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LAG-3, TIM-3 and VISTA Expression on Tumor-Infiltrating Lymphocytes in Oropharyngeal Squamous Cell Carcinoma—Potential Biomarkers for Targeted Therapy Concepts.
Published in:
International Journal of Molecular Sciences, 2021, v. 22, n. 1, p. 379, doi. 10.3390/ijms22010379
By:
- Wuerdemann, Nora;
- Pütz, Katharina;
- Eckel, Hans;
- Jain, Rishabh;
- Wittekindt, Claus;
- Huebbers, Christian U.;
- Sharma, Shachi J.;
- Langer, Christine;
- Gattenlöhner, Stefan;
- Büttner, Reinhard;
- Speel, Ernst-Jan;
- Suchan, Malte;
- Wagner, Steffen;
- Quaas, Alexander;
- Klussmann, Jens P.
Publication type:
Article
PD-L1 Expression and a High Tumor Infiltrate of CD8+ Lymphocytes Predict Outcome in Patients with Oropharyngeal Squamous Cells Carcinoma.
Published in:
International Journal of Molecular Sciences, 2020, v. 21, n. 15, p. 5228, doi. 10.3390/ijms21155228
By:
- Wuerdemann, Nora;
- Gültekin, Sibel E.;
- Pütz, Katharina;
- Wittekindt, Claus;
- Huebbers, Christian U.;
- Sharma, Shachi J.;
- Eckel, Hans;
- Schubotz, Anna B.;
- Gattenlöhner, Stefan;
- Büttner, Reinhard;
- Speel, Ernst-Jan;
- Klussmann, Jens P.;
- Wagner, Steffen;
- Quaas, Alexander
Publication type:
Article
Proximity ligation‐based sequencing for the identification of human papillomavirus genomic integration sites in formalin‐fixed paraffin embedded oropharyngeal squamous cell carcinomas.
Published in:
Journal of Medical Virology, 2024, v. 96, n. 8, p. 1, doi. 10.1002/jmv.29837
By:
- Demers, Imke;
- Balaji, Harini;
- Feitsma, Harma;
- Stelloo, Ellen;
- Swennenhuis, Joost;
- Sergeeva, Irina;
- Wuerdemann, Nora;
- van den Hout, Mari F. C. M.;
- Wagner, Steffen;
- Kremer, Bernd;
- Klussmann, Jens P.;
- Huebbers, Christian U.;
- Speel, Ernst‐Jan M.
Publication type:
Article
Valosin-Containing Protein (VCP/p97)-Expression Correlates with Prognosis of HPV- Negative Oropharyngeal Squamous Cell Carcinoma (OSCC).
Published in:
PLoS ONE, 2014, v. 9, n. 12, p. 1, doi. 10.1371/journal.pone.0114170
By:
- Meyer, Moritz F.;
- Seuthe, Inga M. C.;
- Drebber, Uta;
- Siefer, Oliver;
- Kreppel, Matthias;
- Klein, Marcus O.;
- Mikolajczak, Stefanie;
- Klussmann, Jens Peter;
- Preuss, Simon F.;
- Huebbers, Christian U.
Publication type:
Article
Comprehensive Analysis of HPV16 Integration in OSCC Reveals No Significant Impact of Physical Status on Viral Oncogene and Virally Disrupted Human Gene Expression.
Published in:
PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0088718
By:
- Olthof, Nadine C.;
- Speel, Ernst-Jan M.;
- Kolligs, Jutta;
- Haesevoets, Annick;
- Henfling, Mieke;
- Ramaekers, Frans C. S.;
- Preuss, Simon F.;
- Drebber, Uta;
- Wieland, Ulrike;
- Silling, Steffi;
- Lam, Wan L.;
- Vucic, Emily A.;
- Kremer, Bernd;
- Klussmann, Jens-P.;
- Huebbers, Christian U.
Publication type:
Article
Analysis of Expression and Regulation of AKR1C2 in HPV-Positive and -Negative Oropharyngeal Squamous Cell Carcinoma.
Published in:
Cancers, 2024, v. 16, n. 17, p. 2976, doi. 10.3390/cancers16172976
By:
- Ziogas, Maria;
- Siefer, Oliver;
- Wuerdemann, Nora;
- Balaji, Harini;
- Gross, Elena;
- Drebber, Uta;
- Klussmann, Jens Peter;
- Huebbers, Christian U.
Publication type:
Article
Comprehensive Analysis of VEGFR2 Expression in HPV-Positive and -Negative OPSCC Reveals Differing VEGFR2 Expression Patterns.
Published in:
Cancers, 2021, v. 13, n. 20, p. 5221, doi. 10.3390/cancers13205221
By:
- Uzun, Senem;
- Korkmaz, Yüksel;
- Wuerdemann, Nora;
- Arolt, Christoph;
- Puladi, Behrus;
- Siefer, Oliver G.;
- Dönmez, Hanife G.;
- Hufbauer, Martin;
- Akgül, Baki;
- Klussmann, Jens P.;
- Huebbers, Christian U.
Publication type:
Article
Pathological consequences of VCP mutations on human striated muscle.
Published in:
Brain: A Journal of Neurology, 2007, v. 130, n. 2, p. 381, doi. 10.1093/brain/awl238
By:
- Christian U. Hübbers;
- Christoph S. Clemen
Publication type:
Article
Nuclear translocation of β-catenin and decreased expression of epithelial cadherin in human papillomavirus-positive tonsillar cancer: an early event in human papillomavirus-related tumour progression?
Published in:
Histopathology, 2011, v. 58, n. 7, p. 1117, doi. 10.1111/j.1365-2559.2011.03805.x
By:
- Stenner, Markus;
- Yosef, Basima;
- Huebbers, Christian U.;
- Preuss, Simon F.;
- Dienes, Hans-Peter;
- Speel, Ernst-Jan M.;
- Odenthal, Margarete;
- Klussmann, Jens P.
Publication type:
Article
Upregulation of AKR1C1 and AKR1C3 expression in OPSCC with integrated HPV16 and HPV‐negative tumors is an indicator of poor prognosis.
Published in:
International Journal of Cancer, 2019, v. 144, n. 10, p. 2465, doi. 10.1002/ijc.31954
By:
- Huebbers, Christian U.;
- Verhees, Femke;
- Poluschkin, Leonard;
- Olthof, Nadine C.;
- Kolligs, Jutta;
- Siefer, Oliver G.;
- Henfling, Mieke;
- Ramaekers, Frans C.S.;
- Preuss, Simon F.;
- Beutner, Dirk;
- Seehawer, Julia;
- Drebber, Uta;
- Korkmaz, Yüksel;
- Lam, Wan L.;
- Vucic, Emily A.;
- Kremer, Bernd;
- Klussmann, Jens P.;
- Speel, Ernst‐Jan M.
Publication type:
Article
HPV16 increases the number of migratory cancer stem cells and modulates their miRNA expression profile in oropharyngeal cancer.
Published in:
International Journal of Cancer, 2018, v. 143, n. 6, p. 1426, doi. 10.1002/ijc.31538
By:
- Hufbauer, Martin;
- Maltseva, Margaret;
- Meinrath, Jeannine;
- Lechner, Axel;
- Beutner, Dirk;
- Huebbers, Christian U.;
- Akgül, Baki
Publication type:
Article
Viral load, gene expression and mapping of viral integration sites in HPV16-associated HNSCC cell lines.
Published in:
International Journal of Cancer, 2015, v. 136, n. 5, p. E207, doi. 10.1002/ijc.29112
By:
- Olthof, Nadine C.;
- Huebbers, Christian U.;
- Kolligs, Jutta;
- Henfling, Mieke;
- Ramaekers, Frans C.S.;
- Cornet, Iris;
- Lent‐Albrechts, Josefa A.;
- Stegmann, Alexander P.A.;
- Silling, Steffi;
- Wieland, Ulrike;
- Carey, Thomas E.;
- Walline, Heather M.;
- Gollin, Susanne M.;
- Hoffmann, Thomas K.;
- Winter, Johan;
- Kremer, Bernd;
- Klussmann, Jens P.;
- Speel, Ernst‐Jan M.
Publication type:
Article
P16<sup>INK4A</sup> immunostaining is a strong indicator for high-risk-HPV-associated oropharyngeal carcinomas and dysplasias, but is unreliable to predict low-risk-HPV-infection in head and neck papillomas and laryngeal dysplasias.
Published in:
International Journal of Cancer, 2014, v. 134, n. 9, p. 2108, doi. 10.1002/ijc.28534
By:
- Mooren, Jeroen J.;
- Gültekin, Sibel E.;
- Straetmans, Jos M.J.A.A.;
- Haesevoets, Annick;
- Peutz‐Kootstra, Carine J.;
- Huebbers, Christian U.;
- Dienes, Hans P.;
- Wieland, Ulrike;
- Ramaekers, Frans C.S.;
- Kremer, Bernd;
- Speel, Ernst‐Jan M.;
- Klussmann, Jens P.
Publication type:
Article
Chromosome stability in tonsillar squamous cell carcinoma is associated with HPV16 integration and indicates a favorable prognosis.
Published in:
International Journal of Cancer, 2013, v. 132, n. 8, p. 1781, doi. 10.1002/ijc.27846
By:
- Mooren, Jeroen J.;
- Kremer, Bernd;
- Claessen, Sandra M.H.;
- Voogd, Adri C.;
- Bot, Fredrik J.;
- Peter Klussmann, J.;
- Huebbers, Christian U.;
- Hopman, Anton H.N.;
- Ramaekers, Frans C.S.;
- Speel, Ernst‐Jan M.
Publication type:
Article
Die Bedeutung der Valosin-containing protein (VCP/p97)-Expression in Oropharynxkarzinomen.
Published in:
GMS Current Posters in Otorhinolaryngology: Head & Neck Surgery, 2014, v. 10, p. 1
By:
- Seuthe, Inga M.C.;
- Preuss, Simon F.;
- Drebber, Uta;
- Siefer, Oliver;
- Weinell, Antje;
- Klussmann, Jens Peter;
- Huebbers, Christian U.
Publication type:
Article
Methylation status of HPV16 E2-binding sites classifies subtypes of HPV-associated oropharyngeal cancers.
Published in:
Cancer (0008543X), 2015, v. 121, n. 12, p. 1966, doi. 10.1002/cncr.29315
By:
- Reuschenbach, Miriam;
- Huebbers, Christian U.;
- Prigge, Elena‐Sophie;
- Bermejo, Justo Lorenzo;
- Kalteis, Martin S.;
- Preuss, Simon F.;
- Seuthe, Inga M.C.;
- Kolligs, Jutta;
- Speel, Ernst‐Jan M.;
- Olthof, Nadine;
- Kremer, Bernd;
- Wagner, Steffen;
- Klussmann, Jens P.;
- Vinokurova, Svetlana;
- von Knebel Doeberitz, Magnus
Publication type:
Article

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