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Structure‐based non‐nucleoside inhibitor design: Developing inhibitors that are effective against resistant mutants.
- Published in:
- Chemical Biology & Drug Design, 2021, v. 97, n. 1, p. 4, doi. 10.1111/cbdd.13766
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- Publication type:
- Article
Discovery of Novel Inhibitors of HIV-1 Reverse Transcriptase Through Virtual Screening of Experimental and Theoretical Ensembles.
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- Chemical Biology & Drug Design, 2014, v. 83, n. 5, p. 521, doi. 10.1111/cbdd.12277
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- Publication type:
- Article
Bicyclic Hydroxy-1 H-pyrrolopyridine-trione Containing HIV-1 Integrase Inhibitors.
- Published in:
- Chemical Biology & Drug Design, 2012, v. 79, n. 2, p. 157, doi. 10.1111/j.1747-0285.2011.01270.x
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- Publication type:
- Article
Structures of HIV-1 reverse transcriptase with pre- and post-translocation AZTMP-terminated DNA.
- Published in:
- EMBO Journal, 2002, v. 21, n. 23, p. 6614, doi. 10.1093/emboj/cdf637
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- Publication type:
- Article
Crystal structure of HIV-1 reverse transcriptase in complex with a polypurine tract RNA:DNA.
- Published in:
- EMBO Journal, 2001, v. 20, n. 6, p. 1449, doi. 10.1093/emboj/20.6.1449
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- Publication type:
- Article
Correction to: An analytical pipeline for identifying and mapping the integration sites of HIV and other retroviruses.
- Published in:
- 2020
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- Publication type:
- Correction Notice
An analytical pipeline for identifying and mapping the integration sites of HIV and other retroviruses.
- Published in:
- BMC Genomics, 2020, v. 21, n. 1, p. 1, doi. 10.1186/s12864-020-6647-4
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- Publication type:
- Article
Selectivity for strand-transfer over 3-processing and susceptibility to clinical resistance of HIV-1 integrase inhibitors are driven by key enzyme-DNA interactions in the active site.
- Published in:
- Nucleic Acids Research, 2016, v. 44, n. 14, p. 6896, doi. 10.1093/nar/gkw592
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- Publication type:
- Article
HRP2 determines the efficiency and specificity of HIV-1 integration in LEDGF/p75 knockout cells but does not contribute to the antiviral activity of a potent LEDGF/p75-binding site integrase inhibitor.
- Published in:
- Nucleic Acids Research, 2012, v. 40, n. 22, p. 11518, doi. 10.1093/nar/gks913
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- Publication type:
- Article
Crystal engineering of HIV-1 reverse transcriptase for structure-based drug design.
- Published in:
- Nucleic Acids Research, 2008, v. 36, n. 15, p. 5083, doi. 10.1093/nar/gkn464
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- Publication type:
- Article
Publisher Correction: Structural basis for the inhibition of HTLV-1 integration inferred from cryo-EM deltaretroviral intasome structures.
- Published in:
- 2021
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- Publication type:
- Correction Notice
Structural basis for the inhibition of HTLV-1 integration inferred from cryo-EM deltaretroviral intasome structures.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25284-1
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- Publication type:
- Article
Human Immunodeficiency Virus Reverse Transcriptase T Helper Epitopes Identified in Mice and Humans: Correlation with a Cytotoxic T Cell Epitope.
- Published in:
- Journal of Infectious Diseases, 1991, v. 164, n. 6, p. 1058
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- Publication type:
- Article
Structural basis of HIV-1 resistance to AZT by excision.
- Published in:
- Nature Structural & Molecular Biology, 2010, v. 17, n. 10, p. 1202, doi. 10.1038/nsmb.1908
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- Publication type:
- Article
Structures of HIV-1 RT-DNA complexes before and after incorporation of the anti-AIDS drug tenofovir.
- Published in:
- Nature Structural & Molecular Biology, 2004, v. 11, n. 5, p. 469, doi. 10.1038/nsmb760
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- Publication type:
- Article
Selective expression of a ski transgene affects IIb fast muscles and skeletal structure.
- Published in:
- Developmental Dynamics, 1996, v. 205, n. 1, p. 13, doi. 10.1002/(SICI)1097-0177(199601)205:1<13::AID-AJA2>3.0.CO;2-8
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- Publication type:
- Article
A Mouse Strain Defective in Both T Cells and NK Cells Has Enhanced Sensitivity to Tumor Induction by Plasmid DNA Expressing Both Activated H-Ras and c-Myc.
- Published in:
- PLoS ONE, 2014, v. 9, n. 10, p. 1, doi. 10.1371/journal.pone.0108926
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- Publication type:
- Article
Mouse papillomavirus type 1 (MmuPV1) DNA is frequently integrated in benign tumors by microhomology-mediated end-joining.
- Published in:
- PLoS Pathogens, 2021, v. 17, n. 8, p. 1, doi. 10.1371/journal.ppat.1009812
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- Publication type:
- Article
Integration in oncogenes plays only a minor role in determining the in vivo distribution of HIV integration sites before or during suppressive antiretroviral therapy.
- Published in:
- PLoS Pathogens, 2021, v. 17, n. 4, p. 1, doi. 10.1371/journal.ppat.1009141
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- Publication type:
- Article
A human oncogene formed by the fusion of truncated tropomyosin and protein tyrosine kinase sequences.
- Published in:
- Nature, 1986, v. 319, n. 6056, p. 743, doi. 10.1038/319743a0
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- Publication type:
- Article
Clonal expansion of SIV-infected cells in macaques on antiretroviral therapy is similar to that of HIV-infected cells in humans.
- Published in:
- PLoS Pathogens, 2019, v. 15, n. 7, p. 1, doi. 10.1371/journal.ppat.1007869
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- Publication type:
- Article
THE ORIGIN AND STRUCTURE OF ENDOGENOUS RETROVIRAL DNA.
- Published in:
- Annals of the New York Academy of Sciences, 1980, v. 354, n. 1, p. 379, doi. 10.1111/j.1749-6632.1980.tb27979.x
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- Publication type:
- Article
A Practical Approach to Bicyclic Carbamoyl Pyridones with Application to the Synthesis of HIV-1 Integrase Strand Transfer Inhibitors.
- Published in:
- Molecules, 2023, v. 28, n. 3, p. 1428, doi. 10.3390/molecules28031428
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- Publication type:
- Article
False-Positive HIV PCR Test Following Ex Vivo Lentiviral Gene Transfer Treatment of X-linked Severe Combined Immunodeficiency Vector.
- Published in:
- Molecular Therapy, 2014, v. 22, n. 2, p. 244, doi. 10.1038/mt.2013.296
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- Publication type:
- Article
Overexpression of p21<sup>waf1/cip1</sup> arrests the growth of chicken embryo fibroblasts that overexpress E2F1.
- Published in:
- Oncogene, 1998, v. 16, n. 24, p. 3115, doi. 10.1038/sj.onc.1201849
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- Publication type:
- Article
PCR amplification of DNA containing non‐standard base pairs by variants of reverse transcriptase from Human Immunodeficiency Virus‐1.
- Published in:
- Nucleic Acids Research, 2004, v. 32, n. 2, p. 728, doi. 10.1093/nar/gkh241
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- Publication type:
- Article
Efficacies of Cabotegravir and Bictegravir against drug-resistant HIV-1 integrase mutants.
- Published in:
- Retrovirology, 2018, v. 15, n. 1, p. N.PAG, doi. 10.1186/s12977-018-0420-7
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- Publication type:
- Article
The Integrator complex controls the termination of transcription at diverse classes of gene targets.
- Published in:
- Cell Research, 2015, v. 25, n. 3, p. 288, doi. 10.1038/cr.2015.19
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- Publication type:
- Article
Why Do HIV-1 and HIV-2 Use Different Pathways to Develop AZT Resistance?
- Published in:
- PLoS Pathogens, 2006, v. 2, n. 2, p. 0101, doi. 10.1371/journal.ppat.0020010
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- Publication type:
- Article
HIV-1 viremia not suppressible by antiretroviral therapy can originate from large T cell clones producing infectious virus.
- Published in:
- 2020
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- Publication type:
- journal article
HIV-1 in lymph nodes is maintained by cellular proliferation during antiretroviral therapy.
- Published in:
- 2019
- By:
- Publication type:
- journal article
LINE1-Mediated Reverse Transcription and Genomic Integration of SARS-CoV-2 mRNA Detected in Virus-Infected but Not in Viral mRNA-Transfected Cells.
- Published in:
- Viruses (1999-4915), 2023, v. 15, n. 3, p. 629, doi. 10.3390/v15030629
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- Publication type:
- Article
INSTIs and NNRTIs Potently Inhibit HIV-1 Polypurine Tract Mutants in a Single Round Infection Assay.
- Published in:
- Viruses (1999-4915), 2021, v. 13, n. 12, p. 2501, doi. 10.3390/v13122501
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- Publication type:
- Article
Clonal Expansion of Infected CD4+ T Cells in People Living with HIV.
- Published in:
- Viruses (1999-4915), 2021, v. 13, n. 10, p. 2078, doi. 10.3390/v13102078
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- Publication type:
- Article
Crystal Structure of a Retroviral Polyprotein: Prototype Foamy Virus Protease-Reverse Transcriptase (PR-RT).
- Published in:
- Viruses (1999-4915), 2021, v. 13, n. 8, p. 1495, doi. 10.3390/v13081495
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- Publication type:
- Article
Tracking HIV-1-Infected Cell Clones Using Integration Site-Specific qPCR.
- Published in:
- Viruses (1999-4915), 2021, v. 13, n. 7, p. 1235, doi. 10.3390/v13071235
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- Publication type:
- Article
Integrase Strand Transfer Inhibitors Are Effective Anti-HIV Drugs.
- Published in:
- Viruses (1999-4915), 2021, v. 13, n. 2, p. 205, doi. 10.3390/v13020205
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- Publication type:
- Article
Dynamic Shifts in the HIV Proviral Landscape During Long Term Combination Antiretroviral Therapy: Implications for Persistence and Control of HIV Infections.
- Published in:
- Viruses (1999-4915), 2020, v. 12, n. 2, p. 136, doi. 10.3390/v12020136
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- Publication type:
- Article
Structures of Wild-Type and AZT-Resistant HIV-1 Reverse Transcriptase Complexed with AZTppppA Yield Insights into the Nucleotide Excision Mechanism.
- Published in:
- FASEB Journal, 2007, v. 21, n. 5, p. A640
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- Publication type:
- Article
On the detection of multiple-binding modes of ligands to proteins, from biological, structural, and modeling data.
- Published in:
- Journal of Computer-Aided Molecular Design, 2003, v. 17, n. 2-4, p. 129, doi. 10.1023/A:1025313705564
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- Publication type:
- Article
DNA methylation and oncogene expression in methapyrilene-induced rat liver tumors and in treated hepatocytes in culture.
- Published in:
- Molecular Carcinogenesis, 1991, v. 4, n. 3, p. 203, doi. 10.1002/mc.2940040307
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- Publication type:
- Article
Proviruses with identical sequences comprise a large fraction of the replication-competent HIV reservoir.
- Published in:
- PLoS Pathogens, 2017, v. 13, n. 3, p. 1, doi. 10.1371/journal.ppat.1006283
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- Publication type:
- Article
Reduced Genotoxicity of Avian Sarcoma Leukosis Virus Vectors in Rhesus Long-term Repopulating Cells Compared to Standard Murine Retrovirus Vectors.
- Published in:
- Molecular Therapy, 2008, v. 16, n. 9, p. 1617, doi. 10.1038/mt.2008.135
- By:
- Publication type:
- Article
Corrigendum to “Reduced Genotoxicity of Avian Sarcoma Leukosis Virus Vectors in Rhesus Long-term Repopulating Cells Compared to Standard Murine Retrovirus Vectors”.
- Published in:
- 2008
- By:
- Publication type:
- Correction Notice
732. Avian Sarcoma Leukosis Virus Vectors Can Transduce Rhesus Macaque HSCs and Result in a Potentially Safer Integration Profile.
- Published in:
- Molecular Therapy, 2006, v. 13, p. S283, doi. 10.1016/j.ymthe.2006.08.813
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- Publication type:
- Article
North- and South-Bicyclo[3.1.0]Hexene Nucleosides: The Effect of Ring Planarity on Anti-HIV Activity.
- Published in:
- ChemMedChem, 2009, v. 4, n. 8, p. 1354, doi. 10.1002/cmdc.200900153
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- Publication type:
- Article
Inside Cover: North- and South-Bicyclo[3.1.0]Hexene Nucleosides: The Effect of Ring Planarity on Anti-HIV Activity (ChemMedChem 8/2009).
- Published in:
- ChemMedChem, 2009, v. 4, n. 8, p. 1210, doi. 10.1002/cmdc.200990036
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- Publication type:
- Article
D-(+)- iso-Methanocarbathymidine: a High-Affinity Substrate for Herpes Simplex Virus 1 Thymidine Kinase.
- Published in:
- ChemMedChem, 2008, v. 3, n. 7, p. 1129, doi. 10.1002/cmdc.200800027
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- Publication type:
- Article
Identification of a 3-aminoimidazo[1,2-a]pyridine inhibitor of HIV-1 reverse transcriptase.
- Published in:
- Virology Journal, 2012, v. 9, n. 1, p. 305, doi. 10.1186/1743-422X-9-305
- By:
- Publication type:
- Article
HIV Infected T Cells Can Proliferate in vivo Without Inducing Expression of the Integrated Provirus.
- Published in:
- Frontiers in Microbiology, 2019, p. 1, doi. 10.3389/fmicb.2019.02204
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- Publication type:
- Article