Works by Hurst, Jose

Results: 39

Ex vivo biophysical characterization of a hydrogel-based artificial vitreous substitute.

Published in:

PLoS ONE, 2019, v. 14, n. 01, p. 1, doi. 10.1371/journal.pone.0209217

By:

Januschowski, Kai;
Schnichels, Sven;
Hurst, José;
Hohenadl, Christine;
Reither, Charlotte;
Rickmann, Annekatrin;
Pohl, Lisa;
Bartz-Schmidt, Karl-Ulrich;
Spitzer, Martin S.

Publication type:

Article

Introducing a Porcine Inflammatory Ex Vivo Retina Model for Diabetic Retinopathy.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 8, p. 3919, doi. 10.3390/ijms26083919

By:

Mühle, Agnes;
Schnichels, Sven;
Hurst, José

Publication type:

Article

Co-cultivation of primary porcine RPE cells and neuroretina induces inflammation: a potential inflammatory AMD-model.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-46029-8

By:

Fietz, Agnes;
Schnichels, Sven;
Hurst, José

Publication type:

Article

Can SARS-CoV-2 infect the eye? An overview of the receptor status in ocular tissue.

Published in:

Der Ophthalmologe, 2021, v. 118, p. 81, doi. 10.1007/s00347-020-01281-5

By:

Schnichels, Sven;
Rohrbach, Jens Martin;
Bayyoud, Tarek;
Thaler, Sebastian;
Ziemssen, Focke;
Hurst, José

Publication type:

Article

Kann SARS-CoV-2 das Auge infizieren? – Ein Überblick über den Rezeptorstatus in okularem Gewebe.

Published in:

Der Ophthalmologe, 2020, v. 117, n. 7, p. 618, doi. 10.1007/s00347-020-01160-z

By:

Schnichels, Sven;
Rohrbach, Jens Martin;
Bayyoud, Tarek;
Thaler, Sebastian;
Ziemssen, Focke;
Hurst, José

Publication type:

Article

Efficacy of two different thiol-modified crosslinked hyaluronate formulations as vitreous replacement compared to silicone oil in a model of retinal detachment.

Published in:

PLoS ONE, 2017, v. 12, n. 3, p. 1, doi. 10.1371/journal.pone.0172895

By:

Schnichels, Sven;
Schneider, Nele;
Hohenadl, Christine;
Hurst, José;
Schatz, Andreas;
Januschowski, Kai;
Spitzer, Martin S.

Publication type:

Article

Editorial: Brain vs. retina - Dierences and commonalities: The role of oxidative stress in neurodegenerative diseases ..

Published in:

Frontiers in Neuroscience, 2023, v. 17, p. 1, doi. 10.3389/fnins.2023.1171235

By:

Hurst, José;
Schnichels, Sven

Publication type:

Article

The function of p53 and its role in Alzheimer's and Parkinson's disease compared to age-related macular degeneration.

Published in:

Frontiers in Neuroscience, 2022, v. 16, p. 1, doi. 10.3389/fnins.2022.1029473

By:

Wolfrum, Peter;
Fietz, Agnes;
Schnichels, Sven;
Hurst, José

Publication type:

Article

Retinal Organ Cultures as Alternative Research Models.

Published in:

Alternatives to Laboratory Animals, 2019, v. 47, n. 1, p. 19, doi. 10.1177/0261192919840092

By:

Schnichels, Sven;
Kiebler, Tobias;
Hurst, José;
Maliha, Ana M.;
Löscher, Marina;
Dick, H. Burkhard;
Bartz-Schmidt, Karl-Ulrich;
Joachim, Stephanie C.

Publication type:

Article

A Novel Porcine Ex Vivo Retina Culture Model for Oxidative Stress Induced by H<sub>2</sub>O<sub>2</sub>.

Published in:

Alternatives to Laboratory Animals, 2017, v. 45, n. 1, p. 11, doi. 10.1177/026119291704500105

By:

Hurst, José;
Kuehn, Sandra;
Jashari, Adelina;
Tsai, Teresa;
Bartz-Schmidt, Karl Ulrich;
Schnichels, Sven;
Joachim, Stephanie C.

Publication type:

Article

The Novel Induction of Retinal Ganglion Cell Apoptosis in Porcine Organ Culture by NMDA -- An Opportunity for the Replacement of Animals in Experiments.

Published in:

Alternatives to Laboratory Animals, 2016, v. 44, n. 6, p. 557, doi. 10.1177/026119291604400608

By:

Kuehn, Sandra;
Hurst, Jose;
Jashari, Adelina;
Ahrens, Kathrin;
Tsai, Teresa;
Wunderlich, Ilan M.;
Dick, H. Burkhard;
Joachim, Stephanie C.;
Schnichels, Sven

Publication type:

Article

Oxidative stress‐induced retinal damage is prevented by mild hypothermia in an ex vivo model of cultivated porcine retinas.

Published in:

Clinical & Experimental Ophthalmology, 2020, v. 48, n. 5, p. 666, doi. 10.1111/ceo.13731

By:

Mueller‐Buehl, Ana M.;
Doepper, Hannah;
Grauthoff, Sven;
Kiebler, Tobias;
Peters, Laura;
Hurst, José;
Kuehn, Sandra;
Bartz‐Schmidt, Karl U.;
Dick, H. Burkard;
Joachim, Stephanie C.;
Schnichels, Sven

Publication type:

Article

Hypothermia protects retinal ganglion cells against hypoxia‐induced cell death in a retina organ culture model.

Published in:

Clinical & Experimental Ophthalmology, 2019, v. 47, n. 8, p. 1043, doi. 10.1111/ceo.13565

By:

Klemm, Patricia;
Hurst, José;
Dias Blak, Matthias;
Herrmann, Thoralf;
Melchinger, Marion;
Bartz‐Schmidt, Karl U.;
Zeck, Günther;
Schultheiss, Maximilian;
Spitzer, Martin S.;
Schnichels, Sven

Publication type:

Article

Novel mouse model for primary uveal melanoma: a pilot study.

Published in:

Clinical & Experimental Ophthalmology, 2017, v. 45, n. 2, p. 192, doi. 10.1111/ceo.12814

By:

Süsskind, Daniela;
Hurst, José;
Rohrbach, Jens Martin;
Schnichels, Sven

Publication type:

Article

Impact of Primary RPE Cells in a Porcine Organotypic Co-Cultivation Model.

Published in:

Biomolecules (2218-273X), 2022, v. 12, n. 7, p. N.PAG, doi. 10.3390/biom12070990

By:

Wagner, Natalie;
Safaei, Armin;
Hurst, José;
Vogt, Pia A.;
Dick, H. Burkhard;
Joachim, Stephanie C.;
Schnichels, Sven

Publication type:

Article

Reduced Retinal Degeneration in an Oxidative Stress Organ Culture Model through an iNOS-Inhibitor.

Published in:

Biology (2079-7737), 2021, v. 10, n. 5, p. 383, doi. 10.3390/biology10050383

By:

Mueller-Buehl, Ana M.;
Tsai, Teresa;
Hurst, José;
Theiss, Carsten;
Peters, Laura;
Hofmann, Lisa;
Herms, Fenja;
Kuehn, Sandra;
Schnichels, Sven;
Joachim, Stephanie C.;
Sagdullaev, Botir T.

Publication type:

Article

Two Methods for the Isolation and Cultivation of Porcine Primary Corneal Cells.

Published in:

Methods & Protocols, 2023, v. 6, n. 3, p. 50, doi. 10.3390/mps6030050

By:

Netto, Alice Rocha Teixeira;
Hrusa, Marc Dieter;
Bartz-Schmidt, Karl-Ulrich;
Schnichels, Sven;
Hurst, José

Publication type:

Article

Long-Term Biocompatibility of a Highly Viscously Thiol-Modified Cross-Linked Hyaluronate as a Novel Vitreous Body Substitute.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.817353

By:

Hurst, Jose;
Rickmann, Annekatrin;
Heider, Nele;
Hohenadl, Christine;
Reither, Charlotte;
Schatz, Andreas;
Schnichels, Sven;
Januschowski, Kai;
Spitzer, Martin S.

Publication type:

Article

Hypothermia Protects and Prolongs the Tolerance Time of Retinal Ganglion Cells against Ischemia.

Published in:

PLoS ONE, 2016, v. 11, n. 2, p. 1, doi. 10.1371/journal.pone.0148616

By:

Schultheiss, Maximilian;
Schnichels, Sven;
Hermann, Thoralf;
Hurst, Jose;
Feldkaemper, Marita;
Arango-Gonzalez, Blanca;
Ueffing, Marius;
Bartz-Schmidt, Karl U.;
Zeck, Guenther;
Spitzer, Martin S.

Publication type:

Article

iNOS‐inhibitor driven neuroprotection in a porcine retina organ culture model.

Published in:

Journal of Cellular & Molecular Medicine, 2020, v. 24, n. 7, p. 4312, doi. 10.1111/jcmm.15091

By:

Hurst, José;
Mueller‐Buehl, Ana Maria;
Hofmann, Lisa;
Kuehn, Sandra;
Herms, Fenja;
Schnichels, Sven;
Joachim, Stephanie Christine

Publication type:

Article

Diminished apoptosis in hypoxic porcine retina explant cultures through hypothermia.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-41113-4

By:

Maliha, Ana M.;
Kuehn, Sandra;
Hurst, José;
Herms, Fenja;
Fehr, Michael;
Bartz-Schmidt, Karl U.;
Dick, H. Burkhard;
Joachim, Stephanie C.;
Schnichels, Sven

Publication type:

Article

Comparison of Different Cell Culture Media in the Model of the Isolated and Superfused Bovine Retina: Investigating the Limits of More Physiological Perfusion Solutions.

Published in:

Current Eye Research, 2018, v. 43, n. 2, p. 232, doi. 10.1080/02713683.2017.1387668

By:

Hurst, José;
Vitkute, Milda;
Hofmann, Kathleen;
Müller, Sebastian;
Löscher, Marina;
Bartz-Schmidt, Karl-Ulrich;
Spitzer, Martin S;
Schnichels, Sven;
Januschowski, Kai

Publication type:

Article

Characterization of a Standardized Ex-vivo Porcine Model to Assess Short Term Intraocular Pressure Changes and Trabecular Meshwork Vitality After Pars Plana Vitrectomy with Different Silicone Oil and BSS Tamponades.

Published in:

Current Eye Research, 2017, v. 42, n. 8, p. 1130, doi. 10.1080/02713683.2017.1297461

By:

Ebner, Martina;
Mariacher, Siegfried;
Hurst, José;
Szurman, Peter;
Schnichels, Sven;
Spitzer, Martin S.;
Januschowski, Kai

Publication type:

Article

Negative Effects of Acid Violet-17 and MBB Dual In Vitro on Different Ocular Cell Lines.

Published in:

Current Eye Research, 2017, v. 42, n. 8, p. 1209, doi. 10.1080/02713683.2017.1285942

By:

Hurst, José;
Schnichels, Sven;
Spitzer, Martin S.;
Bartz-Schmidt, Karl-Ulrich;
Farecki, Marie-Louise;
Szurman, Peter;
Januschowski, Kai

Publication type:

Article

Effects of mesenchymal stromal cells and human recombinant Nerve Growth Factor delivered by bioengineered human corneal lenticule on an innovative model of diabetic retinopathy.

Published in:

Frontiers in Endocrinology, 2024, p. 01, doi. 10.3389/fendo.2024.1462043

By:

Pelusi, Letizia;
Hurst, Jose;
Detta, Nicola;
Pipino, Caterina;
Lamolinara, Alessia;
Conte, Gemma;
Mastropasqua, Rodolfo;
Allegretti, Marcello;
Di Pietrantonio, Nadia;
Romeo, Tiziana;
El Zarif, Mona;
Nubile, Mario;
Guerricchio, Laura;
Bollini, Sveva;
Pandolfi, Assunta;
Schnichels, Sven;
Mandatori, Domitilla

Publication type:

Article

Organ Cultures for Retinal Diseases.

Published in:

Frontiers in Neuroscience, 2020, v. 14, p. N.PAG, doi. 10.3389/fnins.2020.583392

By:

Hurst, José;
Fietz, Agnes;
Tsai, Teresa;
Joachim, Stephanie C.;
Schnichels, Sven

Publication type:

Article

Novel Porcine Retina Cultivation Techniques Provide Improved Photoreceptor Preservation.

Published in:

Frontiers in Neuroscience, 2020, v. 14, p. N.PAG, doi. 10.3389/fnins.2020.556700

By:

Wagner, Natalie;
Reinehr, Sabrina;
Gammel, Maurice R.;
Greulich, Andrea;
Hurst, José;
Dick, H. Burkhard;
Schnichels, Sven;
Joachim, Stephanie C.

Publication type:

Article

A Case Study from the Past: "The RGC-5 vs. the 661W Cell Line: Similarities, Differences and Contradictions—Are They Really the Same?".

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 18, p. 13801, doi. 10.3390/ijms241813801

By:

Hurst, José;
Attrodt, Gesine;
Bartz-Schmidt, Karl-Ulrich;
Mau-Holzmann, Ulrike Angelika;
Spitzer, Martin Stephan;
Schnichels, Sven

Publication type:

Article

Out of the Shadow: Blue Light Exposure Induces Apoptosis in Müller Cells.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 23, p. 14540, doi. 10.3390/ijms232314540

By:

Fietz, Agnes;
Hurst, José;
Schnichels, Sven

Publication type:

Article

Porcine Corneas Incubated at Low Humidity Present Characteristic Features Found in Dry Eye Disease.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 9, p. 4567, doi. 10.3390/ijms23094567

By:

Netto, Alice Rocha Teixeira;
Hurst, José;
Bartz-Schmidt, Karl-Ulrich;
Schnichels, Sven

Publication type:

Article

Cyclosporine A Protects Retinal Explants against Hypoxia.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 19, p. 10196, doi. 10.3390/ijms221910196

By:

Schnichels, Sven;
Schultheiss, Maximilian;
Klemm, Patricia;
Blak, Matthias;
Herrmann, Thoralf;
Melchinger, Marion;
Bartz-Schmidt, Karl-Ulrich;
Löscher, Marina;
Zeck, Günther;
Spitzer, Martin Stehphan;
Hurst, José

Publication type:

Article

The Future of Nanomaterials Tackling the Challenge of Delivering Nucleic Acids to the Retina.

Published in:

Advanced Functional Materials, 2025, v. 35, n. 3, p. 1, doi. 10.1002/adfm.202407173

By:

Hurst, José;
Adams, Friederike;
Schnichels, Sven

Publication type:

Article

Degradable and Biocompatible Magnesium Zinc Structures for Nanomedicine: Magnetically Actuated Liposome Microcarriers with Tunable Release.

Published in:

Advanced Functional Materials, 2024, v. 34, n. 23, p. 1, doi. 10.1002/adfm.202314265

By:

Peter, Florian;
Kadiri, Vincent Mauricio;
Goyal, Rahul;
Hurst, José;
Schnichels, Sven;
Avital, Aviram;
Sela, Mor;
Mora‐Raimundo, Patricia;
Schroeder, Avi;
Alarcón‐Correa, Mariana;
Fischer, Peer

Publication type:

Article

Lipid-DNA Nanoparticles as Drug-Delivery Vehicles for the Treatment of Retinal Diseases.

Published in:

Pharmaceutics, 2023, v. 15, n. 2, p. 532, doi. 10.3390/pharmaceutics15020532

By:

Schnichels, Sven;
Simmang, David;
Löscher, Marina;
Herrmann, Andreas;
de Vries, Jan Willem;
Spitzer, Martin S.;
Hurst, José

Publication type:

Article

Topical Drug Delivery to the Posterior Segment of the Eye.

Published in:

Pharmaceutics, 2022, v. 14, n. 1, p. 134, doi. 10.3390/pharmaceutics14010134

By:

Löscher, Marina;
Seiz, Chiara;
Hurst, José;
Schnichels, Sven

Publication type:

Article

The Effect of mPEGA/EHA Ratio and Copolymer Composition on the Solution Behavior of Amphiphilic, Comb‐Shape Copolymers Synthesized via Cu(0)‐Mediated SET‐LRP for Potential Drug Delivery Applications.

Published in:

Macromolecular Chemistry & Physics, 2023, v. 224, n. 24, p. 1, doi. 10.1002/macp.202300226

By:

Pourdakheli Hamedani, Yasaman;
Çakırefe, Semanur;
Fietz, Agnes;
Hurst, José;
Schnichels, Sven;
Adams, Friederike

Publication type:

Article

Blue Light Damage and p53: Unravelling the Role of p53 in Oxidative-Stress-Induced Retinal Apoptosis.

Published in:

Antioxidants, 2023, v. 12, n. 12, p. 2072, doi. 10.3390/antiox12122072

By:

Fietz, Agnes;
Corsi, Francesca;
Hurst, José;
Schnichels, Sven

Publication type:

Article

Decellularized human corneal lenticule as a delivery system of recombinant human nerve growth factor and human amniotic fluid stem cells factors for posterior ocular disease treatment.

Published in:

Acta Ophthalmologica (1755375X), 2024, v. 102, p. N.PAG, doi. 10.1111/aos.15999

By:

Mandatori, Domitilla;
Pelusi, Letizia;
Ghelardoni, Maddalena;
Agnifili, Luca;
Di Pietrantonio, Nadia;
Hurst, Jose;
Allegretti, Marcello;
Schnichels, Sven;
Mastropasqua, Leonardo;
Bollini, Sveva;
Nubile, Mario;
Pandolfi, Assunta

Publication type:

Article

Porcine ex vivo retina model to study retinal neurodegenerative diseases: Potential role of mesenchymal stem cells.

Published in:

Acta Ophthalmologica (1755375X), 2024, v. 102, p. N.PAG, doi. 10.1111/aos.15901

By:

Pelusi, Letizia;
Ghelardoni, Maddalena;
Agnifili, Luca;
Cappellacci, Ilaria;
Allegretti, Marcello;
Hurst, Jose;
Schnichels, Sven;
Mastropasqua, Leonardo;
Bollini, Sveva;
Nubile, Mario;
Pandolfi, Assunta;
Mandatori, Domitilla

Publication type:

Article