Works by Huyghe, Jeroen R.

Results: 29

Identifying metabolic features of colorectal cancer liability using Mendelian randomization.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.87894

By:

Bull, Caroline;
Hazelwood, Emma;
Bell, Joshua A.;
Tan, Vanessa;
Constantinescu, Andrei-Emil;
Borges, Carolina;
Legge, Danny;
Burrows, Kimberley;
Huyghe, Jeroen R.;
Brenner, Hermann;
Castellvi-Bel, Sergi;
Chan, Andrew T.;
Sun-Seog Kweon;
Le Marchand, Loic;
Li Li;
Cheng, Iona;
Pai, Rish K.;
Figueiredo, Jane C.;
Murphy, Neil;
Gunter, Marc J.

Publication type:

Article

A genome-wide analysis of population structure in the Finnish Saami with implications for genetic association studies.

Published in:

European Journal of Human Genetics, 2011, v. 19, n. 3, p. 347, doi. 10.1038/ejhg.2010.179

By:

Huyghe, Jeroen R.;
Fransen, Erik;
Hannula, Samuli;
Van Laer, Lut;
Van Eyken, Els;
Mäki-Torkko, Elina;
Aikio, Pekka;
Sorri, Martti;
Huentelman, Matthew J.;
Camp, Guy Van

Publication type:

Article

A genome-wide association study for age-related hearing impairment in the Saami.

Published in:

European Journal of Human Genetics, 2010, v. 18, n. 6, p. 685, doi. 10.1038/ejhg.2009.234

By:

Van Laer, Lut;
Huyghe, Jeroen R.;
Hannula, Samuli;
Van Eyken, Els;
Stephan, Dietrich A.;
Mäki-Torkko, Elina;
Aikio, Pekka;
Fransen, Erik;
Lysholm-Bernacchi, Alana;
Sorri, Martti;
Huentelman, Matthew J.;
Van Camp, Guy

Publication type:

Article

Genome-wide SNP analysis reveals no gain in power for association studies of common variants in the Finnish Saami.

Published in:

European Journal of Human Genetics, 2010, v. 18, n. 5, p. 569, doi. 10.1038/ejhg.2009.210

By:

Huyghe, Jeroen R.;
Fransen, Erik;
Hannula, Samuli;
Van Laer, Lut;
Van Eyken, Els;
Mäki-Torkko, Elina;
Lysholm-Bernacchi, Alana;
Aikio, Pekka;
Stephan, Dietrich A.;
Sorri, Martti;
Huentelman, Matthew J.;
Van Camp, Guy

Publication type:

Article

Assessment of a Polygenic Risk Score for Colorectal Cancer to Predict Risk of Lynch Syndrome Colorectal Cancer.

Published in:

JNCI Cancer Spectrum, 2021, v. 5, n. 2, p. 1, doi. 10.1093/jncics/pkab022

By:

Jenkins, Mark A;
Buchanan, Daniel D;
Lai, John;
Makalic, Enes;
Dite, Gillian S;
Win, Aung K;
Clendenning, Mark;
Winship, Ingrid M;
Hayes, Richard B;
Huyghe, Jeroen R;
Peters, Ulrike;
Gallinger, Steven;
Marchand, Loïc Le;
Figueiredo, Jane C;
Pai, Rish K;
Newcomb, Polly A;
Church, James M;
Casey, Graham;
Hopper, John L

Publication type:

Article

Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion.

Published in:

Nature Genetics, 2013, v. 45, n. 2, p. 197, doi. 10.1038/ng.2507

By:

Huyghe, Jeroen R;
Jackson, Anne U;
Fogarty, Marie P;
Buchkovich, Martin L;
Stan?áková, Alena;
Stringham, Heather M;
Sim, Xueling;
Yang, Lingyao;
Fuchsberger, Christian;
Cederberg, Henna;
Chines, Peter S;
Teslovich, Tanya M;
Romm, Jane M;
Ling, Hua;
McMullen, Ivy;
Ingersoll, Roxann;
Pugh, Elizabeth W;
Doheny, Kimberly F;
Neale, Benjamin M;
Daly, Mark J

Publication type:

Article

Evaluation of host genetic and viral factors as surrogate markers for HTLV-1-associated myelopathy/tropical spastic paraparesis in Peruvian HTLV-1-infected patients.

Published in:

Journal of Medical Virology, 2010, v. 82, n. 3, p. 460, doi. 10.1002/jmv.21675

By:

Talledo, Michael;
López, Giovanni;
Huyghe, Jeroen R.;
Verdonck, Kristien;
Adaui, Vanessa;
González, Elsa;
Best, Iván;
Clark, Daniel;
Vanham, Guido;
Gotuzzo, Eduardo;
Van Camp, Guy;
Van Laer, Lut

Publication type:

Article

Novel insights into genetic susceptibility for colorectal cancer from transcriptome-wide association and functional investigation.

Published in:

JNCI: Journal of the National Cancer Institute, 2024, v. 116, n. 1, p. 127, doi. 10.1093/jnci/djad178

By:

Chen, Zhishan;
Song, Wenqiang;
Shu, Xiao-Ou;
Wen, Wanqing;
Devall, Matthew;
Dampier, Christopher;
Moratalla-Navarro, Ferran;
Cai, Qiuyin;
Long, Jirong;
Kaer, Luc Van;
Wu, Lan;
Huyghe, Jeroen R;
Thomas, Minta;
Hsu, Li;
Woods, Michael O;
Albanes, Demetrius;
Buchanan, Daniel D;
Gsur, Andrea;
Hoffmeister, Michael;
Vodicka, Pavel

Publication type:

Article

Genome-Wide Interaction Analysis of Genetic Variants With Menopausal Hormone Therapy for Colorectal Cancer Risk.

Published in:

2022

By:

Tian, Yu;
Kim, Andre E;
Bien, Stephanie A;
Lin, Yi;
Qu, Conghui;
Harrison, Tabitha A;
Carreras-Torres, Robert;
Díez-Obrero, Virginia;
Dimou, Niki;
Drew, David A;
Hidaka, Akihisa;
Huyghe, Jeroen R;
Jordahl, Kristina M;
Morrison, John;
Murphy, Neil;
Obón-Santacana, Mireia;
Ulrich, Cornelia M;
Ose, Jennifer;
Peoples, Anita R;
Ruiz-Narvaez, Edward A

Publication type:

journal article

The grainyhead like 2 gene (GRHL2), alias TFCP2L3, is associated with age-related hearing impairment.

Published in:

Human Molecular Genetics, 2008, v. 17, n. 2, p. 159, doi. 10.1093/hmg/ddm292

By:

Van Laer, Lut;
Van Eyken, Els;
Fransen, Erik;
Huyghe, Jeroen R.;
Topsakal, Vedat;
Hendrickx, Jan-Jaap;
Hannula, Samuli;
Mäki-Torkko, Elina;
Jensen, Mona;
Demeester, Kelly;
Baur, Manuela;
Bonaconsa, Amanda;
Mazzoli, Manuela;
Espeso, Angeles;
Verbruggen, Katia;
Huyghe, Joke;
Huygen, Patrick;
Kunst, Sylvia;
Manninen, Minna;
Konings, Annelies

Publication type:

Article

One-carbon metabolism biomarkers and genetic variants in relation to colorectal cancer risk by KRAS and BRAF mutation status.

Published in:

PLoS ONE, 2018, v. 13, n. 4, p. 1, doi. 10.1371/journal.pone.0196233

By:

Myte, Robin;
Gylling, Björn;
Häggström, Jenny;
Schneede, Jörn;
Löfgren-Burström, Anna;
Huyghe, Jeroen R.;
Hallmans, Göran;
Meyer, Klaus;
Johansson, Ingegerd;
Ueland, Per Magne;
Palmqvist, Richard;
Van Guelpen, Bethany

Publication type:

Article

Association of Bone Morphogenetic Proteins With Otosclerosis.

Published in:

Journal of Bone & Mineral Research, 2008, v. 23, n. 4, p. 507, doi. 10.1359/JBMR.071112

By:

Schrauwen, Isabelle;
Thys, Melissa;
Vanderstraeten, Kathleen;
Fransen, Erik;
Dieltjens, Nele;
Huyghe, Jeroen R.;
Ealy, Megan;
Claustres, Mireille;
Cremers, Cor R. W. J.;
Dhooge, Ingeborg;
Declau, Frank;
Van De Heyning, Paul;
Vincent, Robert;
Somers, Thomas;
Offeciers, Erwin;
Smith, Richard J. H.;
Van Camp, Guy

Publication type:

Article

T cell‐inflamed gene expression profile is associated with favorable disease‐specific survival in non‐hypermutated microsatellite‐stable colorectal cancer patients.

Published in:

Cancer Medicine, 2023, v. 12, n. 6, p. 6583, doi. 10.1002/cam4.5429

By:

Yin, Hang;
Harrison, Tabitha A.;
Thomas, Sushma S.;
Sather, Cassie L.;
Koehne, Amanda L.;
Malen, Rachel C.;
Reedy, Adriana M.;
Wurscher, Michelle A.;
Hsu, Li;
Phipps, Amanda I.;
Zaidi, Syed H. E.;
Newcomb, Polly A.;
Peters, Ulrike;
Huyghe, Jeroen R.

Publication type:

Article

Association between somatic microsatellite instability, hypermutation status, and specific T cell subsets in colorectal cancer tumors.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2024.1505896

By:

Thomas, Claire E.;
Takashima, Yasutoshi;
Wesselink, Evertine;
Ugai, Tomotaka;
Steinfelder, Robert S.;
Buchanan, Daniel D.;
Qu, Conghui;
Hsu, Li;
Dias Costa, Andressa;
Gallinger, Steven;
Grant, Robert C.;
Huyghe, Jeroen R.;
Thomas, Sushma S.;
Ogino, Shuji;
Phipps, Amanda I.;
Nowak, Jonathan A.;
Peters, Ulrike

Publication type:

Article

The genetic regulatory signature of type 2 diabetes in human skeletal muscle.

Published in:

Nature Communications, 2016, v. 7, n. 6, p. 11764, doi. 10.1038/ncomms11764

By:

Scott, Laura J.;
Erdos, Michael R.;
Huyghe, Jeroen R.;
Welch, Ryan P.;
Beck, Andrew T.;
Wolford, Brooke N.;
Chines, Peter S.;
Didion, John P.;
Narisu, Narisu;
Stringham, Heather M.;
Taylor, D. Leland;
Jackson, Anne U.;
Vadlamudi, Swarooparani;
Bonnycastle, Lori L.;
Kinnunen, Leena;
Saramies, Jouko;
Sundvall, Jouko;
Albanus, Ricardo D'Oliveira;
Kiseleva, Anna;
Hensley, John

Publication type:

Article

Possible implication of NFKB1A and NKG2D genes in susceptibility to HTLV-1-associated myelopathy/tropical spastic paraparesis in Peruvian patients infected with HTLV-1.

Published in:

Journal of Medical Virology, 2012, v. 84, n. 2, p. 319, doi. 10.1002/jmv.22255

By:

Talledo, Michael;
López, Giovanni;
Huyghe, Jeroen R.;
Verdonck, Kristien;
González, Elsa;
Clark, Daniel;
Vanham, Guido;
Gotuzzo, Eduardo;
Van Camp, Guy;
Van Laer, Lut

Publication type:

Article

Genetic signature of population fragmentation varies with mobility in seven bird species of a fragmented Kenyan cloud forest.

Published in:

Molecular Ecology, 2011, v. 20, n. 9, p. 1829, doi. 10.1111/j.1365-294X.2011.05028.x

By:

CALLENS, TOM;
GALBUSERA, PETER;
MATTHYSEN, ERIK;
DURAND, ERIC Y.;
GITHIRU, MWANGI;
HUYGHE, JEROEN R.;
LENS, LUC

Publication type:

Article

Autosomal Dominant Diabetes Arising From a Wolfram Syndrome 1 Mutation.

Published in:

Diabetes, 2013, v. 62, n. 11, p. 3943, doi. 10.2337/db13-0571

By:

Bonnycastle, Lori L.;
Chines, Peter S.;
Takashi Hara;
Huyghe, Jeroen R.;
Swift, Amy J.;
Heikinheimo, Pirkko;
Mahadevan, Jana;
Peltonen, Sirkku;
Huopio, Hanna;
Nuutila, Pirjo;
Narisu, Narisu;
Goldfeder, Rachel L.;
Stitzel, Michael L.;
Simin Lu;
Boehnke, Michael;
Urano, Fumihiko;
Collins, Francis S.;
Laakso, Markku

Publication type:

Article

A general framework for functionally informed set-based analysis: Application to a large-scale colorectal cancer study.

Published in:

PLoS Genetics, 2020, v. 16, n. 8, p. 1, doi. 10.1371/journal.pgen.1008947

By:

Dong, Xinyuan;
Su, Yu-Ru;
Barfield, Richard;
Bien, Stephanie A.;
He, Qianchuan;
Harrison, Tabitha A.;
Huyghe, Jeroen R.;
Keku, Temitope O.;
Lindor, Noralane M.;
Schafmayer, Clemens;
Chan, Andrew T.;
Gruber, Stephen B.;
Jenkins, Mark A.;
Kooperberg, Charles;
Peters, Ulrike;
Hsu, Li

Publication type:

Article

Ethanol exposure drives colon location specific cell composition changes in a normal colon crypt 3D organoid model.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-020-80240-1

By:

Devall, Matthew;
Plummer, Sarah J.;
Bryant, Jennifer;
Jennelle, Lucas T.;
Eaton, Stephen;
Dampier, Christopher H.;
Huyghe, Jeroen R.;
Peters, Ulrike;
Powell, Steven M.;
Casey, Graham

Publication type:

Article

Circulating white blood cell traits and colorectal cancer risk: A Mendelian randomisation study.

Published in:

International Journal of Cancer, 2024, v. 154, n. 1, p. 94, doi. 10.1002/ijc.34691

By:

Constantinescu, Andrei‐Emil;
Bull, Caroline J.;
Jones, Nicholas;
Mitchell, Ruth;
Burrows, Kimberley;
Dimou, Niki;
Bézieau, Stéphane;
Brenner, Hermann;
Buchanan, Daniel D.;
D'Amato, Mauro;
Jenkins, Mark A.;
Moreno, Victor;
Pai, Rish K.;
Um, Caroline Y.;
White, Emily;
Murphy, Neil;
Gunter, Marc;
Timpson, Nicholas J.;
Huyghe, Jeroen R.;
Vincent, Emma E.

Publication type:

Article

Host genetic factors associated to proviral load in Peruvian HTLV-1 infected.

Published in:

2011

By:

Talledo, Michael;
López, Giovanni;
Huyghe, Jeroen R.;
Verdonck, Kristien;
González, Elsa;
Tipismana, Martin;
Clark, Daniel;
Vanham, Guido;
Gotuzzo, Eduardo;
Van Camp, Guy;
Van Laer, Lut

Publication type:

Abstract

Novel Common Genetic Susceptibility Loci for Colorectal Cancer.

Published in:

2019

By:

Schmit, Stephanie L;
Edlund, Christopher K;
Schumacher, Fredrick R;
Gong, Jian;
Harrison, Tabitha A;
Huyghe, Jeroen R;
Qu, Chenxu;
Melas, Marilena;
Berg, David J Van Den;
Wang, Hansong;
Tring, Stephanie;
Plummer, Sarah J;
Albanes, Demetrius;
Alonso, M Henar;
Amos, Christopher I;
Anton, Kristen;
Aragaki, Aaron K;
Arndt, Volker;
Barry, Elizabeth L;
Berndt, Sonja I

Publication type:

journal article

Association between germline variants and somatic mutations in colorectal cancer.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-14408-2

By:

Barfield, Richard;
Qu, Conghui;
Steinfelder, Robert S.;
Zeng, Chenjie;
Harrison, Tabitha A.;
Brezina, Stefanie;
Buchanan, Daniel D.;
Campbell, Peter T.;
Casey, Graham;
Gallinger, Steven;
Giannakis, Marios;
Gruber, Stephen B.;
Gsur, Andrea;
Hsu, Li;
Huyghe, Jeroen R.;
Moreno, Victor;
Newcomb, Polly A.;
Ogino, Shuji;
Phipps, Amanda I.;
Slattery, Martha L.

Publication type:

Article

Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study.

Published in:

PLoS Genetics, 2017, v. 13, n. 10, p. 1, doi. 10.1371/journal.pgen.1007079

By:

Davis, James P.;
Huyghe, Jeroen R.;
Locke, Adam E.;
Jackson, Anne U.;
Sim, Xueling;
Stringham, Heather M.;
Teslovich, Tanya M.;
Welch, Ryan P.;
Fuchsberger, Christian;
Narisu, Narisu;
Chines, Peter S.;
Kangas, Antti J.;
Soininen, Pasi;
Ala-Korpela, Mika;
Kuusisto, Johanna;
Collins, Francis S.;
Laakso, Markku;
Boehnke, Michael;
Mohlke, Karen L.

Publication type:

Article

Identification of seven novel loci associated with amino acid levels using single-variant and gene-based tests in 8545 Finnish men from the METSIM study.

Published in:

Human Molecular Genetics, 2018, v. 27, n. 9, p. 1664, doi. 10.1093/hmg/ddy067

By:

Teslovich, Tanya M.;
Kim, Daniel Seung;
Xianyong Yin;
Stančcáková, Alena;
Jackson, Anne U.;
Wielscher, Matthias;
Naj, Adam;
Perry, John R. B.;
Huyghe, Jeroen R.;
Stringham, Heather M.;
Davis, James P.;
Raulerson, Chelsea K.;
Welch, Ryan P.;
Fuchsberger, Christian;
Locke, Adam E.;
Xueling Sim;
Chines, Peter S.;
Narisu, Narisu;
Kangas, Antti J.;
Soininen, Pasi

Publication type:

Article

Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms.

Published in:

Human Molecular Genetics, 2016, v. 25, n. 10, p. 2070, doi. 10.1093/hmg/ddw048

By:

Horikoshi, Momoko;
Pasquali, Lorenzo;
Wiltshire, Steven;
Huyghe, Jeroen R.;
Mahajan, Anubha;
Asimit, Jennifer L.;
Ferreira, Teresa;
Locke, Adam E.;
Robertson, Neil R.;
Xu Wang;
Xueling Sim;
Hayato Fujita;
Kazuo Hara;
Young, Robin;
Weihua Zhang;
Sungkyoung Choi;
Han Chen;
Kaur, Ismeet;
Fumihiko Takeuchi;
Fontanillas, Pierre

Publication type:

Article

Publisher Correction: Shared heritability and functional enrichment across six solid cancers.

Published in:

2019

By:

Jiang, Xia;
Finucane, Hilary K.;
Schumacher, Fredrick R.;
Schmit, Stephanie L.;
Tyrer, Jonathan P.;
Han, Younghun;
Michailidou, Kyriaki;
Lesseur, Corina;
Kuchenbaecker, Karoline B.;
Dennis, Joe;
Conti, David V.;
Casey, Graham;
Gaudet, Mia M.;
Huyghe, Jeroen R.;
Albanes, Demetrius;
Aldrich, Melinda C.;
Andrew, Angeline S.;
Andrulis, Irene L.;
Anton-Culver, Hoda;
Antoniou, Antonis C.

Publication type:

Correction Notice

Shared heritability and functional enrichment across six solid cancers.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-018-08054-4

By:

Jiang, Xia;
Finucane, Hilary K.;
Schumacher, Fredrick R.;
Schmit, Stephanie L.;
Tyrer, Jonathan P.;
Han, Younghun;
Michailidou, Kyriaki;
Lesseur, Corina;
Kuchenbaecker, Karoline B.;
Dennis, Joe;
Conti, David V.;
Casey, Graham;
Gaudet, Mia M.;
Huyghe, Jeroen R.;
Albanes, Demetrius;
Aldrich, Melinda C.;
Andrew, Angeline S.;
Andrulis, Irene L.;
Anton-Culver, Hoda;
Antoniou, Antonis C.

Publication type:

Article