Works matching AU Irizarry, Michael C.

Results: 100
    1

    Increase in the relative expression of tau with four microtubule binding repeat regions in frontotemporal lobar degeneration and progressive supranuclear palsy brains.

    Published in:
    Acta Neuropathologica, 2007, v. 114, n. 5, p. 471, doi. 10.1007/s00401-007-0280-z
    By:
    • Ingelsson, Martin;
    • Ramasamy, Karunya;
    • Russ, Carsten;
    • Freeman, Stefanie H.;
    • Orne, Jennifer;
    • Raju, Susan;
    • Matsui, Toshifumi;
    • Growdon, John H.;
    • Frosch, Matthew P.;
    • Ghetti, Bernardino;
    • Brown, Robert H.;
    • Irizarry, Michael C.;
    • Hyman, Bradley T.
    Publication type:
    Article
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    No alteration in tau exon 10 alternative splicing in tangle-bearing neurons of the Alzheimer’s disease brain.

    Published in:
    Acta Neuropathologica, 2006, v. 112, n. 4, p. 439, doi. 10.1007/s00401-006-0095-3
    By:
    • Ingelsson, Martin;
    • Ramasamy, Karunya;
    • Cantuti-Castelvetri, Ippolita;
    • Skoglund, Lena;
    • Matsui, Toshifumi;
    • Orne, Jennifer;
    • Kowa, Hasimoto;
    • Raju, Susan;
    • Vanderburg, Charles R.;
    • Augustinack, Jean C.;
    • de Silva, Rohan;
    • Lees, Andrew J.;
    • Lannfelt, Lars;
    • Growdon, John H.;
    • Frosch, Matthew P.;
    • Standaert, David G.;
    • Irizarry, Michael C.;
    • Hyman, Bradley T.
    Publication type:
    Article
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    Plasma pTau217 ratio predicts continuous regional brain tau accumulation in amyloid‐positive early Alzheimer's disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2025, v. 21, n. 2, p. 1, doi. 10.1002/alz.14411
    By:
    • Devanarayan, Viswanath;
    • Charil, Arnaud;
    • Horie, Kanta;
    • Doherty, Thomas;
    • Llano, Daniel A.;
    • Andreozzi, Erica;
    • Sachdev, Pallavi;
    • Ye, Yuanqing;
    • Murali, Leema Krishna;
    • Zhou, Jin;
    • Reyderman, Larisa;
    • Hampel, Harald;
    • Kramer, Lynn D.;
    • Dhadda, Shobha;
    • Irizarry, Michael C.
    Publication type:
    Article
    8

    Prediction of regional brain tau levels in early Alzheimer's disease using plasma pTau217.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. S8, p. 1, doi. 10.1002/alz.095793
    By:
    • Devanarayan, Viswanath;
    • Charil, Arnaud;
    • Doherty, Thomas;
    • Llano, Daniel A.;
    • Ye, Yuanqing;
    • Andreozzi, Erica;
    • Zhou, Jin;
    • Sachdev, Pallavi;
    • Reyderman, Larisa;
    • Hampel, Harald;
    • Kramer, Lynn D;
    • Dhadda, Shobha;
    • Irizarry, Michael C.
    Publication type:
    Article
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    Lecanemab Slows Tau PET Accumulation.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. S6, p. 1, doi. 10.1002/alz.091956
    By:
    • Charil, Arnaud;
    • Cao, Youfang;
    • Willis, Brian A.;
    • Hersch, Steven;
    • Irizarry, Michael C.;
    • Reyderman, Larisa
    Publication type:
    Article
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    Lewy body dementia: Overcoming barriers and identifying solutions.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 3, p. 2298, doi. 10.1002/alz.13674
    By:
    • Agarwal, Kanishka;
    • Backler, Wendi;
    • Bayram, Ece;
    • Bloom, Leah;
    • Boeve, Bradley F.;
    • Cha, Jang‐Ho;
    • Denslow, Maria;
    • Ferman, Tanis J.;
    • Galasko, Douglas;
    • Galvin, James E.;
    • Gomperts, Stephen N.;
    • Irizarry, Michael C.;
    • Kantarci, Kejal;
    • Kaushik, Harsh;
    • Kietlinski, Matt;
    • Koenig, Aaron;
    • Leverenz, James B.;
    • McKeith, Ian;
    • McLean, Pamela J.;
    • Montine, Thomas J.
    Publication type:
    Article
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    Estimating Braak stage from [<sup>18</sup>F]MK6240 PET scans.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.083004
    By:
    • Whittington, Alex;
    • Porat, Lily;
    • Christian, Bradley T.;
    • Devanand, Devanand P.;
    • Hostetler, Eric D.;
    • Johnson, Keith A.;
    • Johnson, Sterling C;
    • Klunk, William E;
    • Lao, Patrick J.;
    • Rowe, Christopher C;
    • Devanarayan, Viswanath;
    • Reilhac, Anthonin;
    • Reyderman, Larisa;
    • Irizarry, Michael C.;
    • Charil, Arnaud;
    • Gunn, Roger N
    Publication type:
    Article
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    Harmonization of tau‐PET in Alzheimer's disease: comparison of methods to derive CenTauR units for [<sup>18</sup>F]RO948, [<sup>18</sup>F]Flortaucipir, and [<sup>18</sup>F]MK‐6240.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080421
    By:
    • Leuzy, Antoine;
    • Dore, Vincent;
    • Raket, Lars Lau;
    • Klein, Gregory;
    • Baker, Suzanne L.;
    • Carrillo, Maria C.;
    • Charil, Arnaud;
    • Collins, Emily C.;
    • Collins, Jessica A.;
    • Haeberlein, Samantha Budd;
    • Higuchi, Makoto;
    • Hostetler, Eric D.;
    • Hutchison, R. Matthew;
    • Iaccarino, Leonardo;
    • Irizarry, Michael C.;
    • Jagust, William J.;
    • Johnson, Keith A.;
    • Karten, Yashmin;
    • Kolb, Hartmuth C.;
    • Lopresti, Brian J.
    Publication type:
    Article
    29

    Harmonization of tau‐PET in Alzheimer's disease: comparison of methods to derive CenTauR units for [18F]RO948, [18F]Flortaucipir, and [18F]MK‐6240.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.082006
    By:
    • Leuzy, Antoine;
    • Dore, Vincent;
    • Raket, Lars Lau;
    • Klein, Gregory;
    • Baker, Suzanne L.;
    • Carrillo, Maria C.;
    • Charil, Arnaud;
    • Collins, Emily C.;
    • Collins, Jessica A.;
    • Haeberlein, Samantha Budd;
    • Higuchi, Makoto;
    • Hostetler, Eric D.;
    • Hutchison, R. Matthew;
    • Iaccarino, Leonardo;
    • Irizarry, Michael C.;
    • Jagust, William J.;
    • Johnson, Keith A.;
    • Karten, Yashmin;
    • Kolb, Hartmuth C.;
    • Lopresti, Brian J.
    Publication type:
    Article
    30

    The AHEAD 3‐45 Study: Design of a prevention trial for Alzheimer's disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 4, p. 1227, doi. 10.1002/alz.12748
    By:
    • Rafii, Michael S.;
    • Sperling, Reisa A.;
    • Donohue, Michael C.;
    • Zhou, Jin;
    • Roberts, Claire;
    • Irizarry, Michael C.;
    • Dhadda, Shobha;
    • Sethuraman, Gopalan;
    • Kramer, Lynn D;
    • Swanson, Chad J;
    • Li, David;
    • Krause, Stephen;
    • Rissman, Robert A.;
    • Walter, Sarah;
    • Raman, Rema;
    • Johnson, Keith A.;
    • Aisen, Paul S.
    Publication type:
    Article
    31

    Strategies for diverse participant recruitment to a preclinical Alzheimer's Disease prevention trial: The AHEAD study.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 11, p. 1, doi. 10.1002/alz.068222
    By:
    • Molina‐Henry, Doris P.;
    • Grill, Joshua;
    • Sperling, Reisa A.;
    • Aisen, Paul;
    • Clanton, Taylor;
    • Devins, Theresa;
    • Dhadda, Shobha;
    • Glover, Crystal M;
    • Irizarry, Michael C;
    • Johnson, Keith A.;
    • Kirn, Dylan;
    • Kramer, Lynn D;
    • Shum, Leona K;
    • Zhou, Jin;
    • Raman, Rema
    Publication type:
    Article
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    Diversity in Phase 2 and Phase 3 Placebo‐Controlled, Double‐Blind, Lecanemab and Elenbecestat Early Alzheimer's Disease Studies.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 10, p. 1, doi. 10.1002/alz.069198
    By:
    • Grill, Joshua;
    • Molina‐Henry, Doris P.;
    • Sperling, Reisa A.;
    • Dhadda, Shobha;
    • Tranotti, Kate;
    • Harris, Russell;
    • Devins, Theresa;
    • Swanson, Chad J;
    • Kanekiyo, Michio;
    • Gee, Michelle;
    • Irizarry, Michael C;
    • Kramer, Lynn D;
    • Aisen, Paul;
    • Raman, Rema
    Publication type:
    Article
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    Preliminary assessment of the clinical effects of lecanemab following 18 months of treatment in the open label extension of the phase 2 proof of concept study, BAN2401‐G000‐201, in subjects with early Alzheimer's disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.057780
    By:
    • Swanson, Chad J;
    • Dhadda, Shobha;
    • Irizarry, Michael C;
    • Kanekiyo, Michio;
    • Li, David JianJun;
    • Kaplow, June;
    • Gordon, Robert;
    • Heanue‐Travers, Helena;
    • Hodgkinson, Mark;
    • Kramer, Lynn D
    Publication type:
    Article
    40

    Plasma Aβ 42:40 ratio tracks with changes in brain amyloid PET SUVr in the core and open label extension of the phase 2 proof of concept study ban2401‐g000‐201 following treatment with lecanemab in subjects with early Alzheimer's disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.057760
    By:
    • Swanson, Chad J;
    • Kanekiyo, Michio;
    • Kaplow, June;
    • Dhadda, Shobha;
    • Irizarry, Michael C;
    • Koyama, Akihiko;
    • Li, David JianJun;
    • Verbel, David;
    • Gordon, Robert;
    • Heanue‐Travers, Helena;
    • Hodgkinson, Mark;
    • Kramer, Lynn D
    Publication type:
    Article
    41

    Baseline characteristics for CLARITY AD: A phase 3 placebo‐controlled, double‐blind, parallel‐group, 18‐month study evaluating lecanemab (ban2401) in early Alzheimer's disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.054331
    By:
    • Lynch, Shau Yu;
    • Irizarry, Michael C;
    • Dhadda, Shobha;
    • Li, David JianJun;
    • Kanekiyo, Michio;
    • Bogoslovsky, Tanya;
    • Gee, Michelle;
    • Reyderman, Larisa;
    • Kaplow, June;
    • Rabe, Martin;
    • Hodgkinson, Mark;
    • Kramer, Lynn D;
    • Hampel, Harald;
    • Swanson, Chad J
    Publication type:
    Article
    42

    AHEAD 3‐45 study: Preliminary screening and baseline characteristics from a placebo‐controlled, double‐blind study evaluating lecanemab in participants with preclinical Alzheimer's disease and elevated (A45 trial) and intermediate (A3 trial) amyloid

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.053143
    By:
    • Zhou, Jin;
    • Irizarry, Michael C;
    • Kramer, Lynn D;
    • Swanson, Chad J;
    • Roberts, Claire;
    • Dhadda, Shobha;
    • Li, David JianJun;
    • Rabe, Martin;
    • Krause, Stephen;
    • Raman, Rema;
    • Donohue, Michael C;
    • Sethuraman, Gopalan;
    • Johnson, Keith A.;
    • Sperling, Reisa A.;
    • Aisen, Paul S
    Publication type:
    Article
    43

    The design of Dominantly Inherited Alzheimer Disease Trial of the anti‐tau antibody, E‐2814, on the DIAN‐TU Tau Next Generation Platform.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.057320
    By:
    • Schneider, Lon S.;
    • Bateman, Randall J.;
    • Clifford, David B.;
    • McDade, Eric;
    • Wang, Guoqiao;
    • Llibre‐Guerra, Jorge J.;
    • Li, Yan;
    • Mills, Susan;
    • Santacruz, Anna;
    • Sachdev, Pallavi;
    • Li, David JianJun;
    • O'Sullivan, Stacie;
    • Yagi, Takuya;
    • Koyama, Akihiko;
    • Irizarry, Michael C.;
    • Reyderman, Larisa
    Publication type:
    Article
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    AHEAD 3‐45 study design: A global study to evaluate the efficacy and safety of treatment with BAN2401 for 216 weeks in preclinical Alzheimer's disease with intermediate amyloid (A3 trial) and elevated amyloid (A45 trial): Clinical trial design and implementation

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.044511
    By:
    • Aisen, Paul S.;
    • Zhou, Jin;
    • Irizarry, Michael C.;
    • Kramer, Lynn D;
    • Swanson, Chad J.;
    • Dhadda, Shobha;
    • Rabe, Martin;
    • Krause, Stephen;
    • Li, David JianJun;
    • Raman, Rema;
    • Donohue, Michael C.;
    • Sethuraman, Gopalan;
    • Johnson, Keith A.;
    • Sperling, Reisa A.
    Publication type:
    Article
    47

    New directions in clinical trials for frontotemporal lobar degeneration: Methods and outcome measures.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 1, p. 131, doi. 10.1016/j.jalz.2019.06.4956
    By:
    • Boxer, Adam L.;
    • Gold, Michael;
    • Feldman, Howard;
    • Boeve, Bradley F.;
    • Dickinson, Susan L.-J.;
    • Fillit, Howard;
    • Ho, Carole;
    • Paul, Robert;
    • Pearlman, Rodney;
    • Sutherland, Margaret;
    • Verma, Ajay;
    • Arneric, Stephen P.;
    • Alexander, Brian M.;
    • Dickerson, Bradford C.;
    • Dorsey, Earl Ray;
    • Grossman, Murray;
    • Huey, Edward D.;
    • Irizarry, Michael C.;
    • Marks, William J.;
    • Masellis, Mario
    Publication type:
    Article
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