Found: 36
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Comprehensive characterization of human brain‐derived extracellular vesicles using multiple isolation methods: Implications for diagnostic and therapeutic applications.
- Published in:
- Journal of Extracellular Vesicles, 2023, v. 12, n. 8, p. 1, doi. 10.1002/jev2.12358
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- Publication type:
- Article
Alzheimer's disease brain-derived extracellular vesicles spread tau pathology in interneurons.
- Published in:
- 2021
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- Publication type:
- journal article
The systemic disruption of P2rx7 alleviates tau pathology in P301S tau mice via inhibition of extracellular vesicle release.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.064257
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- Publication type:
- Article
Alzheimer's disease associated AKAP9 I2558M mutation alters posttranslational modification and interactome of tau and cellular functions in CRISPR‐edited human neuronal cells.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.058592
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- Publication type:
- Article
Evaluation of extracellular vesicles isolated from the cerebrospinal fluid and plasma from former National Football League players at risk for chronic traumatic encephalopathy: Biomarkers (non‐neuroimaging) / plasma/serum/urine biomarkers.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.042233
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- Publication type:
- Article
Assessment of a novel tau propagation pathway from layer II medial entorhinal cortical neurons to CA1 pyramidal neurons as an early BRAAK stage mouse model: Development of new models and analysis methods: Multisystem platform models of ADRD.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.042179
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- Publication type:
- Article
CSF1R inhibitor abrogates tau propagation exacerbated in APP<sup>NL‐G‐F</sup> knock‐in mice but enhances fibrillar beta‐amyloidosis and dystrophic neurite formation in the brain: Development of new models and analysis methods/neuroinflammation
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.040958
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- Publication type:
- Article
Elucidating the pathogenic mechanisms of AD brain‐derived, tau‐containing extracellular vesicles: Highly transmissible and preferential propagation to GABAergic neurons: EV or not EV? Extracellular propagation of AD pathogenic molecules and evaluation of brain cell‐derived extracellular vesicles from patient plasma as EV biomarkers
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.037316
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- Publication type:
- Article
Proteomic and biological profiling of extracellular vesicles from Alzheimer's disease human brain tissues.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 6, p. 896, doi. 10.1002/alz.12089
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- Publication type:
- Article
P4‐149: P2RX7 INHIBITOR SUPPRESSES EXOSOME SECRETION, DELAYS PROTEOPATHIC TAU ACCUMULATION AND MEMORY IMPAIRMENT IN PS19 P301S TAU MICE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1331, doi. 10.1016/j.jalz.2019.06.3810
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- Publication type:
- Article
P3‐089: PROTEOMIC PROFILING OF EXTRACELLULAR VESICLES DERIVED FROM CEREBROSPINAL FLUID OF ALZHEIMER'S DISEASE AND MILD COGNITIVE IMPAIRMENTS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P959, doi. 10.1016/j.jalz.2019.06.3116
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- Publication type:
- Article
O1‐01‐04: IDENTIFICATION AND BIOLOGICAL CHARACTERIZATION OF EXTRACELLULAR VESICLE PROTEINS FOR PROPAGATION AND SPREAD OF TAU.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P192, doi. 10.1016/j.jalz.2019.06.4520
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- Publication type:
- Article
O2‐01‐02: CHARACTERIZATION OF HUMAN ALZHEIMER'S DISEASE BRAIN‐DERIVED EXOSOMES.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P608, doi. 10.1016/j.jalz.2018.06.2640
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- Publication type:
- Article
P1‐025: EXOSOMES CONTAINING SPECIFIC TAU OLIGOMER FORMATIONS ACCELERATE PATHOLOGICAL TAU PHOSPHORYLATION IN C57BL/6 MICE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P275, doi. 10.1016/j.jalz.2018.06.026
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- Publication type:
- Article
COMPREHENSIVE CHARACTERIZATION OF HUMAN ALZHEIMER’S DISEASE BRAIN-DERIVED EXOSOMES.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P907, doi. 10.1016/j.jalz.2017.07.323
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- Publication type:
- Article
MICROGLIAL EXOSOMES PROPAGATE TAU PROTEIN FROM THE ENTORHINAL CORTEX TO THE HIPPOCAMPUS: AN EARLY PATHOPHYSIOLOGY OF ALZHEIMER’S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P339, doi. 10.1016/j.jalz.2016.06.624
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- Publication type:
- Article
Phosphorylation of collapsin response mediator protein-2 and axonal degeneration in transgenic mice expressing a familial Alzheimer's disease mutant of APP and tau-tubulin kinase 1
- Published in:
- 2012
- By:
- Publication type:
- Abstract
Accelerated neurodegeneration and phenotypic switch of neuroinflammation in transgenic mice expressing P301L tau-mutant and tau-tubulin kinase 1
- Published in:
- 2012
- By:
- Publication type:
- Abstract
Tau-tubulin kinase 1 and amyloid-β peptide induce phosphorylation of collapsin response mediator protein-2 and enhance neurite degeneration in Alzheimer disease mouse models.
- Published in:
- Acta Neuropathologica Communications, 2020, v. 8, n. 1, p. 1, doi. 10.1186/s40478-020-0890-4
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- Publication type:
- Article
Antisense oligonucleotide-based targeting of Tau-tubulin kinase 1 prevents hippocampal accumulation of phosphorylated tau in PS19 tauopathy mice.
- Published in:
- Acta Neuropathologica Communications, 2023, v. 11, n. 1, p. 1, doi. 10.1186/s40478-023-01661-3
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- Publication type:
- Article
Regulating microglial miR-155 transcriptional phenotype alleviates Alzheimer's-induced retinal vasculopathy by limiting Clec7a/Galectin-3<sup>+</sup> neurodegenerative microglia.
- Published in:
- Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01439-z
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- Publication type:
- Article
Comparison of nanoimaging and nanoflow based detection of extracellular vesicles at a single particle resolution.
- Published in:
- Journal of Extracellular Biology, 2024, v. 3, n. 10, p. 1, doi. 10.1002/jex2.70016
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- Publication type:
- Article
P2RX7 plays a critical role in extracellular vesicle‐mediated secretion of pathogenic molecules from microglia and astrocytes.
- Published in:
- Journal of Extracellular Biology, 2024, v. 3, n. 7, p. 1, doi. 10.1002/jex2.155
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- Publication type:
- Article
Proteomic Profiling of Extracellular Vesicles Derived from Cerebrospinal Fluid of Alzheimer's Disease Patients: A Pilot Study.
- Published in:
- Cells (2073-4409), 2020, v. 9, n. 9, p. 1959, doi. 10.3390/cells9091959
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- Publication type:
- Article
Depletion of microglia and inhibition of exosome synthesis halt tau propagation.
- Published in:
- Nature Neuroscience, 2015, v. 18, n. 11, p. 1584, doi. 10.1038/nn.4132
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- Publication type:
- Article
Enrichment of Phosphorylated Tau (Thr181) and Functionally Interacting Molecules in Chronic Traumatic Encephalopathy Brain-derived Extracellular Vesicles.
- Published in:
- Aging & Disease, 2021, v. 12, n. 6, p. 1376, doi. 10.14336/AD.2020.1007
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- Publication type:
- Article
Proteomic Profiling of Extracellular Vesicles Separated from Plasma of Former National Football League Players at Risk for Chronic Traumatic Encephalopathy.
- Published in:
- Aging & Disease, 2021, v. 12, n. 6, p. 1363, doi. 10.14336/AD.2020.0908
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- Publication type:
- Article
Proteomic Profiling of Extracellular Vesicles Isolated From Cerebrospinal Fluid of Former National Football League Players at Risk for Chronic Traumatic Encephalopathy.
- Published in:
- Frontiers in Neuroscience, 2019, p. 1, doi. 10.3389/fnins.2019.01059
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- Publication type:
- Article
Wolframin-1–expressing neurons in the entorhinal cortex propagate tau to CA1 neurons and impair hippocampal memory in mice.
- Published in:
- Science Translational Medicine, 2021, v. 13, n. 611, p. 1, doi. 10.1126/scitranslmed.abe8455
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- Publication type:
- Article
Tau-tubulin kinase.
- Published in:
- Frontiers in Molecular Neuroscience, 2014, v. 7, p. 1, doi. 10.3389/fnmol.2014.00033
- By:
- Publication type:
- Article
Alzheimer's disease associated AKAP9 I2558M mutation alters posttranslational modification and interactome of tau and cellular functions in CRISPR‐edited human neuronal cells.
- Published in:
- Aging Cell, 2022, v. 21, n. 6, p. 1, doi. 10.1111/acel.13617
- By:
- Publication type:
- Article
Plaque associated microglia hyper-secrete extracellular vesicles and accelerate tau propagation in a humanized APP mouse model.
- Published in:
- Molecular Neurodegeneration, 2021, v. 16, n. 1, p. 1, doi. 10.1186/s13024-021-00440-9
- By:
- Publication type:
- Article
Correction to: Plaque associated microglia hyper-secrete extracellular vesicles and accelerate tau propagation in a humanized APP mouse model.
- Published in:
- 2021
- By:
- Publication type:
- Correction Notice
Plaque associated microglia hyper-secrete extracellular vesicles and accelerate tau propagation in a humanized APP mouse model.
- Published in:
- Molecular Neurodegeneration, 2021, v. 16, n. 1, p. 1, doi. 10.1186/s13024-021-00440-9
- By:
- Publication type:
- Article
P2RX7 inhibitor suppresses exosome secretion and disease phenotype in P301S tau transgenic mice.
- Published in:
- Molecular Neurodegeneration, 2020, v. 15, n. 1, p. N.PAG, doi. 10.1186/s13024-020-00396-2
- By:
- Publication type:
- Article
miR-155 Is Essential for Inflammation-Induced Hippocampal Neurogenic Dysfunction.
- Published in:
- Journal of Neuroscience, 2015, v. 35, n. 26, p. 9764, doi. 10.1523/JNEUROSCI.4790-14.2015
- By:
- Publication type:
- Article