Works by Intagliata, Sebastiano

Results: 28

Discovery of 3‐(2‐aminoethyl)‐thiazolidine‐2,4‐diones as a novel chemotype of sigma‐1 receptor ligands.

Published in:

Chemical Biology & Drug Design, 2022, v. 100, n. 1, p. 25, doi. 10.1111/cbdd.14047

By:

Elkholy, Nada;
Abdelwaly, Ahmad;
Mohamed, Karim;
Amata, Emanuele;
Lombino, Jessica;
Cosentino, Giuseppe;
Intagliata, Sebastiano;
Helal, Mohamed A.

Publication type:

Article

Evaluation of the anticancer effects exerted by 5-fluorouracil and heme oxygenase-1 inhibitor hybrids in HTC116 colorectal cancer cells.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2024, v. 39, n. 1, p. 1, doi. 10.1080/14756366.2024.2337191

By:

Salerno, Loredana;
Notaro, Antonietta;
Consoli, Valeria;
Affranchi, Federica;
Pittalà, Valeria;
Sorrenti, Valeria;
Vanella, Luca;
Giuliano, Michela;
Intagliata, Sebastiano

Publication type:

Article

Novel mutual prodrug of 5-fluorouracil and heme oxygenase-1 inhibitor (5-FU/HO-1 hybrid): design and preliminary in vitro evaluation.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 1377, doi. 10.1080/14756366.2021.1928111

By:

Salerno, Loredana;
Vanella, Luca;
Sorrenti, Valeria;
Consoli, Valeria;
Ciaffaglione, Valeria;
Fallica, Antonino N.;
Canale, Vittorio;
Zajdel, Paweł;
Pignatello, Rosario;
Intagliata, Sebastiano

Publication type:

Article

Lauric acid-based thermosensitive delivery system for the treatment of head and neck squamous cell carcinoma.

Published in:

Journal of Drug Targeting, 2024, v. 32, n. 4, p. 433, doi. 10.1080/1061186X.2024.2323056

By:

Ali Alghamdi, Maha;
Haider, Mohamed;
Intagliata, Sebastiano;
Pittalà, Valeria;
Jagal, Jayalakshmi;
Haider, Youssef;
Althaf, Nasneen;
Greish, Khaled

Publication type:

Article

Solid Lipid Nanoparticles Loading Idebenone Ester with Pyroglutamic Acid: In Vitro Antioxidant Activity and In Vivo Topical Efficacy.

Published in:

Nanomaterials (2079-4991), 2019, v. 9, n. 1, p. 43, doi. 10.3390/nano9010043

By:

Montenegro, Lucia;
Panico, Anna Maria;
Santagati, Ludovica Maria;
Siciliano, Edy Angela;
Intagliata, Sebastiano;
Modica, Maria N.

Publication type:

Article

The analgesic potential of glycosides derived from medicinal plants.

Published in:

DARU: Journal of Pharmaceutical Sciences, 2020, v. 28, p. 387, doi. 10.1007/s40199-019-00319-7

By:

Khan, Haroon;
Pervaiz, Aini;
Intagliata, Sebastiano;
Das, Niranjan;
Nagulapalli Venkata, Kalyan C.;
Atanasov, Atanas G.;
Najda, Agnieszka;
Nabavi, Seyed Mohammad;
Wang, Dongdong;
Pittalà, Valeria;
Bishayee, Anupam

Publication type:

Article

Characterization of CM-398, a Novel Selective Sigma-2 Receptor Ligand, as a Potential Therapeutic for Neuropathic Pain.

Published in:

Molecules, 2022, v. 27, n. 11, p. 3617, doi. 10.3390/molecules27113617

By:

Wilson, Lisa L.;
Alleyne, Amy R.;
Eans, Shainnel O.;
Cirino, Thomas J.;
Stacy, Heather M.;
Mottinelli, Marco;
Intagliata, Sebastiano;
McCurdy, Christopher R.;
McLaughlin, Jay P.

Publication type:

Article

Novel Tyrosine Kinase Inhibitors to Target Chronic Myeloid Leukemia.

Published in:

Molecules, 2022, v. 27, n. 10, p. 3220, doi. 10.3390/molecules27103220

By:

Ciaffaglione, Valeria;
Consoli, Valeria;
Intagliata, Sebastiano;
Marrazzo, Agostino;
Romeo, Giuseppe;
Pittalà, Valeria;
Greish, Khaled;
Vanella, Luca;
Floresta, Giuseppe;
Rescifina, Antonio;
Salerno, Loredana;
Sorrenti, Valeria

Publication type:

Article

Lipid Nanoparticles Traverse Non-Corneal Path to Reach the Posterior Eye Segment: In Vivo Evidence.

Published in:

Molecules, 2021, v. 26, n. 15, p. 4673, doi. 10.3390/molecules26154673

By:

Puglia, Carmelo;
Santonocito, Debora;
Romeo, Giuseppe;
Intagliata, Sebastiano;
Romano, Giovanni Luca;
Strettoi, Enrica;
Novelli, Elena;
Ostacolo, Carmine;
Campiglia, Pietro;
Sommella, Eduardo Maria;
Pignatello, Rosario;
Bucolo, Claudio

Publication type:

Article

Combination of Heme Oxygenase-1 Inhibition and Sigma Receptor Modulation for Anticancer Activity.

Published in:

Molecules, 2021, v. 26, n. 13, p. 3860, doi. 10.3390/molecules26133860

By:

Romeo, Giuseppe;
Ciaffaglione, Valeria;
Amata, Emanuele;
Dichiara, Maria;
Calabrese, Loredana;
Vanella, Luca;
Sorrenti, Valeria;
Grosso, Salvo;
D'Amico, Agata Grazia;
D'Agata, Velia;
Intagliata, Sebastiano;
Salerno, Loredana

Publication type:

Article

Design, Synthesis, and Antitumor Activity of Olmutinib Derivatives Containing Acrylamide Moiety.

Published in:

Molecules, 2021, v. 26, n. 10, p. 3041, doi. 10.3390/molecules26103041

By:

Hu, Xiaohan;
Tang, Sheng;
Yang, Feiyi;
Zheng, Pengwu;
Xu, Shan;
Pan, Qingshan;
Zhu, Wufu;
Salerno, Loredana;
Intagliata, Sebastiano

Publication type:

Article

Photocytotoxic Activity of Ruthenium(II) Complexes with Phenanthroline-Hydrazone Ligands.

Published in:

Molecules, 2021, v. 26, n. 7, p. 2084, doi. 10.3390/molecules26072084

By:

Silva-Caldeira, Priscila Pereira;
Oliveira Junior, Antônio Carlos Almendagna de;
Pereira-Maia, Elene Cristina;
Salerno, Loredana;
Intagliata, Sebastiano

Publication type:

Article

Synthesis and Molecular Modelling Studies of New 1,3-Diaryl-5-Oxo-Proline Derivatives as Endothelin Receptor Ligands.

Published in:

Molecules, 2020, v. 25, n. 8, p. 1851, doi. 10.3390/molecules25081851

By:

Intagliata, Sebastiano;
Helal, Mohamed A.;
Materia, Luisa;
Pittalà, Valeria;
Salerno, Loredana;
Marrazzo, Agostino;
Cagnotto, Alfredo;
Salmona, Mario;
Modica, Maria N.;
Romeo, Giuseppe

Publication type:

Article

Discovery of a Highly Selective Sigma-2 Receptor Ligand, 1-(4-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)butyl)-3-methyl-1H-benzo[d]imidazol-2(3H)-one (CM398), with Drug-Like Properties and Antinociceptive Effects In Vivo.

Published in:

AAPS Journal, 2020, v. 22, n. 5, p. N.PAG, doi. 10.1208/s12248-020-00472-x

By:

Intagliata, Sebastiano;
Sharma, Abhisheak;
King, Tamara I.;
Mesangeau, Christophe;
Seminerio, Michael;
Chin, Frederick T.;
Wilson, Lisa L.;
Matsumoto, Rae R.;
McLaughlin, Jay P.;
Avery, Bonnie A.;
McCurdy, Christopher R.

Publication type:

Article

A computer-aided approach to identify novel Leishmania major protein disulfide isomerase inhibitors for treatment of leishmaniasis.

Published in:

Journal of Computer-Aided Molecular Design, 2021, v. 35, n. 3, p. 297, doi. 10.1007/s10822-021-00374-w

By:

Ben Khalaf, Noureddine;
Pham, Susie;
Romeo, Giuseppe;
Abdelghany, Sara;
Intagliata, Sebastiano;
Sedillo, Peter;
Salerno, Loredana;
Gonzales, Jessica;
Fathallah, Dahmani M.;
Perkins, Douglas J.;
Hurwitz, Ivy;
Pittalà, Valeria

Publication type:

Article

Characterization of Sigma 1 Receptor Antagonist CM-304 and Its Analog, AZ-66: Novel Therapeutics Against Allodynia and Induced Pain.

Published in:

Frontiers in Pharmacology, 2019, p. N.PAG, doi. 10.3389/fphar.2019.00678

By:

Cirino, Thomas J.;
Eans, Shainnel O.;
Medina, Jessica M.;
Wilson, Lisa L.;
Mottinelli, Marco;
Intagliata, Sebastiano;
McCurdy, Christopher R.;
McLaughlin, Jay P.

Publication type:

Article

Heme Oxygenase Modulation Drives Ferroptosis in TNBC Cells.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 10, p. 5709, doi. 10.3390/ijms23105709

By:

Consoli, Valeria;
Sorrenti, Valeria;
Pittalà, Valeria;
Greish, Khaled;
D'Amico, Agata Grazia;
Romeo, Giuseppe;
Intagliata, Sebastiano;
Salerno, Loredana;
Vanella, Luca

Publication type:

Article

Examination of the Novel Sigma-1 Receptor Antagonist, SI 1/28, for Antinociceptive and Anti-allodynic Efficacy against Multiple Types of Nociception with Fewer Liabilities of Use.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 2, p. 615, doi. 10.3390/ijms23020615

By:

Wilson, Lisa L.;
Eans, Shainnel O.;
Ramadan-Siraj, Insitar;
Modica, Maria N.;
Romeo, Giuseppe;
Intagliata, Sebastiano;
McLaughlin, Jay P.

Publication type:

Article

New Arylethanolimidazole Derivatives as HO-1 Inhibitors with Cytotoxicity against MCF-7 Breast Cancer Cells.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 6, p. 1923, doi. 10.3390/ijms21061923

By:

Ciaffaglione, Valeria;
Intagliata, Sebastiano;
Pittalà, Valeria;
Marrazzo, Agostino;
Sorrenti, Valeria;
Vanella, Luca;
Rescifina, Antonio;
Floresta, Giuseppe;
Sultan, Ameera;
Greish, Khaled;
Salerno, Loredana

Publication type:

Article

Protective Effects of Caffeic Acid Phenethyl Ester (CAPE) and Novel Cape Analogue as Inducers of Heme Oxygenase-1 in Streptozotocin-Induced Type 1 Diabetic Rats.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 10, p. 2441, doi. 10.3390/ijms20102441

By:

Sorrenti, Valeria;
Raffaele, Marco;
Vanella, Luca;
Acquaviva, Rosaria;
Salerno, Loredana;
Pittalà, Valeria;
Intagliata, Sebastiano;
Di Giacomo, Claudia

Publication type:

Article

Novel Structural Insight into Inhibitors of Heme Oxygenase-1 (HO-1) by New Imidazole-Based Compounds: Biochemical and In Vitro Anticancer Activity Evaluation.

Published in:

Molecules, 2018, v. 23, n. 5, p. 1209, doi. 10.3390/molecules23051209

By:

Greish, Khaled F.;
Salerno, Loredana;
Al Zahrani, Reem;
Amata, Emanuele;
Modica, Maria N.;
Romeo, Giuseppe;
Marrazzo, Agostino;
Prezzavento, Orazio;
Sorrenti, Valeria;
Rescifina, Antonio;
Floresta, Giuseppe;
Intagliata, Sebastiano;
Pittalà, Valeria

Publication type:

Article

In vitro and in silico analysis of imatinib analogues as anti- Trypanosoma cruzi drug candidates.

Published in:

Parasitology, 2023, v. 150, n. 4, p. 359, doi. 10.1017/S0031182023000057

By:

Nesic de Freitas, Luca S. F.;
da Silva, Cristiane França;
Intagliata, Sebastiano;
Amata, Emanuele;
Salerno, Loredana;
Soeiro, Maria de Nazaré Correia

Publication type:

Article

The Inhibition of Neuropathic Pain Incited by Nerve Injury and Accompanying Mood Disorders by New Heme Oxygenase-1 Inducers: Mechanisms Implicated.

Published in:

Antioxidants, 2023, v. 12, n. 10, p. 1859, doi. 10.3390/antiox12101859

By:

Suárez-Rojas, Irene;
Pérez-Fernández, Montse;
Bai, Xue;
Martínez-Martel, Ignacio;
Intagliata, Sebastiano;
Pittalà, Valeria;
Salerno, Loredana;
Pol, Olga

Publication type:

Article

Glucose-Impaired Corneal Re-Epithelialization Is Promoted by a Novel Derivate of Dimethyl Fumarate.

Published in:

Antioxidants, 2021, v. 10, n. 6, p. 831, doi. 10.3390/antiox10060831

By:

Giurdanella, Giovanni;
Longo, Anna;
Salerno, Loredana;
Romeo, Giuseppe;
Intagliata, Sebastiano;
Lupo, Gabriella;
Distefano, Alfio;
Platania, Chiara Bianca Maria;
Bucolo, Claudio;
Li Volti, Giovanni;
Anfuso, Carmelina Daniela;
Pittalà, Valeria

Publication type:

Article

In Vitro Antioxidant and Anti-Glycation Activity of Resveratrol and Its Novel Triester with Trolox.

Published in:

Antioxidants, 2021, v. 10, n. 1, p. 12, doi. 10.3390/antiox10010012

By:

Intagliata, Sebastiano;
Spadaro, Angelo;
Lorenti, Miriam;
Panico, Annamaria;
Siciliano, Edy A.;
Barbagallo, Sabrina;
Macaluso, Benito;
Kamble, Shyam H.;
Modica, Maria N.;
Montenegro, Lucia

Publication type:

Article

Strategies to Improve Resveratrol Systemic and Topical Bioavailability: An Update.

Published in:

Antioxidants, 2019, v. 8, n. 8, p. 244, doi. 10.3390/antiox8080244

By:

Intagliata, Sebastiano;
Modica, Maria N.;
Santagati, Ludovica M.;
Montenegro, Lucia

Publication type:

Article

Discovery of SI 1/20 and SI 1/22 as Mutual Prodrugs of 5‐Fluorouracil and Imidazole‐Based Heme Oxygenase 1 Inhibitor with Improved Cytotoxicity in DU145 Prostate Cancer Cells.

Published in:

ChemMedChem, 2023, v. 18, n. 8, p. 1, doi. 10.1002/cmdc.202300047

By:

Salerno, Loredana;
Sorrenti, Valeria;
Pittalà, Valeria;
Consoli, Valeria;
Modica, Maria N.;
Romeo, Giuseppe;
Marrazzo, Agostino;
Giuliano, Michela;
Zajdel, Paweł;
Vanella, Luca;
Intagliata, Sebastiano

Publication type:

Article

Mutual Prodrugs of 5‐Fluorouracil: From a Classic Chemotherapeutic Agent to Novel Potential Anticancer Drugs.

Published in:

ChemMedChem, 2021, v. 16, n. 23, p. 3496, doi. 10.1002/cmdc.202100473

By:

Ciaffaglione, Valeria;
Modica, Maria N.;
Pittalà, Valeria;
Romeo, Giuseppe;
Salerno, Loredana;
Intagliata, Sebastiano

Publication type:

Article