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Islet amyloid polypeptide aggregation exerts cytotoxic and proinflammatory effects on the islet vasculature in mice.
- Published in:
- Diabetologia, 2022, v. 65, n. 10, p. 1687, doi. 10.1007/s00125-022-05756-9
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- Publication type:
- Article
Low concentration IL-1β promotes islet amyloid formation by increasing hIAPP release from humanised mouse islets in vitro.
- Published in:
- Diabetologia, 2020, v. 63, n. 11, p. 2385, doi. 10.1007/s00125-020-05232-2
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- Publication type:
- Article
A tale of two pancreases: exocrine pathology and endocrine dysfunction.
- Published in:
- Diabetologia, 2020, v. 63, n. 10, p. 2030, doi. 10.1007/s00125-020-05210-8
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- Publication type:
- Article
Use of the PET ligand florbetapir for in vivo imaging of pancreatic islet amyloid deposits in hIAPP transgenic mice.
- Published in:
- Diabetologia, 2018, v. 61, n. 10, p. 2215, doi. 10.1007/s00125-018-4695-y
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- Publication type:
- Article
The islet endothelial cell: a novel contributor to beta cell secretory dysfunction in diabetes.
- Published in:
- Diabetologia, 2017, v. 60, n. 6, p. 952, doi. 10.1007/s00125-017-4272-9
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- Publication type:
- Article
The S20G substitution in hIAPP is more amyloidogenic and cytotoxic than wild-type hIAPP in mouse islets.
- Published in:
- Diabetologia, 2016, v. 59, n. 10, p. 2166, doi. 10.1007/s00125-016-4045-x
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- Publication type:
- Article
Loss of perlecan heparan sulfate glycosaminoglycans lowers body weight and decreases islet amyloid deposition in human islet amyloid polypeptide transgenic mice.
- Published in:
- PEDS: Protein Engineering, Design & Selection, 2019, v. 32, n. 2, p. 95, doi. 10.1093/protein/gzz041
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- Publication type:
- Article
Impact of intra-abdominal fat and age on insulin sensitivity and beta-cell function.
- Published in:
- 2004
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- Publication type:
- journal article
Intra-abdominal fat is a major determinant of the National Cholesterol Education Program Adult Treatment Panel III criteria for the metabolic syndrome.
- Published in:
- 2004
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- Publication type:
- journal article
Increased dietary fat promotes islet amyloid formation and beta-cell secretory dysfunction in a transgenic mouse model of islet amyloid.
- Published in:
- 2003
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- Publication type:
- journal article
Beta-cell function is a major contributor to oral glucose tolerance in high-risk relatives of four ethnic groups in the U.S.
- Published in:
- 2002
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- Publication type:
- journal article
β-Cell Function Is a Major Contributor to Oral Glucose Tolerance in High-Risk Relatives of Four Ethnic Groups in the U.S.
- Published in:
- Diabetes, 2002, v. 51, n. 7, p. 2170
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- Publication type:
- Article
The concurrent accumulation of intra-abdominal and subcutaneous fat explains the association between insulin resistance and plasma leptin concentrations : distinct metabolic effects of two fat compartments.
- Published in:
- 2002
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- Publication type:
- journal article
Islet amyloid develops diffusely throughout the pancreas before becoming severe and replacing endocrine cells.
- Published in:
- 2001
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- Publication type:
- journal article
Oophorectomy promotes islet amyloid formation in human islet amyloid polypeptide transgenic mice.
- Published in:
- 2001
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- Publication type:
- journal article
The constitutive secretory pathway is a major route for islet amyloid polypeptide secretion in neonatal but not adult rat islet cells.
- Published in:
- 2000
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- Publication type:
- journal article
Mechanisms linking obesity to insulin resistance and type 2 diabetes.
- Published in:
- Nature, 2006, v. 444, n. 7121, p. 840, doi. 10.1038/nature05482
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- Publication type:
- Article
Pancreas and islet morphology in cystic fibrosis: clues to the etiology of cystic fibrosis-related diabetes.
- Published in:
- Frontiers in Endocrinology, 2023, p. 01, doi. 10.3389/fendo.2023.1269139
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- Publication type:
- Article
Erratum. Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings. Diabetes 2023;72:433–448.
- Published in:
- 2023
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- Publication type:
- Correction Notice
Cystic Fibrosis–Related Diabetes Workshop: Research Priorities Spanning Disease Pathophysiology, Diagnosis, and Outcomes.
- Published in:
- Diabetes, 2023, v. 72, n. 6, p. 677, doi. 10.2337/db22-0949
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- Publication type:
- Article
Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases: Workshop Proceedings.
- Published in:
- Diabetes, 2023, v. 72, n. 4, p. 433, doi. 10.2337/db22-0942
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- Publication type:
- Article
130-OR: Statin Exposure Increases Star (Steroidogenic Acute Regulatory Protein) Expression in Islets: A Novel Mechanism for ß-Cell Dysfunction and Increased Diabetes Risk?
- Published in:
- Diabetes, 2021, v. 70, p. N.PAG, doi. 10.2337/db21-130-OR
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- Publication type:
- Article
1238-P: The Proinflammatory but Not Cytotoxic Effect of Aggregated IAPP on Islet Endothelial Cells Requires TLR2/4 Signaling.
- Published in:
- Diabetes, 2021, v. 70, p. N.PAG, doi. 10.2337/db21-1238-P
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- Publication type:
- Article
1797-P: Effect of LCZ696 and Its Components Sacubitril and Valsartan on Insulin Secretion and Glucose Homeostasis in Mice.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-1797-P
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- Publication type:
- Article
2043-P: Hyaluronan Produced by Inflamed Islet Endothelial Cells Contributes to HIAPP Aggregation.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-2043-P
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- Publication type:
- Article
2042-P: Loss of Apoptosis Repressor with Caspase Recruitment Domain Promotes High-Fat Diet Induced Hyperglycemia In Vivo.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-2042-P
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- Publication type:
- Article
2040-P: Chronic Activation of CREB by Islet Amyloid Increases Star (Steroidogenic Acute Regulatory Protein) Expression in Islets.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-2040-P
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- Publication type:
- Article
2039-P: Plasmin-Mediated Cleavage of Human Islet Amyloid Polypeptide (hIAPP) Protects ß-Cells from Amyloid-Induced Toxicity.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-2039-P
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- Publication type:
- Article
2132-P: Islet Amyloid Deposition Is Cytotoxic to Islet Endothelial Cells.
- Published in:
- Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-2132-P
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- Publication type:
- Article
2125-P: Increased StAR (Steroidogenic Acute Regulatory Protein) Is Detrimental to ß Cells and Promotes Mitochondrial Dysfunction.
- Published in:
- Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-2125-P
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- Publication type:
- Article
2126-P: Physiological Concentrations of IL-1 Beta Promote Islet Amyloid Deposition by Increasing Beta-Cell Secretion of Human Islet Amyloid Polypeptide.
- Published in:
- Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-2126-P
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- Publication type:
- Article
2124-P: The Tissue Plasminogen Activator (tPA)/Plasmin System Reduces Amyloid Formation by Cleaving Human Islet Amyloid Polypeptide (hIAPP).
- Published in:
- Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-2124-P
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- Publication type:
- Article
Apoptosis Repressor With Caspase Recruitment Domain Ameliorates Amyloid-Induced β-Cell Apoptosis and JNK Pathway Activation.
- Published in:
- 2017
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- Publication type:
- journal article
Human Type 1 Diabetes Is Characterized by an Early, Marked, Sustained, and Islet-Selective Loss of Sympathetic Nerves.
- Published in:
- 2016
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- Publication type:
- journal article
Amyloid Formation in Isolated Islets Is Not Associated with Endoplasmic Reticulum (ER) Stress.
- Published in:
- Diabetes, 2007, v. 56, p. A435
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- Publication type:
- Article
Amyloid-Induced Oxidative Stress Contributes to Reduced Islet Cell Viability But Does Not Impact Insulin Secretion.
- Published in:
- Diabetes, 2007, v. 56, p. A436
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- Publication type:
- Article
Inhibition of the Amyloid-Degrading Enzyme, Neprilysin, Results in Increased Amyloid in Islets from Human Islet Amyloid Polypeptide (hIAPP) Transgenic Mice.
- Published in:
- Diabetes, 2007, v. 56, p. A436
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- Publication type:
- Article
Identification of the Amyloid-Degrading Enzyme Neprilysin in Mouse Islets and Potential Role in Islet Amyloidogenesis.
- Published in:
- Diabetes, 2007, v. 56, n. 2, p. 304, doi. 10.2337/db06-0430
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- Publication type:
- Article
Long-Term Treatment With Rosiglitazone and Metformin Reduces the Extent of, but Does Not Prevent, Islet Amyloid Deposition in Mice Expressing the Gene for Human Islet Amyloid Polypeptide.
- Published in:
- Diabetes, 2005, v. 54, n. 7, p. 2235, doi. 10.2337/diabetes.54.7.2235
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- Publication type:
- Article
A reduced-fat diet and aerobic exercise in Japanese Americans with impaired glucose tolerance decreases intra-abdominal fat and improves insulin sensitivity but not beta-cell function.
- Published in:
- 2005
- By:
- Publication type:
- journal article
A Reduced-Fat Diet and Aerobic Exercise in Japanese Americans With Impaired Glucose Tolerance Decreases Intra-Abdominal Fat and Improves Insulin Sensitivity but not β-Cell Function.
- Published in:
- Diabetes, 2005, v. 54, n. 2, p. 340, doi. 10.2337/diabetes.54.2.340
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- Publication type:
- Article
The Impact of Hypoxia on the Host-Pathogen Interaction between Neutrophils and Staphylococcus aureus.
- Published in:
- International Journal of Molecular Sciences, 2019, v. 20, n. 22, p. 5561, doi. 10.3390/ijms20225561
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- Publication type:
- Article
Finding Marx in the Occupy Wall Street Movement.
- Published in:
- 2019
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- Publication type:
- Book Review
Searching for Marx in the Occupy Wall Street Movement.
- Published in:
- 2019
- By:
- Publication type:
- Book Review
Insulinotropic Effects of Neprilysin and/or Angiotensin Receptor Inhibition in Mice.
- Published in:
- Frontiers in Endocrinology, 2022, v. 13, p. 1, doi. 10.3389/fendo.2022.888867
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- Publication type:
- Article
Breaking the cycle through better school siting: a collaborative project to facilitate the effective use of EPA's guidelines with Georgia's educational leaders.
- Published in:
- International Journal on Disability & Human Development (De Gruyter), 2013, v. 12, n. 4, p. 473, doi. 10.1515/ijdhd-2013-0210
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- Publication type:
- Article
Islet Amyloid: A Critical Entity in the Pathogenesis of Type 2 Diabetes.
- Published in:
- Journal of Clinical Endocrinology & Metabolism, 2004, v. 89, n. 8, p. 3629, doi. 10.1210/jc.2004-0405
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- Publication type:
- Article
Islet amyloid formation is an important determinant for inducing islet inflammation in high-fat-fed human IAPP transgenic mice.
- Published in:
- Diabetologia, 2014, v. 57, n. 9, p. 1884, doi. 10.1007/s00125-014-3304-y
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- Publication type:
- Article
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes.
- Published in:
- Nature Immunology, 2010, v. 11, n. 10, p. 897, doi. 10.1038/ni.1935
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- Publication type:
- Article
The Role of Hyaluronan and the Extracellular Matrix in Islet Inflammation and Immune Regulation.
- Published in:
- Current Diabetes Reports, 2012, v. 12, n. 5, p. 471, doi. 10.1007/s11892-012-0297-0
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- Publication type:
- Article