 7, p. 1261, doi. 10.1002/acn3.51817

By:

Uemura, Masahiro;
Kitahara, Sho;
Kato, Taisuke;
Nozaki, Hiroaki;
Ando, Shoichiro;
Ishihara, Tomohiko;
Onodera, Osamu

Publication type:

Article

Correction to: A novel splicing variant of ANXA11 in a patient with amyotrophic lateral sclerosis: histologic and biochemical features.

Published in:

2021

By:

Sainouchi, Makoto;
Hatano, Yuya;
Tada, Mari;
Ishihara, Tomohiko;
Ando, Shoichiro;
Kato, Taisuke;
Tokunaga, Jun;
Ito, Gaku;
Miyahara, Hiroaki;
Toyoshima, Yasuko;
Yokoseki, Akio;
Ozawa, Tetsutaro;
Akazawa, Kohei;
Onodera, Osamu;
Kakita, Akiyoshi

Publication type:

Correction Notice

A novel splicing variant of ANXA11 in a patient with amyotrophic lateral sclerosis: histologic and biochemical features.

Published in:

2021

By:

Sainouchi, Makoto;
Hatano, Yuya;
Tada, Mari;
Ishihara, Tomohiko;
Ando, Shoichiro;
Kato, Taisuke;
Tokunaga, Jun;
Ito, Gaku;
Miyahara, Hiroaki;
Toyoshima, Yasuko;
Yokoseki, Akio;
Ozawa, Tetsutaro;
Akazawa, Kohei;
Onodera, Osamu;
Kakita, Akiyoshi

Publication type:

Letter

A novel splicing variant of ANXA11 in a patient with amyotrophic lateral sclerosis: histologic and biochemical features.

Published in:

2021

By:

Sainouchi, Makoto;
Hatano, Yuya;
Tada, Mari;
Ishihara, Tomohiko;
Ando, Shoichiro;
Kato, Taisuke;
Tokunaga, Jun;
Ito, Gaku;
Miyahara, Hiroaki;
Toyoshima, Yasuko;
Yokoseki, Akio;
Ozawa, Tetsutaro;
Akazawa, Kohei;
Onodera, Osamu;
Kakita, Akiyoshi

Publication type:

Letter

Case Report: A patient with spinocerebellar ataxia type 31 and sporadic Creutzfeldt-Jakob disease.

Published in:

Prion, 2018, v. 12, n. 2, p. 147, doi. 10.1080/19336896.2018.1436926

By:

Saito, Natsumi;
Ishihara, Tomohiko;
Kasuga, Kensaku;
Nishida, Mana;
Ishiguro, Takanobu;
Nozaki, Hiroaki;
Shimohata, Takayoshi;
Onodera, Osamu;
Nishizawa, Masatoyo

Publication type:

Article

Minor splicing pathway is not minor any more: Implications for the pathogenesis of motor neuron diseases.

Published in:

Neuropathology, 2014, v. 34, n. 1, p. 99, doi. 10.1111/neup.12070

By:

Onodera, Osamu;
Ishihara, Tomohiko;
Shiga, Atsushi;
Ariizumi, Yuko;
Yokoseki, Akio;
Nishizawa, Masatoyo

Publication type:

Article

Increased cytoplasmic TARDBP mRNA in affected spinal motor neurons in ALS caused by abnormal autoregulation of TDP-43.

Published in:

Nucleic Acids Research, 2016, v. 44, n. 12, p. 5820, doi. 10.1093/nar/gkw499

By:

Akihide Koyama;
Akihiro Sugai;
Taisuke Kato;
Tomohiko Ishihara;
Atsushi Shiga;
Yasuko Toyoshima;
Misaki Koyama;
Takuya Konno;
Sachiko Hirokawa;
Akio Yokoseki;
Masatoyo Nishizawa;
Akiyoshi Kakita;
Hitoshi Takahashi;
Osamu Onodera

Publication type:

Article

Phosphorylated TDP-43 aggregates in skeletal and cardiac muscle are a marker of myogenic degeneration in amyotrophic lateral sclerosis and various conditions.

Published in:

Acta Neuropathologica Communications, 2019, v. 7, n. 1, p. N.PAG, doi. 10.1186/s40478-019-0824-1

By:

Mori, Fumiaki;
Tada, Mari;
Kon, Tomoya;
Miki, Yasuo;
Tanji, Kunikazu;
Kurotaki, Hidekachi;
Tomiyama, Masahiko;
Ishihara, Tomohiko;
Onodera, Osamu;
Kakita, Akiyoshi;
Wakabayashi, Koichi

Publication type:

Article

Decreased number of Gemini of coiled bodies and U12 snRNA level in amyotrophic lateral sclerosis.

Published in:

Human Molecular Genetics, 2013, v. 22, n. 20, p. 4136, doi. 10.1093/hmg/ddt262

By:

Ishihara, Tomohiko;
Ariizumi, Yuko;
Shiga, Atsushi;
Kato, Taisuke;
Tan, Chun-Feng;
Sato, Tatsuya;
Miki, Yukari;
Yokoo, Mariko;
Fujino, Takeshi;
Koyama, Akihide;
Yokoseki, Akio;
Nishizawa, Masatoyo;
Kakita, Akiyoshi;
Takahashi, Hitoshi;
Onodera, Osamu

Publication type:

Article

Alteration of POLDIP3 Splicing Associated with Loss of Function of TDP-43 in Tissues Affected with ALS.

Published in:

PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0043120

By:

Shiga, Atsushi;
Ishihara, Tomohiko;
Miyashita, Akinori;
Kuwabara, Misaki;
Kato, Taisuke;
Watanabe, Norihiro;
Yamahira, Akie;
Kondo, Chigusa;
Yokoseki, Akio;
Takahashi, Masuhiro;
Kuwano, Ryozo;
Kakita, Akiyoshi;
Nishizawa, Masatoyo;
Takahashi, Hitoshi;
Onodera, Osamu;
Nagai, Yoshitaka

Publication type:

Article

Preclinical Characterization of the Tau PET Tracer [ <sup>18</sup>F]SNFT-1: Comparison of Tau PET Tracers.

Published in:

Journal of Nuclear Medicine, 2023, v. 64, n. 9, p. 1495, doi. 10.2967/jnumed.123.265593

By:

Ryuichi Harada;
Pradith Lerdsirisuk;
Yuki Shimizu;
Yuka Yokoyama;
Yiqing Du;
Kaede Kudo;
Michinori Ezura;
Yoichi Ishikawa;
Ren Iwata;
Miho Shidahara;
Aiko Ishiki;
Akio Kikuchi;
Yuya Hatano;
Tomohiko Ishihara;
Osamu Onodera;
Yasushi Iwasaki;
Mari Yoshida;
Yasuyuki Taki;
Hiroyuki Arai;
Yukitsuka Kudo

Publication type:

Article

Folic acid inhibits 5‐methyltetrahydrofolate transport across the blood–cerebrospinal fluid barrier: Clinical biochemical data from two cases.

Published in:

2022

By:

Akiyama, Tomoyuki;
Kuki, Ichiro;
Kim, Kiyohiro;
Yamamoto, Naohiro;
Yamada, Yumi;
Igarashi, Kazuya;
Ishihara, Tomohiko;
Hatano, Yuya;
Kobayashi, Katsuhiro

Publication type:

Case Study

Age-related demethylation of the TDP-43 autoregulatory region in the human motor cortex.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02621-0

By:

Koike, Yuka;
Sugai, Akihiro;
Hara, Norikazu;
Ito, Junko;
Yokoseki, Akio;
Ishihara, Tomohiko;
Yamagishi, Takuma;
Tsuboguchi, Shintaro;
Tada, Mari;
Ikeuchi, Takeshi;
Kakita, Akiyoshi;
Onodera, Osamu

Publication type:

Article

The analysis of schizophrenia-like psychosis in dentatorubral-pallidoluysian atrophy.

Published in:

Frontiers in Neurology, 2025, p. 1, doi. 10.3389/fneur.2025.1564856

By:

Ikegami, Ichiko;
Mitsuhashi Koike, Yuka;
Hayashi, Hideki;
Hirokawa, Sachiko;
Ando, Shoichiro;
Ishihara, Tomohiko;
Onodera, Osamu

Publication type:

Article