Works matching AU Hunter, Dominic J. B.

Results: 15

Selectivity of Lewy body protein interactions along the aggregation pathway of α-synuclein.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02624-x

By:

Leitão, André D. G.;
Rudolffi-Soto, Paulina;
Chappard, Alexandre;
Bhumkar, Akshay;
Lau, Derrick;
Hunter, Dominic J. B.;
Gambin, Yann;
Sierecki, Emma

Publication type:

Article

Assembly of an Oxo–Zirconium(IV) Cluster in a Protein CleftWe thank The Wellcome Trust (Travelling Research Fellowship and International Research Development Award for WZ, Sir Henry Wellcome Commemorative Award for DJC and PJS, and Edinburgh Protein Interaction Centre), The Darwin Trust, CCLRC, EPSRC, Royal Society, Wolfson Foundation and the Medical Science Foundation of Chinese PLA (grant No. 01H021 for WZ) for their support for this work, and Dr Lorna Eades and John Wexler for assistance with ICP-MS and graphics, respectively.

Published in:

Angewandte Chemie International Edition, 2004, v. 43, n. 44, p. 5914, doi. 10.1002/anie.200460806

By:

Weiqing Zhong;
Dmitriy Alexeev;
Ian Harvey;
Maolin Guo;
Dominic J. B. Hunter;
Haizhong Zhu;
Dominic J. Campopiano;
Peter J. Sadler

Publication type:

Article

Engineering Thermostable CYP2D Enzymes for Biocatalysis Using Combinatorial Libraries of Ancestors for Directed Evolution (CLADE).

Published in:

ChemCatChem, 2019, v. 11, n. 2, p. 841, doi. 10.1002/cctc.201801644

By:

Gumulya, Yosephine;
Huang, Weiliang;
D'Cunha, Stephlina A.;
Richards, Katelyn E.;
Thomson, Raine E. S.;
Hunter, Dominic J. B.;
Baek, Jong‐Min;
Harris, Kurt L.;
Boden, M.;
De Voss, James J.;
Hayes, Martin A.;
Isin, Emre M.;
Andersson, Shalini;
Jurva, Ulrik;
Gillam, Elizabeth M. J.

Publication type:

Article

Rational evolution of the cofactor‐binding site of cytochrome P450 reductase yields variants with increased activity towards specific cytochrome P450 enzymes.

Published in:

FEBS Journal, 2019, v. 286, n. 22, p. 4473, doi. 10.1111/febs.14982

By:

Strohmaier, Silja J.;
Huang, Weiliang;
Baek, Jong‐Min;
Hunter, Dominic J. B.;
Gillam, Elizabeth M. J.

Publication type:

Article

MyD88 TIR domain higher-order assembly interactions revealed by microcrystal electron diffraction and serial femtosecond crystallography.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-22590-6

By:

Clabbers, Max T. B.;
Holmes, Susannah;
Muusse, Timothy W.;
Vajjhala, Parimala R.;
Thygesen, Sara J.;
Malde, Alpeshkumar K.;
Hunter, Dominic J. B.;
Croll, Tristan I.;
Flueckiger, Leonie;
Nanson, Jeffrey D.;
Rahaman, Md. Habibur;
Aquila, Andrew;
Hunter, Mark S.;
Liang, Mengning;
Yoon, Chun Hong;
Zhao, Jingjing;
Zatsepin, Nadia A.;
Abbey, Brian;
Sierecki, Emma;
Gambin, Yann

Publication type:

Article

Pathological mutations differentially affect the self-assembly and polymerisation of the innate immune system signalling adaptor molecule MyD88.

Published in:

BMC Biology, 2018, v. 16, n. 1, p. 1, doi. 10.1186/s12915-018-0611-7

By:

O'Carroll, Ailís;
Chauvin, Brieuc;
Brown, James W. P.;
Meagher, Ava;
Coyle, Joanne;
Schill, Jurgen;
Bhumkhar, Akshay;
Hunter, Dominic J. B.;
Ve, Thomas;
Kobe, Bostjan;
Sierecki, Emma;
Gambin, Yann

Publication type:

Article

Cell-free formation and interactome analysis of caveolae.

Published in:

Journal of Cell Biology, 2018, v. 217, n. 6, p. 2141, doi. 10.1083/jcb.201707004

By:

WooRam Jung;
Sierecki, Emma;
Bastiani, Michele;
O’Carroll, Ailis;
Alexandrov, Kirill;
Rae, James;
Johnston, Wayne;
Hunter, Dominic J. B.;
Ferguson, Charles;
Gambin, Yann;
Ariotti, Nicholas;
Parton, Robert G.

Publication type:

Article

Homodimerization regulates an endothelial specific signature of the SOX18 transcription factor.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 21, p. 11381, doi. 10.1093/nar/gky897

By:

Moustaqil, Mehdi;
Fontaine, Frank;
Overman, Jeroen;
McCann, Alex;
Bailey, Timothy L;
Rudolffi Soto, Paulina;
Bhumkar, Akshay;
Giles, Nichole;
Hunter, Dominic J B;
Gambin, Yann

Publication type:

Article

Single-molecule detection on a portable 3D-printed microscope.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-13617-0

By:

Brown, James W. P.;
Bauer, Arnaud;
Polinkovsky, Mark E;
Bhumkar, Akshay;
Hunter, Dominic J. B.;
Gaus, Katharina;
Sierecki, Emma;
Gambin, Yann

Publication type:

Article

Unveiling a Selective Mechanism for the Inhibition of α-Synuclein Aggregation by β-Synuclein.

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 2, p. 334, doi. 10.3390/ijms19020334

By:

Leitao, Andre;
Bhumkar, Akshay;
Hunter, Dominic J. B.;
Gambin, Yann;
Sierecki, Emma

Publication type:

Article

A Split-Luciferase Reporter Recognizing GFP and mCherry Tags to Facilitate Studies of Protein-Protein Interactions.

Published in:

International Journal of Molecular Sciences, 2017, v. 18, n. 12, p. 2681, doi. 10.3390/ijms18122681

By:

Moustaqil, Mehdi;
Bhumkar, Akshay;
Gonzalez, Laura;
Raoul, Lisa;
Hunter, Dominic J. B.;
Carrive, Pascal;
Sierecki, Emma;
Gambin, Yann

Publication type:

Article

SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species.

Published in:

Emerging Microbes & Infections, 2021, v. 10, n. 1, p. 178, doi. 10.1080/22221751.2020.1870414

By:

Moustaqil, Mehdi;
Ollivier, Emma;
Chiu, Hsin-Ping;
Van Tol, Sarah;
Rudolffi-Soto, Paulina;
Stevens, Christian;
Bhumkar, Akshay;
Hunter, Dominic J. B.;
Freiberg, Alexander N.;
Jacques, David;
Lee, Benhur;
Sierecki, Emma;
Gambin, Yann

Publication type:

Article

Interactions of D-amphetamine with the active site of monoamine oxidase-A.

Published in:

Inflammopharmacology, 2003, v. 11, n. 2, p. 127, doi. 10.1163/156856003765764290

By:

Ramsay, Rona R.;
Hunter, Dominic J. B.

Publication type:

Article

Assembly of an Oxo–Zirconium(IV) Cluster in a Protein CleftWe thank The Wellcome Trust (Travelling Research Fellowship and International Research Development Award for WZ, Sir Henry Wellcome Commemorative Award for DJC and PJS, and Edinburgh Protein Interaction Centre), The Darwin Trust, CCLRC, EPSRC, Royal Society, Wolfson Foundation and the Medical Science Foundation of Chinese PLA (grant No. 01H021 for WZ) for their support for this work, and Dr Lorna Eades and John Wexler for assistance with ICP-MS and graphics, respectively.

Published in:

Angewandte Chemie, 2004, v. 116, n. 44, p. 6040, doi. 10.1002/ange.200460806

By:

Weiqing Zhong;
Dmitriy Alexeev;
Ian Harvey;
Maolin Guo;
Dominic J. B. Hunter;
Haizhong Zhu;
Dominic J. Campopiano;
Peter J. Sadler

Publication type:

Article

Unexpected instabilities explain batch‐to‐batch variability in cell‐free protein expression systems.

Published in:

Biotechnology & Bioengineering, 2018, v. 115, n. 8, p. 1904, doi. 10.1002/bit.26604

By:

Hunter, Dominic J. B.;
Bhumkar, Akshay;
Giles, Nichole;
Sierecki, Emma;
Gambin, Yann

Publication type:

Article