Works by Ikeuchi, Takeshi

Results: 190

A novel frameshift GRN mutation results in frontotemporal lobar degeneration with a distinct clinical phenotype in two siblings: case report and literature review.

Published in:

2017

By:

Takashi Hosaka;
Kazuhiro Ishii;
Takeshi Miura;
Naomi Mezaki;
Kensaku Kasuga;
Takeshi Ikeuchi;
Akira Tamaoka;
Hosaka, Takashi;
Ishii, Kazuhiro;
Miura, Takeshi;
Mezaki, Naomi;
Kasuga, Kensaku;
Ikeuchi, Takeshi;
Tamaoka, Akira

Publication type:

journal article

Distinct patterns of cognitive traits in extreme old age and Alzheimer's disease.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2025, v. 21, n. 4, p. 1, doi. 10.1002/alz.70155

By:

Nishimoto, Yoshinori;
Sasaki, Takashi;
Abe, Yukiko;
Hara, Norikazu;
Miyashita, Akinori;
Konishi, Mika;
Eguchi, Yoko;
Ito, Daisuke;
Hirose, Nobuyoshi;
Mimura, Masaru;
Ikeuchi, Takeshi;
Okano, Hideyuki;
Arai, Yasumichi

Publication type:

Article

Early increase of the synaptic blood marker β‐synuclein in asymptomatic autosomal dominant Alzheimer's disease.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2025, v. 21, n. 4, p. 1, doi. 10.1002/alz.70146

By:

Oeckl, Patrick;
Mayer, Benjamin;
Bateman, Randall J.;
Day, Gregory S.;
Fox, Nick C.;
Huey, Edward D.;
Ibanez, Laura;
Ikeuchi, Takeshi;
Jucker, Mathias;
Lee, Jae‐Hong;
Levin, Johannes;
Llibre‐Guerra, Jorge J.;
Lopera, Francisco;
McDade, Eric;
Morris, John C.;
Niimi, Yoshiki;
Roh, Jee Hoon;
Sánchez‐Valle, Raquel;
Schofield, Peter R.;
Otto, Markus

Publication type:

Article

Initial symptoms of early‐onset dementia in Japan: nationwide survey.

Published in:

Psychogeriatrics, 2023, v. 23, n. 3, p. 422, doi. 10.1111/psyg.12949

By:

Edahiro, Ayako;
Okamura, Tsuyoshi;
Arai, Tetsuaki;
Ikeuchi, Takeshi;
Ikeda, Manabu;
Utsumi, Kumiko;
Ota, Hidetaka;
Kakuma, Tatsuyuki;
Kawakatsu, Shinobu;
Konagaya, Yoko;
Suzuki, Kyoko;
Tanimukai, Satoshi;
Miyanaga, Kazuo;
Awata, Shuichi

Publication type:

Article

Involvement of inflammation in the medial temporal region in the development of agitation in Alzheimer's disease: an in vivo positron emission tomography study.

Published in:

Psychogeriatrics, 2023, v. 23, n. 1, p. 126, doi. 10.1111/psyg.12915

By:

Yasuno, Fumihiko;
Kimura, Yasuyuki;
Ogata, Aya;
Ikenuma, Hiroshi;
Abe, Junichiro;
Minami, Hiroyuki;
Nihashi, Takashi;
Yokoi, Kastunori;
Hattori, Saori;
Shimoda, Nobuyoshi;
Watanabe, Atsushi;
Kasuga, Kensaku;
Ikeuchi, Takeshi;
Takeda, Akinori;
Sakurai, Takashi;
Ito, Kengo;
Kato, Takashi

Publication type:

Article

Prevalence and subtype distribution of early‐onset dementia in Japan.

Published in:

Psychogeriatrics, 2020, v. 20, n. 6, p. 817, doi. 10.1111/psyg.12596

By:

Awata, Shuichi;
Edahiro, Ayako;
Arai, Tetsuaki;
Ikeda, Manabu;
Ikeuchi, Takeshi;
Kawakatsu, Shinobu;
Konagaya, Yoko;
Miyanaga, Kazuo;
Ota, Hidetaka;
Suzuki, Kyoko;
Tanimukai, Satoshi;
Utsumi, Kumiko;
Kakuma, Tatsuyuki

Publication type:

Article

Remarkable behavioural signs and progressive non‐fluent aphasia in a patient with adult‐onset leucoencephalopathy with axonal spheroids and pigmented glia.

Published in:

2019

By:

Funayama, Michitaka;
Sugihara, Masako;
Takata, Taketo;
Mimura, Masaru;
Ikeuchi, Takeshi

Publication type:

Case Study

Clinical course of pathologically confirmed corticobasal degeneration and corticobasal syndrome.

Published in:

Brain Communications, 2023, v. 5, n. 6, p. 1, doi. 10.1093/braincomms/fcad296

By:

Ikuko Aiba;
Yuichi Hayashi;
Takayoshi Shimohata;
Mari Yoshida;
Yuko Saito;
Koichi Wakabayashi;
Takashi Komori;
Masato Hasegawa;
Takeshi Ikeuchi;
Tokumaru, Aya M.;
Keita Sakurai;
Shigeo Murayama;
Kazuko Hasegawa;
Toshiki Uchihara;
Yasuko Toyoshima;
Yufuko Saito;
Ichiro Yabe;
Satoshi Tanikawa;
Keizo Sugaya;
Kentaro Hayashi

Publication type:

Article

Serum microRNA miR-501-3p as a potential biomarker related to the progression of Alzheimer's disease.

Published in:

Acta Neuropathologica Communications, 2017, v. 5, p. 1, doi. 10.1186/s40478-017-0414-z

By:

Norikazu Hara;
Masataka Kikuchi;
Akinori Miyashita;
Hiroyuki Hatsuta;
Yuko Saito;
Kensaku Kasuga;
Shigeo Murayama;
Takeshi Ikeuchi;
Ryozo Kuwano

Publication type:

Article

Switched Aβ43 generation in familial Alzheimer's disease with presenilin 1 mutation.

Published in:

Translational Psychiatry, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41398-021-01684-1

By:

Kakuda, Nobuto;
Takami, Mako;
Okochi, Masayasu;
Kasuga, Kensaku;
Ihara, Yasuo;
Ikeuchi, Takeshi

Publication type:

Article

Ethnic and trans-ethnic genome-wide association studies identify new loci influencing Japanese Alzheimer's disease risk.

Published in:

Translational Psychiatry, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41398-021-01272-3

By:

Shigemizu, Daichi;
Mitsumori, Risa;
Akiyama, Shintaro;
Miyashita, Akinori;
Morizono, Takashi;
Higaki, Sayuri;
Asanomi, Yuya;
Hara, Norikazu;
Tamiya, Gen;
Kinoshita, Kengo;
Ikeuchi, Takeshi;
Niida, Shumpei;
Ozaki, Kouichi

Publication type:

Article

Ethnic and trans-ethnic genome-wide association studies identify new loci influencing Japanese Alzheimer's disease risk.

Published in:

Translational Psychiatry, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41398-021-01272-3

By:

Shigemizu, Daichi;
Mitsumori, Risa;
Akiyama, Shintaro;
Miyashita, Akinori;
Morizono, Takashi;
Higaki, Sayuri;
Asanomi, Yuya;
Hara, Norikazu;
Tamiya, Gen;
Kinoshita, Kengo;
Ikeuchi, Takeshi;
Niida, Shumpei;
Ozaki, Kouichi

Publication type:

Article

Switched Aβ43 generation in familial Alzheimer's disease with presenilin 1 mutation.

Published in:

Translational Psychiatry, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41398-021-01684-1

By:

Kakuda, Nobuto;
Takami, Mako;
Okochi, Masayasu;
Kasuga, Kensaku;
Ihara, Yasuo;
Ikeuchi, Takeshi

Publication type:

Article

Ethnic and trans-ethnic genome-wide association studies identify new loci influencing Japanese Alzheimer's disease risk.

Published in:

Translational Psychiatry, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41398-021-01272-3

By:

Shigemizu, Daichi;
Mitsumori, Risa;
Akiyama, Shintaro;
Miyashita, Akinori;
Morizono, Takashi;
Higaki, Sayuri;
Asanomi, Yuya;
Hara, Norikazu;
Tamiya, Gen;
Kinoshita, Kengo;
Ikeuchi, Takeshi;
Niida, Shumpei;
Ozaki, Kouichi

Publication type:

Article

Higher longitudinal brain white matter atrophy rate in aquaporin-4 IgG-positive NMOSD compared with healthy controls.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-38893-1

By:

Masuda, Hiroki;
Mori, Masahiro;
Hirano, Shigeki;
Uzawa, Akiyuki;
Uchida, Tomohiko;
Muto, Mayumi;
Ohtani, Ryohei;
Aoki, Reiji;
Hirano, Yoshiyuki;
Iwatsubo, Takeshi;
Asada, Takashi;
Arai, Hiroyuki;
Sugishita, Morihiro;
Matsuda, Hiroshi;
Ito, Kengo;
Senda, Michio;
Ishii, Kenji;
Kuwano, Ryozo;
Ikeuchi, Takeshi;
Sato, Noriko

Publication type:

Article

Higher longitudinal brain white matter atrophy rate in aquaporin-4 IgG-positive NMOSD compared with healthy controls.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-38893-1

By:

Masuda, Hiroki;
Mori, Masahiro;
Hirano, Shigeki;
Uzawa, Akiyuki;
Uchida, Tomohiko;
Muto, Mayumi;
Ohtani, Ryohei;
Aoki, Reiji;
Hirano, Yoshiyuki;
Japanese Alzheimer's Disease Neuroimaging Initiative (J-ADNI);
Iwatsubo, Takeshi;
Asada, Takashi;
Arai, Hiroyuki;
Sugishita, Morihiro;
Matsuda, Hiroshi;
Ito, Kengo;
Senda, Michio;
Ishii, Kenji;
Kuwano, Ryozo;
Ikeuchi, Takeshi

Publication type:

Article

Four Swedish cases of CSF1R‐related leukoencephalopathy: Visualization of clinical phenotypes.

Published in:

Acta Neurologica Scandinavica, 2022, v. 145, n. 5, p. 599, doi. 10.1111/ane.13589

By:

Rosenstein, Igal;
Andersen, Oluf;
Victor, Daniel;
Englund, Elisabet;
Granberg, Tobias;
Hedberg‐Oldfors, Carola;
Jood, Katarina;
Fitrah, Yusran Ady;
Ikeuchi, Takeshi;
Danylaité Karrenbauer, Virginija

Publication type:

Article

Cell-free generation of the Notch1 intracellular domain (NICD) and APP-CTFγ.

Published in:

NeuroMolecular Medicine, 2002, v. 1, n. 1, p. 43, doi. 10.1385/NMM:1:1:43

By:

Ikeuchi, Takeshi;
Sisodia, Sangram

Publication type:

Article

Pathological and Clinical Spectrum of Progressive Supranuclear Palsy: With Special Reference to Astrocytic Tau Pathology.

Published in:

Brain Pathology, 2016, v. 26, n. 2, p. 155, doi. 10.1111/bpa.12265

By:

Yokoyama, Yuichi;
Toyoshima, Yasuko;
Shiga, Atsushi;
Tada, Mari;
Kitamura, Hideaki;
Hasegawa, Kazuko;
Onodera, Osamu;
Ikeuchi, Takeshi;
Someya, Toshiyuki;
Nishizawa, Masatoyo;
Kakita, Akiyoshi;
Takahashi, Hitoshi

Publication type:

Article

Globular Glial Mixed Four Repeat Tau and TDP-43 Proteinopathy with Motor Neuron Disease and Frontotemporal Dementia.

Published in:

Brain Pathology, 2016, v. 26, n. 1, p. 82, doi. 10.1111/bpa.12262

By:

Takeuchi, Ryoko;
Toyoshima, Yasuko;
Tada, Mari;
Tanaka, Hidetomo;
Shimizu, Hiroshi;
Shiga, Atsushi;
Miura, Takeshi;
Aoki, Kenju;
Aikawa, Akane;
Ishizawa, Shin;
Ikeuchi, Takeshi;
Nishizawa, Masatoyo;
Kakita, Akiyoshi;
Takahashi, Hitoshi

Publication type:

Article

Change in Cerebrospinal Fluid Tau Microtubule Binding Region Detects Symptom Onset, Cognitive Decline, Tangles, and Atrophy in Dominantly Inherited Alzheimer's Disease.

Published in:

Annals of Neurology, 2023, v. 93, n. 6, p. 1158, doi. 10.1002/ana.26620

By:

Horie, Kanta;
Li, Yan;
Barthélemy, Nicolas R.;
Gordon, Brian;
Hassenstab, Jason;
Benzinger, Tammie L.S.;
Fagan, Anne M.;
Morris, John C.;
Karch, Celeste M.;
Xiong, Chengjie;
Allegri, Ricardo;
Mendez, Patricio Chrem;
Ikeuchi, Takeshi;
Kasuga, Kensaku;
Noble, James;
Farlow, Martin;
Chhatwal, Jasmeer;
Day, Gregory;
Schofield, Peter R.;
Masters, Colin L.

Publication type:

Article

Impaired insulin signal transduction in neurons may be involved in β-amyloid-induced hyperphosphorylation of tau

Published in:

2011

By:

Tokutake, Takayoshi;
Kasuga, Kensaku;
Yajima, Ryuji;
Nishizawa, Masatoyo;
Ikeuchi, Takeshi

Publication type:

Abstract

Analysis of an Aβ-like peptide in CSF to reveal whether and how the cleavage precision of presenilin/γ-secretase is altered in AD patients

Published in:

2009

By:

Tagami, Shinji;
Okochi, Masayasu;
Yanagida, Kanta;
Nakayama, Taisuke;
Kodama, Takashi;
Nishitomi, Kouhei;
Tatsumi, Shin-Ichi;
Arai, Tetsuaki;
Ikeuchi, Takeshi;
Kasuga, Kensaku;
Ikeda, Masaki;
Deguchi, Kentaro;
Kazui, Hiroaki;
Morihara, Takashi;
Tanaka, Toshihisa;
Kudo, Takashi;
Tsuchiya, Kuniaki;
Akiyama, Haruhiko;
Kuwano, Ryozou;
Takeda, Masatoshi

Publication type:

Abstract

O4-03-01: Evidence that RER1 is the limiting cellular factor for the ER retrieval of gamma-secretase complex

Published in:

2008

By:

Kim, Seong-Hun;
Park, Hyo-Jin;
Ikeuchi, Takeshi;
Sisodia, Sangram S.

Publication type:

Abstract

Black rice bran intake reduces phosphorylated tau levels and enhances insulin signaling in the brain of aged normal mice.

Published in:

Bioscience, Biotechnology & Biochemistry, 2022, v. 86, n. 11, p. 1570, doi. 10.1093/bbb/zbac125

By:

Takashi Hara;
Hanae Toyama;
Yumi Ohata;
Takeshi Ikeuchi;
Sumiko Nakamura;
Toshio Joh;
Ken'ichi Ohtsubo

Publication type:

Article

Effects of super-hard rice bread blended with black rice bran on amyloid β peptide production and abrupt increase in postprandial blood glucose levels in mice.

Published in:

Bioscience, Biotechnology & Biochemistry, 2017, v. 81, n. 2, p. 323, doi. 10.1080/09168451.2016.1240605

By:

Nakamura, Sumiko;
Hara, Takashi;
Joh, Toshio;
Kobayashi, Atsushi;
Yamazaki, Akira;
Kasuga, Kensaku;
Ikeuchi, Takeshi;
Ohtsubo, Ken'ichi

Publication type:

Article

Low serum 25-hydroxyvitamin D increases cognitive impairment in elderly people.

Published in:

2019

By:

Sakuma, Mayumi;
Kitamura, Kaori;
Endo, Naoto;
Ikeuchi, Takeshi;
Yokoseki, Akio;
Onodera, Osamu;
Oinuma, Takeo;
Momotsu, Takeshi;
Sato, Kenji;
Nakamura, Kazutoshi;
Narita, Ichiei

Publication type:

journal article

Cerebral Braak stage and amygdala granular fuzzy astrocyte status have independent effects on neuronal 3R-tau and 4R-tau accumulations in the olfactory bulb, respectively, in cases with low to intermediate AD neuropathologic change.

Published in:

2025

By:

Yokota, Osamu;
Miki, Tomoko;
Nakashima-Yasuda, Hanae;
Ishizu, Hideki;
Haraguchi, Takashi;
Miyashita, Akinori;
Ikeuchi, Takeshi;
Hasegawa, Masato;
Nishikawa, Naoto;
Takenoshita, Shintaro;
Terada, Seishi;
Takaki, Manabu

Publication type:

Letter

Neonatal myoclonus in Bryant-Li-Bhoj syndrome associated with a novel H3F3A variant.

Published in:

Human Genome Variation, 2024, v. 11, n. 1, p. 1, doi. 10.1038/s41439-024-00303-x

By:

Hojo, Moemi;
Soma, Noriko;
Yamada, Kei;
Kobayashi, Yu;
Miura, Masaki;
Fujii, Hitomi;
Nyuzuki, Hiromi;
Nishio, Yosuke;
Oso, Taichi;
Ogi, Tomoo;
Ikeuchi, Takeshi;
Tohyama, Jun

Publication type:

Article

A severe case of cardiospondylocarpofacial syndrome with a novel MAP3K7 variant.

Published in:

Human Genome Variation, 2024, v. 11, n. 1, p. 1, doi. 10.1038/s41439-024-00265-0

By:

Nyuzuki, Hiromi;
Ozawa, Junichi;
Nagasaki, Keisuke;
Nishio, Yosuke;
Ogi, Tomoo;
Tohyama, Jun;
Ikeuchi, Takeshi

Publication type:

Article

Loss of kallikrein-related peptidase 7 exacerbates amyloid pathology in Alzheimer's disease model mice.

Published in:

EMBO Molecular Medicine, 2018, v. 10, n. 3, p. 1, doi. 10.15252/emmm.201708184

By:

Kidana, Kiwami;
Tatebe, Takuya;
Ito, Kaori;
Hara, Norikazu;
Kakita, Akiyoshi;
Saito, Takashi;
Takatori, Sho;
Ouchi, Yasuyoshi;
Ikeuchi, Takeshi;
Makino, Mitsuhiro;
Saido, Takaomi C;
Akishita, Masahiro;
Iwatsubo, Takeshi;
Hori, Yukiko;
Tomita, Taisuke

Publication type:

Article

Altered γ-secretase activity in mild cognitive impairment and Alzheimer's disease.

Published in:

EMBO Molecular Medicine, 2012, v. 4, n. 4, p. 344, doi. 10.1002/emmm.201200214

By:

Kakuda, Nobuto;
Shoji, Mikio;
Arai, Hiroyuki;
Furukawa, Katsutoshi;
Ikeuchi, Takeshi;
Akazawa, Kohei;
Takami, Mako;
Hatsuta, Hiroyuki;
Murayama, Shigeo;
Hashimoto, Yasuhiro;
Miyajima, Masakazu;
Arai, Hajime;
Nagashima, Yu;
Yamaguchi, Haruyasu;
Kuwano, Ryozo;
Nagaike, Kazuhiro;
Ihara, Yasuo

Publication type:

Article

The 28-amino acid form of an APLP1-derived Aβ-like peptide is a surrogate marker for Aβ42 production in the central nervous system.

Published in:

EMBO Molecular Medicine, 2009, v. 1, n. 4, p. 223, doi. 10.1002/emmm.200900026

By:

Yanagida, Kanta;
Okochi, Masayasu;
Tagami, Shinji;
Nakayama, Taisuke;
Kodama, Takashi S.;
Nishitomi, Kouhei;
Jiang, Jingwei;
Mori, Kohji;
Tatsumi, Shin-ichi;
Arai, Tetsuaki;
Ikeuchi, Takeshi;
Kasuga, Kensaku;
Tokuda, Takahiko;
Kondo, Masaki;
Ikeda, Masaki;
Deguchi, Kentaro;
Kazui, Hiroaki;
Tanaka, Toshihisa;
Morihara, Takashi;
Hashimoto, Ryota

Publication type:

Article

TDP- 43 mutation in familial amyotrophic lateral sclerosis.

Published in:

Annals of Neurology, 2008, v. 63, n. 4, p. 538, doi. 10.1002/ana.21392

By:

Yokoseki, Akio;
Shiga, Atsushi;
Tan, Chun-Feng;
Tagawa, Asako;
Kaneko, Hiroyuki;
Koyama, Akihide;
Eguchi, Hiroto;
Tsujino, Akira;
Ikeuchi, Takeshi;
Kakita, Akiyoshi;
Okamoto, Koichi;
Nishizawa, Masatoyo;
Takahashi, Hitoshi;
Onodera, Osamu

Publication type:

Article

A novel mutation in the GNE gene and a linkage disequilibrium in Japanese pedigrees.

Published in:

Annals of Neurology, 2002, v. 52, n. 4, p. 516, doi. 10.1002/ana.10341

By:

Arai, Aki;
Tanaka, Keiko;
Ikeuchi, Takeshi;
Igarashi, Shuichi;
Kobayashi, Hisashi;
Asaka, Tomoya;
Date, Hidetoshi;
Saito, Masaaki;
Tanaka, Hajime;
Kawasaki, Sari;
Uyama, Eiichiro;
Mizusawa, Hidehiro;
Fukuhara, Nobuyoshi;
Tsuji, Shoji

Publication type:

Article

Novel mutations, pseudo-dominant inheritance, and possible familial affects in patients with autosomal recessive juvenile parkinsonism.

Published in:

2000

By:

Maruyama, Mieko;
Ikeuchi, Takeshi;
Saito, Masaaki;
Ishikawa, Atsushi;
Yuasa, Tatsuhiko;
Tanaka, Hajime;
Hayashi, Shintaro;
Wakabayashi, Koichi;
Takahashi, Hitoshi;
Tsuji, Shoji;
Maruyama, M;
Ikeuchi, T;
Saito, M;
Ishikawa, A;
Yuasa, T;
Tanaka, H;
Hayashi, S;
Wakabayashi, K;
Takahashi, H;
Tsuji, S

Publication type:

journal article

Spinocerebellar ataxia type 6: CAG repeat expansion in α<sub>1a</sub> voltage-dependent calcium channel gene and clinical variations in japanese population.

Published in:

Annals of Neurology, 1997, v. 42, n. 6, p. 879, doi. 10.1002/ana.410420609

By:

Ikeuchi, Takeshi;
Takano, Hiroki;
Koide, Reiji;
Igarashi, Shuichi;
Tanaka, Hajime;
Tsuji, Shoji;
Takahashi, Hitoshi;
Horikawa, Yoh;
Honma, Yoshiaki;
Onishi, Yoji;
Nakao, Naoki;
Sahashi, Ko;
Tsukagoshi, Hiroshi;
Inoue, Kiyoharu

Publication type:

Article

Gene locus for autosomal recessive distal myopathy with rimmed vacuoles maps to chromosome 9.

Published in:

Annals of Neurology, 1997, v. 41, n. 4, p. 432, doi. 10.1002/ana.410410405

By:

Ikeuchi, Takeshi;
Asaka, Tomoya;
Saito, Masaaki;
Tanaka, Hajime;
Higuchi, Sari;
Tanaka, Keiko;
Saida, Kyoko;
Uyama, Eiichiro;
Mizusawa, Hidenobu;
Fukuhara, Nobuyoshi;
Nonaka, Ikuya;
Takamori, Masaharu;
Tsuji, Shoji

Publication type:

Article

Dentatorubral-pallidoluysian atrophy: Clinical features are closely related to unstable expansions of trinucleotide (CAG) repeat.

Published in:

Annals of Neurology, 1995, v. 37, n. 6, p. 769, doi. 10.1002/ana.410370610

By:

Ikeuchi, Takeshi;
Koide, Reiji;
Tanaka, Hajime;
Onodera, Osamu;
Igarashi, Shuichi;
Takahashi, Hitoshi;
Kondo, Rui;
Ishikawa, Atsushi;
Tomoda, Akemi;
Miike, Teruhisa;
Keiko Sato;
Ihara, Yuetsu;
Hayabara, Toshiyuki;
Isa, Fumiko;
Tanabe, Hitoshi;
Tokiguchi, Susumu;
Hayashi, Masataka;
Shimizu, Natsue;
Ikuta, Fusahiro;
Naito, Haruhiko

Publication type:

Article

A rare functional variant of SHARPIN attenuates the inflammatory response and associates with increased risk of late-onset Alzheimer's disease.

Published in:

Molecular Medicine, 2019, v. 25, n. 1, p. N.PAG, doi. 10.1186/s10020-019-0090-5

By:

Asanomi, Yuya;
Shigemizu, Daichi;
Miyashita, Akinori;
Mitsumori, Risa;
Mori, Taiki;
Hara, Norikazu;
Ito, Kaoru;
Niida, Shumpei;
Ikeuchi, Takeshi;
Ozaki, Kouichi

Publication type:

Article

Genetic Variations and Neuropathologic Features of Patients with PRKN Mutations.

Published in:

Movement Disorders, 2021, v. 36, n. 7, p. 1634, doi. 10.1002/mds.28521

By:

Seike, Naohiko;
Yokoseki, Akio;
Takeuchi, Ryoko;
Saito, Kento;
Miyahara, Hiroaki;
Miyashita, Akinori;
Ikeda, Tetsuhiko;
Aida, Izumi;
Nakajima, Takashi;
Kanazawa, Masato;
Wakabayashi, Masatoshi;
Toyoshima, Yasuko;
Takahashi, Hitoshi;
Matsumoto, Riki;
Toda, Tatsushi;
Onodera, Osamu;
Ishikawa, Atsushi;
Ikeuchi, Takeshi;
Kakita, Akiyoshi

Publication type:

Article

Structurally distinct α-synuclein fibrils induce robust parkinsonian pathology.

Published in:

2020

By:

Hayakawa, Hideki;
Nakatani, Rie;
Ikenaka, Kensuke;
Aguirre, Cesar;
Choong, Chi‐Jing;
Tsuda, Hiroshi;
Nagano, Seiichi;
Koike, Masato;
Ikeuchi, Takeshi;
Hasegawa, Masato;
Papa, Stella M.;
Nagai, Yoshitaka;
Mochizuki, Hideki;
Baba, Kousuke;
Choong, Chi-Jing

Publication type:

journal article

Possibility for Prevention of Type 2 Diabetes Mellitus and Dementia Using Three Kinds of Brown Rice Blends after High-Pressure Treatment.

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Foods, 2022, v. 11, n. 6, p. 818, doi. 10.3390/foods11060818

By:

Nakamura, Sumiko;
Ikeuchi, Takeshi;
Araki, Aki;
Kasuga, Kensaku;
Watanabe, Kenichi;
Hirayama, Masao;
Ito, Mitsutoshi;
Ohtsubo, Ken'ichi

Publication type:

Article

Sex difference in evolution of cognitive decline: studies on mouse model and the Dominantly Inherited Alzheimer Network cohort.

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Translational Psychiatry, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41398-023-02411-8

By:

Kommaddi, Reddy Peera;
Verma, Aditi;
Muniz-Terrera, Graciela;
Tiwari, Vivek;
Chithanathan, Keerthana;
Diwakar, Latha;
Gowaikar, Ruturaj;
Karunakaran, Smitha;
Malo, Palash Kumar;
Graff-Radford, Neill R.;
Day, Gregory S.;
Laske, Christoph;
Vöglein, Jonathan;
Nübling, Georg;
Ikeuchi, Takeshi;
Kasuga, Kensaku;
the Dominantly Inherited Alzheimer Network (DIAN);
Ravindranath, Vijayalakshmi

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Article

Novel Aspects of Hereditary Spastic Paraplegia: A Clinicopathologic and Biochemical Study of a Patient With a Heterozygous GCH1 Variant.

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Neuropathology & Applied Neurobiology, 2025, v. 51, n. 1, p. 1, doi. 10.1111/nan.70006

By:

Hongo, Shoko;
Ikeda, Tetsuhiko;
Tada, Mari;
Aida, Rina;
Ozawa, Tetsuo;
Hara, Norikazu;
Miyashita, Akinori;
Nakajima, Takashi;
Onodera, Osamu;
Ikeuchi, Takeshi;
Ichinose, Hiroshi;
Kakita, Akiyoshi

Publication type:

Article

Brain TDP‐43 pathology in corticobasal degeneration: Topographical correlation with neuronal loss.

Published in:

Neuropathology & Applied Neurobiology, 2022, v. 48, n. 3, p. 1, doi. 10.1111/nan.12786

By:

Sainouchi, Makoto;
Tada, Mari;
Fitrah, Yusran Ady;
Hara, Norikazu;
Tanaka, Kou;
Idezuka, Jiro;
Aida, Izumi;
Nakajima, Takashi;
Miyashita, Akinori;
Akazawa, Kohei;
Ikeuchi, Takeshi;
Onodera, Osamu;
Kakita, Akiyoshi

Publication type:

Article

Transcriptional downregulation of FAM3C/ILEI in the Alzheimer's brain.

Published in:

Human Molecular Genetics, 2022, v. 31, n. 1, p. 122, doi. 10.1093/hmg/ddab226

By:

Watanabe, Naoki;
Nakano, Masaki;
Mitsuishi, Yachiyo;
Hara, Norikazu;
Mano, Tatsuo;
Iwata, Atsushi;
Murayama, Shigeo;
Suzuki, Toshiharu;
Ikeuchi, Takeshi;
Nishimura, Masaki

Publication type:

Article

Disruption of a RAC1-centred network is associated with Alzheimer's disease pathology and causes age-dependent neurodegeneration.

Published in:

Human Molecular Genetics, 2020, v. 29, n. 5, p. 817, doi. 10.1093/hmg/ddz320

By:

Kikuchi, Masataka;
Sekiya, Michiko;
Hara, Norikazu;
Miyashita, Akinori;
Kuwano, Ryozo;
Ikeuchi, Takeshi;
Iijima, Koichi M;
Nakaya, Akihiro

Publication type:

Article

Alterations in Glycerolipid and Fatty Acid Metabolic Pathways in Alzheimer's Disease Identified by Urinary Metabolic Profiling: A Pilot Study.

Published in:

Frontiers in Neurology, 2021, v. 12, p. 1, doi. 10.3389/fneur.2021.719159

By:

Watanabe, Yumi;
Kasuga, Kensaku;
Tokutake, Takayoshi;
Kitamura, Kaori;
Ikeuchi, Takeshi;
Nakamura, Kazutoshi

Publication type:

Article

Serum BDNF as a Potential Biomarker of Alzheimer's Disease: Verification Through Assessment of Serum, Cerebrospinal Fluid, and Medial Temporal Lobe Atrophy.

Published in:

Frontiers in Neurology, 2021, v. 11, p. N.PAG, doi. 10.3389/fneur.2021.653267

By:

Mori, Yukiko;
Tsuji, Mayumi;
Oguchi, Tatsunori;
Kasuga, Kensaku;
Kimura, Atsushi;
Futamura, Akinori;
Sugimoto, Azusa;
Kasai, Hideyo;
Kuroda, Takeshi;
Yano, Satoshi;
Hieda, Sotaro;
Kiuchi, Yuji;
Ikeuchi, Takeshi;
Ono, Kenjiro

Publication type:

Article