Works matching AU Iriepa, Isabel
Results: 28
Donepezil + chromone + melatonin hybrids as promising agents for Alzheimer's disease therapy.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 479, doi. 10.1080/14756366.2018.1545766
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Synthesis and biological assessment of KojoTacrines as new agents for Alzheimer's disease therapy.
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- Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 163, doi. 10.1080/14756366.2018.1538136
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Structural basis of drugs that increase cardiac inward rectifier Kir2.1 currents.
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- Cardiovascular Research, 2014, v. 104, n. 2, p. 337, doi. 10.1093/cvr/cvu203
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Synthesis of N -Substituted Pyrroles Catalyzed by Low-Cost and Commercially Available Aluminas.
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- Catalysts (2073-4344), 2023, v. 13, n. 3, p. 603, doi. 10.3390/catal13030603
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Synthesis and Biological Assessment of PyrimidoTacrines as Promising Agents for Alzheimer's Disease Therapy.
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- ChemistrySelect, 2021, v. 6, n. 37, p. 9975, doi. 10.1002/slct.202102363
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Automated Synthesis of New Quinoxalinetacrines.
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- ChemistrySelect, 2020, v. 5, n. 21, p. 6491, doi. 10.1002/slct.202001593
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Synthesis of (±)‐cis‐1‐Aryl‐3‐oxo‐2,3‐dihydro‐1H‐benzo[f]chromene‐2‐carbonitriles and (±)‐trans‐4‐Aryl‐2‐oxo‐3,4‐dihydro‐2H‐benzo[h]chromene‐3‐carbonitriles
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- ChemistrySelect, 2019, v. 4, n. 44, p. 12902, doi. 10.1002/slct.201903982
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Cs<sub>2</sub>CO<sub>3</sub>‐Promoted Alkylation of 3‐Cyano‐2(1H)‐Pyridones: Anticancer Evaluation and Molecular Docking.
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- ChemPlusChem, 2024, v. 89, n. 9, p. 1, doi. 10.1002/cplu.202400172
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Multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease: design, synthesis, biochemical evaluation, ADMET, molecular modeling, and QSAR analysis of novel donepezil-pyridyl hybrids.
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- Drug Design, Development & Therapy, 2014, v. 8, p. 1893, doi. 10.2147/DDDT.S69258
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Chemical and Pharmacological Studies on Enantiomerically Pure p-Methoxytacripyrines, Promising Multi-Target-Directed Ligands for the Treatment of Alzheimer's Disease.
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- ChemMedChem, 2011, v. 6, n. 11, p. 1990, doi. 10.1002/cmdc.201100239
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Exploring the Potential of Sulfonamide-Dihydropyridine Hybrids as Multitargeted Ligands for Alzheimer's Disease Treatment.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 11, p. 9742, doi. 10.3390/ijms24119742
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Homo-Tris-Nitrones Derived from α-Phenyl- N-tert -butylnitrone: Synthesis, Neuroprotection and Antioxidant Properties.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 21, p. 7949, doi. 10.3390/ijms21217949
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Synthesis of Hantzsch Adducts as Cholinesterases and Calcium Flux inhibitors, Antioxidants and Neuroprotectives.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 20, p. 7652, doi. 10.3390/ijms21207652
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Acetylcholinesterase Inhibition of Diversely Functionalized Quinolinones for Alzheimer's Disease Therapy.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 11, p. 3913, doi. 10.3390/ijms21113913
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N -Hydroxy- N -Propargylamide Derivatives of Ferulic Acid: Inhibitors of Cholinesterases and Monoamine Oxidases.
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- Molecules, 2022, v. 27, n. 21, p. 7437, doi. 10.3390/molecules27217437
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Triazolopyridopyrimidine: A New Scaffold for Dual-Target Small Molecules for Alzheimer's Disease Therapy.
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- Molecules, 2020, v. 25, n. 14, p. 3190, doi. 10.3390/molecules25143190
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QuinoxalineTacrine QT78, a Cholinesterase Inhibitor as a Potential Ligand for Alzheimer's Disease Therapy.
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- Molecules, 2019, v. 24, n. 8, p. 1503, doi. 10.3390/molecules24081503
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Exploiting the Chalcone Scaffold to Develop Multifunctional Agents for Alzheimer’s Disease.
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- Molecules, 2018, v. 23, n. 8, p. 1902, doi. 10.3390/molecules23081902
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Imidazopyranotacrines as Non-Hepatotoxic, Selective Acetylcholinesterase Inhibitors, and Antioxidant Agents for Alzheimer1s Disease Therapy.
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- Molecules, 2016, v. 21, n. 4, p. 400, doi. 10.3390/molecules21040400
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- Article
Polyfunctionalized α-Phenyl-tert-butyl(benzyl)nitrones: Multifunctional Antioxidants for Stroke Treatment.
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- Antioxidants, 2022, v. 11, n. 9, p. 1735, doi. 10.3390/antiox11091735
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Synthesis and Antioxidant Properties of HeteroBisNitrones Derived from Benzene Dicarbaldehydes.
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- Antioxidants, 2022, v. 11, n. 8, p. N.PAG, doi. 10.3390/antiox11081575
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Privileged Quinolylnitrones for the Combined Therapy of Ischemic Stroke and Alzheimer's Disease.
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- Pharmaceuticals (14248247), 2021, v. 14, n. 9, p. 861, doi. 10.3390/ph14090861
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Tacrines as Therapeutic Agents for Alzheimer's Disease. V. Recent Developments.
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- Chemical Record, 2021, v. 21, n. 1, p. 162, doi. 10.1002/tcr.202000107
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2-{ N -[ω-(1-Benzylpiperidin-4-yl)alkyl]amino}-6-[(prop-2-yn-1-yl)amino]pyridine-3,5-dicarbonitriles Showing High Affinity for σ 1/2 Receptors.
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- International Journal of Molecular Sciences, 2025, v. 26, n. 3, p. 1266, doi. 10.3390/ijms26031266
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Multipotente Liganden mit kombinierter Cholinesterase- und Monoaminooxidase-Inhibition sowie Histamin-H<sub>3</sub>R-Antagonismus bei neurodegenerativen Erkrankungen.
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- Angewandte Chemie, 2017, v. 129, n. 41, p. 12939, doi. 10.1002/ange.201706072
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Synthesis, antioxidant properties and neuroprotection of α-phenyl-tert-butylnitrone derived HomoBisNitrones in in vitro and in vivo ischemia models.
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- Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-70690-y
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Nitric oxide blocks hKv1.5 channels by S-nitrosylation and by a cyclic GMP-dependent mechanism
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- Cardiovascular Research, 2006, v. 72, n. 1, p. 80, doi. 10.1016/j.cardiores.2006.06.021
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Multitarget-Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H<sub>3</sub>R Antagonism for Neurodegenerative Diseases.
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- Angewandte Chemie International Edition, 2017, v. 56, n. 41, p. 12765, doi. 10.1002/anie.201706072
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