Found: 53
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Hymecromone Promotes Longevity and Insulin Sensitivity in Mice.
- Published in:
- Cells (2073-4409), 2024, v. 13, n. 20, p. 1727, doi. 10.3390/cells13201727
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- Publication type:
- Article
The islet tissue plasminogen activator/plasmin system is upregulated with human islet amyloid polypeptide aggregation and protects beta cells from aggregation-induced toxicity.
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- Diabetologia, 2024, v. 67, n. 9, p. 1897, doi. 10.1007/s00125-024-06161-0
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- Publication type:
- Article
Islet amyloid polypeptide aggregation exerts cytotoxic and proinflammatory effects on the islet vasculature in mice.
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- Diabetologia, 2022, v. 65, n. 10, p. 1687, doi. 10.1007/s00125-022-05756-9
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- Article
Low concentration IL-1β promotes islet amyloid formation by increasing hIAPP release from humanised mouse islets in vitro.
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- Diabetologia, 2020, v. 63, n. 11, p. 2385, doi. 10.1007/s00125-020-05232-2
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- Publication type:
- Article
A tale of two pancreases: exocrine pathology and endocrine dysfunction.
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- Diabetologia, 2020, v. 63, n. 10, p. 2030, doi. 10.1007/s00125-020-05210-8
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- Publication type:
- Article
Use of the PET ligand florbetapir for in vivo imaging of pancreatic islet amyloid deposits in hIAPP transgenic mice.
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- Diabetologia, 2018, v. 61, n. 10, p. 2215, doi. 10.1007/s00125-018-4695-y
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- Publication type:
- Article
Islet Amyloid: A Critical Entity in the Pathogenesis of Type 2 Diabetes.
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- Journal of Clinical Endocrinology & Metabolism, 2004, v. 89, n. 8, p. 3629, doi. 10.1210/jc.2004-0405
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- Publication type:
- Article
Cystic fibrosis-related diabetes is associated with reduced islet protein expression of GLP-1 receptor and perturbation of cell-specific transcriptional programs.
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- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-76722-1
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- Publication type:
- Article
Pancreas and islet morphology in cystic fibrosis: clues to the etiology of cystic fibrosis-related diabetes.
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- Frontiers in Endocrinology, 2023, p. 01, doi. 10.3389/fendo.2023.1269139
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- Publication type:
- Article
Mechanisms linking obesity to insulin resistance and type 2 diabetes.
- Published in:
- Nature, 2006, v. 444, n. 7121, p. 840, doi. 10.1038/nature05482
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- Publication type:
- Article
Progressive Loss of β-Cell Function Leads to Worsening Glucose Tolerance in First-Degree Relatives of Subjects With Type 2 Diabetes.
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- Diabetes Care, 2007, v. 30, n. 3, p. 677, doi. 10.2337/dc06-1834
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- Publication type:
- Article
Gestational Diabetes Mellitus Increases the Risk of Cardiovascular Disease in Women With a Family History of Type 2 Diabetes.
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- Diabetes Care, 2006, v. 29, n. 9, p. 2078, doi. 10.2337/dc05-2482
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- Publication type:
- Article
Impact of Differences in Fasting Glucose and Glucose Tolerance on the Hyperbolic Relationship Between Insulin Sensitivity and Insulin Responses.
- Published in:
- Diabetes Care, 2006, v. 29, n. 2, p. 356, doi. 10.2337/diacare.29.02.06.dc05-1963
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- Publication type:
- Article
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes.
- Published in:
- Nature Immunology, 2010, v. 11, n. 10, p. 897, doi. 10.1038/ni.1935
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- Publication type:
- Article
Loss of perlecan heparan sulfate glycosaminoglycans lowers body weight and decreases islet amyloid deposition in human islet amyloid polypeptide transgenic mice.
- Published in:
- PEDS: Protein Engineering, Design & Selection, 2019, v. 32, n. 2, p. 95, doi. 10.1093/protein/gzz041
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- Publication type:
- Article
Inhibition of the Amyloid-Degrading Enzyme, Neprilysin, Results in Increased Amyloid in Islets from Human Islet Amyloid Polypeptide (hIAPP) Transgenic Mice.
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- Diabetes, 2007, v. 56, p. A436
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- Publication type:
- Article
Amyloid-Induced Oxidative Stress Contributes to Reduced Islet Cell Viability But Does Not Impact Insulin Secretion.
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- Diabetes, 2007, v. 56, p. A436
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- Publication type:
- Article
Amyloid Formation in Isolated Islets Is Not Associated with Endoplasmic Reticulum (ER) Stress.
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- Diabetes, 2007, v. 56, p. A435
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- Publication type:
- Article
Identification of the Amyloid-Degrading Enzyme Neprilysin in Mouse Islets and Potential Role in Islet Amyloidogenesis.
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- Diabetes, 2007, v. 56, n. 2, p. 304, doi. 10.2337/db06-0430
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- Publication type:
- Article
Long-Term Treatment With Rosiglitazone and Metformin Reduces the Extent of, but Does Not Prevent, Islet Amyloid Deposition in Mice Expressing the Gene for Human Islet Amyloid Polypeptide.
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- Diabetes, 2005, v. 54, n. 7, p. 2235, doi. 10.2337/diabetes.54.7.2235
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- Publication type:
- Article
A reduced-fat diet and aerobic exercise in Japanese Americans with impaired glucose tolerance decreases intra-abdominal fat and improves insulin sensitivity but not beta-cell function.
- Published in:
- 2005
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- Publication type:
- journal article
A Reduced-Fat Diet and Aerobic Exercise in Japanese Americans With Impaired Glucose Tolerance Decreases Intra-Abdominal Fat and Improves Insulin Sensitivity but not β-Cell Function.
- Published in:
- Diabetes, 2005, v. 54, n. 2, p. 340, doi. 10.2337/diabetes.54.2.340
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- Publication type:
- Article
Impact of intra-abdominal fat and age on insulin sensitivity and beta-cell function.
- Published in:
- 2004
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- Publication type:
- journal article
Intra-abdominal fat is a major determinant of the National Cholesterol Education Program Adult Treatment Panel III criteria for the metabolic syndrome.
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- 2004
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- Publication type:
- journal article
Increased dietary fat promotes islet amyloid formation and beta-cell secretory dysfunction in a transgenic mouse model of islet amyloid.
- Published in:
- 2003
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- Publication type:
- journal article
Beta-cell function is a major contributor to oral glucose tolerance in high-risk relatives of four ethnic groups in the U.S.
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- 2002
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- Publication type:
- journal article
β-Cell Function Is a Major Contributor to Oral Glucose Tolerance in High-Risk Relatives of Four Ethnic Groups in the U.S.
- Published in:
- Diabetes, 2002, v. 51, n. 7, p. 2170
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- Publication type:
- Article
The concurrent accumulation of intra-abdominal and subcutaneous fat explains the association between insulin resistance and plasma leptin concentrations : distinct metabolic effects of two fat compartments.
- Published in:
- 2002
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- Publication type:
- journal article
Islet amyloid develops diffusely throughout the pancreas before becoming severe and replacing endocrine cells.
- Published in:
- 2001
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- Publication type:
- journal article
Oophorectomy promotes islet amyloid formation in human islet amyloid polypeptide transgenic mice.
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- 2001
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- Publication type:
- journal article
The constitutive secretory pathway is a major route for islet amyloid polypeptide secretion in neonatal but not adult rat islet cells.
- Published in:
- 2000
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- Publication type:
- journal article
Insulinotropic Effects of Neprilysin and/or Angiotensin Receptor Inhibition in Mice.
- Published in:
- Frontiers in Endocrinology, 2022, v. 13, p. 1, doi. 10.3389/fendo.2022.888867
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- Publication type:
- Article
Cystic Fibrosis–Related Diabetes Workshop: Research Priorities Spanning Disease Pathophysiology, Diagnosis, and Outcomes.
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- Diabetes Care, 2023, v. 46, n. 6, p. 1112, doi. 10.2337/dc23-0380
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- Publication type:
- Article
Probing the Meaning of Persistent Propeptide Release in Type 1 Diabetes.
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- 2019
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- Publication type:
- journal article
Islet Interleukin-1β Immunoreactivity Is an Early Feature of Cystic Fibrosis That May Contribute to β-Cell Failure.
- Published in:
- Diabetes Care, 2018, v. 41, n. 4, p. 823, doi. 10.2337/dc17-1387
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- Publication type:
- Article
Islet Interleukin-1β Immunoreactivity Is an Early Feature of Cystic Fibrosis That May Contribute to β-Cell Failure.
- Published in:
- 2018
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- Publication type:
- journal article
Neprilysin Deficiency Is Associated With Expansion of Islet β-Cell Mass in High Fat-Fed Mice.
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- Journal of Histochemistry & Cytochemistry, 2018, v. 66, n. 7, p. 523, doi. 10.1369/0022155418765164
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- Publication type:
- Article
Erratum. Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings. Diabetes 2023;72:433–448.
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- 2023
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- Publication type:
- Correction Notice
Cystic Fibrosis–Related Diabetes Workshop: Research Priorities Spanning Disease Pathophysiology, Diagnosis, and Outcomes.
- Published in:
- Diabetes, 2023, v. 72, n. 6, p. 677, doi. 10.2337/db22-0949
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- Publication type:
- Article
Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings.
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- Diabetes, 2023, v. 72, n. 4, p. 433, doi. 10.2337/db22-0942
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- Publication type:
- Article
130-OR: Statin Exposure Increases Star (Steroidogenic Acute Regulatory Protein) Expression in Islets: A Novel Mechanism for ß-Cell Dysfunction and Increased Diabetes Risk?
- Published in:
- Diabetes, 2021, v. 70, p. N.PAG, doi. 10.2337/db21-130-OR
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- Publication type:
- Article
1238-P: The Proinflammatory but Not Cytotoxic Effect of Aggregated IAPP on Islet Endothelial Cells Requires TLR2/4 Signaling.
- Published in:
- Diabetes, 2021, v. 70, p. N.PAG, doi. 10.2337/db21-1238-P
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- Publication type:
- Article
1797-P: Effect of LCZ696 and Its Components Sacubitril and Valsartan on Insulin Secretion and Glucose Homeostasis in Mice.
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- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-1797-P
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- Publication type:
- Article
2043-P: Hyaluronan Produced by Inflamed Islet Endothelial Cells Contributes to HIAPP Aggregation.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-2043-P
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- Publication type:
- Article
2042-P: Loss of Apoptosis Repressor with Caspase Recruitment Domain Promotes High-Fat Diet Induced Hyperglycemia In Vivo.
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- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-2042-P
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- Publication type:
- Article
2040-P: Chronic Activation of CREB by Islet Amyloid Increases Star (Steroidogenic Acute Regulatory Protein) Expression in Islets.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-2040-P
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- Publication type:
- Article
2039-P: Plasmin-Mediated Cleavage of Human Islet Amyloid Polypeptide (hIAPP) Protects ß-Cells from Amyloid-Induced Toxicity.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-2039-P
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- Publication type:
- Article
2132-P: Islet Amyloid Deposition Is Cytotoxic to Islet Endothelial Cells.
- Published in:
- Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-2132-P
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- Publication type:
- Article
2126-P: Physiological Concentrations of IL-1 Beta Promote Islet Amyloid Deposition by Increasing Beta-Cell Secretion of Human Islet Amyloid Polypeptide.
- Published in:
- Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-2126-P
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- Publication type:
- Article
2125-P: Increased StAR (Steroidogenic Acute Regulatory Protein) Is Detrimental to ß Cells and Promotes Mitochondrial Dysfunction.
- Published in:
- Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-2125-P
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- Publication type:
- Article