Works matching AU Hutter, Barbara

Results: 30
    1

    NCT/DKFZ MASTER handbook of interpreting whole-genome, transcriptome, and methylome data for precision oncology.

    Published in:
    NPJ Precision Oncology, 2023, v. 7, n. 1, p. 1, doi. 10.1038/s41698-023-00458-w
    By:
    • Mock, Andreas;
    • Teleanu, Maria-Veronica;
    • Kreutzfeldt, Simon;
    • Heilig, Christoph E.;
    • Hüllein, Jennifer;
    • Möhrmann, Lino;
    • Jahn, Arne;
    • Hanf, Dorothea;
    • Kerle, Irina A.;
    • Singh, Hans Martin;
    • Hutter, Barbara;
    • Uhrig, Sebastian;
    • Fröhlich, Martina;
    • Neumann, Olaf;
    • Hartig, Andreas;
    • Brückmann, Sascha;
    • Hirsch, Steffen;
    • Grund, Kerstin;
    • Dikow, Nicola;
    • Lipka, Daniel B.
    Publication type:
    Article
    2

    Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma.

    Published in:
    Nature Genetics, 2013, v. 45, n. 8, p. 927, doi. 10.1038/ng.2682
    By:
    • Jones, David T W;
    • Hutter, Barbara;
    • Jäger, Natalie;
    • Korshunov, Andrey;
    • Kool, Marcel;
    • Warnatz, Hans-Jörg;
    • Zichner, Thomas;
    • Lambert, Sally R;
    • Ryzhova, Marina;
    • Quang, Dong Anh Khuong;
    • Fontebasso, Adam M;
    • Stütz, Adrian M;
    • Hutter, Sonja;
    • Zuckermann, Marc;
    • Sturm, Dominik;
    • Gronych, Jan;
    • Lasitschka, Bärbel;
    • Schmidt, Sabine;
    • Şeker-Cin, Huriye;
    • Witt, Hendrik
    Publication type:
    Article
    3
    4
    5

    Comprehensive genomic and epigenomic analysis in cancer of unknown primary guides molecularly-informed therapies despite heterogeneity.

    Published in:
    Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-31866-4
    By:
    • Möhrmann, Lino;
    • Werner, Maximilian;
    • Oleś, Małgorzata;
    • Mock, Andreas;
    • Uhrig, Sebastian;
    • Jahn, Arne;
    • Kreutzfeldt, Simon;
    • Fröhlich, Martina;
    • Hutter, Barbara;
    • Paramasivam, Nagarajan;
    • Richter, Daniela;
    • Beck, Katja;
    • Winter, Ulrike;
    • Pfütze, Katrin;
    • Heilig, Christoph E.;
    • Teleanu, Veronica;
    • Lipka, Daniel B.;
    • Zapatka, Marc;
    • Hanf, Dorothea;
    • List, Catrin
    Publication type:
    Article
    6
    7

    Ruxolitinib is effective in the treatment of a patient with refractory T‐ALL.

    Published in:
    EJHaem, 2021, v. 2, n. 1, p. 139, doi. 10.1002/jha2.143
    By:
    • Jaramillo, Sonia;
    • Hennemann, Hannah;
    • Horak, Peter;
    • Teleanu, Veronica;
    • Heilig, Christoph E.;
    • Hutter, Barbara;
    • Stenzinger, Albrecht;
    • Glimm, Hanno;
    • Goeppert, Benjamin;
    • Müller‐Tidow, Carsten;
    • Fröhling, Stefan;
    • Schönland, Stefan;
    • Schlenk, Richard F.
    Publication type:
    Article
    8

    Integrative analysis of single-cell expression data reveals distinct regulatory states in bidirectional promoters.

    Published in:
    Epigenetics & Chromatin, 2018, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13072-018-0236-7
    By:
    • Behjati Ardakani, Fatemeh;
    • Kattler, Kathrin;
    • Nordström, Karl;
    • Gasparoni, Nina;
    • Gasparoni, Gilles;
    • Fuchs, Sarah;
    • Sinha, Anupam;
    • Barann, Matthias;
    • Ebert, Peter;
    • Fischer, Jonas;
    • Hutter, Barbara;
    • Zipprich, Gideon;
    • Imbusch, Charles D.;
    • Felder, Bärbel;
    • Eils, Jürgen;
    • Brors, Benedikt;
    • Lengauer, Thomas;
    • Manke, Thomas;
    • Rosenstiel, Philip;
    • Walter, Jörn
    Publication type:
    Article
    9

    Precision oncology based on omics data: The NCT Heidelberg experience.

    Published in:
    International Journal of Cancer, 2017, v. 141, n. 5, p. 877, doi. 10.1002/ijc.30828
    By:
    • Horak, Peter;
    • Klink, Barbara;
    • Heining, Christoph;
    • Gröschel, Stefan;
    • Hutter, Barbara;
    • Fröhlich, Martina;
    • Uhrig, Sebastian;
    • Hübschmann, Daniel;
    • Schlesner, Matthias;
    • Eils, Roland;
    • Richter, Daniela;
    • Pfütze, Katrin;
    • Geörg, Christina;
    • Meißburger, Bettina;
    • Wolf, Stephan;
    • Schulz, Angela;
    • Penzel, Roland;
    • Herpel, Esther;
    • Kirchner, Martina;
    • Lier, Amelie
    Publication type:
    Article
    10

    Whole genome sequencing puts forward hypotheses on metastasis evolution and therapy in colorectal cancer.

    Published in:
    Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-07041-z
    By:
    • Ishaque, Naveed;
    • Abba, Mohammed L.;
    • Hauser, Christine;
    • Patil, Nitin;
    • Paramasivam, Nagarajan;
    • Huebschmann, Daniel;
    • Leupold, Jörg Hendrik;
    • Balasubramanian, Gnana Prakash;
    • Kleinheinz, Kortine;
    • Toprak, Umut H.;
    • Hutter, Barbara;
    • Benner, Axel;
    • Shavinskaya, Anna;
    • Zhou, Chan;
    • Gu, Zuguang;
    • Kerssemakers, Jules;
    • Marx, Alexander;
    • Moniuszko, Marcin;
    • Kozlowski, Miroslaw;
    • Reszec, Joanna
    Publication type:
    Article
    11

    ZygosityPredictor.

    Published in:
    Bioinformatics Advances, 2024, v. 4, n. 1, p. 1, doi. 10.1093/bioadv/vbae017
    By:
    • Rheinnecker, Marco;
    • Fröhlich, Martina;
    • Rübsam, Marc;
    • Paramasivam, Nagarajan;
    • Heilig, Christoph E;
    • Fröhling, Stefan;
    • Schlenk, Richard F;
    • Hutter, Barbara;
    • Hübschmann, Daniel
    Publication type:
    Article
    12

    Framework for quality assessment of whole genome cancer sequences.

    Published in:
    Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-18688-y
    By:
    • Whalley, Justin P.;
    • Buchhalter, Ivo;
    • Rheinbay, Esther;
    • Raine, Keiran M.;
    • Stobbe, Miranda D.;
    • Kleinheinz, Kortine;
    • Werner, Johannes;
    • Beltran, Sergi;
    • Gut, Marta;
    • Hübschmann, Daniel;
    • Hutter, Barbara;
    • Livitz, Dimitri;
    • Perry, Marc D.;
    • Rosenberg, Mara;
    • Saksena, Gordon;
    • Trotta, Jean-Rémi;
    • Eils, Roland;
    • Gerhard, Daniela S.;
    • Campbell, Peter J.;
    • Schlesner, Matthias
    Publication type:
    Article
    13

    The landscape of chromothripsis across adult cancer types.

    Published in:
    Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-16134-7
    By:
    • Voronina, Natalia;
    • Wong, John K. L.;
    • Hübschmann, Daniel;
    • Hlevnjak, Mario;
    • Uhrig, Sebastian;
    • Heilig, Christoph E.;
    • Horak, Peter;
    • Kreutzfeldt, Simon;
    • Mock, Andreas;
    • Stenzinger, Albrecht;
    • Hutter, Barbara;
    • Fröhlich, Martina;
    • Brors, Benedikt;
    • Jahn, Arne;
    • Klink, Barbara;
    • Gieldon, Laura;
    • Sieverling, Lina;
    • Feuerbach, Lars;
    • Chudasama, Priya;
    • Beck, Katja
    Publication type:
    Article
    14
    15

    Targetable ERBB2 mutations identified in neurofibroma/schwannoma hybrid nerve sheath tumors.

    Published in:
    2020
    By:
    • Ronellenfitsch, Michael W.;
    • Harter, Patrick N.;
    • Kirchner, Martina;
    • Heining, Christoph;
    • Hutter, Barbara;
    • Gieldon, Laura;
    • Schittenhelm, Jens;
    • Schuhmann, Martin U.;
    • Tatagiba, Marcos;
    • Marquardt, Gerhard;
    • Wagner, Marlies;
    • Endris, Volker;
    • Brandts, Christian H.;
    • Mautner, Victor-Felix;
    • Schröck, Evelin;
    • Weichert, Wilko;
    • Brors, Benedikt;
    • von Deimling, Andreas;
    • Mittelbronn, Michel;
    • Steinbach, Joachim P.
    Publication type:
    journal article
    16
    17

    BRAF inhibitor--associated ERK activation drives development of chronic lymphocytic leukemia.

    Published in:
    Journal of Clinical Investigation, 2014, v. 124, n. 11, p. 5074, doi. 10.1172/JCI76539
    By:
    • Yaktapour, Niuscha;
    • Meiss, Frank;
    • Mastroianni, Justin;
    • Zenz, Thorsten;
    • Andrlova, Hana;
    • Mathew, Nimitha R.;
    • Claus, Rainer;
    • Hutter, Barbara;
    • Fröhling, Stefan;
    • Brors, Benedikt;
    • Pfeifer, Dietmar;
    • Pantic, Milena;
    • Bartsch, Ingrid;
    • Spehl, Timo S.;
    • Meyer, Philipp T.;
    • Duyster, Justus;
    • Zirlik, Katja;
    • Brummer, Tilman;
    • Zeiser, Robert
    Publication type:
    Article
    18

    Germline SDHB‐inactivating mutation in gastric spindle cell sarcoma.

    Published in:
    Genes, Chromosomes & Cancer, 2020, v. 59, n. 10, p. 601, doi. 10.1002/gcc.22876
    By:
    • Heilig, Christoph E.;
    • Horak, Peter;
    • Lipka, Daniel B.;
    • Mock, Andreas;
    • Uhrig, Sebastian;
    • Kreutzfeldt, Simon;
    • Richter, Susan;
    • Gieldon, Laura;
    • Fröhlich, Martina;
    • Hutter, Barbara;
    • Hübschmann, Daniel;
    • Teleanu, Veronica;
    • Schmier, Johann‐Wilhelm;
    • Philipzen, Johannes;
    • Beuthien‐Baumann, Bettina;
    • Schröck, Evelin;
    • Deimling, Andreas;
    • Bauer, Sebastian;
    • Heining, Christoph;
    • Mechtersheimer, Gunhild
    Publication type:
    Article
    19

    Integrating proteomics into precision oncology.

    Published in:
    International Journal of Cancer, 2021, v. 148, n. 6, p. 1438, doi. 10.1002/ijc.33301
    By:
    • Wahjudi, Leonie W.;
    • Bernhardt, Stephan;
    • Abnaof, Khalid;
    • Horak, Peter;
    • Kreutzfeldt, Simon;
    • Heining, Christoph;
    • Borgoni, Simone;
    • Becki, Corinna;
    • Berg, Daniela;
    • Richter, Daniela;
    • Hutter, Barbara;
    • Uhrig, Sebastian;
    • Pfütze, Katrin;
    • Leichsenring, Jonas;
    • Glimm, Hanno;
    • Brors, Benedikt;
    • Kalle, Christof;
    • Stenzinger, Albrecht;
    • Korf, Ulrike;
    • Fröhling, Stefan
    Publication type:
    Article
    20

    Variant classification in precision oncology.

    Published in:
    International Journal of Cancer, 2019, v. 145, n. 11, p. 2996, doi. 10.1002/ijc.32358
    By:
    • Leichsenring, Jonas;
    • Horak, Peter;
    • Kreutzfeldt, Simon;
    • Heining, Christoph;
    • Christopoulos, Petros;
    • Volckmar, Anna‐Lena;
    • Neumann, Olaf;
    • Kirchner, Martina;
    • Ploeger, Carolin;
    • Budczies, Jan;
    • Heilig, Christoph E.;
    • Hutter, Barbara;
    • Fröhlich, Martina;
    • Uhrig, Sebastian;
    • Kazdal, Daniel;
    • Allgäuer, Michael;
    • Harms, Alexander;
    • Rempel, Eugen;
    • Lehmann, Ulrich;
    • Thomas, Michael
    Publication type:
    Article
    21

    A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing.

    Published in:
    Nature Communications, 2015, v. 6, n. 12, p. 10001, doi. 10.1038/ncomms10001
    By:
    • Alioto, Tyler S.;
    • Buchhalter, Ivo;
    • Derdak, Sophia;
    • Hutter, Barbara;
    • Eldridge, Matthew D.;
    • Hovig, Eivind;
    • Heisler, Lawrence E.;
    • Beck, Timothy A.;
    • Simpson, Jared T.;
    • Tonon, Laurie;
    • Sertier, Anne-Sophie;
    • Patch, Ann-Marie;
    • Jäger, Natalie;
    • Ginsbach, Philip;
    • Drews, Ruben;
    • Paramasivam, Nagarajan;
    • Kabbe, Rolf;
    • Chotewutmontri, Sasithorn;
    • Diessl, Nicolle;
    • Previti, Christopher
    Publication type:
    Article
    22
    23

    Genomic footprints of activated telomere maintenance mechanisms in cancer.

    Published in:
    Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-019-13824-9
    By:
    • Sieverling, Lina;
    • Hong, Chen;
    • Koser, Sandra D.;
    • Ginsbach, Philip;
    • Kleinheinz, Kortine;
    • Hutter, Barbara;
    • Braun, Delia M.;
    • Cortés-Ciriano, Isidro;
    • Xi, Ruibin;
    • Kabbe, Rolf;
    • Park, Peter J.;
    • Eils, Roland;
    • Schlesner, Matthias;
    • PCAWG-Structural Variation Working Group;
    • Akdemir, Kadir C.;
    • Alvarez, Eva G.;
    • Baez-Ortega, Adrian;
    • Beroukhim, Rameen;
    • Boutros, Paul C.;
    • Bowtell, David D. L.
    Publication type:
    Article
    24

    Defective homologous recombination DNA repair as therapeutic target in advanced chordoma.

    Published in:
    Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-09633-9
    By:
    • Gröschel, Stefan;
    • Hübschmann, Daniel;
    • Raimondi, Francesco;
    • Horak, Peter;
    • Warsow, Gregor;
    • Fröhlich, Martina;
    • Klink, Barbara;
    • Gieldon, Laura;
    • Hutter, Barbara;
    • Kleinheinz, Kortine;
    • Bonekamp, David;
    • Marschal, Oliver;
    • Chudasama, Priya;
    • Mika, Jagoda;
    • Groth, Marie;
    • Uhrig, Sebastian;
    • Krämer, Stephen;
    • Heining, Christoph;
    • Heilig, Christoph E.;
    • Richter, Daniela
    Publication type:
    Article
    25

    Successful BRAF/MEK inhibition in a patient with BRAF<sup>V600E</sup>-mutated extrapancreatic acinar cell carcinoma.

    Published in:
    Cold Spring Harbor Molecular Case Studies, 2020, v. 6, n. 4, p. 1, doi. 10.1101/mcs.a005553
    By:
    • Busch, Elena;
    • Kreutzfeldt, Simon;
    • Agaimy, Abbas;
    • Mechtersheimer, Gunhild;
    • Horak, Peter;
    • Brors, Benedikt;
    • Hutter, Barbara;
    • Fröhlich, Martina;
    • Uhrig, Sebastian;
    • Mayer, Philipp;
    • Schröck, Evelin;
    • Stenzinger, Albrecht;
    • Glimm, Hanno;
    • Jäger, Dirk;
    • Springfeld, Christoph;
    • Fröhling, Stefan;
    • Zschäbitz, Stefanie
    Publication type:
    Article
    26
    27

    TelomereHunter – in silico estimation of telomere content and composition from cancer genomes.

    Published in:
    BMC Bioinformatics, 2019, v. 20, n. 1, p. 1, doi. 10.1186/s12859-019-2851-0
    By:
    • Feuerbach, Lars;
    • Sieverling, Lina;
    • Deeg, Katharina I.;
    • Ginsbach, Philip;
    • Hutter, Barbara;
    • Buchhalter, Ivo;
    • Northcott, Paul A.;
    • Mughal, Sadaf S.;
    • Chudasama, Priya;
    • Glimm, Hanno;
    • Scholl, Claudia;
    • Lichter, Peter;
    • Fröhling, Stefan;
    • Pfister, Stefan M.;
    • Jones, David T. W.;
    • Rippe, Karsten;
    • Brors, Benedikt
    Publication type:
    Article
    28

    Dissecting the genomic complexity underlying medulloblastoma.

    Published in:
    Nature, 2012, v. 488, n. 7409, p. 100, doi. 10.1038/nature11284
    By:
    • Jones, David T. W.;
    • Jäger, Natalie;
    • Kool, Marcel;
    • Zichner, Thomas;
    • Hutter, Barbara;
    • Sultan, Marc;
    • Cho, Yoon-Jae;
    • Pugh, Trevor J.;
    • Hovestadt, Volker;
    • Stütz, Adrian M.;
    • Rausch, Tobias;
    • Warnatz, Hans-Jörg;
    • Ryzhova, Marina;
    • Bender, Sebastian;
    • Sturm, Dominik;
    • Pleier, Sabrina;
    • Cin, Huriye;
    • Pfaff, Elke;
    • Sieber, Laura;
    • Wittmann, Andrea
    Publication type:
    Article
    29

    Combining transcription factor binding affinities with open-chromatin data for accurate gene expression prediction.

    Published in:
    Nucleic Acids Research, 2017, v. 45, n. 1, p. 54, doi. 10.1093/nar/gkw1061
    By:
    • Schmidt, Florian;
    • Gasparoni, Nina;
    • Gasparoni, Gilles;
    • Gianmoena, Kathrin;
    • Cadenas, Cristina;
    • Polansky, Julia K.;
    • Ebert, Peter;
    • Barann, Matthias;
    • Sinha, Anupam;
    • Fröhler, Sebastian;
    • Jieyi Xiong;
    • Amirabad, Azim Dehghani;
    • Ardakani, Fatemeh Behjati;
    • Hutter, Barbara;
    • Zipprich, Gideon;
    • Felder, Bärbel;
    • Eils, Jürgen;
    • Brors, Benedikt;
    • Wei Chen;
    • Hengstler, Jan G.
    Publication type:
    Article
    30