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Comparison of tofogliflozin versus glimepiride as the third oral agent added to metformin plus a dipeptidyl peptidase‐4 inhibitor in Japanese patients with type 2 diabetes: A randomized, 24‐week, open‐label, controlled trial (STOP‐OB)
- Published in:
- Diabetes, Obesity & Metabolism, 2020, v. 22, n. 9, p. 1659, doi. 10.1111/dom.14059
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- Publication type:
- Article
Efficacy and safety of ipragliflozin as add-on therapy to insulin in Japanese patients with type 2 diabetes mellitus ( IOLITE): a multi-centre, randomized, placebo-controlled, double-blind study.
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- Diabetes, Obesity & Metabolism, 2016, v. 18, n. 12, p. 1207, doi. 10.1111/dom.12745
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- Publication type:
- Article
Efficacy and Safety of Switching from Sitagliptin to Ipragliflozin in Obese Japanese Patients with Type 2 Diabetes Mellitus: A Single-Arm Multicenter Interventional Study.
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- Clinical Drug Investigation, 2023, v. 43, n. 12, p. 927, doi. 10.1007/s40261-023-01317-z
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- Publication type:
- Article
Open-Label Study to Assess the Efficacy of Ipragliflozin for Reducing Insulin Dose in Patients with Type 2 Diabetes Mellitus Receiving Insulin Therapy.
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- Clinical Drug Investigation, 2019, v. 39, n. 12, p. 1213, doi. 10.1007/s40261-019-00851-z
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- Publication type:
- Article
Rationale and Design of the STOP-OB Study for Evaluating the Effects of Tofogliflozin and Glimepiride on Fat Deposition in Type 2 Diabetes Patients Treated with Metformin/DPP-4 Inhibitor Dual Therapy.
- Published in:
- Diabetes Therapy, 2018, v. 9, n. 5, p. 2117, doi. 10.1007/s13300-018-0491-4
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- Publication type:
- Article
Ipragliflozin Add-on Therapy to a GLP-1 Receptor Agonist in Japanese Patients with Type 2 Diabetes (AGATE): A 52-Week Open-Label Study.
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- Diabetes Therapy, 2018, v. 9, n. 4, p. 1549, doi. 10.1007/s13300-018-0455-8
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- Publication type:
- Article
Effect of mitochondrial and/or cytosolic glycerol 3-phosphate dehydrogenase overexpression on glucose-stimulated insulin secretion from MIN6 and HIT cells.
- Published in:
- 1996
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- Publication type:
- journal article
Glucose-regulated translational control of proinsulin biosynthesis with that of the proinsulin endopeptidases PC2 and PC3 in the insulin-producing MIN6 cell line.
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- 1996
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- Publication type:
- journal article
Upregulation of GLUT2 mRNA by glucose, mannose, and fructose in isolated rat hepatocytes.
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- 1992
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- Publication type:
- journal article
Peptide-based radioimmunoassay specific for GLUT1 glucose transporter.
- Published in:
- 1991
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- Publication type:
- journal article
Hyponatremia Associated with Prophylactic Low-Dose Trimethoprim during Systemic Corticosteroid Therapy for AQP4-Positive Optic Neuritis in a Diabetic Patient.
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- Antibiotics (2079-6382), 2020, v. 9, n. 4, p. 201, doi. 10.3390/antibiotics9040201
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- Publication type:
- Article
Expression of Glucose Transporter Isoforms with Aging.
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- Gerontology, 1992, v. 38, n. S1, p. 3, doi. 10.1159/000213355
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- Publication type:
- Article
WFS1-deficiency increases endoplasmic reticulum stress, impairs cell cycle progression and triggers the apoptotic pathway specifically in pancreatic β-cells.
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- Human Molecular Genetics, 2006, v. 15, n. 10, p. 1600, doi. 10.1093/hmg/ddl081
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- Publication type:
- Article
Disruption of the WFS1 gene in mice causes progressive β-cell loss and impaired stimulus–secretion coupling in insulin secretion.
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- Human Molecular Genetics, 2004, v. 13, n. 11, p. 1159, doi. 10.1093/hmg/ddh125
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- Publication type:
- Article
Association of Glycated Hemoglobin Level with Self-Reported Chewing Problems in Elderly Community-Dwelling Individuals in Japan.
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- Journal of Multidisciplinary Healthcare, 2023, v. 16, p. 1231, doi. 10.2147/JMDH.S404028
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- Publication type:
- Article
2101-P: Roles of Glycolysis Distinct from Mitochondrial Metabolism for Signal Generation in Insulin-Secreting Cells.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-2101-P
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- Publication type:
- Article
2179-P: Overexpression Screening Identifies Mitochondrial Carbonic Anhydrase 5b as an Important Regulator of Glucose-Stimulated Insulin Secretion in Beta Cells.
- Published in:
- Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-2179-P
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- Publication type:
- Article
Interleukin-6 enhances glucose-stimulated insulin secretion from pancreatic beta-cells: potential involvement of the PLC-IP3-dependent pathway.
- Published in:
- 2011
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- Publication type:
- journal article
Interleukin-6 Enhances Glucose-Stimulated Insulin Secretion From Pancreatic β-Cells.
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- Diabetes, 2011, v. 60, n. 2, p. 537, doi. 10.2337/db10-0796
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- Publication type:
- Article
Transcription Factor TFII-I Binds to WFS1 Protein and Dissociates in Response to Endoplasmic Reticulum Stress.
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- Diabetes, 2007, v. 56, p. A412
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- Publication type:
- Article
Dissipating excess energy stored in the liver is a potential treatment strategy for diabetes associated with obesity.
- Published in:
- 2005
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- Publication type:
- journal article
Effects of GLP-1RA and SGLT2i, Alone or in Combination, on Mouse Models of Type 2 Diabetes Representing Different Disease Stages.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 21, p. 11463, doi. 10.3390/ijms222111463
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- Publication type:
- Article
Human Islet Microtissues as an In Vitro and an In Vivo Model System for Diabetes.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 4, p. 1813, doi. 10.3390/ijms22041813
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- Publication type:
- Article
Crosstalk between Macrophages and Pancreatic β-Cells in Islet Development, Homeostasis and Disease.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 4, p. 1765, doi. 10.3390/ijms22041765
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- Publication type:
- Article
Circular RNAs as Novel Regulators of β-Cell Functions under Physiological and Pathological Conditions.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 4, p. 1503, doi. 10.3390/ijms22041503
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- Publication type:
- Article
Aortic arch calcification with pericardial fat mass detected on a single chest X-ray image is closely associated with the predictive variables of future cardiovascular disease.
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- Heart & Vessels, 2022, v. 37, n. 4, p. 654, doi. 10.1007/s00380-021-01948-2
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- Publication type:
- Article
The JNK pathway modulates expression and phosphorylation of 4E-BP1 in MIN6 pancreatic β-cells under oxidative stress conditions.
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- Cell Biochemistry & Function, 2010, v. 28, n. 5, p. 387, doi. 10.1002/cbf.1667
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- Publication type:
- Article
Diabetes mellitus not an unfavorable factor on the prognosis of hepatitis C virus-related hepatocellular carcinoma.
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- Hepatology Research, 2018, v. 48, n. 1, p. 28, doi. 10.1111/hepr.12888
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- Publication type:
- Article
Two Adult Siblings With Myotonic Dystrophy Type 1 With Different Phenotypes Presenting With Chronic Respiratory Insufficiency and Sleep Apnea Syndrome.
- Published in:
- Frontiers in Neurology, 2019, p. 1, doi. 10.3389/fneur.2019.00681
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- Publication type:
- Article
Mitochondrial diabetes mellitus-glucose-induced signaling defects and β-cell loss.
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- Muscle & Nerve, 1995, v. 18, n. S14, p. S131, doi. 10.1002/mus.880181426
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- Publication type:
- Article
Hemichorea after hypoglycemic episodes with negative MRI findings in an elderly woman with poorly controlled type 2 diabetes mellitus: a case report.
- Published in:
- 2019
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- Publication type:
- journal article
Cold exposure suppresses serum adiponectin levels through sympathetic nerve activation in mice.
- Published in:
- 2006
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- Publication type:
- journal article
Tuberculosis Relapse in the Epididymis After the Completion of Nine Months of Anti-Tuberculosis Chemotherapy in a Patient with Poorly Controlled Diabetes Mellitus.
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- Therapeutics & Clinical Risk Management, 2021, v. 17, p. 463, doi. 10.2147/TCRM.S310463
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- Publication type:
- Article
Tuberculosis Relapse in the Epididymis After the Completion of Nine Months of Anti-Tuberculosis Chemotherapy in a Patient with Poorly Controlled Diabetes Mellitus.
- Published in:
- 2021
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- Publication type:
- case study
Cardio-ankle vascular index is more closely associated than brachial-ankle pulse wave velocity with arterial damage and risk of cardiovascular disease in patients with diabetes.
- Published in:
- 2022
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- Publication type:
- journal article
Association of upregulated activity of K<sub>ATP</sub> channels with impaired insulin secretion in UCP1-expressing insulinoma cells.
- Published in:
- Journal of Physiology, 2002, v. 540, n. 3, p. 781, doi. 10.1113/jphysiol.2001.013048
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- Publication type:
- Article
Effect of Adult Weight Gain on Non-Alcoholic Fatty Liver Disease and Its Association with Anthropometric Parameters in the Lean Japanese Population.
- Published in:
- Diagnostics (2075-4418), 2020, v. 10, n. 11, p. 863, doi. 10.3390/diagnostics10110863
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- Publication type:
- Article
Islet B-cell secretion determines glucagon release from neighbouring a-cells.
- Published in:
- Nature Cell Biology, 2003, v. 5, n. 4, p. 330, doi. 10.1038/ncb951
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- Publication type:
- Article
What Couples Glycolysis to Mitochondrial Signal Generation in Glucose-Stimulated Insulin Secretion?
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- IUBMB Life, 2000, v. 49, n. 5, p. 391, doi. 10.1080/152165400410236
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- Publication type:
- Article
Impact of Female Sex on the Susceptibility to Hypernatremia Among Older Community-Dwelling Individuals in Japan.
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- International Journal of General Medicine, 2022, v. 15, p. 777, doi. 10.2147/IJGM.S345150
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- Publication type:
- Article
A Single Episode of Hypoglycemia as a Possible Early Warning Sign of Adrenal Insufficiency.
- Published in:
- 2020
- By:
- Publication type:
- case study
Elsberg syndrome related to varicella zoster virus infection with painless skin lesions in an elderly woman with poorly controlled type 2 diabetes mellitus.
- Published in:
- 2018
- By:
- Publication type:
- case study
Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells.
- Published in:
- 2010
- By:
- Publication type:
- journal article
Fibrosis-4 Index Is Closely Associated with Arterial Damage and Future Risk of Coronary Heart Disease in Type 2 Diabetes.
- Published in:
- International Journal of Hypertension, 2022, p. 1, doi. 10.1155/2022/2760027
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- Publication type:
- Article
Fibrosis-4 Index Is Closely Associated with Arterial Damage and Future Risk of Coronary Heart Disease in Type 2 Diabetes.
- Published in:
- International Journal of Hypertension, 2022, p. 1, doi. 10.1155/2022/2760027
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- Publication type:
- Article
A rare case of fulminant type 1 diabetes mellitus accompanied by both acute pancreatitis and myocarditis - case report.
- Published in:
- BMC Endocrine Disorders, 2020, v. 20, n. 1, p. N.PAG, doi. 10.1186/s12902-020-00607-3
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- Publication type:
- Article
Impact of Plasma Xanthine Oxidoreductase Activity on the Mechanisms of Distal Symmetric Polyneuropathy Development in Patients with Type 2 Diabetes.
- Published in:
- Biomedicines, 2021, v. 9, n. 8, p. 1052, doi. 10.3390/biomedicines9081052
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- Publication type:
- Article
A large-scale functional analysis of genes expressed differentially in insulin secreting MIN6 sublines with high versus mildly reduced glucose-responsiveness.
- Published in:
- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-32589-2
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- Publication type:
- Article
Seasonal variation in hydration status among community‐dwelling elderly in Japan.
- Published in:
- Geriatrics & Gerontology International, 2020, v. 20, n. 10, p. 904, doi. 10.1111/ggi.14010
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- Publication type:
- Article
Using recombinase‐mediated cassette exchange to engineer MIN6 insulin‐secreting cells based on a newly identified safe harbor locus.
- Published in:
- Journal of Diabetes Investigation, 2021, v. 12, n. 12, p. 2129, doi. 10.1111/jdi.13646
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- Publication type:
- Article