Works by Iori, Renato

Results: 55

Bioactivated Glucoraphanin Modulates Genes Involved in Necroptosis on Motor-Neuron-like Nsc-34: A Transcriptomic Study.

Published in:

Antioxidants, 2024, v. 13, n. 9, p. 1111, doi. 10.3390/antiox13091111

By:

Minuti, Aurelio;
Trainito, Alessandra;
Gugliandolo, Agnese;
Anchesi, Ivan;
Chiricosta, Luigi;
Iori, Renato;
Mazzon, Emanuela;
Calabrò, Marco

Publication type:

Article

α-Cyclodextrin/Moringin Induces an Antioxidant Transcriptional Response Activating Nrf2 in Differentiated NSC-34 Motor Neurons.

Published in:

Antioxidants, 2024, v. 13, n. 7, p. 813, doi. 10.3390/antiox13070813

By:

Gugliandolo, Agnese;
Calì, Gabriella;
Muscarà, Claudia;
Artimagnella, Osvaldo;
Rollin, Patrick;
Perenzoni, Daniele;
Iori, Renato;
Mazzon, Emanuela;
Chiricosta, Luigi

Publication type:

Article

Erratum to: A glucosinolate-rich extract of Japanese Daikon perturbs carcinogen-metabolizing enzyme systems in rat, being a potent inducer of hepatic glutathione S-transferase.

Published in:

2013

By:

Abdull Razis, Ahmad;
Nicola, Gina;
Pagnotta, Eleonora;
Iori, Renato;
Ioannides, Costas

Publication type:

Correction Notice

A glucosinolate-rich extract of Japanese Daikon perturbs carcinogen-metabolizing enzyme systems in rat, being a potent inducer of hepatic glutathione S-transferase.

Published in:

European Journal of Nutrition, 2013, v. 52, n. 3, p. 1279, doi. 10.1007/s00394-012-0397-2

By:

Abdull Razis, Ahmad;
Nicola, Gina;
Pagnotta, Eleonora;
Iori, Renato;
Ioannides, Costas

Publication type:

Article

Isatis canescens is a rich source of glucobrassicin and other health-promoting compounds.

Published in:

Journal of the Science of Food & Agriculture, 2015, v. 95, n. 1, p. 158, doi. 10.1002/jsfa.6697

By:

Galletti, Stefania;
Bagatta, Manuela;
Branca, Ferdinando;
Argento, Sergio;
De Nicola, Gina Rosalinda;
Cianchetta, Stefano;
Iori, Renato;
Ninfali, Paolino

Publication type:

Article

Glucobrassicin enhancement in woad ( Isatis tinctoria) leaves by chemical and physical treatments.

Published in:

Journal of the Science of Food & Agriculture, 2006, v. 86, n. 12, p. 1833, doi. 10.1002/jsfa.2571

By:

Galletti, Stefania;
Barillari, Jessica;
Iori, Renato;
Venturi, Gianpietro

Publication type:

Article

Purification of major glucosinolates from Brassicaceae seeds and preparation of isothiocyanate and amine metabolites.

Published in:

Journal of the Science of Food & Agriculture, 2006, v. 86, n. 8, p. 1271, doi. 10.1002/jsfa.2488

By:

Song, Lijiang;
Iori, Renato;
Thornalley, Paul J

Publication type:

Article

Dose-dependent effects of R-sulforaphane isothiocyanate on the biology of human mesenchymal stem cells, at dietary amounts, it promotes cell proliferation and reduces senescence and apoptosis, while at anti-cancer drug doses, it has a cytotoxic effect.

Published in:

Age (0161-9152), 2012, v. 34, n. 2, p. 281, doi. 10.1007/s11357-011-9231-7

By:

Zanichelli, Fulvia;
Capasso, Stefania;
Cipollaro, Marilena;
Pagnotta, Eleonora;
Cartenì, Maria;
Casale, Fiorina;
Iori, Renato;
Galderisi, Umberto

Publication type:

Article

A Combination of Moringin and Avenanthramide 2f Inhibits the Proliferation of Hep3B Liver Cancer Cells Inducing Intrinsic and Extrinsic Apoptosis.

Published in:

Nutrition & Cancer, 2018, v. 70, n. 7, p. 1159, doi. 10.1080/01635581.2018.1497672

By:

Antonini, Elena;
Iori, Renato;
Ninfali, Paolino;
Scarpa, Emanuele Salvatore

Publication type:

Article

Breakdown products of neoglucobrassicin inhibit activation of Nrf2 target genes mediated by myrosinase-derived glucoraphanin hydrolysis products.

Published in:

Biological Chemistry, 2010, v. 391, n. 12, p. 1281, doi. 10.1515/BC.2010.134

By:

Haack, Michael;
Löwinger, Maria;
Lippmann, Doris;
Kipp, Anna;
Pagnotta, Eleonora;
Iori, Renato;
Monien, Bernhard H.;
Glatt, Hansruedi;
Brauer, Martin N.;
Wessjohann, Ludger A.;
Brigelius-Flohé, Regina

Publication type:

Article

Breakdown products of neoglucobrassicin inhibit activation of Nrf2 target genes mediated by myrosinase-derived glucoraphanin hydrolysis products.

Published in:

Biological Chemistry, 2010, v. 391, n. 11, p. 1281, doi. 10.1515/BC.2010.134

By:

Haack, Michael;
Löwinger, Maria;
Lippmann, Doris;
Kipp, Anna;
Pagnotta, Eleonora;
Iori, Renato;
Monien, Bernhard H.;
Glatt, Hansruedi;
Brauer, Martin N.;
Wessjohann, Ludger A.;
Brigelius-Flohé, Regina

Publication type:

Article

Retraction Note: Moringa isothiocyanate complexed with α-cyclodextrin: a new perspective in neuroblastoma treatment.

Published in:

BMC Complementary Medicine & Therapies, 2023, v. 23, n. 1, p. 1, doi. 10.1186/s12906-023-03908-x

By:

Giacoppo, Sabrina;
Iori, Renato;
Rollin, Patrick;
Bramanti, Placido;
Mazzon, Emanuela

Publication type:

Article

Moringin activates Wnt canonical pathway by inhibiting GSK3β in a mouse model of experimental autoimmune encephalomyelitis.

Published in:

Drug Design, Development & Therapy, 2016, v. 10, p. 3291, doi. 10.2147/DDDT.S110514

By:

Giacoppo, Sabrina;
Rajan, Thangavelu Soundara;
De Nicola, Gina Rosalinda;
Iori, Renato;
Bramanti, Placido;
Mazzon, Emanuela

Publication type:

Article

The Chemopreventive Phytochemical Moringin Isolated from Moringa oleifera Seeds Inhibits JAK/STAT Signaling.

Published in:

PLoS ONE, 2016, v. 11, n. 6, p. 1, doi. 10.1371/journal.pone.0157430

By:

Michl, Carina;
Vivarelli, Fabio;
Weigl, Julia;
De Nicola, Gina Rosalinda;
Canistro, Donatella;
Paolini, Moreno;
Iori, Renato;
Rascle, Anne

Publication type:

Article

Raphanus sativus cv. Sango Sprout Juice Decreases Diet-Induced Obesity in Sprague Dawley Rats and Ameliorates Related Disorders.

Published in:

PLoS ONE, 2016, v. 11, n. 3, p. 1, doi. 10.1371/journal.pone.0150913

By:

Vivarelli, Fabio;
Canistro, Donatella;
Sapone, Andrea;
De Nicola, Gina Rosalinda;
Babot Marquillas, Clara;
Iori, Renato;
Antonazzo, Ippazio Cosimo;
Gentilini, Fabio;
Paolini, Moreno

Publication type:

Article

Treatment of Periodontal Ligament Stem Cells with MOR and CBD Promotes Cell Survival and Neuronal Differentiation via the PI3K/Akt/mTOR Pathway.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 8, p. 2341, doi. 10.3390/ijms19082341

By:

Lanza Cariccio, Veronica;
Scionti, Domenico;
Raffa, Antonio;
Iori, Renato;
Pollastro, Federica;
Diomede, Francesca;
Bramanti, Placido;
Trubiani, Oriana;
Mazzon, Emanuela

Publication type:

Article

Antioxidant and Pro-Oxidant Capacities of ITCs.

Published in:

Environmental & Molecular Mutagenesis, 2009, v. 50, n. 3, p. 222, doi. 10.1002/em.20468

By:

Valgimigli, Luca;
Iori, Renato

Publication type:

Article

Hydrolysis of glucosinolates using nylon-immobilized myrosinase to produce pure bioactive molecules.

Published in:

Biotechnology & Bioengineering, 2000, v. 68, n. 6, p. 660, doi. 10.1002/(SICI)1097-0290(20000620)68:6<660::AID-BIT9>3.0.CO;2-L

By:

Leoni, Onofrio;
Iori, Renato;
Palmieri, Sandro

Publication type:

Article

Human gingival mesenchymal stem cells pretreated with vesicular moringin nanostructures as a new therapeutic approach in a mouse model of spinal cord injury.

Published in:

Journal of Tissue Engineering & Regenerative Medicine, 2019, v. 13, n. 7, p. 1109, doi. 10.1002/term.2857

By:

Mammana, Santa;
Gugliandolo, Agnese;
Cavalli, Eugenio;
Diomede, Francesca;
Iori, Renato;
Zappacosta, Romina;
Bramanti, Placido;
Conti, Pio;
Fontana, Antonella;
Pizzicannella, Jacopo;
Mazzon, Emanuela

Publication type:

Article

Identification of glucosinolate congeners able to form DNA adducts and to induce mutations upon activation by myrosinase.

Published in:

Molecular Nutrition & Food Research, 2011, v. 55, n. 5, p. 783, doi. 10.1002/mnfr.201000352

By:

Baasanjav-Gerber, Chimgee;
Monien, Bernhard Hans;
Mewis, Inga;
Schreiner, Monika;
Barillari, Jessica;
Iori, Renato;
Glatt, Hansruedi

Publication type:

Article

Topical moringin cream relieves neuropathic pain by suppression of inflammatory pathway and voltage-gated ion channels in murine model of multiple sclerosis.

Published in:

Molecular Pain, 2017, v. 13, p. 1, doi. 10.1177/1744806917724318

By:

Giacoppo, Sabrina;
Iori, Renato;
Bramanti, Placido;
Mazzon, Emanuela

Publication type:

Article

Topical moringin-cream relieves neuropathic pain by suppression of inflammatory pathway and voltage-gated ion channels in murine model of multiple sclerosis.

Published in:

Molecular Pain, 2017, v. 13, p. 1, doi. 10.1177/1744806917724318

By:

Giacoppo, Sabrina;
Iori, Renato;
Bramanti, Placido;
Mazzon, Emanuela

Publication type:

Article

The naturally occurring aliphatic isothiocyanates sulforaphane and erucin are weak agonists but potent non-competitive antagonists of the aryl hydrocarbon receptor.

Published in:

Archives of Toxicology, 2012, v. 86, n. 10, p. 1505, doi. 10.1007/s00204-012-0875-6

By:

Abdull Razis, Ahmad;
Hanlon, Natalya;
Soltys, Ewa;
Krizova, Veronika;
Iori, Renato;
Plant, Kathryn;
Plant, Nick;
Ioannides, Costas

Publication type:

Article

4-Methylsulfanyl-3-butenyl isothiocyanate derived from glucoraphasatin is a potent inducer of rat hepatic phase II enzymes and a potential chemopreventive agent.

Published in:

Archives of Toxicology, 2012, v. 86, n. 2, p. 183, doi. 10.1007/s00204-011-0750-x

By:

Abdull Razis, Ahmed;
Nicola, Gina;
Pagnotta, Eleonora;
Iori, Renato;
Ioannides, Costas

Publication type:

Article

Induction of epoxide hydrolase and glucuronosyl transferase by isothiocyanates and intact glucosinolates in precision-cut rat liver slices: importance of side-chain substituent and chirality.

Published in:

Archives of Toxicology, 2011, v. 85, n. 8, p. 919, doi. 10.1007/s00204-010-0629-2

By:

Abdull Razis, Ahmad Faizal;
Bagatta, Manuela;
De Nicola, Gina Rosalinda;
Iori, Renato;
Ioannides, Costas

Publication type:

Article

The natural chemopreventive phytochemical R-sulforaphane is a far more potent inducer of the carcinogen-detoxifying enzyme systems in rat liver and lung than the S-isomer.

Published in:

International Journal of Cancer, 2011, v. 128, n. 12, p. 2775, doi. 10.1002/ijc.25620

By:

Abdull Razis, Ahmad Faizal;
Iori, Renato;
Ioannides, Costas

Publication type:

Article

Bioactivated Glucoraphanin Improves Cell Survival, Upregulating Phospho-AKT, and Modulates Genes Involved in DNA Repair in an In Vitro Alzheimer's Disease Model: A Network-Transcriptomic Analysis.

Published in:

Nutrients, 2024, v. 16, n. 23, p. 4202, doi. 10.3390/nu16234202

By:

Minuti, Aurelio;
Mazzon, Emanuela;
Iori, Renato;
Chiricosta, Luigi;
Artimagnella, Osvaldo

Publication type:

Article

Glucoraphanin Increases Intracellular Hydrogen Sulfide (H 2 S) Levels and Stimulates Osteogenic Differentiation in Human Mesenchymal Stromal Cell.

Published in:

Nutrients, 2022, v. 14, n. 3, p. 435, doi. 10.3390/nu14030435

By:

Gambari, Laura;
Barone, Marli;
Amore, Emanuela;
Grigolo, Brunella;
Filardo, Giuseppe;
Iori, Renato;
Citi, Valentina;
Calderone, Vincenzo;
Grassi, Francesco

Publication type:

Article

Induction of Apoptosis and Cytotoxicity by Isothiocyanate Sulforaphene in Human Hepatocarcinoma HepG2 Cells.

Published in:

Nutrients, 2018, v. 10, n. 6, p. 718, doi. 10.3390/nu10060718

By:

Kntayya, Saie Brindha;
Ibrahim, Muhammad Din;
Mohd Ain, Nooraini;
Iori, Renato;
Ioannides, Costas;
Abdull Razis, Ahmad Faizal

Publication type:

Article

Sulforaphane Modulates Cell Cycle and Apoptosis in Transformed and Non-transformed Human T Lymphocytes.

Published in:

Annals of the New York Academy of Sciences, 2004, v. 1010, n. 1, p. 393, doi. 10.1196/annals.1299.072

By:

FIMOGNARI, CARMELA;
NÜSSE, MICHAEL;
BERTI, FAUSTO;
IORI, RENATO;
CANTELLI‐FORTI, GIORGIO;
HRELIA, PATRIZIA

Publication type:

Article

Sulfur-containing metabolites in radishes. Further exploration of glucoraphenin desulfation.

Published in:

Journal of Sulfur Chemistry, 2013, v. 34, n. 1/2, p. 48, doi. 10.1080/17415993.2012.711332

By:

De Nicola, GinaR.;
Tatibouët, Arnaud;
Iori, Renato;
Rollin, Patrick

Publication type:

Article

A recombinant β-O-glucosidase from Caldocellum saccharolyticum to hydrolyse desulfo-glucosinolates.

Published in:

Biotechnology Letters, 2001, v. 23, n. 6, p. 443, doi. 10.1023/A:1010322322867

By:

Wathelet, Jean-Paul;
Iori, Renato;
Leoni, Onofrio;
Rollin, Patrick;
Mabon, Nicolas;
Marlier, Michel;
Palmieri, Sandro

Publication type:

Article

Low concentrations of isothiocyanates protect mesenchymal stem cells from oxidative injuries, while high concentrations exacerbate DNA damage.

Published in:

Apoptosis, 2012, v. 17, n. 9, p. 964, doi. 10.1007/s10495-012-0740-3

By:

Zanichelli, Fulvia;
Capasso, Stefania;
Bernardo, Giovanni;
Cipollaro, Marilena;
Pagnotta, Eleonora;
Cartenì, Maria;
Casale, Fiorina;
Iori, Renato;
Giordano, Antonio;
Galderisi, Umberto

Publication type:

Article

The combined effect of Sango sprout juice and caloric restriction on metabolic disorders and gut microbiota composition in an obesity model.

Published in:

2018

By:

Vivarelli, Fabio;
Canistro, Donatella;
Babot Marquillas, Clara;
Cirillo, Silvia;
De Nicola, Gina R.;
Iori, Renato;
Biagi, Giacomo;
Pinna, Carlo;
Gentilini, Fabio;
Pozzo, Luisa;
Longo, Vincenzo;
Paolini, Moreno

Publication type:

journal article

Tuscan black kale sprout extract bioactivated with myrosinase: a novel natural product for neuroprotection by inflammatory and oxidative response during cerebral ischemia/reperfusion injury in rat.

Published in:

BMC Complementary & Alternative Medicine, 2015, v. 15, p. 1, doi. 10.1186/s12906-015-0929-4

By:

Giacoppo, Sabrina;
Galuppo, Maria;
Nicola, Gina Rosalinda De;
Iori, Renato;
Bramanti, Placido;
Mazzon, Emanuela

Publication type:

Article

Novel Gram-Scale Production of Enantiopure R-Sulforaphane from Tuscan Black Kale Seeds.

Published in:

Molecules, 2014, v. 19, n. 6, p. 6975, doi. 10.3390/molecules19066975

By:

De Nicola, Gina Rosalinda;
Rollin, Patrick;
Mazzon, Emanuela;
Iori, Renato

Publication type:

Article

Antibacterial Activity of Glucomoringin Bioactivated with Myrosinase against Two Important Pathogens Affecting the Health of Long-Term Patients in Hospitals.

Published in:

Molecules, 2013, v. 18, n. 11, p. 14340, doi. 10.3390/molecules181114340

By:

Galuppo, Maria;
De Nicola, Gina Rosalinda;
Iori, Renato;
Dell'Utri, Pia;
Bramanti, Placido;
Mazzon, Emanuela

Publication type:

Article

The α-cyclodextrin complex of the Moringa isothiocyanate suppresses lipopolysaccharide-induced inflammation in RAW 264.7 macrophage cells through Akt and p38 inhibition.

Published in:

Inflammation Research, 2017, v. 66, n. 6, p. 487, doi. 10.1007/s00011-017-1033-7

By:

Giacoppo, Sabrina;
Rajan, Thangavelu;
Iori, Renato;
Rollin, Patrick;
Bramanti, Placido;
Mazzon, Emanuela

Publication type:

Article

Administration of 4-(α-L-Rhamnosyloxy)-benzyl Isothiocyanate Delays Disease Phenotype in SOD1<sup>G93A</sup> Rats: A Transgenic Model of Amyotrophic Lateral Sclerosis.

Published in:

BioMed Research International, 2015, v. 2015, p. 1, doi. 10.1155/2015/259417

By:

Galuppo, Maria;
Giacoppo, Sabrina;
Iori, Renato;
De Nicola, Gina Rosalinda;
Bramanti, Placido;
Mazzon, Emanuela

Publication type:

Article

Sulforaphane but not ascorbigen, indole-3-carbinole and ascorbic acid activates the transcription factor Nrf2 and induces phase-2 and antioxidant enzymes in human keratinocytes in culture.

Published in:

Experimental Dermatology, 2010, v. 19, n. 2, p. 137, doi. 10.1111/j.1600-0625.2009.00928.x

By:

Wagner, Anika E.;
Ernst, Insa;
Iori, Renato;
Desel, Christine;
Rimbach, Gerald

Publication type:

Article

Glucosinolate Profiling and Antimicrobial Screening of Aurinia leucadea (Brassicaceae).

Published in:

Chemistry & Biodiversity, 2011, v. 8, n. 12, p. 2310, doi. 10.1002/cbdv.201100169

By:

Blažević, Ivica;
Radonić, Ani;
Skočibušić, Mirjana;
De Nicola, Gina R.;
Montaut, Sabine;
Iori, Renato;
Rollin, Patrick;
Mastelić, Josip;
Zekić, Marina;
Maravić, Ana

Publication type:

Article

Glucosinolate Distribution in Aerial Parts of Degenia velebitica.

Published in:

Chemistry & Biodiversity, 2011, v. 8, n. 11, p. 2090, doi. 10.1002/cbdv.201100114

By:

De Nicola, Gina R.;
Blažević, Ivica;
Montaut, Sabine;
Rollin, Patrick;
Mastelić, Josip;
Iori, Renato;
Tatibouët, Arnaud

Publication type:

Article

Detection of genotoxicants in Brassicales using endogenous DNA as a surrogate target and adducts determined by 32P-postlabelling as an experimental end point.

Published in:

Mutagenesis, 2011, v. 26, n. 3, p. 407, doi. 10.1093/mutage/geq108

By:

Baasanjav-Gerber, Chimgee;
Hollnagel, Heli Miriam;
Brauchmann, Jana;
Iori, Renato;
Glatt, Hansruedi

Publication type:

Article

Glutathione peroxidase-2 and selenium decreased inflammation and tumors in a mouse model of inflammation-associated carcinogenesis whereas sulforaphane effects differed with selenium supply.

Published in:

Carcinogenesis, 2012, v. 33, n. 3, p. 620, doi. 10.1093/carcin/bgr288

By:

Krehl, Susanne;
Loewinger, Maria;
Florian, Simone;
Kipp, Anna P.;
Banning, Antje;
Wessjohann, Ludger A.;
Brauer, Martin N.;
Iori, Renato;
Esworthy, Robert S.;
Chu, Fong-Fong;
Brigelius-Flohé, Regina

Publication type:

Article

Induction of cytochrome P450, generation of oxidative stress and in vitro cell-transforming and DNA-damaging activities by glucoraphanin, the bioprecursor of the chemopreventive agent sulforaphane found in broccoli.

Published in:

Carcinogenesis, 2004, v. 25, n. 1, p. 61

By:

Moreno Paolini;
Paolo Perocco;
Donatella Canistro;
Luca Valgimigli;
Gian Franco Pedulli;
Renato Iori;
Clara Della Croce;
Giorgio Cantelli-Forti;
Marvin S. Legator;
Sherif Z. Abdel-Rahman

Publication type:

Article

Growth inhibition, cell-cycle arrest and apoptosis in human T-cell leukemia by the isothiocyanate sulforaphane.

Published in:

Carcinogenesis, 2002, v. 23, n. 4, p. 581, doi. 10.1093/carcin/23.4.581

By:

Fimognari, Carmela;
Nüsse, Michael;
Cesari, Rossano;
Iori, Renato;
Cantelli-Forti, Giorgio;
Hrelia, Patrizia

Publication type:

Article

Moringa isothiocyanate complexed with α-cyclodextrin: a new perspective in neuroblastoma treatment.

Published in:

BMC Complementary & Alternative Medicine, 2017, v. 17, p. 1, doi. 10.1186/s12906-017-1876-z

By:

Giacoppo, Sabrina;
Iori, Renato;
Rollin, Patrick;
Bramanti, Placido;
Mazzon, Emanuela

Publication type:

Article

Effect of glucoraphanin and sulforaphane against chemotherapy-induced neuropathic pain: Kv7 potassium channels modulation by H<sub>2</sub> S release in vivo.

Published in:

2018

By:

Lucarini, Elena;
Micheli, Laura;
Trallori, Elena;
Citi, Valentina;
Martelli, Alma;
Testai, Lara;
De Nicola, Gina Rosalinda;
Iori, Renato;
Calderone, Vincenzo;
Ghelardini, Carla;
Di Cesare Mannelli, Lorenzo

Publication type:

journal article

Induction of Apoptosis by Gluconasturtiin-Isothiocyanate (GNST-ITC) in Human Hepatocarcinoma HepG2 Cells and Human Breast Adenocarcinoma MCF-7 Cells.

Published in:

Molecules, 2020, v. 25, n. 5, p. 1240, doi. 10.3390/molecules25051240

By:

Arumugam, Asvinidevi;
Ibrahim, Muhammad Din;
Kntayya, Saie Brindha;
Mohd Ain, Nooraini;
Iori, Renato;
Galletti, Stefania;
Ioannides, Costas;
Abdull Razis, Ahmad Faizal;
Pecháňová, Olga

Publication type:

Article

Moringin Pretreatment Inhibits the Expression of Genes Involved in Mitophagy in the Stem Cell of the Human Periodontal Ligament.

Published in:

Molecules, 2019, v. 24, n. 18, p. 3217, doi. 10.3390/molecules24183217

By:

Chiricosta, Luigi;
Gugliandolo, Agnese;
Diomede, Francesca;
Pizzicannella, Jacopo;
Trubiani, Oriana;
Iori, Renato;
Tardiolo, Giuseppe;
Guarnieri, Simone;
Bramanti, Placido;
Mazzon, Emanuela

Publication type:

Article