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Phosphatase protector alpha4 (α4) is involved in adipocyte maintenance and mitochondrial homeostasis through regulation of insulin signaling.
Published in:
Nature Communications, 2022, v. 13, p. 1, doi. 10.1038/s41467-022-33842-4
By:
- Sakaguchi, Masaji;
- Okagawa, Shota;
- Okubo, Yuma;
- Otsuka, Yuri;
- Fukuda, Kazuki;
- Igata, Motoyuki;
- Kondo, Tatsuya;
- Sato, Yoshifumi;
- Yoshizawa, Tatsuya;
- Fukuda, Takaichi;
- Yamagata, Kazuya;
- Cai, Weikang;
- Tseng, Yu-Hua;
- Sakaguchi, Nobuo;
- Kahn, C. Ronald;
- Araki, Eiichi
Publication type:
Article
Ectopic ACTH-producing neuroendocrine tumor occurring with large recurrent metastatic pheochromocytoma: a case report.
Published in:
BMC Endocrine Disorders, 2022, v. 22, n. 1, p. 1, doi. 10.1186/s12902-022-01090-8
By:
- Saishouji, Fumi;
- Maeda, Sarie;
- Hamada, Hideaki;
- Kimura, Noriko;
- Tamanoi, Ai;
- Nishida, Saiko;
- Sakaguchi, Masaji;
- Igata, Motoyuki;
- Yokoo, Kiho;
- Kawakami, Fumi;
- Araki, Eiichi;
- Kondo, Tatsuya
Publication type:
Article
Mineralocorticoid Receptor May Regulate Glucose Homeostasis through the Induction of Interleukin-6 and Glucagon-Like peptide-1 in Pancreatic Islets.
Published in:
Journal of Clinical Medicine, 2019, v. 8, n. 5, p. 674, doi. 10.3390/jcm8050674
By:
- Goto, Rieko;
- Kondo, Tatsuya;
- Ono, Kaoru;
- Kitano, Sayaka;
- Miyakawa, Nobukazu;
- Watanabe, Takuro;
- Sakaguchi, Masaji;
- Sato, Miki;
- Igata, Motoyuki;
- Kawashima, Junji;
- Motoshima, Hiroyuki;
- Matsumura, Takeshi;
- Shimoda, Seiya;
- Araki, Eiichi
Publication type:
Article
AMPK and cell proliferation – AMPK as a therapeutic target for atherosclerosis and cancer.
Published in:
Journal of Physiology, 2006, v. 574, n. 1, p. 63, doi. 10.1113/jphysiol.2006.108324
By:
- Motoshima, Hiroyuki;
- Goldstein, Barry J.;
- Igata, Motoyuki;
- Araki, Eiichi
Publication type:
Article
Autoimmune Polyglandular Syndrome Type 3 Complicated with IgG4-related Disease.
Published in:
Internal Medicine, 2024, v. 63, n. 3, p. 425, doi. 10.2169/internalmedicine.1270-22
By:
- Yusuke Murata;
- Masaki Haneda;
- Nobukazu Miyakawa;
- Saiko Nishida;
- Nobuhiro Kajihara;
- Sarie Maeda;
- Kaoru Ono;
- Satoko Hanatani;
- Motoyuki Igata;
- Yuki Takaki;
- Hiroyuki Motoshima;
- Hideki Kishikawa;
- Eiichi Araki
Publication type:
Article
Activation of heat shock response to treat obese subjects with type 2 diabetes: a prospective, frequency-escalating, randomized, open-label, triple-arm trial.
Published in:
Scientific Reports, 2016, p. 35690, doi. 10.1038/srep35690
By:
- Kondo, Tatsuya;
- Goto, Rieko;
- Ono, Kaoru;
- Kitano, Sayaka;
- Suico, Mary Ann;
- Sato, Miki;
- Igata, Motoyuki;
- Kawashima, Junji;
- Motoshima, Hiroyuki;
- Matsumura, Takeshi;
- Kai, Hirofumi;
- Araki, Eiichi
Publication type:
Article
The Role of Heat Shock Response in Insulin Resistance and Diabetes.
Published in:
Diabetes & Metabolism Journal, 2014, v. 38, n. 2, p. 100, doi. 10.4093/dmj.2014.38.2.100
By:
- Kondo, Tatsuya;
- Motoshima, Hiroyuki;
- Igata, Motoyuki;
- Kawashima, Junji;
- Matsumura, Takeshi;
- Kai, Hirofumi;
- Araki, Eiichi
Publication type:
Article
Rapid and dramatic glucose‐lowering effect of bromocriptine in an inadequately controlled type 2 diabetes patient with prolactinoma.
Published in:
Journal of Diabetes Investigation, 2021, v. 12, n. 4, p. 668, doi. 10.1111/jdi.13369
By:
- Igata, Motoyuki;
- Yagi, Yoshitaka;
- Hanatani, Satoko;
- Sakaguchi, Masaji;
- Ishii, Norio;
- Yoshinaga, Kayo;
- Kawashima, Junji;
- Motoshima, Hiroyuki;
- Araki, Eiichi
Publication type:
Article
Impacts of the 2016 Kumamoto Earthquake on glycemic control in patients with diabetes.
Published in:
Journal of Diabetes Investigation, 2019, v. 10, n. 2, p. 521, doi. 10.1111/jdi.12891
By:
- Kondo, Tatsuya;
- Miyakawa, Nobukazu;
- Motoshima, Hiroyuki;
- Hanatani, Satoko;
- Ishii, Norio;
- Igata, Motoyuki;
- Yoshinaga, Kayo;
- Kukidome, Daisuke;
- Senokuchi, Takafumi;
- Kawashima, Junji;
- Furukawa, Noboru;
- Matsumura, Takeshi;
- Araki, Eiichi
Publication type:
Article
A 1-year, prospective, observational study of Japanese outpatients with type 1 and type 2 diabetes switching from insulin glargine or detemir to insulin degludec in basal-bolus insulin therapy (Kumamoto Insulin Degludec Observational study).
Published in:
Journal of Diabetes Investigation, 2016, v. 7, n. 5, p. 703, doi. 10.1111/jdi.12496
By:
- Shimoda, Seiya;
- Sato, Miki;
- Sekigami, Taiji;
- Motoshima, Hiroyuki;
- Yoshimura, Ryohei;
- Fukuda, Kazuki;
- Matsuo, Yasuto;
- Noda, Hideyuki;
- Okubo, Mina;
- Ichimori, Shinji;
- Fujisawa, Kazuo;
- Fukunaga, Makiko;
- Araki, Eiichi;
- Nishikawa, Takeshi;
- Furukawa, Noboru;
- Matsumura, Takeshi;
- Kondo, Tatsuya;
- Kawashima, Junji;
- Senokuchi, Takafumi;
- Igata, Motoyuki
Publication type:
Article
Effects of combination therapy with vildagliptin and valsartan in a mouse model of type 2 diabetes.
Published in:
Cardiovascular Diabetology, 2013, v. 12, n. 1, p. 1, doi. 10.1186/1475-2840-12-160
By:
- Miyagawa, Katsutosh;
- Kondo, Tatsuya;
- Goto, Rieko;
- Matsuyama, Rina;
- Ono, Kaoru;
- Kitano, Sayaka;
- Kawasaki, Shuji;
- Igata, Motoyuki;
- Kawashima, Junji;
- Matsumura, Takeshi;
- Motoshima, Hiroyuki;
- Araki, Eiichi
Publication type:
Article
CRTC3 links catecholamine signalling to energy balance.
Published in:
Nature, 2010, v. 468, n. 7326, p. 933, doi. 10.1038/nature09564
By:
- Youngsup Song;
- Altarejos, Judith;
- Goodarzi, Mark O.;
- Inoue, Hiroshi;
- Guo, Xiuqing;
- Berdeaux, Rebecca;
- Kim, Jeong-Ho;
- Goode, Jason;
- Igata, Motoyuki;
- Paz, Jose C.;
- Hogan, Meghan F.;
- Singh, Pankaj K.;
- Goebel, Naomi;
- Vera, Lili;
- Miller, Nina;
- Cui, Jinrui;
- Jones, Michelle R.;
- Chen, Yii-Der I.;
- Taylor, Kent D.;
- Hsueh, Willa A.
Publication type:
Article
Rottlerin, a PKC-delta Inhibitor, Strongly Suppresses Cell Cycle Progression in Vascular Smooth Muscle Cell Through AMPK Activation.
Published in:
Diabetes, 2007, v. 56, p. A599
By:
- Motoshima, Hiroyuki;
- Kojima, Kanou;
- Igata, Motoyuki;
- Tsutsumi, Atsuyuki;
- Kondo, Tatsuya;
- Matsumura, Takeshi;
- Furukawa, Noboru;
- Tsuruzoe, Kaku;
- Nishikawa, Takeshi;
- Araki, Eiichi
Publication type:
Article
Irs-1 Transgenic Mice Showed Increased Epididymal Fat Mass and Displayed Insulin Resistance In Vivo.
Published in:
Diabetes, 2007, v. 56, p. A346
By:
- Murata, Yusuke;
- Tsuruzoe, Kaku;
- Toyonaga, Tetushi;
- Furukawa, Noboru;
- Kondo, Tatsuya;
- Motoshima, Hiroyuki;
- Igata, Motoyuki;
- Taketa, Kayo;
- Sasaki, Kazunari;
- Araki, Eiichi
Publication type:
Article
Insulin requirement profiles in Japanese hospitalized subjects with type 2 diabetes treated with basal-bolus insulin therapy.
Published in:
Endocrine Journal, 2015, v. 62, n. 2, p. 209, doi. 10.1507/endocrj.ej14-0487
By:
- Seiya Shimoda;
- Mina Okubo;
- Kotaro Koga;
- Taiji Sekigami;
- Junji Kawashima;
- Daisuke Kukidome;
- Motoyuki Igata;
- Norio Ishii;
- Akiko Shimakawa;
- Takeshi Matsumura;
- Hiroyuki Motoshima;
- Noboru Furukawa;
- Kenro Nishida;
- Eiichi Araki
Publication type:
Article
Identification of microRNA that represses IRS-1 expression in liver.
Published in:
PLoS ONE, 2018, v. 13, n. 1, p. 1, doi. 10.1371/journal.pone.0191553
By:
- Ono, Kaoru;
- Igata, Motoyuki;
- Kondo, Tatsuya;
- Kitano, Sayaka;
- Takaki, Yuki;
- Hanatani, Satoko;
- Sakaguchi, Masaji;
- Goto, Rieko;
- Senokuchi, Takafumi;
- Kawashima, Junji;
- Furukawa, Noboru;
- Motoshima, Hiroyuki;
- Araki, Eiichi
Publication type:
Article
29-OR: Regulatory Loop of IR Signaling for Adipocyte Mitochondrial Homeostasis.
Published in:
Diabetes, 2021, v. 70, p. N.PAG, doi. 10.2337/db21-29-OR
By:
- SAKAGUCHI, MASAJI;
- OKAGAWA, SHOTA;
- OKUBO, YUMA;
- FUKUDA, KAZUKI;
- IGATA, MOTOYUKI;
- KAWASHIMA, JUNJI;
- KONDO, TATSUYA;
- ARAKI, EIICHI
Publication type:
Article
1714-P: Regulation of Phosphorylation Status in Insulin Signaling via a4 Is Necessary for Adipocyte Maintenance and Lipid Dynamics.
Published in:
Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-1714-P
By:
- SAKAGUCHI, MASAJI;
- OKAGAWA, SHOTA;
- OKUBO, YUMA;
- KITANO, SAYAKA;
- IGATA, MOTOYUKI;
- KONDO, TATSUYA;
- ARAKI, EIICHI
Publication type:
Article
1072-P: Activation of Heat Shock Response Ameliorates Nonalcoholic Fatty Liver Disease Biomarkers.
Published in:
Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-1072-P
By:
- KONDO, TATSUYA;
- KITANO, SAYAKA;
- MIYAKAWA, NOBUKAZU;
- WATANABE, TAKURO;
- GOTO, RIEKO;
- SAKAGUCHI, MASAJI;
- IGATA, MOTOYUKI;
- KAWASHIMA, JUNJI;
- MOTOSHIMA, HIROYUKI;
- MATSUMURA, TAKESHI;
- ARAKI, EIICHI
Publication type:
Article
1863-P: The Hepatic Role of Heat Shock Protein 72 in the Pathogenesis of Type 2 Diabetes.
Published in:
Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-1863-P
By:
- KONDO, TATSUYA;
- KITANO, SAYAKA;
- MIYAKAWA, NOBUKAZU;
- WATANABE, TAKURO;
- GOTO, RIEKO;
- ONO, KAORU;
- IGATA, MOTOYUKI;
- KAWASHIMA, JUNJI;
- MOTOSHIMA, HIROYUKI;
- MATSUMURA, TAKESHI;
- ARAKI, EIICHI
Publication type:
Article

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