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Altered intercellular communication and extracellular matrix signaling as a potential disease mechanism in human hypertrophic cardiomyopathy.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-08561-x
By:
- Larson, Amy;
- Codden, Christina J.;
- Huggins, Gordon S.;
- Rastegar, Hassan;
- Chen, Frederick Y.;
- Maron, Barry J.;
- Rowin, Ethan J.;
- Maron, Martin S.;
- Chin, Michael T.
Publication type:
Article
Plasma Proteomic Profiling in Hypertrophic Cardiomyopathy Patients before and after Surgical Myectomy Reveals Post-Procedural Reduction in Systemic Inflammation.
Published in:
International Journal of Molecular Sciences, 2021, v. 22, n. 5, p. 2474, doi. 10.3390/ijms22052474
By:
- Larson, Amy;
- Libermann, Towia A.;
- Bowditch, Heather;
- Das, Gaurav;
- Diakos, Nikolaos;
- Huggins, Gordon S.;
- Rastegar, Hassan;
- Chen, Frederick Y.;
- Rowin, Ethan J.;
- Maron, Martin S.;
- Chin, Michael T.;
- Lee, Cheolju
Publication type:
Article
Deletion of GSK-3beta in mice leads to hypertrophic cardiomyopathy secondary to cardiomyoblast hyperproliferation.
Published in:
2008
By:
- Kerkela, Risto;
- Kockeritz, Lisa;
- MacAulay, Katrina;
- Jibin Zhou;
- Doble, Bradley W.;
- Beahm, Cara;
- Greytak, Sarah;
- Woulfe, Kathleen;
- Trivedi, Chinmay M.;
- Woodgett, James R.;
- Epstein, Jonathan A.;
- Force, Thomas;
- Huggins, Gordon S.;
- Zhou, Jibin
Publication type:
journal article
Specialized Pro-Resolving Mediators Reduce Scarring After Cleft Lip Repair.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.871200
By:
- Papathanasiou, Evangelos;
- Scott, Andrew R.;
- Trotman, Carroll Ann;
- Beale, Corinna;
- Price, Lori Lyn;
- Huggins, Gordon S.;
- Zhang, Yang;
- Georgakoudi, Irene;
- Van Dyke, Thomas E.
Publication type:
Article
A syndrome of tricuspid atresia in mice with a targeted mutation of the gene encoding Fog-2.
Published in:
Nature Genetics, 2000, v. 25, n. 3, p. 353, doi. 10.1038/77146
By:
- Svensson, Eric C.;
- Huggins, Gordon S.;
- Lin, Hua;
- Clendenin, Cynthia;
- Jiang, Fang;
- Tufts, Rachel;
- Dardik, Fred B.;
- Leiden, Jeffrey M.
Publication type:
Article
Diagnostic accuracy of point-of-care ultrasound with artificial intelligence-assisted assessment of left ventricular ejection fraction.
Published in:
NPJ Digital Medicine, 2023, v. 6, n. 1, p. 1, doi. 10.1038/s41746-023-00945-1
By:
- Motazedian, Pouya;
- Marbach, Jeffrey A.;
- Prosperi-Porta, Graeme;
- Parlow, Simon;
- Di Santo, Pietro;
- Abdel-Razek, Omar;
- Jung, Richard;
- Bradford, William B.;
- Tsang, Miranda;
- Hyon, Michael;
- Pacifici, Stefano;
- Mohanty, Sharanya;
- Ramirez, F. Daniel;
- Huggins, Gordon S.;
- Simard, Trevor;
- Hon, Stephanie;
- Hibbert, Benjamin
Publication type:
Article
Notch Pathway Activation Contributes to Inhibition of C2C12 Myoblast Differentiation by Ethanol.
Published in:
PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0071632
By:
- Arya, Michelle A.;
- Tai, Albert K.;
- Wooten, Eric C.;
- Parkin, Christopher D.;
- Kudryavtseva, Elena;
- Huggins, Gordon S.
Publication type:
Article
Application of Gene Network Analysis Techniques Identifies AXIN1/PDIA2 and Endoglin Haplotypes Associated with Bicuspid Aortic Valve.
Published in:
PLoS ONE, 2010, v. 5, n. 1, p. 1, doi. 10.1371/journal.pone.0008830
By:
- Wooten, Eric C.;
- Iyer, Lakshmanan K.;
- ClaudiaMontefusco, Maria;
- Hedgepeth, Alyson Kelley;
- Payne, Douglas D.;
- Kapur, Navin K.;
- Housman, David E.;
- Mendelsohn, Michael E.;
- Huggins, Gordon S.
Publication type:
Article
Transcriptome analysis of pig intestinal cell monolayers infected with <italic>Cryptosporidium parvum</italic> asexual stages.
Published in:
Parasites & Vectors, 2018, v. 11, p. 1, doi. 10.1186/s13071-018-2754-3
By:
- Mirhashemi, Marzieh Ezzaty;
- Noubary, Farzad;
- Chapman-Bonofiglio, Susan;
- Tzipori, Saul;
- Huggins, Gordon S.;
- Widmer, Giovanni
Publication type:
Article
Variation in estrogen-related genes associated with cardiovascular phenotypes and circulating estradiol, testosterone, and dehydroepiandrosterone sulfate levels.
Published in:
2008
By:
- Peter, Inga;
- Kelley-Hedgepeth, Alyson;
- Fox, Caroline S;
- Cupples, L Adrienne;
- Huggins, Gordon S;
- Housman, David E;
- Karas, Richard H;
- Mendelsohn, Michael E;
- Levy, Daniel;
- Murabito, Joanne M
Publication type:
journal article
Augmentation index and aortic stiffness in bicuspid aortic valve patients with non-dilated proximal aortas.
Published in:
BMC Cardiovascular Disorders, 2013, v. 13, n. 1, p. 1, doi. 10.1186/1471-2261-13-19
By:
- Warner, Patrick J.;
- Al-Quthami, Adeeb;
- Brooks, Erica L.;
- Kelley-Hedgepeth, Alyson;
- Patvardhan, Eshan;
- Kuvin, Jeffrey T.;
- Heffernan, Kevin S.;
- Huggins, Gordon S.
Publication type:
Article
Augmentation index and aortic stiffness in bicuspid aortic valve patients with non-dilated proximal aortas.
Published in:
2013
By:
- Warner, Patrick J;
- Al-Quthami, Adeeb;
- Brooks, Erica L;
- Kelley-Hedgepeth, Alyson;
- Patvardhan, Eshan;
- Kuvin, Jeffrey T;
- Heffernan, Kevin S;
- Huggins, Gordon S
Publication type:
journal article
Daxx inhibits muscle differentiation by repressing E2A-mediated transcription.
Published in:
Journal of Cellular Biochemistry, 2009, v. 107, n. 3, p. 438, doi. 10.1002/jcb.22140
By:
- Gupta, Amitabh;
- Hou, Rong;
- Liu, Liming;
- Hiroyasu, Shungo;
- Hadix, Jennifer A.;
- Huggins, Gordon S.;
- Sibinga, Nicholas E.S.
Publication type:
Article
Serum adiponectin levels in patients with acute coronary syndromes: Serial changes and relation to infarct size.
Published in:
Diabetes & Vascular Disease Research, 2015, v. 12, n. 6, p. 411, doi. 10.1177/1479164115592638
By:
- Alkofide, Hadeel;
- Huggins, Gordon S.;
- Ruthazer, Robin;
- Beshansky, Joni R.;
- Selker, Harry P.
Publication type:
Article
Biogeographic Ancestry, Self-Identified Race, and Admixture-Phenotype Associations in the Heart SCORE Study.
Published in:
American Journal of Epidemiology, 2012, v. 176, n. 2, p. 146, doi. 10.1093/aje/kwr518
By:
- Halder, Indrani;
- Kip, Kevin E.;
- Mulukutla, Suresh R.;
- Aiyer, Aryan N.;
- Marroquin, Oscar C.;
- Huggins, Gordon S.;
- Reis, Steven E.
Publication type:
Article
Cover Image.
Published in:
FASEB Journal, 2024, v. 38, n. 3, p. 1, doi. 10.1096/fsb2.23545
By:
- Bestepe, Furkan;
- Ghanem, George F.;
- Fritsche, Colette M.;
- Weston, James;
- Sahay, Sumedha;
- Mauro, Amanda K.;
- Sahu, Parul;
- Tas, Sude M.;
- Ruemmele, Brooke;
- Persing, Sarah;
- Good, Miranda E.;
- Chatterjee, Abhishek;
- Huggins, Gordon S.;
- Salehi, Payam;
- Icli, Basak
Publication type:
Article
MicroRNA‐409‐3p/BTG2 signaling axis improves impaired angiogenesis and wound healing in obese mice.
Published in:
FASEB Journal, 2024, v. 38, n. 3, p. 1, doi. 10.1096/fj.202302124RR
By:
- Bestepe, Furkan;
- Ghanem, George F.;
- Fritsche, Colette M.;
- Weston, James;
- Sahay, Sumedha;
- Mauro, Amanda K.;
- Sahu, Parul;
- Tas, Sude M.;
- Ruemmele, Brooke;
- Persing, Sarah;
- Good, Miranda E.;
- Chatterjee, Abhishek;
- Huggins, Gordon S.;
- Salehi, Payam;
- Icli, Basak
Publication type:
Article
Little ROCK is a ROCK1 pseudogene expressed in human smooth muscle cells.
Published in:
BMC Genetics, 2010, v. 11, p. 22, doi. 10.1186/1471-2156-11-22
By:
- Montefusco, Maria Claudia;
- Merlo, Kristen;
- Bryan, Crystal D.;
- Surks, Howard K.;
- Reis, Steven E.;
- Mendelsohn, Michael E.;
- Huggins, Gordon S.
Publication type:
Article
Serial Biomarkers of De Novo Lipogenesis Fatty Acids and Incident Heart Failure in Older Adults: The Cardiovascular Health Study.
Published in:
2020
By:
- Yujin Lee;
- Lai, Heidi T. M.;
- de Oliveira Otto, Marcia C.;
- Lemaitre, Rozenn N.;
- McKnight, Barbara;
- King, Irena B.;
- Xiaoling Song;
- Huggins, Gordon S.;
- Vest, Amanda R.;
- Siscovick, David S.;
- Mozaffarian, Dariush;
- Lee, Yujin;
- Song, Xiaoling
Publication type:
journal article
Change in Cardiometabolic Risk Factors Associated With Magnitude of Weight Regain 3 Years After a 1-Year Intensive Lifestyle Intervention in Type 2 Diabetes Mellitus: The Look AHEAD Trial.
Published in:
2019
By:
- Berger, Samantha E.;
- Huggins, Gordon S.;
- McCaffery, Jeanne M.;
- Jacques, Paul F.;
- Lichtenstein, Alice H.
Publication type:
journal article
Prevalence and Cumulative Risk of Familial Idiopathic Dilated Cardiomyopathy.
Published in:
2022
By:
- Huggins, Gordon S.;
- Kinnamon, Daniel D.;
- Haas, Garrie J.;
- Jordan, Elizabeth;
- Hofmeyer, Mark;
- Kransdorf, Evan;
- Ewald, Gregory A.;
- Morris, Alanna A.;
- Owens, Anjali;
- Lowes, Brian;
- Stoller, Douglas;
- Tang, W. H. Wilson;
- Garg, Sonia;
- Trachtenberg, Barry H.;
- Shah, Palak;
- Pamboukian, Salpy V.;
- Sweitzer, Nancy K.;
- Wheeler, Matthew T.;
- Wilcox, Jane E.;
- Katz, Stuart
Publication type:
journal article
Perinatal Natural History of the Ts1Cje Mouse Model of Down Syndrome: Growth Restriction, Early Mortality, Heart Defects, and Delayed Development.
Published in:
PLoS ONE, 2016, v. 11, n. 12, p. 1, doi. 10.1371/journal.pone.0168009
By:
- Ferrés, Millie A.;
- Bianchi, Diana W.;
- Siegel, Ashley E.;
- Bronson, Roderick T.;
- Huggins, Gordon S.;
- Guedj, Faycal
Publication type:
Article
The pathology and pathobiology of bicuspid aortic valve: State of the art and novel research perspectives.
Published in:
Journal of Pathology: Clinical Research, 2015, v. 1, n. 4, p. 195, doi. 10.1002/cjp2.21
By:
- Mathieu, Patrick;
- Bossé, Yohan;
- Huggins, Gordon S.;
- Della Corte, Alessandro;
- Pibarot, Philippe;
- Michelena, Hector I.;
- Limongelli, Giuseppe;
- Boulanger, Marie‐Chloé;
- Evangelista, Arturo;
- Bédard, Elisabeth;
- Citro, Rodolfo;
- Body, Simon C.;
- Nemer, Mona;
- Schoen, Frederick J.
Publication type:
Article
Cardiometabolic deaths attributable to poor diet among Kuwaiti adults.
Published in:
PLoS ONE, 2022, v. 17, n. 12, p. 1, doi. 10.1371/journal.pone.0279108
By:
- Al-Lahou, Badreya;
- Ausman, Lynne M.;
- Peñalvo, José L.;
- Huggins, Gordon S.;
- Zhang, Fang Fang
Publication type:
Article
CTSA Consortium Consensus Scientific Review Committee (SRC) Working Group Report on the SRC Processes.
Published in:
CTS: Clinical & Translational Science, 2015, v. 8, n. 6, p. 623, doi. 10.1111/cts.12306
By:
- Selker, Harry P.;
- Buse, John B.;
- Califf, Robert M.;
- Carter, Robert;
- Cooper, Dan M.;
- Davis, Jonathan;
- Ford, Daniel E.;
- Galassetti, Pietro;
- Guay‐Woodford, Lisa;
- Huggins, Gordon S.;
- Kasper, Amanda;
- Kieburtz, Karl;
- Kirby, Aaron;
- Klein, Andreas K.;
- Kline, Joel;
- O’ Neill, Robert T.;
- Rape, Marie;
- Reichgott, Douglas J.;
- Rojevsky, Svetlana;
- Rosenthal, Gary E.
Publication type:
Article
Identifying mitigating strategies for endothelial cell dysfunction and hypertension in response to VEGF receptor inhibitors.
Published in:
Clinical Science, 2024, v. 138, n. 18, p. 1131, doi. 10.1042/CS20240537
By:
- Camarda, Nicholas D.;
- Qing Lu;
- Meola, Dawn M.;
- Man, Joshua J.;
- Zeyuan Song;
- Travers, Richard J.;
- Lopez, Katherine E.;
- Powers, Sarah N.;
- Papanastasiou, Malvina;
- DeRuff, Katherine C.;
- Mullahoo, James;
- Egri, Shawn B.;
- Davison, Desiree;
- Sebastiani, Paola;
- Eblen, Scott T.;
- Buchsbaum, Rachel;
- Huggins, Gordon S.;
- London, Cheryl A.;
- Jaffe, Jacob D.;
- Upshaw, Jenica N.
Publication type:
Article
In-hospital measurement of left ventricular ejection fraction and one-year outcomes in acute coronary syndromes: results from the IMMEDIATE Trial.
Published in:
2016
By:
- Mukherjee, Jayanta T.;
- Beshansky, Joni R.;
- Ruthazer, Robin;
- Alkofide, Hadeel;
- Ray, Madhab;
- Kent, David;
- Manning, Warren J.;
- Huggins, Gordon S.;
- Selker, Harry P.
Publication type:
journal article
Lack of association of Klotho gene variants with valvular and vascular calcification in Caucasians: a candidate gene study of the Framingham Offspring Cohort.
Published in:
Nephrology Dialysis Transplantation, 2011, v. 26, n. 12, p. 3998, doi. 10.1093/ndt/gfr188
By:
- Tangri, Navdeep;
- Alam, Ahsan;
- Wooten, Eric C.;
- Huggins, Gordon S.
Publication type:
Article
Low-dose dopamine or low-dose nesiritide in acute heart failure with renal dysfunction: the ROSE acute heart failure randomized trial.
Published in:
2013
By:
- Chen, Horng H;
- Anstrom, Kevin J;
- Givertz, Michael M;
- Stevenson, Lynne W;
- Semigran, Marc J;
- Goldsmith, Steven R;
- Bart, Bradley A;
- Bull, David A;
- Stehlik, Josef;
- LeWinter, Martin M;
- Konstam, Marvin A;
- Huggins, Gordon S;
- Rouleau, Jean L;
- O'Meara, Eileen;
- Tang, W H Wilson;
- Starling, Randall C;
- Butler, Javed;
- Deswal, Anita;
- Felker, G Michael;
- O'Connor, Christopher M
Publication type:
journal article
Low-Dose Dopamine or Low-Dose Nesiritide in Acute Heart Failure With Renal Dysfunction.
Published in:
JAMA: Journal of the American Medical Association, 2013, v. 310, n. 23, p. 2533, doi. 10.1001/jama.2013.282190
By:
- Horng H. Chen;
- Anstrom, Kevin J.;
- Givertz, Michael M.;
- Stevenson, Lynne W.;
- Semigran, Marc J.;
- Goldsmith, Steven R.;
- Bart, Bradley A.;
- Bull, David A.;
- Stehlik, Josef;
- LeWinter, Martin M.;
- Konstam, Marvin A.;
- Huggins, Gordon S.;
- Rouleau, Jean L.;
- O'Meara, Eileen;
- Wilson Tang, W. H.;
- Starling, Randall C.;
- Butler, Javed;
- Deswal, Anita;
- Felker, G. Michael;
- O'Connor, Christopher M.
Publication type:
Article
Association of OPRM1 and COMT Single-Nucleotide Polymorphisms With Hospital Length of Stay and Treatment of Neonatal Abstinence Syndrome.
Published in:
JAMA: Journal of the American Medical Association, 2013, v. 309, n. 17, p. 1821, doi. 10.1001/jama.2013.3411
By:
- Wachman, Elisha M.;
- Hayes, Marie J.;
- Brown, Mark S.;
- Paul, Jonathan;
- Harvey-Wilkes, Karen;
- Terrin, Norma;
- Huggins, Gordon S.;
- Aranda, Jacob V.;
- Davis, Jonathan M.
Publication type:
Article
The Contribution of Lipids to the Interindividual Response of Vitamin K Biomarkers to Vitamin K Supplementation.
Published in:
Molecular Nutrition & Food Research, 2019, v. 63, n. 24, p. N.PAG, doi. 10.1002/mnfr.201900399
By:
- Kelly, Jennifer M.;
- Ordovas, Jose M.;
- Matuszek, Gregory;
- Smith, Caren E.;
- Huggins, Gordon S.;
- Dashti, Hassan S.;
- Ichikawa, Reiko;
- Booth, Sarah L.
Publication type:
Article
C-Reactive protein reactions to glucose-insulin-potassium infusion and relations to infarct size in patients with acute coronary syndromes.
Published in:
2015
By:
- Alkofide, Hadeel;
- Huggins, Gordon S.;
- Beshansky, Joni R.;
- Ruthazer, Robin;
- Peter, Inga;
- Ray, Madhab;
- Mukherjee, Jayanta T.;
- Selker, Harry P.
Publication type:
journal article
Human Cardiovascular Disease IBC Chip-Wide Association with Weight Loss and Weight Regain in the Look AHEAD Trial.
Published in:
Human Heredity, 2013, v. 75, n. 2-4, p. 160, doi. 10.1159/000353181
By:
- McCaffery, Jeanne M.;
- Papandonatos, George D.;
- Huggins, Gordon S.;
- Peter, Inga;
- Erar, Bahar;
- Kahn, Steven E.;
- Knowler, William C.;
- Lipkin, Edward W.;
- Kitabchi, Abbas E.;
- Wagenknecht, Lynne E.;
- Wing, Rena R.
Publication type:
Article
Individualized interactomes for network-based precision medicine in hypertrophic cardiomyopathy with implications for other clinical pathophenotypes.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-21146-y
By:
- Maron, Bradley A.;
- Wang, Rui-Sheng;
- Shevtsov, Sergei;
- Drakos, Stavros G.;
- Arons, Elena;
- Wever-Pinzon, Omar;
- Huggins, Gordon S.;
- Samokhin, Andriy O.;
- Oldham, William M.;
- Aguib, Yasmine;
- Yacoub, Magdi H.;
- Rowin, Ethan J.;
- Maron, Barry J.;
- Maron, Martin S.;
- Loscalzo, Joseph
Publication type:
Article
Conditional deletion of RB1 in the Tie2 lineage leads to aortic valve regurgitation.
Published in:
PLoS ONE, 2018, v. 13, n. 1, p. 1, doi. 10.1371/journal.pone.0190623
By:
- Freytsis, Marina;
- Baugh, Lauren;
- Liu, Zhiyi;
- Georgakoudi, Irene;
- Hinds, Philip W.;
- Black, Lauren D.;
- Huggins, Gordon S.
Publication type:
Article
Response to Comment on The Look AHEAD Research Group. Prospective Association of GLUL rs10911021 With Cardiovascular Morbidity and Mortality Among Individuals With Type 2 Diabetes: The Look AHEAD Study. Diabetes 2016;65:297-302.
Published in:
2016
By:
- McCaffery, Jeanne M.;
- Huggins, Gordon S.
Publication type:
Letter
Genetic Predisposition to Weight Loss and Regain With Lifestyle Intervention: Analyses From the Diabetes Prevention Program and the Look AHEAD Randomized Controlled Trials.
Published in:
2015
By:
- Papandonatos, George D.;
- Qing Pan;
- Pajewski, Nicholas M.;
- Delahanty, Linda M.;
- Peter, Inga;
- Erar, Bahar;
- Ahmad, Shafqat;
- Harden, Maegan;
- Ling Chen;
- Fontanillas, Pierre;
- Wagenknecht, Lynne E.;
- Kahn, Steven E.;
- Wing, Rena R.;
- Jablonski, Kathleen A.;
- Huggins, Gordon S.;
- Knowler, William C.;
- Florez, Jose C.;
- McCaffery, Jeanne M.;
- Franks, Paul W.;
- Pan, Qing
Publication type:
journal article
ANGPTL4 variants E40K and T266M are associated with lower fasting triglyceride levels in Non-Hispanic White Americans from the Look AHEAD Clinical Trial.
Published in:
BMC Medical Genetics, 2011, v. 12, n. 1, p. 89, doi. 10.1186/1471-2350-12-89
By:
- Smart-Halajko, Melissa C.;
- Kelley-Hedgepeth, Alyson;
- Montefusco, Maria Claudia;
- Cooper, Jackie A.;
- Kopin, Alan;
- McCaffrey, Jeanne M.;
- Balasubramanyam, Ashok;
- Pownall, Henry J.;
- Nathan, David M.;
- Peter, Inga;
- Talmud, Philippa J.;
- Huggins, Gordon S.
Publication type:
Article

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