Works by Huang, Zhi‐Shu

Results: 35

Bouchardatine analogue alleviates non-alcoholic hepatic fatty liver disease/non-alcoholic steatohepatitis in high-fat fed mice by inhibiting ATP synthase activity.

Published in:

2019

By:

Rao, Yong;
Lu, Yu‐Ting;
Li, Chan;
Song, Qin‐Qin;
Xu, Yao‐Hao;
Xu, Zhao;
Hu, Yu‐Tao;
Yu, Hong;
Gao, Lin;
Gu, Lian‐Quan;
Ye, Ji‐Ming;
Huang, Zhi‐Shu;
Lu, Yu-Ting;
Song, Qin-Qin;
Xu, Yao-Hao;
Hu, Yu-Tao;
Gu, Lian-Quan;
Ye, Ji-Ming;
Huang, Zhi-Shu

Publication type:

journal article

Natural alkaloid bouchardatine ameliorates metabolic disorders in high-fat diet-fed mice by stimulating the sirtuin 1/liver kinase B-1/AMPK axis.

Published in:

2017

By:

Rao, Yong;
Yu, Hong;
Gao, Lin;
Lu, Yu‐Ting;
Xu, Zhao;
Liu, Hong;
Gu, Lian‐Quan;
Ye, Ji‐Ming;
Huang, Zhi‐Shu;
Lu, Yu-Ting;
Gu, Lian-Quan;
Ye, Ji-Ming;
Huang, Zhi-Shu

Publication type:

journal article

Regioselective Electrophilic Addition to Propargylic B(MIDA)s Enabled by β‐Boron Effect.

Published in:

Advanced Science, 2023, v. 10, n. 30, p. 1, doi. 10.1002/advs.202304282

By:

Li, Yin;
Chen, Zhi‐Hao;
Lin, Shuang;
Liu, Yuan;
Qian, Jiasheng;
Li, Qingjiang;
Huang, Zhi‐Shu;
Wang, Honggen

Publication type:

Article

The G-quadruplex ligand, SYUIQ-FM05, targets proto-oncogene c- kit transcription and induces apoptosis in K562 cells.

Published in:

Pharmaceutical Biology, 2013, v. 51, n. 4, p. 447, doi. 10.3109/13880209.2012.738424

By:

Shen, Fei-Hai;
Jin, Jing;
Li, Jia;
Wang, Yan;
Zhu, Shao-Hua;
Lu, Yu-Jing;
Ou, Tian-Miao;
Huang, Zhi-Shu;
Huang, Min;
Huang, Zhi-Ying

Publication type:

Article

Synthesis and Cytotoxicity of 9‐Substituted Benzo[ de ]chromene‐7,8‐dione and 5‐Benzyl‐9‐substituted Benzo[ de ]chromene‐7,8‐dione.

Published in:

Synthetic Communications, 2006, v. 36, n. 18, p. 2667, doi. 10.1080/00397910600764683

By:

Huang, Shi‐Liang;
Luo, Yi;
Huang, Zhi‐Shu;
Wang, Xing‐Yuan;
Bu, Xian‐Zhang;
Liu, Pei‐Qing;
Ma, Lin;
Xie, Bing‐Fen;
Liu, Zong‐Chao;
Li, Yue‐Ming;
Chan, AlbertS. C.

Publication type:

Article

Selective Up-Regulation of Tumor Suppressor Gene Retinoblastoma by Bisacridine Derivative Through Gene Promoter Quadruplex Structures for Cancer Treatment.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 4, p. 1417, doi. 10.3390/ijms26041417

By:

Lin, Xiaomin;
Zhang, Jiahui;
Liang, Jihai;
Ji, Dongsheng;
Huang, Zhi-Shu;
Li, Ding

Publication type:

Article

High-Valent Pentamethylcyclopentadienylcobalt(III) or -iridium(III)-Catalyzed CH Annulation with Alkynes: Synthesis of Heterocyclic Quaternary Ammonium Salts.

Published in:

2016

By:

Lao, Ye ‐ Xing;
Zhang, Shang ‐ Shi;
Liu, Xu ‐ Ge;
Jiang, Chun ‐ Yong;
Wu, Jia ‐ Qiang;
Li, Qingjiang;
Huang, Zhi ‐ Shu;
Wang, Honggen

Publication type:

Other

L‐aspartate ameliorates diet‐induced obesity by increasing adipocyte energy expenditure.

Published in:

Diabetes, Obesity & Metabolism, 2025, v. 27, n. 2, p. 606, doi. 10.1111/dom.16053

By:

Guo, Shi‐Yao;
Hu, Yu‐Tao;
Rao, Yong;
Jiang, Zhi;
Li, Chan;
Lin, Yu‐Wei;
Xu, Shu‐min;
Zhao, Dan‐Dan;
Wei, Li‐yuan;
Huang, Shi‐Liang;
Li, Qing‐Jiang;
Tan, Jia‐Heng;
Chen, Shuo‐Bin;
Huang, Zhi‐Shu

Publication type:

Article

Synthesis of substituted 1,2-benzoquinones and substituted 3-hydroxy-4 (1 H)-pyridinones: Application of oxidation-Michael addition in organic synthesis.

Published in:

Chinese Journal of Chemistry, 1999, v. 17, n. 4, p. 377, doi. 10.1002/cjoc.19990170410

By:

Li, Miao-Sheng;
Ma, Lin;
Zhang, Xiao-Chun;
Huang, Zhi-Shu;
Xiao, Shao-Hua;
Gu, Lian-Quan

Publication type:

Article

Divergent Fluorinations of Vinylcyclopropanes: Ring‐Opening 1,5‐Hydrofluorination and Ring‐Retaining 1,2‐Difluorination.

Published in:

Chemistry - An Asian Journal, 2023, v. 18, n. 16, p. 1, doi. 10.1002/asia.202300476

By:

Yang, Shuang;
Wu, Jun‐Yunzi;
Lin, Shuang;
Pu, Meicen;
Huang, Zhi‐Shu;
Wang, Honggen;
Li, Qingjiang

Publication type:

Article

MYC modulators in cancer: a patent review.

Published in:

Expert Opinion on Therapeutic Patents, 2019, v. 29, n. 5, p. 353, doi. 10.1080/13543776.2019.1612878

By:

Wang, Xiao-Na;
Su, Xiao-Xuan;
Cheng, Sui-Qi;
Sun, Zhi-Yin;
Huang, Zhi-Shu;
Ou, Tian-Miao

Publication type:

Article

2-(2-indolyl-)-4(3 H)-quinazolines derivates as new inhibitors of AChE: design, synthesis, biological evaluation and molecular modelling.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2013, v. 28, n. 3, p. 583, doi. 10.3109/14756366.2012.663363

By:

Li, Zeng;
Wang, Bin;
Hou, Jin-Qiang;
Huang, Shi-Liang;
Ou, Tian-Miao;
Tan, Jia-Heng;
An, Lin-Kun;
Li, Ding;
Gu, Lian-Quan;
Huang, Zhi-Shu

Publication type:

Article

Synthesis and biological evaluation of novel N, N′-bis-methylenedioxybenzyl-alkylenediamines as bivalent anti-Alzheimer disease ligands.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2011, v. 26, n. 5, p. 706, doi. 10.3109/14756366.2010.548329

By:

Luo, Wen;
Li, Yan-Ping;
Tan, Jia-Heng;
Gu, Lian-Quan;
Huang, Zhi-Shu

Publication type:

Article

A new application of click chemistry in situ: development of fluorescent probe for specific G-quadruplex topology.

Published in:

Scientific Reports, 2015, p. 17202, doi. 10.1038/srep17202

By:

Hu, Ming-Hao;
Chen, Xiao;
Chen, Shuo-Bin;
Ou, Tian-Miao;
Yao, Meicun;
Gu, Lian-Quan;
Huang, Zhi-Shu;
Tan, Jia-Heng

Publication type:

Article

Synthesis and Acetylcholinesterase and Butyrylcholinesterase Inhibitory Activities of 7-Alkoxyl Substituted Indolizinoquinoline-5,12-dione Derivatives.

Published in:

Archiv der Pharmazie, 2012, v. 345, n. 3, p. 175, doi. 10.1002/ardp.201100188

By:

Wu, Zu-Ping;
Wu, Xi-Wei;
Shen, Ting;
Li, Yan-Ping;
Cheng, Xi;
Gu, Lian-Quan;
Huang, Zhi-Shu;
An, Lin-Kun

Publication type:

Article

MSN8C: A Promising Candidate for Antitumor Applications as a Novel Catalytic Inhibitor of Topoisomerase II.

Published in:

Molecules, 2023, v. 28, n. 14, p. 5598, doi. 10.3390/molecules28145598

By:

Ou, Jie-Bin;
Huang, Wei-Hao;
Liu, Xing-Zi;
Dai, Guo-Yao;
Wang, Lu;
Huang, Zhi-Shu;
Huang, Shi-Liang

Publication type:

Article

Fluorescent Quinolinium Derivative as Novel Mitochondria Probe and Function Modulator by Targeting Mitochondrial RNA.

Published in:

Molecules, 2023, v. 28, n. 6, p. 2690, doi. 10.3390/molecules28062690

By:

Wang, Bo-Zheng;
Zhou, Ying-Chen;
Lin, Yu-Wei;
Chen, Xiu-Cai;
Yu, Ze-Yi;
Xu, Yao-Hao;
Tan, Jia-Heng;
Huang, Zhi-Shu;
Chen, Shuo-Bin

Publication type:

Article

Development of a Highly Selective and Sensitive Fluorescent Probe for Imaging RNA Dynamics in Live Cells.

Published in:

Molecules, 2022, v. 27, n. 20, p. 6927, doi. 10.3390/molecules27206927

By:

Fang, Lan;
Shao, Wen;
Zeng, Shu-Tang;
Tang, Gui-Xue;
Yan, Jia-Tong;
Chen, Shuo-Bin;
Huang, Zhi-Shu;
Tan, Jia-Heng;
Chen, Xiu-Cai

Publication type:

Article

Discovery of Quinacrine as a Potent Topo II and Hsp90 Dual-Target Inhibitor, Repurposing for Cancer Therapy.

Published in:

Molecules, 2022, v. 27, n. 17, p. 5561, doi. 10.3390/molecules27175561

By:

Pan, Xin;
Mao, Teng-yu;
Mai, Yan-wen;
Liang, Cheng-cheng;
Huang, Wei-hao;
Rao, Yong;
Huang, Zhi-shu;
Huang, Shi-liang

Publication type:

Article

N-Halosuccinimide enables cascade oxidative trifluorination and halogenative cyclization of tryptamine-derived isocyanides.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-53271-9

By:

Wu, Jun-Yunzi;
Huang, Long-Ling;
Fu, Jia-Luo;
Li, Jia-Yi;
Lin, Shuang;
Yang, Shuang;
Huang, Zhi-Shu;
Wang, Honggen;
Li, Qingjiang

Publication type:

Article

N-Halosuccinimide enables cascade oxidative trifluorination and halogenative cyclization of tryptamine-derived isocyanides.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-53271-9

By:

Wu, Jun-Yunzi;
Huang, Long-Ling;
Fu, Jia-Luo;
Li, Jia-Yi;
Lin, Shuang;
Yang, Shuang;
Huang, Zhi-Shu;
Wang, Honggen;
Li, Qingjiang

Publication type:

Article

Photochemical Radical C–H Halogenation of Benzyl N‐Methyliminodiacetyl (MIDA) Boronates: Synthesis of α‐Functionalized Alkyl Boronates.

Published in:

Angewandte Chemie, 2021, v. 133, n. 7, p. 3496, doi. 10.1002/ange.202011872

By:

Yang, Ling;
Tan, Dong‐Hang;
Fan, Wen‐Xin;
Liu, Xu‐Ge;
Wu, Jia‐Qiang;
Huang, Zhi‐Shu;
Li, Qingjiang;
Wang, Honggen

Publication type:

Article

Tracking the Dynamic Folding and Unfolding of RNA G‐Quadruplexes in Live Cells.

Published in:

Angewandte Chemie, 2018, v. 130, n. 17, p. 4792, doi. 10.1002/ange.201801999

By:

Chen, Xiu‐Cai;
Chen, Shuo‐Bin;
Dai, Jing;
Yuan, Jia‐Hao;
Ou, Tian‐Miao;
Huang, Zhi‐Shu;
Tan, Jia‐Heng

Publication type:

Article

New insights from molecular dynamic simulation studies of the multiple binding modes of a ligand with G-quadruplex DNA.

Published in:

Journal of Computer-Aided Molecular Design, 2012, v. 26, n. 12, p. 1355, doi. 10.1007/s10822-012-9619-1

By:

Hou, Jin-Qiang;
Chen, Shuo-Bin;
Tan, Jia-Heng;
Luo, Hai-Bin;
Li, Ding;
Gu, Lian-Quan;
Huang, Zhi-Shu

Publication type:

Article

A novel HSF1 activator ameliorates non‐alcoholic steatohepatitis by stimulating mitochondrial adaptive oxidation.

Published in:

British Journal of Pharmacology, 2022, v. 179, n. 7, p. 1411, doi. 10.1111/bph.15727

By:

Rao, Yong;
Li, Chan;
Hu, Yu‐Tao;
Xu, Yao‐Hao;
Song, Bing‐Bing;
Guo, Shi‐Yao;
Jiang, Zhi;
Zhao, Dan‐Dan;
Chen, Shuo‐Bin;
Tan, Jia‐Heng;
Huang, Shi‐Liang;
Li, Qing‐Jiang;
Wang, Xiao‐Jun;
Zhang, Ying‐Jun;
Ye, Ji‐Ming;
Huang, Zhi‐Shu

Publication type:

Article

Visualization of ligand-induced c-MYC duplex–quadruplex transition and direct exploration of the altered c-MYC DNA-protein interactions in cells.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 8, p. 4246, doi. 10.1093/nar/gkac245

By:

Yuan, Jia-Hao;
Tu, Jia-Li;
Liu, Guo-Cai;
Chen, Xiu-Cai;
Huang, Zhi-Shu;
Chen, Shuo-Bin;
Tan, Jia-Heng

Publication type:

Article

Upregulation of BCL-2 by acridone derivative through gene promoter i-motif for alleviating liver damage of NAFLD/NASH.

Published in:

Nucleic Acids Research, 2020, v. 48, n. 15, p. 8255, doi. 10.1093/nar/gkaa615

By:

Li, Xiaoya;
Wang, Jing;
Gong, Xue;
Zhang, Meiling;
Kang, Shuangshuang;
Shu, Bing;
Wei, Zuzhuang;
Huang, Zhi-Shu;
Li, Ding

Publication type:

Article

Transcriptional regulation of telomeric repeat-containing RNA by acridine derivatives.

Published in:

RNA Biology, 2021, v. 18, n. 12, p. 2261, doi. 10.1080/15476286.2021.1899652

By:

Kang, Shuangshuang;
Cao, Jiaojiao;
Zhang, Meiling;
Li, Xiaoya;
Guo, Qian-Liang;
Zeng, Huang;
Wei, Zuzhuang;
Gong, Xue;
Wang, Jing;
Liu, Bobo;
Shu, Bing;
Xu, Xiaoli;
Huang, Zhi-Shu;
Li, Ding

Publication type:

Article

Photochemical Radical C–H Halogenation of Benzyl N‐Methyliminodiacetyl (MIDA) Boronates: Synthesis of α‐Functionalized Alkyl Boronates.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 7, p. 3454, doi. 10.1002/anie.202011872

By:

Yang, Ling;
Tan, Dong‐Hang;
Fan, Wen‐Xin;
Liu, Xu‐Ge;
Wu, Jia‐Qiang;
Huang, Zhi‐Shu;
Li, Qingjiang;
Wang, Honggen

Publication type:

Article

Tracking the Dynamic Folding and Unfolding of RNA G‐Quadruplexes in Live Cells.

Published in:

Angewandte Chemie International Edition, 2018, v. 57, n. 17, p. 4702, doi. 10.1002/anie.201801999

By:

Chen, Xiu‐cai;
Chen, Shuo‐bin;
Dai, Jing;
Yuan, Jia‐hao;
Ou, Tian‐miao;
Huang, Zhi‐shu;
Tan, Jia‐heng

Publication type:

Article

Investigation on fragmentation pathways of rutaecarpine and its two derivatives using electrospray ionization ion-trap time-of-flight tandem mass spectrometry.

Published in:

Rapid Communications in Mass Spectrometry: RCM, 2010, v. 24, n. 18, p. 2781, doi. 10.1002/rcm.4697

By:

Wang, Bin;
Chu, Wen-Yi;
Li, Zeng;
Hou, Jin-Qiang;
Huang, Shi-Liang;
Ou, Tian-Miao;
Tan, Jia-Heng;
An, Lin-Kun;
Li, Ding;
Gu, Lian-Quan;
Huang, Zhi-Shu

Publication type:

Article

New Therapeutic Method for Alleviating Damage of Acute Kidney Injury Through BCL-2 Gene Promoter I-Motif.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 22, p. 12028, doi. 10.3390/ijms252212028

By:

Ji, Dongsheng;
Zhang, Jiahui;
Liang, Jihai;
Wang, Jing;
Li, Xiaoya;
Huang, Zhi-Shu;
Li, Ding

Publication type:

Article

Development of a Smart Fluorescent Probe Specifically Interacting with C-Myc I-Motif.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 7, p. 3872, doi. 10.3390/ijms23073872

By:

Wei, Zuzhuang;
Liu, Bobo;
Lin, Xiaomin;
Wang, Jing;
Huang, Zhi-Shu;
Li, Ding

Publication type:

Article

Natural Alkaloids and Heterocycles as G-Quadruplex Ligands and Potential Anticancer Agents.

Published in:

Molecules, 2018, v. 23, n. 2, p. 493, doi. 10.3390/molecules23020493

By:

Che, Tong;
Wang, Yu-Qing;
Huang, Zhou-Li;
Tan, Jia-Heng;
Huang, Zhi-Shu;
Chen, Shuo-Bin

Publication type:

Article

G-Quadruplexes: Targets in Anticancer Drug Design.

Published in:

ChemMedChem, 2008, v. 3, n. 5, p. 690, doi. 10.1002/cmdc.200700300

By:

Ou, Tian-miao;
Lu, Yu-jing;
Tan, Jia-heng;
Huang, Zhi-shu;
Wong, Kwok-Yin;
Gu, Lian-quan

Publication type:

Article