Works by Hueng-Sik Choi

Results: 74

Orphan nuclear receptor ERRγ regulates hepatic TGF-β2 expression and fibrogenic response in CCl<sub>4</sub>-induced acute liver injury.

Published in:

Archives of Toxicology, 2021, v. 95, n. 9, p. 3071, doi. 10.1007/s00204-021-03112-1

By:

Jung, Yoon Seok;
Kim, Yong-Hoon;
Radhakrishnan, Kamalakannan;
Kim, Jina;
Lee, In-Kyu;
Cho, Sung Jin;
Kim, Don-Kyu;
Dooley, Steven;
Lee, Chul-Ho;
Choi, Hueng-Sik

Publication type:

Article

An inverse agonist of estrogen-related receptor γ regulates 2-arachidonoylglycerol synthesis by modulating diacylglycerol lipase expression in alcohol-intoxicated mice.

Published in:

Archives of Toxicology, 2020, v. 94, n. 2, p. 427, doi. 10.1007/s00204-019-02648-7

By:

Jung, Yoon Seok;
Kim, Yong-Hoon;
Radhakrishnan, Kamalakannan;
kim, Jina;
Kim, Don-Kyu;
Lee, Ji-Hyeok;
Oh, Hyunhee;
Lee, In-Kyu;
Kim, Wook;
Cho, Sung Jin;
Choi, Cheol Soo;
Dooley, Steven;
Egan, Josephine M.;
Lee, Chul-Ho;
Choi, Hueng-Sik

Publication type:

Article

Hepatocyte CREBH deficiency aggravates inflammatory liver injury following chemokine-dependent neutrophil infiltration through upregulation of NF-κB p65 in mice.

Published in:

Archives of Toxicology, 2020, v. 94, n. 2, p. 509, doi. 10.1007/s00204-019-02633-0

By:

Noh, Jung-Ran;
Kim, Jae-Hoon;
Na, Soon-Young;
Lee, In Bok;
Seo, Yun Jeong;
Choi, Jung Hyeon;
Seo, Youngwon;
Lee, Tae Geol;
Choi, Hueng-Sik;
Kim, Yong-Hoon;
Lee, Chul-Ho

Publication type:

Article

Inverse agonist of ERRγ reduces cannabinoid receptor type 1-mediated induction of fibrinogen synthesis in mice with a high-fat diet-intoxicated liver.

Published in:

Archives of Toxicology, 2018, v. 92, n. 9, p. 2885, doi. 10.1007/s00204-018-2270-4

By:

Zhang, Yaochen;
Kim, Don-Kyu;
Jung, Yoon Seok;
Kim, Yong-Hoon;
Lee, Yong Soo;
Kim, Jina;
Jeong, Won-IL;
Lee, In-Kyu;
Cho, Sung Jin;
Dooley, Steven;
Lee, Chul-Ho;
Choi, Hueng-Sik

Publication type:

Article

Hepatocyte SHP deficiency protects mice from acetaminophen-evoked liver injury in a JNK-signaling regulation and GADD45β-dependent manner.

Published in:

Archives of Toxicology, 2018, v. 92, n. 8, p. 2563, doi. 10.1007/s00204-018-2247-3

By:

Kim, Yong-Hoon;
Noh, Jung-Ran;
Hwang, Jung Hwan;
Kim, Kyoung-Shim;
Choi, Dong-Hee;
Kim, Jae-Hoon;
Moon, Sung Je;
Choi, Ji Hyun;
Hérault, Yann;
Lee, Tae Geol;
Choi, Hueng-Sik;
Lee, Chul-Ho

Publication type:

Article

Transcriptional corepressor SHP recruits SIRT1 histone deacetylase to inhibit LRH-1 transactivation.

Published in:

Nucleic Acids Research, 2010, v. 38, n. 14, p. 4607, doi. 10.1093/nar/gkq227

By:

Chanda, Dipanjan;
Xie, Yuan-Bin;
Choi, Hueng-Sik

Publication type:

Article

Molecular characterization of SMILE as a novel corepressor of nuclear receptors.

Published in:

Nucleic Acids Research, 2009, v. 37, n. 12, p. 4100, doi. 10.1093/nar/gkp333

By:

Xie, Yuan-Bin;
Nedumaran, Balachandar;
Choi, Hueng-Sik

Publication type:

Article

An autoregulatory loop controlling orphan nuclear receptor DAX-1 gene expression by orphan nuclear receptor ERRγ.

Published in:

Nucleic Acids Research, 2005, v. 33, n. 21, p. 6756, doi. 10.1093/nar/gki976

By:

Park, Yun-Yong;
Ahn, Seung-Won;
Kim, Hye-Jin;
Kim, Jin-Man;
Lee, In-Kyu;
Kang, Heonjoong;
Choi, Hueng-Sik

Publication type:

Article

Synergistic activation of the human orphan nuclear receptor SHP gene promoter by basic helix–loop–helix protein E2A and orphan nuclear receptor SF‐1.

Published in:

Nucleic Acids Research, 2003, v. 31, n. 23, p. 6860, doi. 10.1093/nar/gkg906

By:

Kim, Han‐Jong;
Kim, Joon‐Young;
Park, Yun‐Yong;
Choi, Hueng‐Sik

Publication type:

Article

Leydig Cell–Specific DAX1-Deleted Mice Has Higher Testosterone Level in the Testis During Pubertal Development.

Published in:

Reproductive Sciences, 2022, v. 29, n. 3, p. 955, doi. 10.1007/s43032-021-00554-x

By:

Kumar, Sudeep;
Kim, Hyo Jeong;
Lee, Chul-Ho;
Choi, Hueng-Sik;
Lee, Keesook

Publication type:

Article

Hippo-mediated suppression of IRS2/AKT signaling prevents hepatic steatosis and liver cancer.

Published in:

2018

By:

Sun-Hye Jeong;
Han-Byul Kim;
Min-Chul Kim;
Ji-min Lee;
Jae Ho Lee;
Jeong-Hwan Kim;
Jin-Woo Kim;
Woong-Yang Park;
Seon-Young Kim;
Jae Bum Kim;
Haeryoung Kim;
Jin-Man Kim;
Hueng-Sik Choi;
Dae-Sik Lim;
Jeong, Sun-Hye;
Kim, Han-Byul;
Kim, Min-Chul;
Lee, Ji-Min;
Lee, Jae Ho;
Kim, Jeong-Hwan

Publication type:

journal article

The Orphan Nuclear Receptor ERRγ Regulates Hepatic CB1 Receptor-Mediated Fibroblast Growth Factor 21 Gene Expression.

Published in:

PLoS ONE, 2016, v. 11, n. 7, p. 1, doi. 10.1371/journal.pone.0159425

By:

Jung, Yoon Seok;
Lee, Ji-Min;
Kim, Don-Kyu;
Lee, Yong-Soo;
Kim, Ki-Sun;
Kim, Yong-Hoon;
Kim, Jina;
Lee, Myung-Shik;
Lee, In-Kyu;
Kim, Seong Heon;
Cho, Sung Jin;
Jeong, Won-Il;
Lee, Chul-Ho;
Harris, Robert A.;
Choi, Hueng-Sik

Publication type:

Article

Frontline Science: Estrogen‐related receptor γ increases poly(I:C)‐mediated type I IFN expression in mouse macrophages.

Published in:

Journal of Leukocyte Biology, 2021, v. 109, n. 5, p. 865, doi. 10.1002/JLB.2HI1219-762R

By:

Kim, Ki‐Sun;
Kim, Don‐Kyu;
Na, Soon‐Young;
Jung, Yoon Seok;
Cho, Sung Jin;
Kim, Jina;
Lee, In‐Kyu;
Kim, Young‐Hoon;
Lee, Chul‐Ho;
Jeong, Won‐Il;
Jo, Eun‐Kyeong;
Choi, Hueng‐Sik

Publication type:

Article

Emerging Role of SMILE in Liver Metabolism.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 3, p. 2907, doi. 10.3390/ijms24032907

By:

Sadasivam, Nanthini;
Radhakrishnan, Kamalakannan;
Choi, Hueng-Sik;
Kim, Don-Kyu

Publication type:

Article

An Inverse Agonist GSK5182 Increases Protein Stability of the Orphan Nuclear Receptor ERRγ via Inhibition of Ubiquitination.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 1, p. 96, doi. 10.3390/ijms24010096

By:

Na, Soon-Young;
Kim, Ki-Sun;
Jung, Yoon Seok;
Kim, Don-Kyu;
Kim, Jina;
Cho, Sung Jin;
Lee, In-Kyu;
Chung, Jongkyeong;
Kim, Jeong-Sun;
Choi, Hueng-Sik

Publication type:

Article

SMILE Downregulation during Melanogenesis Induces MITF Transcription in B16F10 Cells.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 23, p. 15094, doi. 10.3390/ijms232315094

By:

Truong, Xuan T.;
Lee, Young-Seung;
Nguyen, Thuy T. P.;
Kim, Hyun-Jin;
Kim, Sung-Hak;
Moon, Changjong;
Kim, Don-Kyu;
Choi, Hueng-Sik;
Jeon, Tae-Il

Publication type:

Article

Hepatocyte DAX1 Deletion Exacerbates Inflammatory Liver Injury by Inducing the Recruitment of CD4 + and CD8 + T Cells through NF-κB p65 Signaling Pathway in Mice.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 22, p. 14009, doi. 10.3390/ijms232214009

By:

Yun, Hyo-Jeong;
Suh, Young-Joo;
Kim, Yu-Bin;
Kang, Eun-Jung;
Choi, Jung Hyeon;
Choi, Young-Keun;
Lee, In-Bok;
Choi, Dong-Hee;
Seo, Yun Jeong;
Noh, Jung-Ran;
Choi, Hueng-Sik;
Kim, Yong-Hoon;
Lee, Chul-Ho

Publication type:

Article

Melatonin Regulates Iron Homeostasis by Inducing Hepcidin Expression in Hepatocytes.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 7, p. 3593, doi. 10.3390/ijms23073593

By:

Park, Woo-Ram;
Choi, Byungyoon;
Kim, Yu-Ji;
Kim, Yong-Hoon;
Park, Min-Jung;
Kim, Dong-Il;
Choi, Hueng-Sik;
Kim, Don-Kyu

Publication type:

Article

Orphan Nuclear Receptor ERRγ Is a Transcriptional Regulator of CB1 Receptor-Mediated TFR2 Gene Expression in Hepatocytes.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 11, p. 6021, doi. 10.3390/ijms22116021

By:

Kim, Bo-Eun;
Choi, Byungyoon;
Park, Woo-Ram;
Kim, Yu-Ji;
Kim, In-Young;
Jung, Yoon Seok;
Kim, Yong-Hoon;
Lee, Chul-Ho;
Choi, Hueng-Sik;
Kim, Don-Kyu

Publication type:

Article

Orphan Nuclear Receptor ERRγ Is a Novel Transcriptional Regulator of IL-6 Mediated Hepatic BMP6 Gene Expression in Mice.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 19, p. 7148, doi. 10.3390/ijms21197148

By:

Radhakrishnan, Kamalakannan;
Kim, Yong-Hoon;
Jung, Yoon Seok;
Kim, Jina;
Kim, Don-Kyu;
Cho, Sung Jin;
Lee, In-Kyu;
Dooley, Steven;
Lee, Chul-Ho;
Choi, Hueng-Sik

Publication type:

Article

Orphan nuclear receptor ERRγ is a key regulator of human fibrinogen gene expression.

Published in:

PLoS ONE, 2017, v. 12, n. 7, p. 1, doi. 10.1371/journal.pone.0182141

By:

Zhang, Yaochen;
Kim, Don-Kyu;
Lu, Yan;
Jung, Yoon Seok;
Lee, Ji-min;
Kim, Young-Hoon;
Lee, Yong Soo;
Kim, Jina;
Dewidar, Bedair;
Jeong, Won-IL;
Lee, In-Kyu;
Cho, Sung Jin;
Dooley, Steven;
Lee, Chul-Ho;
Li, Xiaoying;
Choi, Hueng-Sik

Publication type:

Article

eIF2α phosphorylation is required to prevent hepatocyte death and liver fibrosis in mice challenged with a high fructose diet.

Published in:

Nutrition & Metabolism, 2017, v. 14, p. 1, doi. 10.1186/s12986-017-0202-6

By:

Woo-Gyun Choi;
Jaeseok Han;
Ji-Hyeon Kim;
Mi-Jeong Kim;
Jae-Woo Park;
Benbo Song;
Hee-Jeong Cha;
Hye-Seon Choi;
Hun-Taeg Chung;
In-Kyu Lee;
Tae-Sik Park;
Hatzoglou, Maria;
Hueng-Sik Choi;
Hyun Ju Yoo;
Kaufman, Randal J.;
Sung Hoon Back

Publication type:

Article

Estrogen-related receptor gamma regulates dopaminergic neuronal phenotype by activating GSK3β/ NFAT signaling in SH- SY5Y cells.

Published in:

Journal of Neurochemistry, 2015, v. 133, n. 4, p. 544, doi. 10.1111/jnc.13085

By:

Lim, Juhee;
Choi, Hueng‐Sik;
Choi, Hyun Jin

Publication type:

Article

PKB/Akt phosphorylation of ERRγ contributes to insulin-mediated inhibition of hepatic gluconeogenesis.

Published in:

Diabetologia, 2014, v. 57, n. 12, p. 2576, doi. 10.1007/s00125-014-3366-x

By:

Kim, Don-Kyu;
Kim, Yong-Hoon;
Hynx, Debby;
Wang, Yanning;
Yang, Keum-Jin;
Ryu, Dongryeol;
Kim, Kyung;
Yoo, Eun-Kyung;
Kim, Jeong-Sun;
Koo, Seung-Hoi;
Lee, In-Kyu;
Chae, Ho-Zoon;
Park, Jongsun;
Lee, Chul-Ho;
Biddinger, Sudha;
Hemmings, Brian;
Choi, Hueng-Sik

Publication type:

Article

The orphan nuclear receptor SHP acts as a negative regulator in inflammatory signaling triggered by Toll-like receptors.

Published in:

Nature Immunology, 2011, v. 12, n. 8, p. 742, doi. 10.1038/ni.2064

By:

Yuk, Jae-Min;
Shin, Dong-Min;
Lee, Hye-Mi;
Kim, Jwa-Jin;
Kim, Sun-Woong;
Jin, Hyo Sun;
Yang, Chul-Su;
Park, Kyeong Ah;
Chanda, Dipanjan;
Kim, Don-Kyu;
Huang, Song Mei;
Lee, Sang Ki;
Lee, Chul-Ho;
Kim, Jin-Man;
Song, Chang-Hwa;
Lee, Soo Young;
Hur, Gang Min;
Moore, David D;
Choi, Hueng-Sik;
Jo, Eun-Kyeong

Publication type:

Article

Small heterodimer partner negatively regulates C-X-C motif chemokine ligand 2 in hepatocytes during liver inflammation.

Published in:

Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-33660-z

By:

Noh, Jung-Ran;
Kim, Yong-Hoon;
Kim, Don-Kyu;
Hwang, Jung Hwan;
Kim, Kyoung-Shim;
Choi, Dong-Hee;
Lee, Seon-Jin;
Lee, Hee Gu;
Lee, Tae Geol;
Weng, Hong-Lei;
Dooley, Steven;
Choi, Hueng-Sik;
Lee, Chul-Ho

Publication type:

Article

Small heterodimer partner interacts with NLRP3 and negatively regulates activation of the NLRP3 inflammasome.

Published in:

Nature Communications, 2015, v. 6, n. 2, p. 6115, doi. 10.1038/ncomms7115

By:

Yang, Chul-Su;
Kim, Jwa-Jin;
Kim, Tae Sung;
Lee, Phil Young;
Kim, Soo Yeon;
Lee, Hye-Mi;
Shin, Dong-Min;
Nguyen, Loi T.;
Lee, Moo-Seung;
Jin, Hyo Sun;
Kim, Kwang-Kyu;
Lee, Chul-Ho;
Kim, Myung Hee;
Park, Sung Goo;
Kim, Jin-Man;
Choi, Hueng-Sik;
Jo, Eun-Kyeong

Publication type:

Article

Corrigendum: The adipokine Retnla modulates cholesterol homeostasis in hyperlipidemic mice.

Published in:

Nature Communications, 2015, v. 6, n. 1, p. 6076, doi. 10.1038/ncomms7076

By:

Lee, Mi-Ran;
Lim, Chae-ji;
Lee, You-Han;
Park, Jong-Gil;
Sonn, Seong Keun;
Lee, Mi-Ni;
Jung, In-Hyuk;
Jeong, Se-Jin;
Jeon, Sejin;
Lee, Myoungsook;
Oh, Ki Sook;
Yang, Young;
Kim, Jae Bum;
Choi, Hueng-Sik;
Jeong, Woojin;
Jeong, Tae-Sook;
Yoon, Won Kee;
Kim, Hyoung Chin;
Choi, Jae-Hoon;
Oh, Goo Taeg

Publication type:

Article

The adipokine Retnla modulates cholesterol homeostasis in hyperlipidemic mice.

Published in:

Nature Communications, 2014, v. 5, n. 7, p. 4410, doi. 10.1038/ncomms5410

By:

Lee, Mi-Ran;
Lim, Chae-ji;
Lee, You-Han;
Park, Jong-Gil;
Sonn, Seong Keun;
Lee, Mi-Ni;
Jung, In-Hyuk;
Jeong, Se-Jin;
Jeon, Sejin;
Lee, Myoungsook;
Oh, Ki Sook;
Yang, Young;
Kim, Jae Bum;
Choi, Hueng-Sik;
Jeong, Woojin;
Jeong, Tae-Sook;
Yoon, Won Kee;
Kim, Hyoung Chin;
Choi, Jae-Hoon;
Oh, Goo Taeg

Publication type:

Article

ESRRA (estrogen-related receptor α) is a key coordinator of transcriptional and post-translational activation of autophagy to promote innate host defense.

Published in:

Autophagy, 2018, v. 14, n. 1, p. 152, doi. 10.1080/15548627.2017.1339001

By:

Kim, Soo Yeon;
Yang, Chul-Su;
Lee, Hye-Mi;
Kim, Jin Kyung;
Kim, Yi-Sak;
Kim, Ye-Ram;
Kim, Jae-Sung;
Kim, Tae Sung;
Yuk, Jae-Min;
Dufour, Catherine Rosa;
Lee, Sang-Hee;
Kim, Jin-Man;
Choi, Hueng-Sik;
Giguère, Vincent;
Jo, Eun-Kyeong

Publication type:

Article

Therapeutic strategy targeting host lipolysis limits infection by SARS-CoV-2 and influenza A virus.

Published in:

Signal Transduction & Targeted Therapy, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41392-022-01223-4

By:

Baek, Yeong-Bin;
Kwon, Hyung-Jun;
Sharif, Muhammad;
Lim, Jeongah;
Lee, In-Chul;
Ryu, Young Bae;
Lee, Jae-In;
Kim, Ji-Sun;
Lee, Young-Seung;
Kim, Dong-Hoon;
Park, Sang-Ik;
Kim, Don-Kyu;
Kim, Jeong-Sun;
Choy, Hyon E.;
Lee, Sunwoo;
Choi, Hueng-Sik;
Osborne, Timothy F.;
Jeon, Tae-Il;
Cho, Kyoung-Oh

Publication type:

Article

Epigallocatechin-3-Gallate Suppresses BMP-6-Mediated SMAD1/5/8 Transactivation of Hepcidin Gene by Inducing SMILE in Hepatocytes.

Published in:

Antioxidants, 2021, v. 10, n. 10, p. 1590, doi. 10.3390/antiox10101590

By:

Kim, Yu-Ji;
Park, Woo-Ram;
Choi, Byungyoon;
Choi, Hueng-Sik;
Kim, Don-Kyu

Publication type:

Article

Epigallocatechin-3-Gallate (EGCG)-Inducible SMILE Inhibits STAT3-Mediated Hepcidin Gene Expression.

Published in:

Antioxidants, 2020, v. 9, n. 6, p. 514, doi. 10.3390/antiox9060514

By:

Kim, Yu-Ji;
Kim, Ki-Sun;
Lim, Daejin;
Yang, Dong Ju;
Park, Jae-Il;
Kim, Ki Woo;
Jeong, Jae-Ho;
Choi, Hueng-Sik;
Kim, Don-Kyu

Publication type:

Article

autoregulatory loop controlling orphan nuclear receptor DAX-1 gene expression by orphan nuclear receptor ERRγ.

Published in:

Nucleic Acids Research, 2019, v. 47, n. 3, p. 1604, doi. 10.1093/nar/gky1272

By:

Park, Yun-Yong;
Ahn, Seung-Won;
Kim, Hye-Jin;
Kim, Jin-Man;
Lee, In-Kyu;
Kang, Heonjoong;
Choi, Hueng-Sik

Publication type:

Article

An autoregulatory loop controlling orphan nuclear receptor DAX-1 gene expression by orphan nuclear receptor ERRγ.

Published in:

Nucleic Acids Research, 2018, v. 46, n. 22, p. 12192, doi. 10.1093/nar/gky1145

By:

Park, Yun-Yong;
Ahn, Seung-Won;
Kim, Hye-Jin;
Kim, Jin-Man;
Lee, In-Kyu;
Kang, Heonjoong;
Choi, Hueng-Sik

Publication type:

Article

RORα switches transcriptional mode of ERRγ that results in transcriptional repression of CYP2E1 under ethanol-exposure.

Published in:

Nucleic Acids Research, 2016, v. 44, n. 3, p. 1095, doi. 10.1093/nar/gkv1034

By:

Yong-Hyun Han;
Don-Kyu Kim;
Tae-Young Na;
Na-Lee Ka;
Hueng-Sik Choi;
Mi-Ock Lee

Publication type:

Article

Transcriptional cross talk between orphan nuclear receptor ERRγ and transmembrane transcription factor ATF6α coordinates endoplasmic reticulum stress response.

Published in:

Nucleic Acids Research, 2013, v. 41, n. 14, p. 6960, doi. 10.1093/nar/gkt429

By:

Misra, Jagannath;
Kim, Don-Kyu;
Choi, Woogyun;
Koo, Seung-Hoi;
Lee, Chul-Ho;
Back, Sung-Hoon;
Kaufman, Randal J.;
Choi, Hueng-Sik

Publication type:

Article

Author Correction: Estrogen-related receptor gamma functions as a tumor suppressor in gastric cancer.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-06061-z

By:

Kang, Myoung-Hee;
Choi, Hyunji;
Oshima, Masanobu;
Cheong, Jae-Ho;
Kim, Seokho;
Lee, Jung Hoon;
Park, Young Soo;
Choi, Hueng-Sik;
Kweon, Mi-Na;
Pack, Chan-Gi;
Lee, Ju-Seog;
Mills, Gordon B.;
Myung, Seung-Jae;
Park, Yun-Yong

Publication type:

Article

The hepcidin-ferroportin axis controls the iron content of Salmonella-containing vacuoles in macrophages.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04446-8

By:

Daejin Lim;
Kwang Soo Kim;
Jae-Ho Jeong;
Marques, Oriana;
Hyun-Ju kim;
Miryoung Song;
Tae-Hoon Lee;
Jae Il Kim;
Hueng-Sik Choi;
Jung-Joon Min;
Bumann, Dirk;
Muckenthaler, Martina U.;
Choy, Hyon E.

Publication type:

Article

Estrogen-related receptor gamma functions as a tumor suppressor in gastric cancer.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41467-018-04244-2

By:

Kang, Myoung-Hee;
Choi, Hyunji;
Oshima, Masanobu;
Cheong, Jae-Ho;
Kim, Seokho;
Lee, Jung Hoon;
Park, Young Soo;
Choi, Hueng-Sik;
Kweon, Mi-Na;
Pack, Chan-Gi;
Lee, Ju-Seog;
Mills, Gordon B.;
Myung, Seung-Jae;
Park, Yun-Yong

Publication type:

Article

Estrogen-related receptor γ causes osteoarthritis by upregulating extracellular matrix-degrading enzymes.

Published in:

Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-01868-8

By:

Young-Ok Son;
Seulki Park;
Ji-Sun Kwak;
Yoonkyung Won;
Wan-Su Choi;
Jinseol Rhee;
Churl-Hong Chun;
Je-Hwang Ryu;
Don-Kyu Kim;
Hueng-Sik Choi;
Jang-Soo Chun

Publication type:

Article

The Orphan Nuclear Receptor SHP Is a Positive Regulator of Osteoblastic Bone Formation.

Published in:

Journal of Bone & Mineral Research, 2010, v. 25, n. 2, p. 262, doi. 10.1359/jbmr.090718

By:

Byung-Chul Jeong;
Yong-Soo Lee;
In-Ho Bae;
Chul-Ho Lee;
Hong-ln Shin;
Hyun Jung Ha;
Renny T. Franceschi;
Hueng-Sik Choi;
Jeong-Tae Koh

Publication type:

Article

O-GlcNAcylation of Orphan Nuclear Receptor Estrogen-Related Receptor γ Promotes Hepatic Gluconeogenesis.

Published in:

2016

By:

Jagannath Misra;
Don-Kyu Kim;
Yoon Seok Jung;
Han Byeol Kim;
Yong-Hoon Kim;
Eun-Kyung Yoo;
Byung Gyu Kim;
Sunghoon Kim;
In-Kyu Lee;
Harris, Robert A.;
Jeong-Sun Kim;
Chul-Ho Lee;
Jin Won Cho;
Hueng-Sik Choi;
Misra, Jagannath;
Kim, Don-Kyu;
Jung, Yoon Seok;
Kim, Han Byeol;
Kim, Yong-Hoon;
Yoo, Eun-Kyung

Publication type:

journal article

Insulin-Inducible SMILE Inhibits Hepatic Gluconeogenesis.

Published in:

2016

By:

Ji-Min Lee;
Woo-Young Seo;
Hye-Sook Han;
Kyoung-Jin Oh;
Yong-Soo Lee;
Don-Kyu Kim;
Seri Choi;
Byeong Hun Choi;
Harris, Robert A.;
Chul-Ho Lee;
Seung-Hoi Koo;
Hueng-Sik Choi;
Lee, Ji-Min;
Seo, Woo-Young;
Han, Hye-Sook;
Oh, Kyoung-Jin;
Lee, Yong-Soo;
Kim, Don-Kyu;
Choi, Seri;
Choi, Byeong Hun

Publication type:

journal article

B-Cell Translocation Gene 2 Regulates Hepatic Glucose Homeostasis via Induction of Orphan Nuclear Receptor Nur77 in Diabetic Mouse Model.

Published in:

Diabetes, 2014, v. 63, n. 6, p. 1870, doi. 10.2337/db13-1368

By:

Yong Deuk Kim;
Sun-Gyun Kim;
Seung-Lark Hwang;
Hueng-Sik Choi;
Jae-Hoon Bae;
Dae-Kyu Song;
Seung-Soon Im

Publication type:

Article

Inverse agonist of nuclear receptor ERRγ mediates antidiabetic effect through inhibition of hepatic gluconeogenesis.

Published in:

2013

By:

Kim, Don-Kyu;
Gang, Gil-Tae;
Ryu, Dongryeol;
Koh, Minseob;
Kim, Yo-Na;
Kim, Su Sung;
Park, Jinyoung;
Kim, Yong-Hoon;
Sim, Taebo;
Lee, In-Kyu;
Choi, Cheol Soo;
Park, Seung Bum;
Lee, Chul-Ho;
Koo, Seung-Hoi;
Choi, Hueng-Sik

Publication type:

journal article

Inverse Agonist of Nuclear Receptor ERRγ Mediates Antidiabetic Effect Through Inhibition of Hepatic Gluconeogenesis.

Published in:

Diabetes, 2013, v. 62, n. 9, p. 3093, doi. 10.2337/db12-0946

By:

Don-Kyu Kim;
Gil-Tae Gang;
Dongryeol Ryu;
Minseob Koh;
Yo-Na Kim;
Su Sung Kim;
Jinyoung Park;
Yong-Hoon Kim;
Taebo Sim;
In-Kyu Lee;
Cheol Soo Choi;
Seung Bum Park;
Chul-Ho Lee;
Seung-Hoi Koo;
Hueng-Sik Choi

Publication type:

Article

Disruption of the cereblon gene enhances hepatic AMPK activity and prevents high-fat diet-induced obesity and insulin resistance in mice.

Published in:

2013

By:

Lee, Kwang Min;
Yang, Seung-Joo;
Kim, Yong Deuk;
Choi, Yoo Duk;
Nam, Jong Hee;
Choi, Cheol Soo;
Choi, Hueng-Sik;
Park, Chul-Seung

Publication type:

journal article

Disruption of the Cereblon Gene Enhances Hepatic AMPK Activity and Prevents High-Fat Diet--Induced Obesity and Insulin Resistance in Mice.

Published in:

Diabetes, 2013, v. 62, n. 6, p. 1855, doi. 10.2337/db12-1030

By:

Kwang Min Lee;
Seung-Joo Yang;
Yong Deuk Kim;
Yoo Duk Choi;
Jong Hee Nam;
Cheol Soo Choi;
Hueng-Sik Choi;
Chul-Seung Park

Publication type:

Article

Metformin Inhibits Growth Hormone--Mediated Hepatic PDK4 Gene Expression Through Induction of Orphan Nuclear Receptor Small Heterodimer Partner.

Published in:

Diabetes, 2012, v. 61, n. 10, p. 2484, doi. 10.2337/db11-1665

By:

Yong Deuk Kim;
Yong-Hoon Kim;
Tadi, Surendar;
Ji Hoon Yu;
Yong-Hyeon Yim;
Nam Ho Jeoung;
Minho Shong;
Hennighausen, Lothar;
Harris, Robert A.;
In-Kyu Lee;
Chul-Ho Lee;
Hueng-Sik Choi

Publication type:

Article