Works by Ioannides, Costas
Results: 41
A principal mechanism for the cancer chemopreventive activity of phenethyl isothiocyanate is modulation of carcinogen metabolism.
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- Drug Metabolism Reviews, 2015, v. 47, n. 3, p. 356, doi. 10.3109/03602532.2015.1058819
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- Article
The Effects of Nutrition on Chemical Toxicity.
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- Drug Metabolism Reviews, 1994, v. 26, n. 4, p. 739, doi. 10.3109/03602539408998325
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- Article
Modulation of hepatic cytochromes P450 and phase II enzymes by dietary doses of sulforaphane in rats: Implications for its chemopreventive activity.
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- International Journal of Cancer, 2005, v. 117, n. 3, p. 356, doi. 10.1002/ijc.21191
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- Article
Enhancement of hepatic microsomal drug metabolism in vitro followingethanol administration
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- Xenobiotica, 1975, v. 5, n. 11, p. 665
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- Publication type:
- Article
Differential modulation of the genotoxicity of food carcinogens by naturally occurring monomeric and dimeric polyphenolics.
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- Environmental & Molecular Mutagenesis, 2000, v. 35, n. 2, p. 86, doi. 10.1002/(SICI)1098-2280(2000)35:2<86::AID-EM3>3.0.CO;2-B
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- Article
Contribution of theafulvins to the antimutagenicity of black tea: their mechanism of action.
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- Mutagenesis, 1998, v. 13, n. 6, p. 631, doi. 10.1093/mutage/13.6.631
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- Article
Modulation of the mutagenicity of food carcinogens by oligomeric and polymeric procyanidins isolated from grape seeds: synergistic genotoxicity with N-nitrosopyrrolidine.
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- Journal of the Science of Food & Agriculture, 2000, v. 80, n. 1, p. 91, doi. 10.1002/(SICI)1097-0010(20000101)80:1<91::AID-JSFA494>3.0.CO;2-E
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- Article
Fractionation of green tea extracts: correlation of antimutagenic effect with flavanol content.
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- Journal of the Science of Food & Agriculture, 1997, v. 75, n. 4, p. 453, doi. 10.1002/(SICI)1097-0010(199712)75:4<453::AID-JSFA897>3.0.CO;2-3
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- Article
Comparative mutagenicity studies on fried minced beef, grilled sausage and grilled hamburgers.
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- Journal of the Science of Food & Agriculture, 1988, v. 42, n. 4, p. 343, doi. 10.1002/jsfa.2740420408
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- Article
Exposure to Isothiocyanates Suppresses Urinary Mutagenicity in Rats Treated With Heterocyclic Amine IQ: Lack of Association With CYP1 Activity.
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- Nutrition & Cancer, 2011, v. 63, n. 2, p. 300, doi. 10.1080/01635581.2011.530735
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- Article
Fate of the Mushroom Hydrazine Agaritine in the Rat and Mouse.
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- Nutrition & Cancer, 2000, v. 37, n. 1, p. 55, doi. 10.1207/S15327914NC3701_7
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- Article
Up-regulation of cytochrome P450 and phase II enzymes by xenobiotics in precision-cut tissue slices.
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- Xenobiotica, 2013, v. 43, n. 1, p. 15, doi. 10.3109/00498254.2012.698766
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- Article
Preface.
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- Xenobiotica, 2013, v. 43, n. 1, p. 1, doi. 10.3109/00498254.2013.735827
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- Article
David Francis Victor Lewis (1949-2012).
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- Xenobiotica, 2012, v. 42, n. 8, p. 822, doi. 10.3109/00498254.2012.699220
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- Article
Professor George Gordon Gibson (1949–2008).
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- 2009
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- Obituary
Synergistic and antagonistic interactions of binary mixtures of polycyclic aromatic hydrocarbons in the upregulation of CYP1 activity and mRNA levels in precision-cut rat liver slices.
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- Environmental Toxicology, 2017, v. 32, n. 3, p. 764, doi. 10.1002/tox.22276
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- Article
Erratum to: A glucosinolate-rich extract of Japanese Daikon perturbs carcinogen-metabolizing enzyme systems in rat, being a potent inducer of hepatic glutathione S-transferase.
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- 2013
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- Correction Notice
A glucosinolate-rich extract of Japanese Daikon perturbs carcinogen-metabolizing enzyme systems in rat, being a potent inducer of hepatic glutathione S-transferase.
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- European Journal of Nutrition, 2013, v. 52, n. 3, p. 1279, doi. 10.1007/s00394-012-0397-2
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- Article
Drug–phytochemical interactions.
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- Inflammopharmacology, 2003, v. 11, n. 1, p. 7, doi. 10.1163/156856003321547103
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- Article
Neuroprotective Effects of 7-Geranyloxycinnamic Acid from Melicope lunu ankenda Leaves.
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- Molecules, 2020, v. 25, n. 16, p. 3724, doi. 10.3390/molecules25163724
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- Article
Induction of Apoptosis by Gluconasturtiin-Isothiocyanate (GNST-ITC) in Human Hepatocarcinoma HepG2 Cells and Human Breast Adenocarcinoma MCF-7 Cells.
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- Molecules, 2020, v. 25, n. 5, p. 1240, doi. 10.3390/molecules25051240
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- Article
Induction of Apoptosis and Cytotoxicity by Raphasatin in Human Breast Adenocarcinoma MCF-7 Cells.
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- Molecules, 2018, v. 23, n. 12, p. 3092, doi. 10.3390/molecules23123092
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- Publication type:
- Article
The naturally occurring aliphatic isothiocyanates sulforaphane and erucin are weak agonists but potent non-competitive antagonists of the aryl hydrocarbon receptor.
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- Archives of Toxicology, 2012, v. 86, n. 10, p. 1505, doi. 10.1007/s00204-012-0875-6
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- Article
4-Methylsulfanyl-3-butenyl isothiocyanate derived from glucoraphasatin is a potent inducer of rat hepatic phase II enzymes and a potential chemopreventive agent.
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- Archives of Toxicology, 2012, v. 86, n. 2, p. 183, doi. 10.1007/s00204-011-0750-x
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- Article
Induction of epoxide hydrolase and glucuronosyl transferase by isothiocyanates and intact glucosinolates in precision-cut rat liver slices: importance of side-chain substituent and chirality.
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- Archives of Toxicology, 2011, v. 85, n. 8, p. 919, doi. 10.1007/s00204-010-0629-2
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- Article
Phenethyl isocyanate is not the metabolite of phenethyl isothiocyanate responsible for mechanism-based inhibition of cytochrome P450.
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- Archives of Toxicology, 2010, v. 84, n. 10, p. 751, doi. 10.1007/s00204-010-0522-z
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- Article
The natural chemopreventive phytochemical R-sulforaphane is a far more potent inducer of the carcinogen-detoxifying enzyme systems in rat liver and lung than the S-isomer.
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- International Journal of Cancer, 2011, v. 128, n. 12, p. 2775, doi. 10.1002/ijc.25620
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- Article
Induction of Apoptosis and Cytotoxicity by Isothiocyanate Sulforaphene in Human Hepatocarcinoma HepG2 Cells.
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- Nutrients, 2018, v. 10, n. 6, p. 718, doi. 10.3390/nu10060718
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- Article
Contribution of CYP1A2 in the hepatic metabolism of melatonin: studies with isolated microsomal preparations and liver slices.
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- Journal of Pineal Research, 2001, v. 31, n. 4, p. 333, doi. 10.1034/j.1600-079X.2001.310408.x
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- Article
A Study of the Mutagenicity of Melatonin and 6-Hydroxymelatonin.
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- Journal of Pineal Research, 1989, v. 6, n. 1, p. 73, doi. 10.1111/j.1600-079X.1989.tb00404.x
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- Article
Differential response of four human livers to modulation of phase II enzyme systems by the chemopreventive phytochemical phenethyl isothiocyanate.
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- Molecular Nutrition & Food Research, 2010, v. 54, n. 10, p. 1477, doi. 10.1002/mnfr.200900598
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- Article
Repeated oral administration modulates the pharmacokinetic behavior of the chemopreventive agent phenethyl isothiocyanate in rats.
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- Molecular Nutrition & Food Research, 2010, v. 54, n. 3, p. 426, doi. 10.1002/mnfr.200900090
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- Article
The aliphatic isothiocyanates erucin and sulforaphane do not effectively up-regulate NAD(P)H:quinone oxidoreductase (NQO1) in human liver compared with rat.
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- Molecular Nutrition & Food Research, 2009, v. 53, n. 7, p. 836, doi. 10.1002/mnfr.200800292
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- Article
Effect of diet and nutrition on the expression of cytochromes P450.
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- Xenobiotica, 1999, v. 29, n. 2, p. 109, doi. 10.1080/004982599238704
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- Article
Interactions between polycyclic aromatic hydrocarbons in binary mixtures: Effects on gene expression and DNA adduct formation in precision-cut rat liver slices.
- Published in:
- Mutagenesis, 2008, v. 23, n. 6, p. 491, doi. 10.1093/mutage/gen041
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- Publication type:
- Article
Up-regulation of the glutathione S-transferase system in human liver by polycyclic aromatic hydrocarbons; comparison with rat liver and lung.
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- Mutagenesis, 2008, v. 23, n. 4, p. 299
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- Publication type:
- Article
Modulation of gene expression and DNA-adduct formation in precision-cut liver slices exposed to polycyclic aromatic hydrocarbons of different carcinogenic potency.
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- Mutagenesis, 2007, v. 22, n. 1, p. 55, doi. 10.1093/mutage/gel058
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- Publication type:
- Article
Black tea intake modulates the excretion of urinary mutagens in rats exposed to 6-aminochrysene: induction of cytochromes P450 by 6-aminochrysene in the rat.
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- Mutagenesis, 2005, v. 20, n. 1, p. 23, doi. 10.1093/mutage/gei002
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- Article
Effects of black tea theafulvins on aflatoxin B1 mutagenesis in the Ames test.
- Published in:
- Mutagenesis, 2003, v. 18, n. 2, p. 145, doi. 10.1093/mutage/18.2.145
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- Article
Isothiocyanates and Xenobiotic Detoxification.
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- Molecular Nutrition & Food Research, 2018, v. 62, n. 18, p. 1, doi. 10.1002/mnfr.201700916
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- Publication type:
- Article
Phenethyl isothiocyanate, a naturally occurring phytochemical, is an antagonist of the aryl hydrocarbon receptor.
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- Molecular Nutrition & Food Research, 2012, v. 56, n. 3, p. 425, doi. 10.1002/mnfr.201100548
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- Article